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Vasopressors and inotropes
Vasopressors and inotropes

... be given as a single IV dose (40 units) to replace the first or second dose of epinephrine. In cases of septic shock that are resistant, or refractory, to hemodynamic support with norepinephrine or dopamine, a vasopressin infusion can be used to raise the blood pressure and reduce the catecholamine ...
Drugs and Coagulation at Point of Care
Drugs and Coagulation at Point of Care

... • Advantages – Better bioavailability – Longer half-life – Administered subcutaneously either once or twice daily – More predictable dose response – HIT Type II occurs less often with LMWH ...
Epilim Chrono
Epilim Chrono

... (see aspirin/salicylate product information on Reye’s syndrome). Monotherapy is recommended in children under the age of 3 years when prescribing Epilim, but the potential benefit of Epilim should be weighed against the risk of liver damage or pancreatitis in such patients prior to initiation of the ...


... Western Canada justifying: continued use of oral amoxicillin (best activity of any oral β-lactam agent) for mild-moderate infections & Ceftriaxone for more serious infections Pen IV can be used if penicillin S confirmed Significant resistance to macrolides (21-29%), clindamycin (14%), and ...
A	Literature	Review	Examining	the	Use	of	Combina9on	Inhaler	Tiotropium/Olodaterol	in	COPD
A Literature Review Examining the Use of Combina9on Inhaler Tiotropium/Olodaterol in COPD

... •  In the VIVACITO invesPgaPonal study adverse events were of similar incident rates across the treatment arms with the most common events being nasopharyngiPs and COPD worsening.5 •  ANHELTO 1 and 2 are replicate, double blind, randomized, 12-week studies that saw significant improvements in the ...
NUROFEN PLUS
NUROFEN PLUS

... especially in patients with documented hepatic or renal function impairment. The same monitoring may also be required in patients known or suspected to be at risk for renal function impairment, patients taking diuretics concurrently, and in patients in whom signs of possible renal toxicity occur, su ...


... recorded at intervals during their treatment. FEV1, FVC, and quality of life measurements were also recorded. The US study was a multicentre, double-blind, controlled trial in which 181 clinically stable CF patients, whose FVC was more than 40% predicted at baseline and who were 8 yrs of age or olde ...
Users` Guides to the Medical Literature
Users` Guides to the Medical Literature

... with respect to determinants of outcome that we know about, but also those we do not know about. In prior articles in this series, we have shown how readers of articles about therapy can use the results of RCTs.2·3 Randomized controlled trials are rarely done to study possible harmful expo¬ sures, b ...
ECX Regimen - Cancer Care Ontario
ECX Regimen - Cancer Care Ontario

... syndrome in patients receiving capecitabine. • Supportive care should be provided, including loperamide for diarrhea. Also refer to CCO Antiemetic Summary back to top ...
the DETROL LA Diary
the DETROL LA Diary

... Potent CYP3A4 Inhibitors: Coadministration may increase systemic exposure to DETROL LA. Reduce DETROL LA dose to 2 mg once daily. (7.2) ...
PPT
PPT

... • In fit elderly patients < 80 years old SBP values <140 mmHg may be considered, whereas in the fragile elderly population SBP goals should be adapted to individual tolerability (IIb C) • If > 80 years and with initial SBP ≥160 mmHg, it is recommended to reduce SBP to between 150 and 140 mmHg provid ...
20810 AlleRx DF.indd
20810 AlleRx DF.indd

... 30 white elongated and scored AM tablets debossed with “CBP” on one side and “03” to the right of the score on the other side, each containing 4 mg of chlorpheniramine maleate and 2.5 mg of methscopolamine nitrate. 30 blue, elongated and scored PM tablets debossed with “CBP” on one side and “02” to ...
PRODUCT MONOGRAPH
PRODUCT MONOGRAPH

... observed in the clinical trials may not reflect the rates observed in practice and should not be compared to the rates in the clinical trials of another drug. Adverse drug reaction information from clinical trials is useful for identifying drug-related adverse events and for approximating rates. The ...
Parnate - GSK.ca
Parnate - GSK.ca

... and should adjust dosage carefully. A marked potentiating effect has been reported on some central nervous system depressants such as morphine, meperidine, barbiturates and alcohol. For this reason, narcotics and barbiturates should be used conservatively with PARNATE®, and patients should be warned ...
Product Information: Mycophenolate sodium
Product Information: Mycophenolate sodium

... groups. Most patients had a histological diagnosis of Class IV lupus nephritis. At 6 months, 8/42 (19.0%) of Myfortic and standard corticosteroid-treated patients and 8/39 (20.5%) of Myfortic and reduced corticosteroid-treated patients achieved complete remission. Partial response occurred in 20/42 ...


... in rats and rabbits at doses up to 50 and 6 times the maximum recommended human dose have revealed no evidence of teratogenic effects or of selective toxicity to the fetus. However, there are no adequate and well-controlled studies in pregnant women. Paxil should be used in pregnancy only if the ben ...
1 of 14 Chlorpromazine Hydrochloride Tablets, USP Rx only
1 of 14 Chlorpromazine Hydrochloride Tablets, USP Rx only

... following abrupt withdrawal of high-dose therapy, some symptoms resembling those of physical dependence such as gastritis, nausea and vomiting, dizziness and tremulousness. These symptoms can usually be avoided or reduced by gradual reduction of the dosage or by continuing concomitant anti-parkinson ...
Glaucomas
Glaucomas

... • rarely used (eg angle-closure glaucoma and some secondary glaucomas), seek specialist advice • increases aqueous outflow • high incidence of adverse effects, eg blurred vision, headache ...
Clinical trial with Secnidazole in a single dose in venezuelan
Clinical trial with Secnidazole in a single dose in venezuelan

... Abstract. The aim of this work was to evaluate in an open, noncomparative study the use of secnidazole in oral suspension given to Venezuelan children infected with Giardia intestinalis, from a community in Carapita, a slum area in Caracas. Seventy children from 2 to 11 years old (38 males and 32 fe ...
marquis - Merial Equine Rebates
marquis - Merial Equine Rebates

... Changes in clinical condition were evaluated first by the subjective scoring of the investigator, then by masked assessment of videotapes of the neurological examination. At 5 mg/kg for 28 days, 28 of 47 horses (60%) improved at least one grade by Day 118. Seventy-five percent (75%) of those improve ...
Single-Dose Oritavancin Versus 7–10 Days of
Single-Dose Oritavancin Versus 7–10 Days of

... 95% CI, −3.7 to 5.0) for oritavancin vs vancomycin, respectively. Efficacy outcomes by pathogen, including methicillin-resistant Staphylococcus aureus and the frequency of adverse events, were similar between treatment groups. Conclusions. A single 1200-mg dose of oritavancin was noninferior to 7–10 ...
Excess mortality in patients with asthma on long-acting b -agonists 2
Excess mortality in patients with asthma on long-acting b -agonists 2

... significantly (p,0.05) more frequently in the salmeterol group: 1) respiratory-related deaths (24 out of 13,176 versus 11 out of 13,179 cases, RR 2.2); 2) combined asthma-related death or lifethreatening experiences (37 versus 22 cases, RR 1.71); and 3) asthma-related deaths (13 versus three cases, ...
dexamethasone sodium phosphate - Fresenius Kabi
dexamethasone sodium phosphate - Fresenius Kabi

... Psychic derangements may appear when corticosteroids are used, ranging from euphoria, insomnia, mood swings, personality changes, and severe depression to frank psychotic manifestations. Also, existing emotional instability or psychotic tendencies may be aggravated by corticosteroids. Aspirin should ...
53rd ASH® Annual Meeting and Exposition
53rd ASH® Annual Meeting and Exposition

... and How to Use Them What are PDA downloads? Blood PDA downloads are summaries of the latest Blood content sent directly to your Palm PDA or PocketPC PDA. The summaries consist of tables of contents, article abstracts, and full-text Inside Blood commentaries. Why use PDA downloads? Use Blood PDA down ...
PDF
PDF

... synthesis, may make it difficult to get pregnant. You should inform your doctor if you plan a pregnancy or if you have problems getting pregnant. Driving and using machines Since the use of Fasdol at higher doses can cause CNS side effects such as fatigue and dizziness and may in some cases change t ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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