Gene Section BRD4 (bromodomain containing 4) Atlas of Genetics and Cytogenetics
... A striking feature of BRD4 is its association with euchromatic regions of mitotic chromosomes. By this association, the protein exerts its function as regulator of cell cycle progression from G2 to M but also in the G1 to S transition. It has also been suggested that the association of BRD4 to chrom ...
... A striking feature of BRD4 is its association with euchromatic regions of mitotic chromosomes. By this association, the protein exerts its function as regulator of cell cycle progression from G2 to M but also in the G1 to S transition. It has also been suggested that the association of BRD4 to chrom ...
KASH `n Karry: The KASH domain family of cargo
... zyg-12 mutants die as embryos due to cellular aneuploidy. In addition, ZYG-12 protein isoforms are small. There are three ZYG-12 isoforms (Fig. 4), two that contain KASH domains (B and C) and one that does not (A). Also, N-terminal to its KASH domain, ZYG-12 is similar to another protein called Hook ...
... zyg-12 mutants die as embryos due to cellular aneuploidy. In addition, ZYG-12 protein isoforms are small. There are three ZYG-12 isoforms (Fig. 4), two that contain KASH domains (B and C) and one that does not (A). Also, N-terminal to its KASH domain, ZYG-12 is similar to another protein called Hook ...
3. Orm proteins
... •Without Orm mediated brake on SPT there is toxic accumulation of sphingolipids. •Normal intermidiate phosphorylation will give chance to a rapid responce. ...
... •Without Orm mediated brake on SPT there is toxic accumulation of sphingolipids. •Normal intermidiate phosphorylation will give chance to a rapid responce. ...
bi6103-20feb04 - NUS School of Computing
... approximately known, we “dilute” by unlabeling 3 residues on each side of a helix boundary to accommodate this • Stage 2: Baum-Welch is used for maximum likelihood estimation from “relabeled” training data. The original training data are diluted as by unlabeling 5 residues on each side of a helix bo ...
... approximately known, we “dilute” by unlabeling 3 residues on each side of a helix boundary to accommodate this • Stage 2: Baum-Welch is used for maximum likelihood estimation from “relabeled” training data. The original training data are diluted as by unlabeling 5 residues on each side of a helix bo ...
the simple quad method - New Moon Family Acupuncture
... Carbohydrate, and a small amount of Fat. Your serving size for the entire meal should be about the size of your two hands cupped together. This is the amount that your stomach can comfortably handle at each meal. An example would be baked chicken, cooked carrots, salad and a small baked potato. Or g ...
... Carbohydrate, and a small amount of Fat. Your serving size for the entire meal should be about the size of your two hands cupped together. This is the amount that your stomach can comfortably handle at each meal. An example would be baked chicken, cooked carrots, salad and a small baked potato. Or g ...
CONFERENCE REPORT FROM A NOBEL MINISYMPOSIUM/JIM
... scientists as well researchers from biotech and pharmceutical companies. The topic The aim of this Minisymposium was to bring together researchers who work on amyloid in a broad perspective. This is motivated by recent discoveries showing that amyloid is intricately related not only to traditional a ...
... scientists as well researchers from biotech and pharmceutical companies. The topic The aim of this Minisymposium was to bring together researchers who work on amyloid in a broad perspective. This is motivated by recent discoveries showing that amyloid is intricately related not only to traditional a ...
Primary Structure of Diphtheria Toxin Fragment B
... Diphtheria toxin (62,000 daltons) is a typical example of the group of toxic proteins that use receptor-mediated internalization to reach their cytoplasmic targets (20). The proteolytically activated molecule consists of two functionally distinct fragments linked together by a disulfide bridge. The ...
... Diphtheria toxin (62,000 daltons) is a typical example of the group of toxic proteins that use receptor-mediated internalization to reach their cytoplasmic targets (20). The proteolytically activated molecule consists of two functionally distinct fragments linked together by a disulfide bridge. The ...
Serum Proteomic Fingerprints of Adult Patients with Severe Acute
... technology can identify serum proteins or protein fragments that are differentially regulated in adult SARS patients. To avoid identification of falsely significant differential proteomic features (16 ), we used a datamining strategy similar to that used in our previous studies (10, 13 ). We conside ...
... technology can identify serum proteins or protein fragments that are differentially regulated in adult SARS patients. To avoid identification of falsely significant differential proteomic features (16 ), we used a datamining strategy similar to that used in our previous studies (10, 13 ). We conside ...
pGADT7 AD Vector Information
... pGADT7 AD is the AD Cloning Vector provided in Clontech's Matchmaker™ Gold Yeast One- and Two-Hybrid Screening Systems (Cat. Nos. 630491 and 630489, respectively). The vector allows the generation of GAL4 AD fusion proteins from either a gene of interest or a cDNA library. Important: Genes must be c ...
... pGADT7 AD is the AD Cloning Vector provided in Clontech's Matchmaker™ Gold Yeast One- and Two-Hybrid Screening Systems (Cat. Nos. 630491 and 630489, respectively). The vector allows the generation of GAL4 AD fusion proteins from either a gene of interest or a cDNA library. Important: Genes must be c ...
Noni Juice - Healthoracle.org
... In rebuttal to Heinicke’s proxeronine theory McClatchey states that the evidence is outrageous and unreferenced claiming that there is no chemical structure given for the ‘alkaloid’ xeronine and no clear indication of the scientific research from which they are derived. This claim and the following ...
... In rebuttal to Heinicke’s proxeronine theory McClatchey states that the evidence is outrageous and unreferenced claiming that there is no chemical structure given for the ‘alkaloid’ xeronine and no clear indication of the scientific research from which they are derived. This claim and the following ...
Product_Cheluminate_100915
... The principle of the bicinchoninic acid (BCA) assay is similar to the Lowry procedure, in that both rely on the formation of a Cu2+-protein complex under alkaline condition followed by reduction of the Cu2+ to Cu1+. The amount of reduction is proportional to the protein present. In the second step, ...
... The principle of the bicinchoninic acid (BCA) assay is similar to the Lowry procedure, in that both rely on the formation of a Cu2+-protein complex under alkaline condition followed by reduction of the Cu2+ to Cu1+. The amount of reduction is proportional to the protein present. In the second step, ...
Using Mascot to characterise protein modifications
... The digestion of the H3 protein with Glu-C cleaved the protein to produce the 1-50 piece further isolated by off-line HPLC. A Chymotrypsin digestion of the 1-50 piece primarily produced peptide residues of 1-5, 1-19, 1-20, 6-19, 6-20, 20-39, 21-39, 2339, 24-39, 21-41, 40-50, 42-50 and other random p ...
... The digestion of the H3 protein with Glu-C cleaved the protein to produce the 1-50 piece further isolated by off-line HPLC. A Chymotrypsin digestion of the 1-50 piece primarily produced peptide residues of 1-5, 1-19, 1-20, 6-19, 6-20, 20-39, 21-39, 2339, 24-39, 21-41, 40-50, 42-50 and other random p ...
Title: Study of the interactions between Bovine Serum Albumin (BSA
... Albumins represent the major protein content in blood plasma. When drugs are introduced into human bodies albumins usually interact with them influencing the therapeutic process. The understanding of the interactions between albumins and drugs has become a very important research branch in pharmacok ...
... Albumins represent the major protein content in blood plasma. When drugs are introduced into human bodies albumins usually interact with them influencing the therapeutic process. The understanding of the interactions between albumins and drugs has become a very important research branch in pharmacok ...
Example 2 Monte Carlo Simulation
... Distance-based versus discrete methods • Distance methods first convert aligned sequences into a pair-wise distance matrix and then input the matrix into a tree building method • Discrete methods are based on characters i.e., consider each nucleotide or amino acid directly • In distance methods, on ...
... Distance-based versus discrete methods • Distance methods first convert aligned sequences into a pair-wise distance matrix and then input the matrix into a tree building method • Discrete methods are based on characters i.e., consider each nucleotide or amino acid directly • In distance methods, on ...
Essential Bioinformatics and Biocomputing
... • We would avoid conclusions like this by looking at the similarity scores. This will be done in more detail later in the course, for now it is important to know that the lower the expected value, the better the match. Anything close or greater than 1 should be observed with suspicion. However, some ...
... • We would avoid conclusions like this by looking at the similarity scores. This will be done in more detail later in the course, for now it is important to know that the lower the expected value, the better the match. Anything close or greater than 1 should be observed with suspicion. However, some ...
GFP (Green fluorescent protein)
... to look directly into the inner workings of cells. It is easy to find out where GFP is at any given time: you just have to shine ultraviolet light, and any GFP will glow bright green. So here is the trick: you attach the GFP to any object that you are interested in watching. For instance, you can at ...
... to look directly into the inner workings of cells. It is easy to find out where GFP is at any given time: you just have to shine ultraviolet light, and any GFP will glow bright green. So here is the trick: you attach the GFP to any object that you are interested in watching. For instance, you can at ...
Synaptic adhesion molecules - UCSF Physiology
... with five Ig-like domains, two FNIII domains and a cytoplasmic domain with a C-terminal PDZ domain-binding motif. Dasm has been shown to promote dendritic elongation and branching as well as the maturation of excitatory glutamatergic synapses. Dasm interacts with PDZ-containing scaffold proteins, i ...
... with five Ig-like domains, two FNIII domains and a cytoplasmic domain with a C-terminal PDZ domain-binding motif. Dasm has been shown to promote dendritic elongation and branching as well as the maturation of excitatory glutamatergic synapses. Dasm interacts with PDZ-containing scaffold proteins, i ...
Receptor 接受器or受器
... -also called receptor tyrosine kinases OR ligand-triggered protein kinases -similar to tyrosine-linked receptors - ligand binding results in formation of a dimer -BUT: they differ from tyrosine-linked receptors – intrinsic catalytic activity -means that ligand binding activates it and the activated ...
... -also called receptor tyrosine kinases OR ligand-triggered protein kinases -similar to tyrosine-linked receptors - ligand binding results in formation of a dimer -BUT: they differ from tyrosine-linked receptors – intrinsic catalytic activity -means that ligand binding activates it and the activated ...
Comparative Modeling of Mainly
... Packing moves earlier in the modeling process • In order to produce more accurate sequence-structure alignments, we return several possible “wraps” and try to pack sidechains. • So sidechain packing is used earlier in the comparative modeling process; also to help find the correct sequence-structur ...
... Packing moves earlier in the modeling process • In order to produce more accurate sequence-structure alignments, we return several possible “wraps” and try to pack sidechains. • So sidechain packing is used earlier in the comparative modeling process; also to help find the correct sequence-structur ...
Development of antifertility vaccine using sperm specific proteins
... Sperm proteins are known to be associated with normal fertilization as auto- or iso-antibodies to these proteins may cause infertility. Therefore, sperm proteins have been considered to be the potential candidate for the development of antifertility vaccine. Some of the sperm proteins proved to be p ...
... Sperm proteins are known to be associated with normal fertilization as auto- or iso-antibodies to these proteins may cause infertility. Therefore, sperm proteins have been considered to be the potential candidate for the development of antifertility vaccine. Some of the sperm proteins proved to be p ...
proposal-aug25
... likely to have biological functions. To confirm that the short conserved segments are indeed short linear motifs, we have searched for conserved segments that match known short linear motifs. For example, the FG motif is found in disordered regions of nuclear pore complex (NPC) proteins [67]. Of the ...
... likely to have biological functions. To confirm that the short conserved segments are indeed short linear motifs, we have searched for conserved segments that match known short linear motifs. For example, the FG motif is found in disordered regions of nuclear pore complex (NPC) proteins [67]. Of the ...
Making sense of Sequences: Comparative Genomics and the New GIS
... Another Genomic Revolution An explosion in genomic data The rise of population genomics & proteomics ...
... Another Genomic Revolution An explosion in genomic data The rise of population genomics & proteomics ...
ERNDIM - Quantitative Schemes Cystine in White Blood Cells
... Short-term reports on the eight individual specimens are available two weeks after the submission deadline and provide up-to-date information on analytical performance. Although technically reports could be immediately available a delay time of 14 days has been introduced to enable the scientific a ...
... Short-term reports on the eight individual specimens are available two weeks after the submission deadline and provide up-to-date information on analytical performance. Although technically reports could be immediately available a delay time of 14 days has been introduced to enable the scientific a ...
Presentation @3:30pm - Bioinformatics at School of Informatics
... i.e. an amino acid is denoted as either modified or unmodified. In reality, some amino acids are modified under one condition, and return to their initial state when the condition changes. The status of a specific amino acid site with respect to a modification is highly associated with biological fu ...
... i.e. an amino acid is denoted as either modified or unmodified. In reality, some amino acids are modified under one condition, and return to their initial state when the condition changes. The status of a specific amino acid site with respect to a modification is highly associated with biological fu ...
Proteomics
Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term proteomics was first coined in 1997 to make an analogy with genomics, the study of the genome. The word proteome is a portmanteau of protein and genome, and was coined by Marc Wilkins in 1994 while working on the concept as a PhD student.The proteome is the entire set of proteins, produced or modified by an organism or system. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain formed on the basis of the research and development of the Human Genome Project; it is also emerging scientific research and exploration of proteomes from the overall level of intracellular protein composition, structure, and its own unique activity patterns. It is an important component of functional genomics.While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry.