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MODULE VII
MODULE VII

... until after the first trimester, especially when there is danger of drug-induced developmental defects. Potential fetal risks must be compared to maternal benefits when drug therapy is required. Minimum therapeutic dose should be used for as short a time period as possible. ...
ZUCLOPENTHIXOL tab, drops , amp: Class: Typical antipsychotic
ZUCLOPENTHIXOL tab, drops , amp: Class: Typical antipsychotic

... There are no dosage adjustments provided in manufacturer's labeling; however, renal impairment is not likely to influence systemic exposure as the drug undergoes extensive hepatic metabolism and is primarily excreted in the feces. Hepatic Impairment: There are no dosage adjustments provided in manuf ...
Gemzar - Eli Lilly and Company
Gemzar - Eli Lilly and Company

... Gemzar can cause fetal harm when administered to a pregnant woman, based on its mechanism of action. Gemcitabine was teratogenic, embryotoxic, and fetotoxic in mice and rabbits. If this drug is used during pregnancy, or if a ...
Thrombolysis Reversal - Developinganaesthesia
Thrombolysis Reversal - Developinganaesthesia

... administration and giving the protamine. Due to the short half-life of heparin, reductions in the protamine dose must be allowed if more than 30 minutes have elapsed since the IV heparin was administered or the infusion ceased. Remember that protamine in excessive dosage will act as an anticoagulant ...
(HMG-CoA) Reductase Inhibitors
(HMG-CoA) Reductase Inhibitors

... at least one year post-menarche, (for pravastatin, children and adolescents 8-18 years of age regardless of menarchal status) with elevated LDL-C due to heterozygous familial hypercholesterolemia. Safety and efficacy of pitavastatin in pediatric patients have not been established. Safety and effecti ...
Monitoring of adverse drug reactions associated with
Monitoring of adverse drug reactions associated with

... symptoms reported by the patients who experienced adverse drug reactions. The most common systems associated with ADRs in our study were the central nervous system (CNS) followed by musculo-skeletal complaints. This finding is consistent with previous studies which have reported CNS manifestation [1 ...
Melatonin Information for Primary Care – Nov 2014
Melatonin Information for Primary Care – Nov 2014

... May reduce melatonin concentrations. Melatonin may enhance the sedative properties of other drugs acting on the CNS e.g. benzodiazepines. ...
Vistide - Gilead Sciences, Inc.
Vistide - Gilead Sciences, Inc.

... creatinine and urine protein) must be monitored within 48 hours prior to each dose of VISTIDE. Dose adjustment or discontinuation is required for changes in renal function (serum creatinine and/or urine protein) while on therapy. Proteinuria, as measured by urinalysis in a clinical laboratory, may b ...
Sirirat Ularntinon, Dan Tzuang, Gary Dahl and Richard J. Shaw Risperidone
Sirirat Ularntinon, Dan Tzuang, Gary Dahl and Richard J. Shaw Risperidone

... PEDIATRICS is the official journal of the American Academy of Pediatrics. A monthly publication, it has been published continuously since 1948. PEDIATRICS is owned, published, and trademarked by the American Academy of Pediatrics, 141 Northwest Point Boulevard, Elk Grove Village, Illinois, 60007. Co ...
FOSINOPRIL/HCT ACTAVIS 20/12.5 Tablets Name of the medicine
FOSINOPRIL/HCT ACTAVIS 20/12.5 Tablets Name of the medicine

... Head and neck angioedema: Severe life-threatening angioedema has been reported rarely with angiotensin converting enzyme (ACE) inhibitors. The overall incidence is approximately 0.1% to 0.2%. There seems to be no sex difference in the incidence of angioedema or in the predisposition to angioedema in ...
My STIVARGA® (regorafenib):
My STIVARGA® (regorafenib):

... • a rare stomach, bowel, or esophagus cancer called GIST (gastrointestinal stromal tumor) that cannot be treated with surgery or that has spread to other parts of the body and for which they have received previous treatment with certain medicines. ...
The Conjunctiva
The Conjunctiva

... common and usually self-limiting condition. The most common causative organisms are Staphylococcus epidermidis and Staphylococcus aureus but other Gram-positive cocci, including Streptococcus pneumoniae, are also frequent pathogens as are the Gramnegative Haemophilus influenzae and ...
Pobierz plik
Pobierz plik

... and feces were collected on the day before drug dosing for the background count. Then, each rat received a single oral dose of YH-8 at 100 mg/kg, and the excreted urine and excreted feces samples were collected from each rat at 0-5, 5-12, 12-24, 2436, 36-48, 48-60 and 60-72 h after drug administrati ...
Optimal Use of Bendamustine in Chronic Lymphocytic Leukemia
Optimal Use of Bendamustine in Chronic Lymphocytic Leukemia

... 24 months (range, 5-44+ months). The probability of survival after 4 years was 55%. Hematologic toxicity included grade 3 or 4 leukopenia (16% of cycles), thrombocytopenia (3% of cycles), and anemia (1% of cycles). No organ toxicity was reported. Robinson et al24 used a similar regimen for 4-6 cycle ...
nclex study information
nclex study information

... craving for sweets and weight gain. Symptoms begin in the fall, peak in the winter and usually resolve in the spring. Some individuals experience great bursts of energy and creativity in the spring or early summer. Susceptible individuals who work in buildings without windows may experience SAD-type ...
Using this template
Using this template

... Fast acting NSAIDs are the drugs of choice for Acute Gout Anti inflammatory drug Rx. must be continued for 1-2 wks. Colchicine an effective alternative for NSAIDs. Slow to work IAS are highly effective in acute mono arthritis of Gout Oral or parenteral corticosteroids in NSAID intolerance Allopurino ...
Initiating Methadone Treatment: Induction and stabilisation
Initiating Methadone Treatment: Induction and stabilisation

... “Abnormal Normality” ...
Resistance is futile: the bacteriocin model for addressing the
Resistance is futile: the bacteriocin model for addressing the

... taking place in multiple species simultaneously, as is the case with broad-spectrum antibiotics. Secondly, bacteriocins occur in constantly changing and evolving combinations, thus allowing the producer strains to keep pace with emergent resistance in the targets. It is precisely this strategy, i.e. ...
BUSULFEX (BUSULFAN) INJECTION IS A POTENT CYTOTOXIC
BUSULFEX (BUSULFAN) INJECTION IS A POTENT CYTOTOXIC

... Busulfan may be a human carcinogen. Several cases of leukemia have occurred 5-8 years following oral busulfan treatment. Ovarian suppression and amenorrhea commonly occur in premenopausal women undergoing chronic, low-dose busulfan therapy for chronic myelogenous leukemia. Sterility, azoospermia, an ...
Full Prescribing Information
Full Prescribing Information

... • patients with gastric ulcers. Delay in gastric emptying could complicate management. • pregnant women. It is not known whether Hyophen causes fetal harm or can affect reproductive capacity. Only use if clearly needed. • nursing mothers. Only use if clearly needed as methenamine and hyoscya ...
Misoprostol
Misoprostol

... • high variability of plasma levels between and within studies • mean plasma levels after single oral doses show a linear relationship with dose over the range of 200-400 mcg • no accumulation of misoprostol noted in multiple dose studies • serum protein binding less than 90%, concentration-independ ...
Post Operative Nausea & Vomiting
Post Operative Nausea & Vomiting

... Kovac A. A randomized, double-blind controlled trial of three different doses of palonosetron versus placebo in preventing postoperative nausea and vomiting over a 72-hour period. ...
Carbamazepine (Tegretol)
Carbamazepine (Tegretol)

... Question#2: After 2 months ,N.S.’s carbamazepine dose had been increased to 300mg BID.On this regimen she had some reduction in seizure frequency;however,seizure control was still considered unsatisfactory.The steady-state carbamazepine level at this time was reported to be 4mg/L. what are possible ...
Pediatric Sedation - McMaster Faculty of Health Sciences
Pediatric Sedation - McMaster Faculty of Health Sciences

... Medications Recovery and Discharge ...
View Product Information
View Product Information

... patients with renal impairment (creatinine clearance 12 to 119 mL/min/1.73 m ) showed alterations in both quinapril and quinaprilat pharmacokinetics. The Cmax and AUC for quinapril were greater in patients with renal impairment and the elimination half-life tended to be longer. However, these change ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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