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28/03 - Instituto de Psicologia da USP
28/03 - Instituto de Psicologia da USP

... Sarnyai, Z., & Kovacs, G. L. (1994). Role of oxytocin in the neuroadaptation to drugs of abuse. Psychoneuroendocrinology, 19, 85-117. RESUMO: Oxytocin (OXT), a neurohypophyseal hormone, has a wide range of behavioral effects outside its classic peripheral endocrine functions. OXT involvement in adap ...
Why are Drug Addicts Compelled to Risk Their Lives for Something
Why are Drug Addicts Compelled to Risk Their Lives for Something

... allows a person to feel pleasure.  Meth raises this chemical abnormally.  Crystal meth raises dopamine levels over 10 times more than regular pleasures of life.  Meth creates an extreme rush of pleasure which plays a large role in the addiction to meth. ...
Addiction Treatment: A Strengths Perspective 3rd Edition
Addiction Treatment: A Strengths Perspective 3rd Edition

... Some emphasis on gender-sensitive treatment. Class and cultural differences in drug use. Male/female ratios differ in drinking quantity ratios from 13:12 in Italy to 28:11 in Canada, 46:5 in Mexico, and 15:3 in Russia. In American high schools, substance use rates about the same. Adult men, twice th ...
Grant
Grant

...  Compulsivity = repetitive behaviors with the goal of reducing/preventing anxiety or distress, not for pleasure or gratification  May occur simultaneously or at different times within the same disorder ...
SNPs as Co-morbid Factors for Drug Abuse and Ischemic Heart
SNPs as Co-morbid Factors for Drug Abuse and Ischemic Heart

... may be influenced by multiple polymorphisms of multiple genes. Whether vulnerability to drug abuse is enhanced or reduced by a general set of genetic variables, and, also whether there is a specific subset of polymorphisms for each drug of abuse or a combination of these has not yet been fully eluci ...
Chapter Overview
Chapter Overview

... Recently some states have moved to not only decriminalize but actually legalize the possession and use of small amounts of marijuana. Do you support this movement? Why or why not? Can you think of some unintended consequences of such policy changes? Hallucinogen-Related Disorders What are the physio ...
The Brain and Addition
The Brain and Addition

... a hot day—that's your limbic system at work. Because natural pleasures in our lives are necessary for survival, the limbic system creates an appetite that drives you to seek those things. ...
Chapter Overview/Summary
Chapter Overview/Summary

... Several psychoses related to alcoholism have been identified: idiosyncratic intoxication, withdrawal delirium, chronic alcoholic hallucinosis, and dementia associated with alcoholism. Drug abuse disorders may involve physiological dependence on substances, such as opiates – particularly heroin–or ba ...
Neurobiology of food addiction
Neurobiology of food addiction

... different serotonergic receptors subtypes in the NAc of living rats resulted in distinct changes in the rats’ feeding behaviors. For example, although intra-NAc infusion of a 5-hydroxytryptamine (5-HT) 1/7 receptor agonist led to a dose-dependent reduction in rats’ consumption of both laboratory cho ...
Dual Diagnosis: Mental Illness And Substance Abuse
Dual Diagnosis: Mental Illness And Substance Abuse

... disorder. Dual diagnosis is sometime referred to as co-occurring disorders or comorbidity. The term “comorbidity” describes two or more disorders occurring in the same person. They can occur at the same time or one after the other. Comorbidity also implies interactions between the illnesses that can ...
NSDUH The Report 10.8 Million Full-Time Workers
NSDUH The Report 10.8 Million Full-Time Workers

... difficult and cause employees to miss work or be injured on the job.1 According to combined 2008 to 2012 National Survey on Drug Use and Health (NSDUH) data, adults aged 18 to 64 who were unemployed were more likely than those in other employment groups to have had a past year substance use disorder ...
PPT - The Citadel
PPT - The Citadel

... intoxication detrimental to the individual and society, which is characterized by an overwhelming desire to continue taking the drug and to obtain it by any means”  Addiction is a complex disease. ...
Access #: 517302 - Riverside County Drug Endangered Children
Access #: 517302 - Riverside County Drug Endangered Children

... "If I hadn't quit, I would have ended up in a mental ward." Prescription drugs stabilize his mood swings, but the Valley College student says he still has little ability to concentrate and must read a page four or five times to comprehend and remember it. "I go through days with no concentration, so ...
CNS Spectrums, in press 2016 Opinion Piece: Expanding the
CNS Spectrums, in press 2016 Opinion Piece: Expanding the

... substance addictions; gambling often decreases anxiety and results in a positive mood state or “high”, similar to substance intoxication; and emotional dysregulation often contributes to gambling cravings just as with alcohol or drug cravings. In addition, there are unusually high rates of co-occurr ...
Psychoactive substance use disorders
Psychoactive substance use disorders

... Psychoactive substance use disorders Dr. Bodrogi Andrea ...
1) Pure cocaine was first extracted from the coca bush in the
1) Pure cocaine was first extracted from the coca bush in the

... Cocaine Abuse and Addiction 1) Pure cocaine was first extracted from the coca bush in the a) early 19th century b) mid 19th century c) early 20th century d) mid 20th century 2) In 2002, an estimated _____ Americans could be classified as dependent on or abusing cocaine in the past 12 months. a) 1.5 ...
Mouse Party - Teach Genetics (Utah)
Mouse Party - Teach Genetics (Utah)

... out of the cell into the synapse. The serotonin becomes trapped in the synapse, repeatedly binding to receptors and exciting the cell. Binds to cannabinoid receptors and turns off the release of inhibitory neurotransmitters. Excess dopamine floods the synapse. ...
Amino Acid - AsheraHart.net
Amino Acid - AsheraHart.net

... neurotransmitters and the reward cascade in a single supplement for easier use and less guesswork. Blum’s most recent formulation is called REWARD (distributed by Nutrigenomics in Pittsburg, California.) It is known that if someone carries the dopamine D2 A1 gene variant (and possibly other gene var ...
Internet Addiction
Internet Addiction

... to addictive syndromes similar to impulsecontrol disorders on the Axis 1 Scale in the DSM-IV-TR. Like these impulse-control disorders,(such as, intermittent explosive disorder, pathological gambling, and ...
Be a Part of the Conversation
Be a Part of the Conversation

... Opioid pain relievers attach to the same cell receptors targeted by illegal opioids like heroin. Opioids can produce drowsiness, cause constipation, and—depending upon the amount taken—depress breathing. The latter effect makes opioids particularly dangerous, especially when they are snorted or inje ...
Drugs and Addiction
Drugs and Addiction

... C)  Investigating  the  effect  of  CNS  stimulants:    (Alternate  protocol  for  drug  investigation  in  section  E)   1.  Using  a  pipette,  add  one  drop  of  the  diluted  CNS  stimulant  chemical  (adrenalin)  to  the  ring   ...
MEDICATION ASSISTED TREATMENT - PRESCRIPTION DRUG AND OPIOID ADDICTION (MAT-PDOA) PROGRAM Background
MEDICATION ASSISTED TREATMENT - PRESCRIPTION DRUG AND OPIOID ADDICTION (MAT-PDOA) PROGRAM Background

... The misuse of and addiction to licit and illicit opioids is a serious and challenging public health problem. In 2010, licit and illicit drug overdoses killed more people than traffic accidents, guns, and falls with 38,329 overall deaths, 30,006 of which were unintentional. 1 On average, 105 people d ...
lessonthreepp_9-16
lessonthreepp_9-16

... What genes are included in the smoking behavior study? • Two regions in the dopamine receptor gene (DRD2), which codes for a protein that binds dopamine, found on the dendrites of receiving neurons • One region in the dopa decarboxylase gene (DDC), which codes for a protein involved in dopamine syn ...
What are drugs? - Lakehurst School District
What are drugs? - Lakehurst School District

... today’s world, you hear a lot about drugs. You hear about all kinds of drugs from drugs that are used to treat diseases and save lives to illegal drugs that can cause many problems. But what is a drug? ...
nicotine / neuroimaging 2006
nicotine / neuroimaging 2006

... The study was conducted at the Hoglund Brain Imaging Center of the University of Kansas Medical Center in Kansas City, KS. We studied 17 smokers (eight AA, nine CC) after 12-hour abstinence and 17 non-smokers (eight AA, nine CC) matched by age, gender, years of education, and handedness. The AA and ...
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Addiction

Addiction is a state characterized by compulsive engagement in rewarding stimuli, despite adverse consequences. It can be thought of as a disease or biological process leading to such behaviors. The two properties that characterize all addictive stimuli are that they are reinforcing (i.e., they increase the likelihood that a person will seek repeated exposure to them) and intrinsically rewarding (i.e., something perceived as being positive or desirable).Addiction is a disorder of the brain's reward system which arises through transcriptional and epigenetic mechanisms and occurs over time from chronically high levels of exposure to an addictive stimulus (e.g., morphine, cocaine, sexual intercourse, gambling, etc.). ΔFosB, a gene transcription factor, is a critical component and common factor in the development of virtually all forms of behavioral and drug addictions; two decades of research into ΔFosB's role in addiction have demonstrated that addiction arises, and addictive behavior intensifies or attenuates, along with the genetic overexpression of ΔFosB in the D1-type medium spiny neurons of the nucleus accumbens; due to the causal relationship between ΔFosB expression and addictions, it is used preclinically as an addiction biomarker. ΔFosB expression in these neurons directly and positively regulates drug self-administration and reward sensitization through positive reinforcement, while decreasing sensitivity to aversion.Addiction exacts an astoundingly high toll on individuals and society as a whole through the direct adverse effects of drugs, associated healthcare costs, long-term complications (e.g., lung cancer with smoking tobacco, liver cirrhosis with drinking alcohol, or meth mouth from intravenous methamphetamine), the functional consequences of altered neural plasticity in the brain, and the consequent loss of productivity. Classic hallmarks of addiction include impaired control over substances or behavior, preoccupation with substance or behavior, and continued use despite consequences. Habits and patterns associated with addiction are typically characterized by immediate gratification (short-term reward), coupled with delayed deleterious effects (long-term costs).Examples of drug and behavioral addictions include: alcoholism, amphetamine addiction, cocaine addiction, nicotine addiction, opiate addiction, exercise addiction, food addiction, gambling addiction, and sexual addiction. The term addiction is misused frequently to refer to other compulsive behaviors or disorders, particularly dependence, in news media.
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