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Slides - Department of Computer Science • NJIT
Slides - Department of Computer Science • NJIT

... • Since A (adenosine) always pairs with T (thymine) and C (cytosine) always pairs with G (guanine) knowing only one side of the ladder is enough • We represent DNA as a sequence of letters where each letter could be A,C,G, or T. • For example, for the helix shown here we would represent this as CAGT ...
CHM 103 Lecture 36 S07
CHM 103 Lecture 36 S07

... Example: Globular Proteins • have compact, spherical shapes. • carry out synthesis, transport, and metabolism in the cells. • such as myoglobin store and transport oxygen in muscle. Myoglobin ...
TDH - an Enzyme Involved in Metabolising Threonine to Glycine
TDH - an Enzyme Involved in Metabolising Threonine to Glycine

... The data were processed using programs in the CCP4 suite, however the predicted spacegroup was ambiguous and took time to determine correctly. P4 was found to generate the best predictions in MOSFLM and the data was subsequently processed and scaled, giving an Rmerge of 0.154. It was later processed ...
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Class details

... Manual: Details of Beer-Lambert’s law ...
Molecular Principles of Bioactive Systems
Molecular Principles of Bioactive Systems

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CHAPTER 14 Vesicular Traffic, Secretion, and Endocytosis
CHAPTER 14 Vesicular Traffic, Secretion, and Endocytosis

... triggered by Sec12 → induced catalyzes the GDP for GTP of Sar1 → binding Sar1 to ER membrane → followed by binding of Sec13/24 → formation of ...
PROTEINS:
PROTEINS:

... In the solid state amino acids exist entirely in the dipolar form callled zwitterion. Amino acids are internally neutralized molecule. Since amino acids has its own proton donating group, NH3+and has its own proton accepting group, COO- so these dipolar ions can neutralize acids or bases of sufficie ...
Molecules of life
Molecules of life

... formed at each bond ...
Leukaemia Section t(6;9)(p23;q34) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(6;9)(p23;q34) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... Contains acidic domains and a nuclear localisation signal; DNA binding protein; transcriptional regulation and signal transduction. ...
Variations in Surface Protein Composition Associated
Variations in Surface Protein Composition Associated

... membrane composition. Nevertheless, differences occur between the variants in properties which directly affect potential virulence and appear to be correlated with particular outer membrane proteins. Gonococci present in urethral exudates (Ward et al., 1970) and infected subcutaneous chambers in gui ...
Transport to the vacuole: receptors and trans elements
Transport to the vacuole: receptors and trans elements

... (Leborgne and Hoflack, 1997). By analogy, it was reasoned that a receptor for the targeting determinants for vacuolar delivery in plants would also be present in CCVs. This contention was consistent with an earlier observation that CCVs from developing pea cotyledon contained acid hydrolases (Harley ...
4.1_Proteins_Amino_Acids_2011
4.1_Proteins_Amino_Acids_2011

... . Steric limitations on the bond angles in a polypeptide chain (A) Each amino acid contributes three bonds (red) to the backbone of the chain. The peptide bond is planar (gray shading) and does not permit rotation. By contrast, rotation can occur about the Cα–C bond, whose angle of rotation is calle ...
Biochemistry PowerPoint 1
Biochemistry PowerPoint 1

... • More than 20 amino acids can be joined in any order or number to make countless proteins (think of how many words can be made from 26 letters!) ...
Correlating mRNA and protein Abundance
Correlating mRNA and protein Abundance

... ICAT vs microarray N ~ 290, r = 0.6 ...
N - KIAS
N - KIAS

... How does a chain (necklace with different shape pearls) fold up and how ...
Mid Term Solutions - Department of Chemistry ::: CALTECH
Mid Term Solutions - Department of Chemistry ::: CALTECH

... There are some other secondary structures such as 310 helix and π helix, however, they are not very common and are not haracterizedas most common and favorable hydrogen bonding patterns in natural proteins. Amino acids vary in their ability to form the various secondary structure elements. Proline a ...
Surface expression of the conserved ribosomal protein P0 on
Surface expression of the conserved ribosomal protein P0 on

... cell staining (Fig. 2E). The epithelial cell line SCC also showed surface staining (Fig. 2E, d). The frequency of cells staining for these cell lines was low, varied with cell lines, and with different experiments, but was always within 2–5%. For each cell type, SIFA experiments were performed at le ...
Proteins - Winona State University
Proteins - Winona State University

... Incomplete proteins are low in one or more essential amino acid ( e.g. most plant proteins) This can create problems for people on vegetarian or vegan diets, or for people on special diets low in meats, milk, eggs, etc. ...
Proteins
Proteins

... • All protein Contain C, H, O, N, and most contain sulfur, some contain phosphorus and a few have mineral elements such as Fe, Mg and Cu. • Serve as structural components of animals. • Proteins are polymers consisting of 20 kinds of amino acids. ...
Discovering patterns to extract protein–protein interactions from full
Discovering patterns to extract protein–protein interactions from full

... is based on simple rules. It is able to handle long sentences and achieves high performances with a recall rate of 85% and precision rate of 94% for yeast and Escherichia coli. However, manually writing patterns for every verb is not practical for general purpose applications. In GENIES, more compli ...
Lecture 9: Biological Pathway Simulation
Lecture 9: Biological Pathway Simulation

... Signal = LIGAND Ligand- A molecule that binds to a specific site on another molecule, usually a protein, ie receptor ...
Dr Gisela Storz Biosketch
Dr Gisela Storz Biosketch

... Development  in  Bethesda,  where  she  is  a  Senior  Investigator.    Dr.   Storz  has  made  contributions  in  multiple  fields  of  molecular  biology,   including  groundbreaking  experiments  on  the  sensing  of  oxidative   stress ...
Animal cell culture lecture -3
Animal cell culture lecture -3

... • The collagens are a large family of proteins containing at least 27 different members ...
1. Given the molecule: a. What type of molecule is this? b. Give the
1. Given the molecule: a. What type of molecule is this? b. Give the

... shown to the right. Would you expect the pKa of pyruvate’s carboxyl group to differ from that of the molecule above? If yes, which pKa would be lower and why? If no, why wouldn’t they differ? (Explain in 40 words or fewer.) ...
KTH | BB2160 Structure Biology 7.5 credits
KTH | BB2160 Structure Biology 7.5 credits

... You should be able to describe the main characteristics of amino acids and the principle types of motifs and folds. You should know about the principle forces that fold the proteins and maintain the structures, and be able to suggest changes to a protein structure that would lead to for instance inc ...
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Protein–protein interaction



Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.
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