Protein Sorting to the Storage Vacuoles of Plants: A Critical Appraisal
... released to the cell exterior by regulated exocytosis (31). In some cells, e.g. platelets, neutrophils and melanosomes, there is good evidence that such hybrid organelles co-exist in the same cell with conventional lysosomes (32,33). Conversely, under some conditions, mammalian cells can store large ...
... released to the cell exterior by regulated exocytosis (31). In some cells, e.g. platelets, neutrophils and melanosomes, there is good evidence that such hybrid organelles co-exist in the same cell with conventional lysosomes (32,33). Conversely, under some conditions, mammalian cells can store large ...
Model Description Sheet
... storing potential using the protein myoglobin. Myoglobin’s structure has been known for decades, but researchers are still trying to determine just how myoglobin functions. Found in muscle tissue, myoglobin stores O2, a molecule needed to produce chemical energy. Toxic ligands, such as carbon monoxi ...
... storing potential using the protein myoglobin. Myoglobin’s structure has been known for decades, but researchers are still trying to determine just how myoglobin functions. Found in muscle tissue, myoglobin stores O2, a molecule needed to produce chemical energy. Toxic ligands, such as carbon monoxi ...
An in silico analysis of the mitochondrial protein import apparatus of
... extensive cis and trans splicing of introns, [12], relatively slow rates of mutations [13,14], extensive editing of mRNA [15] and incorporation of foreign DNA [16]. Another notable feature is the presence of a branched respiratory chain [17]. Although fungi contain alternative NAD(P)H dehydrogenases ...
... extensive cis and trans splicing of introns, [12], relatively slow rates of mutations [13,14], extensive editing of mRNA [15] and incorporation of foreign DNA [16]. Another notable feature is the presence of a branched respiratory chain [17]. Although fungi contain alternative NAD(P)H dehydrogenases ...
A protein domain interaction interface database: InterPare | BMC
... Background: Most proteins function by interacting with other molecules. Their interaction interfaces are highly conserved throughout evolution to avoid undesirable interactions that lead to fatal disorders in cells. Rational drug discovery includes computational methods to identify the interaction s ...
... Background: Most proteins function by interacting with other molecules. Their interaction interfaces are highly conserved throughout evolution to avoid undesirable interactions that lead to fatal disorders in cells. Rational drug discovery includes computational methods to identify the interaction s ...
Vipp1: a very important protein in plastids?!
... ª The Author [2011]. Published by Oxford University Press [on behalf of the Society for Experimental Biology]. All rights reserved. For Permissions, please e-mail: [email protected] ...
... ª The Author [2011]. Published by Oxford University Press [on behalf of the Society for Experimental Biology]. All rights reserved. For Permissions, please e-mail: [email protected] ...
Identification and characterization of DNA sequences that prevent
... majority of GR binding occurring at preexisting loci of accessible chromatin as specified by DNase I sensitivity assays (2). Furthermore, nucleosome presence and positioning influence GR binding (3,4) and DNA methylation correlates with TF binding and might directly interfere with the ability of TFs ...
... majority of GR binding occurring at preexisting loci of accessible chromatin as specified by DNase I sensitivity assays (2). Furthermore, nucleosome presence and positioning influence GR binding (3,4) and DNA methylation correlates with TF binding and might directly interfere with the ability of TFs ...
GLYCEMIC CONTROL TO REDUCE ADRENAL STRESS
... healthy. However, it has been proven that an excess of carbohydrates to protein results in excess levels of insulin. Excess levels of insulin cause adrenal stress, including hypoglycemia. In order to normalize blood sugar, the adrenals have to produce increased levels of cortisol and epinephrine. Th ...
... healthy. However, it has been proven that an excess of carbohydrates to protein results in excess levels of insulin. Excess levels of insulin cause adrenal stress, including hypoglycemia. In order to normalize blood sugar, the adrenals have to produce increased levels of cortisol and epinephrine. Th ...
Recent advances in plant cell wall proteomics
... Indeed, proteomic studies made on cell walls revealed leaderless proteins mixed with secreted proteins, many of which have well-known functions inside the cell. There have been many discussions about the possibility of finding non-canonical proteins in plant cell walls [7, 36]. Are they bona fide s ...
... Indeed, proteomic studies made on cell walls revealed leaderless proteins mixed with secreted proteins, many of which have well-known functions inside the cell. There have been many discussions about the possibility of finding non-canonical proteins in plant cell walls [7, 36]. Are they bona fide s ...
Analysis of protein carbonylation
... characterized by analytical parameters such as sensitivity, precision, reproducibility, measurement interval, ...
... characterized by analytical parameters such as sensitivity, precision, reproducibility, measurement interval, ...
Adhesins and invasins of pathogenic bacteria: a
... events are also observed following binding of growth factors to their receptors [24]. Subsequently, the tyrosine kinase c-Met, the receptor for hepatocyte growth factor (HGF), was identified as InlB receptor on mammalian cells [25]. c-Met is expressed on both epithelial and endothelial cells. Upon H ...
... events are also observed following binding of growth factors to their receptors [24]. Subsequently, the tyrosine kinase c-Met, the receptor for hepatocyte growth factor (HGF), was identified as InlB receptor on mammalian cells [25]. c-Met is expressed on both epithelial and endothelial cells. Upon H ...
Finding a way to the nucleus - Purdue University
... effector proteins to host cells through a T4SS is also important for animal and human pathogenesis by a number of bacteria, including Helicobacter, Brucella, Bordetella, Bartonella, and Legionella species [5]. In addition to VirD2, of special importance for plant genetic transformation is VirE2, a s ...
... effector proteins to host cells through a T4SS is also important for animal and human pathogenesis by a number of bacteria, including Helicobacter, Brucella, Bordetella, Bartonella, and Legionella species [5]. In addition to VirD2, of special importance for plant genetic transformation is VirE2, a s ...
+TIPs and Microtubule Regulation. The Beginning of the Plus End in
... MT assembly and organization are regulated by the inherent dynamics of the tubule and by an array of regulatory proteins termed MAPs (MT-associated proteins). The inherent dynamics, or dynamic instability, of MTs is governed by their ends, which exhibit rapid transitions between growing and shrinkin ...
... MT assembly and organization are regulated by the inherent dynamics of the tubule and by an array of regulatory proteins termed MAPs (MT-associated proteins). The inherent dynamics, or dynamic instability, of MTs is governed by their ends, which exhibit rapid transitions between growing and shrinkin ...
Journal of Medical Microbiology
... A pool of heparan sulphate-binding proteins (HSBPs) from Helicobacter pylori culture supernates was obtained by sequential ammonium sulphate precipitation and af®nity chromatography on heparin-Sepharose. The chromatographic procedure yielded one major fraction that contained proteins with heparan su ...
... A pool of heparan sulphate-binding proteins (HSBPs) from Helicobacter pylori culture supernates was obtained by sequential ammonium sulphate precipitation and af®nity chromatography on heparin-Sepharose. The chromatographic procedure yielded one major fraction that contained proteins with heparan su ...
Use the following information and image to answer the questions
... 1. Proteins are composed of amino acid molecules linked together by peptide bonds. C, H, N, S, and O are typical atoms that compose amino acids. 2. The amino acids contain amino and carboxyl groups. Primary, secondary, tertiary, and quaternary structures of a protein molecule are necessary for the p ...
... 1. Proteins are composed of amino acid molecules linked together by peptide bonds. C, H, N, S, and O are typical atoms that compose amino acids. 2. The amino acids contain amino and carboxyl groups. Primary, secondary, tertiary, and quaternary structures of a protein molecule are necessary for the p ...
Human CHMP6, a myristoylated ESCRT-III protein, interacts directly
... family. They are structurally similar to the yeast ESCRT-III components, and are thus candidates for the human counterparts playing still unclarified roles in invagination of endosomal membranes to form MVBs [16]. They are coiled-coil proteins of approx. 200 amino acid residues and exhibit an uneven ...
... family. They are structurally similar to the yeast ESCRT-III components, and are thus candidates for the human counterparts playing still unclarified roles in invagination of endosomal membranes to form MVBs [16]. They are coiled-coil proteins of approx. 200 amino acid residues and exhibit an uneven ...
COS 597c: Topics in Computational Molecular Biology Lecturer: Mona Singh
... been called, among other things, weight matrices, templates, and position specific scoring matrices) for motifs or sequence families. There are many websites that contain collections of amino acid sequence motifs that indicate particular structural of functional elements; searches of these websites ...
... been called, among other things, weight matrices, templates, and position specific scoring matrices) for motifs or sequence families. There are many websites that contain collections of amino acid sequence motifs that indicate particular structural of functional elements; searches of these websites ...
Selenocysteine: The 21 Amino Acid
... by the genes sel A and sel D. The gene sel D requires the presence of selenium which it converts to selenophosphate at the cost of one ATP molecule. Selenophosphate contains a high energy bond and is thus considered “activated.” The product of sel A converts the charged serine residue to a more acti ...
... by the genes sel A and sel D. The gene sel D requires the presence of selenium which it converts to selenophosphate at the cost of one ATP molecule. Selenophosphate contains a high energy bond and is thus considered “activated.” The product of sel A converts the charged serine residue to a more acti ...
8. ARTÍCULOS
... F-box motif, both generally recognized as hallmarks of such enzymes), we checked whether M2-PK might be a ubiquitination substrate of HERC1. Nevertheless, since ubiquitination of M2-PK has not been described, we ¢rst set about determining whether M2-PK undergoes ubiquitination under physiological co ...
... F-box motif, both generally recognized as hallmarks of such enzymes), we checked whether M2-PK might be a ubiquitination substrate of HERC1. Nevertheless, since ubiquitination of M2-PK has not been described, we ¢rst set about determining whether M2-PK undergoes ubiquitination under physiological co ...
an introduction to bioinorganic chemistry
... specific in their metal ion requirements in that only certain metal ions, in specified oxidation states can fulfill the necessary catalytic or structural requirements. A large number of metal ions are involved in biological processes. This can be verified by just going through the protein data banks ...
... specific in their metal ion requirements in that only certain metal ions, in specified oxidation states can fulfill the necessary catalytic or structural requirements. A large number of metal ions are involved in biological processes. This can be verified by just going through the protein data banks ...
Powerpoint slides
... If we were able to evaluate 109 conformations per second, this would still keep us busy 4 x 10259 times the current age of the universe There are optimized ab initio prediction algorithms available as well as fold recognition algorithms that use threading (compares protein folds with know fold struc ...
... If we were able to evaluate 109 conformations per second, this would still keep us busy 4 x 10259 times the current age of the universe There are optimized ab initio prediction algorithms available as well as fold recognition algorithms that use threading (compares protein folds with know fold struc ...
1 Introduction - diss.fu
... termed the L1, central protuberance, and the L7/L12 stalk (Frank, 1989; Stark et al., 1995). The standard electron microscopy has been improved by embedding the observed object in amorphous water via freezing in liquid nitrogen or helium. This method - cryo-electron microscopy (cryo-EM) - was extens ...
... termed the L1, central protuberance, and the L7/L12 stalk (Frank, 1989; Stark et al., 1995). The standard electron microscopy has been improved by embedding the observed object in amorphous water via freezing in liquid nitrogen or helium. This method - cryo-electron microscopy (cryo-EM) - was extens ...
What Does the Microsporidian E. cuniculi Tell Us About the Origin of
... S. cerevisiae proteins with proteins of D. melanogaster, C. elegans, A. thaliana, and G. lamblia and those of 44 bacteria and archaea species. We used a blast score of 55 bits. This score was based on our consultation with experts in bioinformatics, as the Giardia database was in contigs only and wa ...
... S. cerevisiae proteins with proteins of D. melanogaster, C. elegans, A. thaliana, and G. lamblia and those of 44 bacteria and archaea species. We used a blast score of 55 bits. This score was based on our consultation with experts in bioinformatics, as the Giardia database was in contigs only and wa ...
chemistry bulletin 2005
... homologous proteins known as P-loop NTPases that share a mononucleotide-binding fold and catalyze hydrolysis of the β−γ phosphate ester bond of the nucleotide. Of all the nucleotide binding folds, the P-loop fold is by far the most abundant; it has been estimated that 10-18% of predicted gene produ ...
... homologous proteins known as P-loop NTPases that share a mononucleotide-binding fold and catalyze hydrolysis of the β−γ phosphate ester bond of the nucleotide. Of all the nucleotide binding folds, the P-loop fold is by far the most abundant; it has been estimated that 10-18% of predicted gene produ ...
Intrinsically disordered proteins
An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure. IDPs cover a spectrum of states from fully unstructured to partially structured and include random coils, (pre-)molten globules, and large multi-domain proteins connected by flexible linkers. They constitute one of the main types of protein (alongside globular, fibrous and membrane proteins).The discovery of IDPs has challenged the traditional protein structure paradigm, that protein function depends on a fixed three-dimensional structure. This dogma has been challenged over the last decades by increasing evidence from various branches of structural biology, suggesting that protein dynamics may be highly relevant for such systems. Despite their lack of stable structure, IDPs are a very large and functionally important class of proteins. In some cases, IDPs can adopt a fixed three-dimensional structure after binding to other macromolecules.