- Boehringer Ingelheim (Canada)
... Patients with Congestive Heart Failure: A limited number of patients with history of congestive heart failure participated in clinical studies with TRAJENTA. In clinical trials, patients with a clinically significant history of cardiac disease or presence of active cardiac disease within 6 months we ...
... Patients with Congestive Heart Failure: A limited number of patients with history of congestive heart failure participated in clinical studies with TRAJENTA. In clinical trials, patients with a clinically significant history of cardiac disease or presence of active cardiac disease within 6 months we ...
SW_QA257.4_LMWH_in_renal_impairment _PROPHYLAXIS _Final
... A small prospective study was conducted to analyse the influence of renal function on anti-Xa levels in 125 acutely ill medical patients receiving enoxaparin 40mg daily (21). Anti-Xa levels were measured in 58 patients and on days 4 to 10 these were significantly higher than levels taken on days 1 t ...
... A small prospective study was conducted to analyse the influence of renal function on anti-Xa levels in 125 acutely ill medical patients receiving enoxaparin 40mg daily (21). Anti-Xa levels were measured in 58 patients and on days 4 to 10 these were significantly higher than levels taken on days 1 t ...
Monitoring of Liver Function Tests in Patients - PCSS-MAT
... HIV-infected and 90% was HCV-infected; however, patients with transaminase levels greater than 3-times ULN were not enrolled. A total of 40 (32%) of the placebo group experienced >1 adverse event (AE) compared to N=63 (50%) of the XR-NTX group; N=4 (3%) of the placebo and N=3 (2%) of the XR-NTX grou ...
... HIV-infected and 90% was HCV-infected; however, patients with transaminase levels greater than 3-times ULN were not enrolled. A total of 40 (32%) of the placebo group experienced >1 adverse event (AE) compared to N=63 (50%) of the XR-NTX group; N=4 (3%) of the placebo and N=3 (2%) of the XR-NTX grou ...
Tarceva - Genentech
... function; the risk of hepatic toxicity is increased in patients with baseline hepatic impairment. In clinical studies where patients with moderate to severe hepatic impairment were excluded, the pooled incidence of hepatic failure in the 3 monotherapy lung cancer studies was 0.4% in the TARCEVA arms ...
... function; the risk of hepatic toxicity is increased in patients with baseline hepatic impairment. In clinical studies where patients with moderate to severe hepatic impairment were excluded, the pooled incidence of hepatic failure in the 3 monotherapy lung cancer studies was 0.4% in the TARCEVA arms ...
- ScholarWorks @ UVM
... United States between 1996-2010 alone.1 Moreover, intranasal naloxone has proven an equally effective route of drug administration when compared to IV dosing in emergent prehospital settings2, and retrospective studies have shown no significant difference in efficacy between doses delivered by healt ...
... United States between 1996-2010 alone.1 Moreover, intranasal naloxone has proven an equally effective route of drug administration when compared to IV dosing in emergent prehospital settings2, and retrospective studies have shown no significant difference in efficacy between doses delivered by healt ...
Handout to Beta blocker therapy in heart failure in the elderly
... iii. Defined as LVEF ≥50% (however further research is needed to characterize these patients) 1. Other definitions a. HFpEF borderline (LVEF 41-48%) b. HFpEF improved (LVEF >40%) i. Patients with HFpEF who previously had HFrEF c. Patient characteristics, treatments, and outcomes are similar to those ...
... iii. Defined as LVEF ≥50% (however further research is needed to characterize these patients) 1. Other definitions a. HFpEF borderline (LVEF 41-48%) b. HFpEF improved (LVEF >40%) i. Patients with HFpEF who previously had HFrEF c. Patient characteristics, treatments, and outcomes are similar to those ...
rowasa - Meda Pharmaceuticals
... rarely been reported among patients treated with mesalamine. Pregnancy (Category B) Teratologic studies have been performed in rats and rabbits at oral doses up to five and eight times respectively, the maximum recommended human dose, and have revealed no evidence of harm to the embryo or the fetus. ...
... rarely been reported among patients treated with mesalamine. Pregnancy (Category B) Teratologic studies have been performed in rats and rabbits at oral doses up to five and eight times respectively, the maximum recommended human dose, and have revealed no evidence of harm to the embryo or the fetus. ...
Pediatric Dosage Calculations
... Care must be taken to properly convert body weight from pounds to kilograms (1 kg= 2.2 lb) before calculating doses based on body weight. Doses are often expressed as mg/kg/day or mg/kg/dose, therefore orders written "mg/kg/d" which is confusing, require further clarification from the prescriber. Ch ...
... Care must be taken to properly convert body weight from pounds to kilograms (1 kg= 2.2 lb) before calculating doses based on body weight. Doses are often expressed as mg/kg/day or mg/kg/dose, therefore orders written "mg/kg/d" which is confusing, require further clarification from the prescriber. Ch ...
Filariasis: diagnosis, treatment and prevention
... blood and are due to their rapid destruction which is characterized by fever, headache, myalgia, sore throat or cough lasting for 24 to 48 hours (10). They are usually mild and self-limiting requiring only symptomatic treatment. Direct adverse effects related to the drug are very rare. Recent trials ...
... blood and are due to their rapid destruction which is characterized by fever, headache, myalgia, sore throat or cough lasting for 24 to 48 hours (10). They are usually mild and self-limiting requiring only symptomatic treatment. Direct adverse effects related to the drug are very rare. Recent trials ...
Pegicol™ – Oral treatment for chronic constipation and faecal
... and electrolytes. Polyethylene glycol exerts its laxative effect by virtue of its osmotic effect in the gut. Water is kept in the lumen, which softens stools and promotes bowel movement. The electrolytes contained in the formulation ensure that there is virtually no net gain or net loss of sodium, p ...
... and electrolytes. Polyethylene glycol exerts its laxative effect by virtue of its osmotic effect in the gut. Water is kept in the lumen, which softens stools and promotes bowel movement. The electrolytes contained in the formulation ensure that there is virtually no net gain or net loss of sodium, p ...
It`s time to set the story straight
... anti-inflammatory drugs (NANSAIDs) and serious upper gastrointestinal bleeding: a meta-analysis based on individual patient data. Br J Clin Pharmacol. 2002;54(3):320-326. 7. McGettigan P, Henry D. Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based c ...
... anti-inflammatory drugs (NANSAIDs) and serious upper gastrointestinal bleeding: a meta-analysis based on individual patient data. Br J Clin Pharmacol. 2002;54(3):320-326. 7. McGettigan P, Henry D. Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based c ...
Cutaneous Side Effects in Non-Small Cell Lung Cancer Patients
... metastatic and advanced NSCLC (stage IV) not curable with standard therapy. The patients had received prior cancer therapies, including chemotherapy and radiotherapy. They were excluded if they showed evidence of another severe or uncontrolled systemic disease, unresolved toxicity from previous anti ...
... metastatic and advanced NSCLC (stage IV) not curable with standard therapy. The patients had received prior cancer therapies, including chemotherapy and radiotherapy. They were excluded if they showed evidence of another severe or uncontrolled systemic disease, unresolved toxicity from previous anti ...
$doc.title
... to a nursing woman because many drugs are excreted in human milk. Pregnancy Use This efficacy supplement has no new information on pregnant women. Ondansetron is currently listed as Pregnancy Category B. Reproduction studies have been performed in pregnant rats and rabbits at I.V. doses up to 4 mg/k ...
... to a nursing woman because many drugs are excreted in human milk. Pregnancy Use This efficacy supplement has no new information on pregnant women. Ondansetron is currently listed as Pregnancy Category B. Reproduction studies have been performed in pregnant rats and rabbits at I.V. doses up to 4 mg/k ...
Antipsychotic Use in Children and Adolescents: Minimizing Adverse Effects to Maximize Outcomes
... treatment. In another, more recent study, however, 0 of 38 patients developed withdrawal dyskinesia after risperidone (mean dose 2 mg/day) was discontinued after 4 months of treatment (21). The risk for withdrawal dyskinesia can be reduced with slow cross-titration and overlapping cross-titration (5 ...
... treatment. In another, more recent study, however, 0 of 38 patients developed withdrawal dyskinesia after risperidone (mean dose 2 mg/day) was discontinued after 4 months of treatment (21). The risk for withdrawal dyskinesia can be reduced with slow cross-titration and overlapping cross-titration (5 ...
Popular Links
... when switching to methadone. When switching to methadone, the starting dose should be 10% to 25% of the equianalgesic dose. Opioid dose should then be titrated and individualized to clinical situation and patient response. When using higher total doses, decrease total dose incrementally by 30% per d ...
... when switching to methadone. When switching to methadone, the starting dose should be 10% to 25% of the equianalgesic dose. Opioid dose should then be titrated and individualized to clinical situation and patient response. When using higher total doses, decrease total dose incrementally by 30% per d ...
Hepatoprotective potential of Cordia subcordata Lam. against
... Aim: To investigate the phytoconstituents, acute oral toxicity and hepatoprotective activity of ethanol (90%) extract of Cordia subcordata Lam. (EECS) using CCl4 induced hepatotoxicity in male Wistar albino rats. Methods: The EECS at doses of 100, 200 and 400mg/kg, p.o and the standard drug Liv.52 ( ...
... Aim: To investigate the phytoconstituents, acute oral toxicity and hepatoprotective activity of ethanol (90%) extract of Cordia subcordata Lam. (EECS) using CCl4 induced hepatotoxicity in male Wistar albino rats. Methods: The EECS at doses of 100, 200 and 400mg/kg, p.o and the standard drug Liv.52 ( ...
Bulletin #88
... For treatment of migraines where standard therapy such as an analgesic has failed or cannot be tolerated. naratriptan HCl, tablet, 1mg, 2.5mg (Amerge-GSK) For treatment of migraine headaches where other standard therapy such as an analgesic has failed. Eligibility will be restricted to beneficiaries ...
... For treatment of migraines where standard therapy such as an analgesic has failed or cannot be tolerated. naratriptan HCl, tablet, 1mg, 2.5mg (Amerge-GSK) For treatment of migraine headaches where other standard therapy such as an analgesic has failed. Eligibility will be restricted to beneficiaries ...
11SUN Handouts.indd - The Collaborative Education Institute
... Many users report flu-like symptoms when coming down from a high very soon after the effects of the substance have worn off Cocaine is thought to be responsible for a quarter of all heart attacks in people under the age of 45. Cardiac effects from cocaine usually occur 48 hours after the last use. C ...
... Many users report flu-like symptoms when coming down from a high very soon after the effects of the substance have worn off Cocaine is thought to be responsible for a quarter of all heart attacks in people under the age of 45. Cardiac effects from cocaine usually occur 48 hours after the last use. C ...
Antiemetic drugs
... • Vomiting due to motion sickness • Vomiting of pregnancy • Vertigo Adverse effects: • Sedation (excitation may occur in children). • Atropine-like actions • Hypotension (block alpha1) ...
... • Vomiting due to motion sickness • Vomiting of pregnancy • Vertigo Adverse effects: • Sedation (excitation may occur in children). • Atropine-like actions • Hypotension (block alpha1) ...
Adverse reaction to Amoxicillin: a case report
... of their less cumulative exposure to antibiotics.3,8,26,27 About 25% of children with at least one parent who is allergic to an antibiotic may be at risk for development of allergy compared to 2% when neither parent has a drug allergy.18,22 Topical application is the most likely to elicit sensitizat ...
... of their less cumulative exposure to antibiotics.3,8,26,27 About 25% of children with at least one parent who is allergic to an antibiotic may be at risk for development of allergy compared to 2% when neither parent has a drug allergy.18,22 Topical application is the most likely to elicit sensitizat ...
Introduction
... COPD.11,20 Although it is a long-acting drug, systemic effects with formoterol are as short as salbutamol.10 Relatively, hydrophilic drugs such as salbutamol have rapid onset of action due to their ability to reach the β2 receptor from the aqueous phase.21 Formoterol is a moderately lipophilic drug ...
... COPD.11,20 Although it is a long-acting drug, systemic effects with formoterol are as short as salbutamol.10 Relatively, hydrophilic drugs such as salbutamol have rapid onset of action due to their ability to reach the β2 receptor from the aqueous phase.21 Formoterol is a moderately lipophilic drug ...
zycortal - Dechra Veterinary Products
... water absorption from the renal tubules resulting in increased extracellular fluid volume, leading to blood volume expansion, improved venous return to the heart, and increased cardiac output. After subcutaneous administration of 11 mg/kg body weight (five times the labeled starting/initial dose of ...
... water absorption from the renal tubules resulting in increased extracellular fluid volume, leading to blood volume expansion, improved venous return to the heart, and increased cardiac output. After subcutaneous administration of 11 mg/kg body weight (five times the labeled starting/initial dose of ...
zycortal - Dechra Veterinary Products
... water absorption from the renal tubules resulting in increased extracellular fluid volume, leading to blood volume expansion, improved venous return to the heart, and increased cardiac output. After subcutaneous administration of 11 mg/kg body weight (five times the labeled starting/initial dose of ...
... water absorption from the renal tubules resulting in increased extracellular fluid volume, leading to blood volume expansion, improved venous return to the heart, and increased cardiac output. After subcutaneous administration of 11 mg/kg body weight (five times the labeled starting/initial dose of ...
Read the updated advice - Association of Paediatric Anaesthetists
... 1. A history of prior experience with codeine should be sought, including: efficacy, side effects and family history of adverse events. If opioids have been used within the hospital setting before discharge ...
... 1. A history of prior experience with codeine should be sought, including: efficacy, side effects and family history of adverse events. If opioids have been used within the hospital setting before discharge ...
guidelines for the use of atypical antipsychotics
... All patients with symptoms of tardive dyskinesia. While atypical antipsychotics may pose a lower risk of causing tardive dyskinesia than conventional antipsychotics, long-term data with these newer agents are still limited. Therefore, the use of these agents should be limited to patients in whom t ...
... All patients with symptoms of tardive dyskinesia. While atypical antipsychotics may pose a lower risk of causing tardive dyskinesia than conventional antipsychotics, long-term data with these newer agents are still limited. Therefore, the use of these agents should be limited to patients in whom t ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.