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Pirlimycin - American Academy of Veterinary Pharmacology and
Pirlimycin - American Academy of Veterinary Pharmacology and

... Mastitis (treatment)—Cows, lactating: Pirlimycin is indicated in the treatment of clinical and subclinical mastitis caused by Staphylococcus aureus, Streptococcus agalactiae, Streptococcus dysgalactiae, and Streptococcus uberis. {R-1} In refractory cases of chronic Staphylococcus aureus mastitis, ad ...
PRODUCT MONOGRAPH RESTORIL (temazepam) 15 mg and 30
PRODUCT MONOGRAPH RESTORIL (temazepam) 15 mg and 30

... Manifestations of acute overdosage of Restoril (temazepam), as with other benzodiazepines, can be expected to reflect the increasing CNS effects of the drug and include somnolence, confusion and coma, with reduced or absent reflexes. With large overdoses, respiratory depression, hypotension and fina ...
PDF of full prescribing information
PDF of full prescribing information

... Following oral (30 mg) administration of 14C-labelled terconazole, the half-life of elimination from the blood for the parent terconazole was 6.9 hours (range 4.0 - 11.3). Terconazole is extensively metabolized; both the Cmax and AUC for unchanged terconazole represented a very small fraction (2.1% ...
- Wiley Online Library
- Wiley Online Library

... Table 2. ACE inhibitor dosages used in trials ...
Abbreviations for Dosage Forms Found in Inscription, Subscription
Abbreviations for Dosage Forms Found in Inscription, Subscription

... in powder or liquid form. When the capsule is swallowed, the gelatin dissolves in the acid environment of the stomach releasing the material inside. A divided powder, powder in a paper. The drug or drug mixture is wrapped in folded paper. The patient unfolds the paper and transfers the contents to a ...
View Acrobat PDF
View Acrobat PDF

... human dose of 60 mcg/week based on mcg/m2 body surface area). Use in Pregnancy Pregnancy Category B Reproduction studies in rats and rabbits, at doses up to 20 mcg/kg/day and 0.1 mcg/kg/day (approximately 25 times and less than the maximum recommended human dose of 60 mcg/week based on mcg/m2 body s ...
Disease Modifying Drugs in Inflammatory Bowel Disease (IBD)
Disease Modifying Drugs in Inflammatory Bowel Disease (IBD)

... There are very few case reports of an association between cervical cancer and IBD patients taking azathioprine, although there is more evidence available for patients with rheumatoid arthritis or systemic lupus erythematosus. There are occasional reports of IBD patients on immunosuppressive therapy ...
PEPCID® (Famotidine) Tablets
PEPCID® (Famotidine) Tablets

... up to 2000 and 500 mg/kg/day, respectively, and in both species at I.V. doses of up to 200 mg/kg/day, and have revealed no significant evidence of impaired fertility or harm to the fetus due to PEPCID. While no direct fetotoxic effects have been observed, sporadic abortions occurring only in mothers ...
Introduction of two new anaesthetic agents
Introduction of two new anaesthetic agents

... Ropivacine-Why Safer Than Bupivacaine? • Cumulative doses up to 770 mg over 24 hours (intraoperative block plus postoperative infusion) • Continuous epidural infusion at rates up to 28 mg per hour for 72 hours have been well tolerated in adults, ie, 2016 mg plus surgical dose of approximately 100-1 ...
Can and should beta-lactams be given by continuous infusion
Can and should beta-lactams be given by continuous infusion

... Can and Should ß-lactams be Given by Continuous Infusion? John Turnidge Women’s & Children’s Hospital Adelaide ...
Information Guide ot Antidepressants | March 2009
Information Guide ot Antidepressants | March 2009

... switching to escitalopram at 25% of the citalopram dose. Venlafaxine is detectable in the serum and associated with less weight gain in breast-fed infants. Less information is available about burpropion, mirtazepine and trazodone, although the concentrations in breast milk infant serum are low. The ...
COSENTYX® - Medicines.org.au
COSENTYX® - Medicines.org.au

... haemoglobin <8.5 g/dL; pregnant or nursing women; and women of child-bearing potential not using effective contraception during the study. Of the 2,403 patients who were included in the placebo-controlled studies, 79 % were biologic-naïve, 45 % were non-biologic failures, 8 % were biologic failures, ...
PHL 424 5th S
PHL 424 5th S

...  Clindamycin is indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci and staphylococci The high incidence of diarrhea and the occurrence of pseudomembranous colitis limit its use to infections in which it is clearly superior to other agents ...


... [1]. The proof of this statement is that recently at least two important institutions (British Thoracic Society (BTS) and American Thoracic Society (ATS)) have elaborated documents to direct the initial management of community-acquired pneumonia [2, 3]. Whilst the BTS still recommends the use of pen ...
Octaplas For	Coagulation	Disorders NEW	DRUGS
Octaplas For Coagulation Disorders NEW DRUGS

... lead to ulceration and possibly cancer, researchers from the United Kingdom designed a series of nested-control studies using the two largest population databases. They matched patients 50 years of age and older with primary GI tract cancer with up to five controls. No overall association was found ...
Product Monograph - AstraZeneca Canada
Product Monograph - AstraZeneca Canada

... treatment with DAXAS should be stopped in patients with severe immunological diseases (e.g. HIV infection, multiple sclerosis, lupus erythematosus, progressive multifocal leukoencephalopathy) or patients being treated with immunosuppressive medicinal products (e.g. methotrexate, azathioprine, inflix ...
F-PI PDF version
F-PI PDF version

... patients treated for 24 months with KITOSCELL LP™ Tablets. Furthermore, according to the Child-Pugh classification system, it was also observed that in 81% of patients there was no disease progression and their ALT levels were significantly improved. Studies also showed the direct action on fibrosis ...
Pharmaceuticals utilized in stem cell transplant
Pharmaceuticals utilized in stem cell transplant

... Traditionally, dosed based on AUC in solid tumor and lymphoma regimens to limit toxicities Targeted AUC dosing is less well documented in stem cell transplant regimens Utilized in a variety of solid tumor regimens Toxicities: Ototoxicity, hepatoxicity, renal, ...
Pediatric Psychopharmacology
Pediatric Psychopharmacology

... Remember, most meds are reversibly bound to albumin, and only the free unbound portion is active and available for tissue distribution. different sites for acidic drugs (globulin) and basic drugs (a-1 glycoprotein) b/c a-1 glycoprotein is an acute phase reactant, its increased presence during inf ...
BLEPHAMIDE (sulfacetamide sodium
BLEPHAMIDE (sulfacetamide sodium

... conjunctivitides is accepted to obtain diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation or thermal burns or penetration of foreign bodies. The use of a combination drug with an anti-infective component is indicated ...
Angiotensin Receptor Blockers - Advantages of the
Angiotensin Receptor Blockers - Advantages of the

... impairment and hepatic disease decrease the plasma clearance of olmesartan, no dose adjustment is required in patients with mild-to-moderate renal or hepatic impairment. The oral dosage of olmesartan medoxomil is 20-40 mg once daily. If BP is not controlled by olmesartan medoxomil alone, a diuretic ...
Product Monograph
Product Monograph

... majority of instances, such complications begin immediately or soon (<24 hours) after delivery. It should be noted that, in some cases, the clinical picture is consistent with serotonin syndrome. When treating a pregnant woman with TRINTELLIX during later stages of pregnancy, the physician should ca ...
SmartPak Pharmacy
SmartPak Pharmacy

... 3 months thereafter. At a minimum, this monitoring should include a thorough history and physical examination, ACTH stimulation test and serum biochemical tests. A post-ACTH stimulation test resulting in a cortisol of <1.45ug/dl, with or without electrolyte abnormalities, may precede the development ...
Prinivil - Merck.com
Prinivil - Merck.com

... Monitor serum potassium periodically in patients receiving PRINIVIL. Drugs that inhibit the reninangiotensin system can cause hyperkalemia. Risk factors for the development of hyperkalemia include renal insufficiency, diabetes mellitus, and the concomitant use of potassium-sparing diuretics, potassi ...
PRODUCT MONOGRAPH ELAVIL® Amitriptyline Hydrochloride
PRODUCT MONOGRAPH ELAVIL® Amitriptyline Hydrochloride

... This can be increased gradually to 200 mg a day if necessary. A small number of hospitalized patients may need as much as 300 mg a day. Adolescent and Elderly Patients: In general, lower dosages are recommended for these patients. ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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