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Diapositiva 1
Diapositiva 1

... Androgen receptor (AR) is a hormone-activated transcription factor that plays important roles in prostate development and function, as well as malignant transformation. AR has been primarily known as a transcriptional activator inducing prostate-specific gene expression. AR as a globally acting tran ...
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Mitosis and Asexual Reproduction
Mitosis and Asexual Reproduction

... Eukaryotic: a domain of organisms having cells each with a distinct nucleus within which the genetic material is contained along with other membrane-bound organelles. Prokaryotic: any organism having cells in each of which the genetic material is in a single DNA chain, not enclosed in a nucleus. The ...
Control of Gene Express in Prokaryotes
Control of Gene Express in Prokaryotes

... structural genes, located between the promoter and structural genes, contains the operator site. • Operator Site -region where the repressor attaches • Regulatory genes-codes for repressor proteins • Polycistronic mRNA-transcript for several polypeptides ...
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Next Generation Genomic Sequence Identification of the 19q
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... People who have one dominant allele and one recessive, disorder-causing allele, do not have the disorder, but can pass it on because they are carriers of the disorder. • Sex-linked genes: Genes on the sex-chromosomes (the X and Y chromosomes in many species) are sex-linked genes. In mammals, includi ...
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... - GM white blood cells that produce proteins that kill cancer cells - targeting genes at cancer cells to kill them or revert them back to normal cells - white blood cells that would not reproduce if infected with HIV - germ-line modification (only present in animals) which is currently illegal - at ...


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... I. A New View of Mendelian Genetics A. Rarely is a trait controlled by a single gene. 1. Genes interact with each other and the environment. 2. Mendel’s laws are still in effect. II. When Gene Expression Appears to Alter Mendelian Ratios A. Gene Expression 1. The __________ change when some traits s ...
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... How is the “open” architecture of the nucleus maintained and controlled under the osmotic pressure of de-condensed, active DNA sections. Equation of State of DNA bundles is known. Dynamics: Chromosome dynamics driven by DNA condensation/de-condensation events triggered by local gene expression:”gene ...
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Polycomb Group Proteins and Cancer

The Polycomb-group proteins (PcGs) are a family of proteins that use epigenetic mechanisms to maintain or repress expression of their target genes. They were originally discovered in Drosophila (fruit flies), though they've been shown to be conserved in many species due to their vital roles in embryonic development. These proteins' ability to alter gene expression has made them targets of investigation for research groups seeking to understand disease pathology and oncology.
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