Model Description Sheet
... neurotoxin, causing muscle paralysis in the host by blocking the release of the neurotransmitter, acetylcholine, from motor neurons associated with skeletal muscle. Despite this toxicity, BoNT/A is used pharmaceutically as a treatment for numerous neurological diseases, including migraines, dystonia ...
... neurotoxin, causing muscle paralysis in the host by blocking the release of the neurotransmitter, acetylcholine, from motor neurons associated with skeletal muscle. Despite this toxicity, BoNT/A is used pharmaceutically as a treatment for numerous neurological diseases, including migraines, dystonia ...
MOLECULAR EVOLUTION
... The higher error rate during mtDNA replication and repair. mtDNA polymerases have no proofreading ability. Higher concentrations of mutagens such as free radicals resulting from metabolic processes. Less selective pressure because there are many of them within the cell; changes are less detrimental. ...
... The higher error rate during mtDNA replication and repair. mtDNA polymerases have no proofreading ability. Higher concentrations of mutagens such as free radicals resulting from metabolic processes. Less selective pressure because there are many of them within the cell; changes are less detrimental. ...
Small Business Success on the Web
... use H2O to break apart monomers reverse of condensation reaction H2O is split into H and OH H & OH group attach where the covalent ...
... use H2O to break apart monomers reverse of condensation reaction H2O is split into H and OH H & OH group attach where the covalent ...
RiceRBP: a resource for experimentally identified RNA
... cytoskeleton-associated transport, localization, translation, and RNA stability (Wilkinson and Shyu, 2001; Dreyfuss et al., 2002; Martin and Ephrussi, 2009). RNA localization has been wellcharacterized in yeast and metazoans, but relatively few studies have been reported in plants (Okita and Choi, 2 ...
... cytoskeleton-associated transport, localization, translation, and RNA stability (Wilkinson and Shyu, 2001; Dreyfuss et al., 2002; Martin and Ephrussi, 2009). RNA localization has been wellcharacterized in yeast and metazoans, but relatively few studies have been reported in plants (Okita and Choi, 2 ...
Small Business Success on the Web
... use H2O to break apart monomers reverse of condensation reaction H2O is split into H and OH H & OH group attach where the covalent ...
... use H2O to break apart monomers reverse of condensation reaction H2O is split into H and OH H & OH group attach where the covalent ...
Text S1 Y2H Interactome Mapping The literature was curated to
... found in CF by multiple studies; 75% of the eliminated ORFs encode proteins that were identified in CF in only a single proteomic study, in comparison to those that remained for which 32% were detected in only a single study. From the final list, 339 ORFs that were sequence validated were provided b ...
... found in CF by multiple studies; 75% of the eliminated ORFs encode proteins that were identified in CF in only a single proteomic study, in comparison to those that remained for which 32% were detected in only a single study. From the final list, 339 ORFs that were sequence validated were provided b ...
Sophistication of foldamer form and function in
... behaved aggregates with non-discrete stoichiometries [54,55]. The elegant efforts of Seebach and co-workers [56,57] towards the b-peptide equivalent of an a-peptide Zn-finger [58] came to fruition in the form of a b-hexadecapeptide that was designed to assemble into the characteristic Zn-finger fold ...
... behaved aggregates with non-discrete stoichiometries [54,55]. The elegant efforts of Seebach and co-workers [56,57] towards the b-peptide equivalent of an a-peptide Zn-finger [58] came to fruition in the form of a b-hexadecapeptide that was designed to assemble into the characteristic Zn-finger fold ...
New Title - Gravette School District
... a polymer may be identical, like the links on a metal watch band; or the monomers may be different, like the beads in a multicolored necklace. Figure 2–12 illustrates the formation of a polymer from more than one type of monomer. It would be difficult to study the millions of organic compounds if th ...
... a polymer may be identical, like the links on a metal watch band; or the monomers may be different, like the beads in a multicolored necklace. Figure 2–12 illustrates the formation of a polymer from more than one type of monomer. It would be difficult to study the millions of organic compounds if th ...
Glucose M9Y Glucose M9Y medium, used to cultivate E. coli, is a
... supplemented with yeast extract. It is based on M9 salts6 with a pH of 6.9±0.2 and employs glucose as the carbon source. Alternative carbon sources may be substituted. Buffering is provided by a sodium-potassium phosphate system. Ammonium chloride provides a nitrogen source. Yeast extract is added t ...
... supplemented with yeast extract. It is based on M9 salts6 with a pH of 6.9±0.2 and employs glucose as the carbon source. Alternative carbon sources may be substituted. Buffering is provided by a sodium-potassium phosphate system. Ammonium chloride provides a nitrogen source. Yeast extract is added t ...
Multivalent cross-linking of actin filaments and microtubules through
... Microtubule-associated proteins regulate microtubule dynamics, bundle actin filaments and cross-link actin filaments with microtubules. In addition, aberrant interaction of the microtubule-associated protein Tau with filamentous actin is connected to synaptic impairment in Alzheimer’s disease. Here ...
... Microtubule-associated proteins regulate microtubule dynamics, bundle actin filaments and cross-link actin filaments with microtubules. In addition, aberrant interaction of the microtubule-associated protein Tau with filamentous actin is connected to synaptic impairment in Alzheimer’s disease. Here ...
Avirulence proteins from haustoria
... plant pathogens including viruses, bacteria and fungi. It is generally thought that these proteins are pathogenicity effectors with positive roles in establishing infection, which the plant has evolved to recognize as an indicator of invasion. For instance, pathogenic bacteria use the FEMS Microbiol ...
... plant pathogens including viruses, bacteria and fungi. It is generally thought that these proteins are pathogenicity effectors with positive roles in establishing infection, which the plant has evolved to recognize as an indicator of invasion. For instance, pathogenic bacteria use the FEMS Microbiol ...
Sp3 Represses Gene Expression via the Titration of Promoter
... have shown previously that Sp1 and Sp3 stimulate transcription of the DHFR promoter and that Sp1/Sp3-mediated transcription is repressed by two isoforms of Sp3, termed M1 and M2, that arise via internal translational initiation (31, 33, 37). To determine whether these results were likely to reflect ...
... have shown previously that Sp1 and Sp3 stimulate transcription of the DHFR promoter and that Sp1/Sp3-mediated transcription is repressed by two isoforms of Sp3, termed M1 and M2, that arise via internal translational initiation (31, 33, 37). To determine whether these results were likely to reflect ...
occasional article intracellular protein degradation: from a vague
... mammalian tissues are in a dynamic state. Moreover, our experiments have shown that the proteins of growing E. coli are static. Therefore it seems necessary to conclude that the synthesis and maintenance of proteins within growing cells is not necessarily or inherently associated with a ‘dynamic sta ...
... mammalian tissues are in a dynamic state. Moreover, our experiments have shown that the proteins of growing E. coli are static. Therefore it seems necessary to conclude that the synthesis and maintenance of proteins within growing cells is not necessarily or inherently associated with a ‘dynamic sta ...
A simple calculus for proteins and cells
... massive parallelism and concurrency of interactions, and to analyse the overall behaviour. There are two features of process calculi that are particularly relevant to biological systems. The first one is about the syntax. In process calculi, the syntax of the terms determines their capacity to inter ...
... massive parallelism and concurrency of interactions, and to analyse the overall behaviour. There are two features of process calculi that are particularly relevant to biological systems. The first one is about the syntax. In process calculi, the syntax of the terms determines their capacity to inter ...
Ammonia-Nitrogen in Fermented Feeds - Agri
... Ammonia-N in silage is produced by the breakdown of protein by either plant proteolytic enzymes, or clostridial microorganisms (secondary fermentation). Although NH 3-N is not considered as protein (Nonprotein nitrogen-NPN), it provides N that can be used by rumen bacteria to synthesize microbial pr ...
... Ammonia-N in silage is produced by the breakdown of protein by either plant proteolytic enzymes, or clostridial microorganisms (secondary fermentation). Although NH 3-N is not considered as protein (Nonprotein nitrogen-NPN), it provides N that can be used by rumen bacteria to synthesize microbial pr ...
De Robertis 1.pm
... CR domains of the type present in Chordin are found in many other extracellular space proteins. These include the fibrillar procollagens (type I, III and V), amnionless, neuralin-1 and 2, CRIM-1, crossveinless-2 and CTGF. Neuralins contain three cysteine-rich domains and can bind Tsg, which promotes ...
... CR domains of the type present in Chordin are found in many other extracellular space proteins. These include the fibrillar procollagens (type I, III and V), amnionless, neuralin-1 and 2, CRIM-1, crossveinless-2 and CTGF. Neuralins contain three cysteine-rich domains and can bind Tsg, which promotes ...
fibulins: a versatile family of extracellular matrix proteins
... identity with the other fibulins10,14 (FIG. 1). They have a unique amino-terminal domain I, which seems to be a modified cbEGF-like module that maintains its calcium-binding property (FIG. 1). The structures of fibulins or their individual domains have not, so far, been determined at atomic resoluti ...
... identity with the other fibulins10,14 (FIG. 1). They have a unique amino-terminal domain I, which seems to be a modified cbEGF-like module that maintains its calcium-binding property (FIG. 1). The structures of fibulins or their individual domains have not, so far, been determined at atomic resoluti ...
Sample Preparation Guidelines for 2
... Note: If samples contain components not compatible with DIGE experiment, remove these contaminants by protein precipitation. A number of 2D clean-up kits are commercially available. After protein clean-up, redissolve the protein pellet with a compatible lysis buffer. Be sure to make the final protei ...
... Note: If samples contain components not compatible with DIGE experiment, remove these contaminants by protein precipitation. A number of 2D clean-up kits are commercially available. After protein clean-up, redissolve the protein pellet with a compatible lysis buffer. Be sure to make the final protei ...
Herpesvirus Saimiri-induced Proteins in Lyrically Infected Cells. I
... Use ofinhibitors of DNA synthesis. DNA synthesis was inhibited with three different drugs: hydroxyurea (HU, 4 mg/ml, Sigma), cytosine arabinoside (Ara-C, 50 gg/ml, Sigma) and phosphonoacetic acid (PAA, 50 ~tg/ml, a gift from Abbott Laboratories); stock solutions were prepared as 100 × concentrates i ...
... Use ofinhibitors of DNA synthesis. DNA synthesis was inhibited with three different drugs: hydroxyurea (HU, 4 mg/ml, Sigma), cytosine arabinoside (Ara-C, 50 gg/ml, Sigma) and phosphonoacetic acid (PAA, 50 ~tg/ml, a gift from Abbott Laboratories); stock solutions were prepared as 100 × concentrates i ...
Text S1.
... “For the smaller non-polar residues this number is equal to the maximum area loss that could occur in going from an isolated α-helix to a fully buried environment in the complex. For the larger non-polar residues only a fraction of this value is used since they can never be totally buried in a singl ...
... “For the smaller non-polar residues this number is equal to the maximum area loss that could occur in going from an isolated α-helix to a fully buried environment in the complex. For the larger non-polar residues only a fraction of this value is used since they can never be totally buried in a singl ...
domain alignments - Oxford Academic
... proteins in Entrez. CDART, which stores that information, can be invoked from within Entrez to visualize domain architectures (6). Proteins in Entrez can now be neighboured by similar domain architecture, in addition to sequence similarity as detected by BLAST (7). Conserved Domains are neighboured ...
... proteins in Entrez. CDART, which stores that information, can be invoked from within Entrez to visualize domain architectures (6). Proteins in Entrez can now be neighboured by similar domain architecture, in addition to sequence similarity as detected by BLAST (7). Conserved Domains are neighboured ...
Aim of the lab - Institute of Microelectronics
... Preparation of PEGylated liposomes incorporating at their surface targeting ligands and transporting agents. Application of functional liposomes in cancer treatment and other deceases Complexes of cationic liposomes with DNA for gene therapy applications Cyclodextrins as molecular carriers (I. ...
... Preparation of PEGylated liposomes incorporating at their surface targeting ligands and transporting agents. Application of functional liposomes in cancer treatment and other deceases Complexes of cationic liposomes with DNA for gene therapy applications Cyclodextrins as molecular carriers (I. ...
Intrinsically disordered proteins
An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure. IDPs cover a spectrum of states from fully unstructured to partially structured and include random coils, (pre-)molten globules, and large multi-domain proteins connected by flexible linkers. They constitute one of the main types of protein (alongside globular, fibrous and membrane proteins).The discovery of IDPs has challenged the traditional protein structure paradigm, that protein function depends on a fixed three-dimensional structure. This dogma has been challenged over the last decades by increasing evidence from various branches of structural biology, suggesting that protein dynamics may be highly relevant for such systems. Despite their lack of stable structure, IDPs are a very large and functionally important class of proteins. In some cases, IDPs can adopt a fixed three-dimensional structure after binding to other macromolecules.