Prolixin/Prolixin Decanoate (fluphenazine)
... Prolixin is a relatively high-potency agent, compared with other first-generation antipsychotics such as Thorazine (chlorpromazine) and Mellaril (thioridazine). The high-potency antipsychotics are less sedating and have fewer anticholinergic side effects, but they frequently cause EPS. Prolixin was ...
... Prolixin is a relatively high-potency agent, compared with other first-generation antipsychotics such as Thorazine (chlorpromazine) and Mellaril (thioridazine). The high-potency antipsychotics are less sedating and have fewer anticholinergic side effects, but they frequently cause EPS. Prolixin was ...
Use Of Oral Anti-Diabetic Agents In Diabetes With Chronic Kidney
... tubules and is also degraded by the tubular cells into amino acids which are reabsorbed. The final result of all these processes is that only 1% of the filtered insulin appears in the urine. In patients with renal disease, basal insulin levels are high. The reasons for this vary according to the sta ...
... tubules and is also degraded by the tubular cells into amino acids which are reabsorbed. The final result of all these processes is that only 1% of the filtered insulin appears in the urine. In patients with renal disease, basal insulin levels are high. The reasons for this vary according to the sta ...
viva question
... 2. Once daily extended interval dosing is more preferred based on the principal of conc. dependent killing, post antibiotic effects, reduction in renal accumulation and less chances of induction of resistance in bacteria 3. Initial dosage for this regimen is 3-7mg/kg/day 4. This is subsequently adju ...
... 2. Once daily extended interval dosing is more preferred based on the principal of conc. dependent killing, post antibiotic effects, reduction in renal accumulation and less chances of induction of resistance in bacteria 3. Initial dosage for this regimen is 3-7mg/kg/day 4. This is subsequently adju ...
diuretics
... MCQ – Matching type One of the following diuretic is NOT properly matched with its indication for use A. Hydrochlorothiazide – Diabetes insipidus B. Eplerenone – Hypertension C. Mannitol – Acute pulmonary edema D. Spironolactone – Edema in cirrhosis of liver ...
... MCQ – Matching type One of the following diuretic is NOT properly matched with its indication for use A. Hydrochlorothiazide – Diabetes insipidus B. Eplerenone – Hypertension C. Mannitol – Acute pulmonary edema D. Spironolactone – Edema in cirrhosis of liver ...
Effects of celiprolol, a cardioselective ... respiratory function in asthmatic patients
... The risk of developing bronchospasm following administration of beta-blockers is particularly high in asthmatic patients. This phenomenon can probably be explained by simultaneous blockade of 13 1 and !32 receptors [11]. The persistence of a bronchodilatory effect with salbutamol confirms that with ...
... The risk of developing bronchospasm following administration of beta-blockers is particularly high in asthmatic patients. This phenomenon can probably be explained by simultaneous blockade of 13 1 and !32 receptors [11]. The persistence of a bronchodilatory effect with salbutamol confirms that with ...
Antibiotics *part 2
... 1. It is still recommended as an important and useful drug for the treatment of many Gram-positive organisms, such as streptococci, pneumococci, gonococci, and meningococci infections. 2. It is mostly destroyed by gastric juice and is, therefore, not given by oral route, and is best administered as ...
... 1. It is still recommended as an important and useful drug for the treatment of many Gram-positive organisms, such as streptococci, pneumococci, gonococci, and meningococci infections. 2. It is mostly destroyed by gastric juice and is, therefore, not given by oral route, and is best administered as ...
Stage C – More on β
... high-dose, High-dose Losartan main effect was in reduction in hospitalization for HR ★ Heart failure experts typically will not use Losartan as an ARB alternative, but will go with candesartan or valsartan based on evidence currently available. Stage C – ARB plus ACEI - 47 • Class IIB - The addition ...
... high-dose, High-dose Losartan main effect was in reduction in hospitalization for HR ★ Heart failure experts typically will not use Losartan as an ARB alternative, but will go with candesartan or valsartan based on evidence currently available. Stage C – ARB plus ACEI - 47 • Class IIB - The addition ...
The Difficult to Sedate ICU Patient
... Phencyclidine derivative (like PCP) NMDA receptor antagonist Dissociative hypnotic, amnestic Analgesic – The only potent analgesic without much respiratory depression – One of the few non-opioid analgesics that can be given IV ...
... Phencyclidine derivative (like PCP) NMDA receptor antagonist Dissociative hypnotic, amnestic Analgesic – The only potent analgesic without much respiratory depression – One of the few non-opioid analgesics that can be given IV ...
06_Multiple dosing Extravascular Administration
... QJ is a 67-year-old, 80-kg male being treated for chronic obstructive pulmonary disease. Sustained-release oral theophylline is being added to his drug regimen. Assuming F = 1.0, V = 40 L, and t1/2 = 5 hours, compute an oral theophylline dose to be administered every 12 hours that would achieve a Cs ...
... QJ is a 67-year-old, 80-kg male being treated for chronic obstructive pulmonary disease. Sustained-release oral theophylline is being added to his drug regimen. Assuming F = 1.0, V = 40 L, and t1/2 = 5 hours, compute an oral theophylline dose to be administered every 12 hours that would achieve a Cs ...
PRODUCT MONOGRAPH
... Special Populations Pregnant Women The safety of desvenlafaxine in human pregnancy has not been established. The extent of exposure to PRISTIQ in pregnancy during clinical trials was very limited. There are no adequate and well-controlled studies in pregnant women. Therefore, desvenlafaxine should b ...
... Special Populations Pregnant Women The safety of desvenlafaxine in human pregnancy has not been established. The extent of exposure to PRISTIQ in pregnancy during clinical trials was very limited. There are no adequate and well-controlled studies in pregnant women. Therefore, desvenlafaxine should b ...
Inhaled loxapine: A novel treatment for agitation in psychotic disorders
... in order to manage the high risk of violence by a patient. This, in turn, is a prerequisite of providing safety for a patient him- or herself, as well as all the other individuals involved in the emergency situation (i.e. staff members, other patients, and hospital guests) [3-6]. It is also worth me ...
... in order to manage the high risk of violence by a patient. This, in turn, is a prerequisite of providing safety for a patient him- or herself, as well as all the other individuals involved in the emergency situation (i.e. staff members, other patients, and hospital guests) [3-6]. It is also worth me ...
khedezla - Pernix Therapeutics
... phases of treatment. Pooled analyses of short-term placebo-controlled studies of antidepressant drugs (SSRIs and others) showed that these drugs increase the risk of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults (ages 18 to 24) with major depressive disorder ...
... phases of treatment. Pooled analyses of short-term placebo-controlled studies of antidepressant drugs (SSRIs and others) showed that these drugs increase the risk of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults (ages 18 to 24) with major depressive disorder ...
STOPP START Toolkit Supporting Medication Review
... Many anticholinergic (antimuscarinic) drugs are included in the STOPP sections already but as combining anticholinergic drugs increases the risk of side effects (including confusion, falls and death) the Anticholinergic Cognitive Burden scale9 for some commonly prescribed drugs is given on page 26 a ...
... Many anticholinergic (antimuscarinic) drugs are included in the STOPP sections already but as combining anticholinergic drugs increases the risk of side effects (including confusion, falls and death) the Anticholinergic Cognitive Burden scale9 for some commonly prescribed drugs is given on page 26 a ...
ASEC 2014 Understanding the Unwanted Side Effects of the
... adsorbed to the plastic and only the propylene glycol carrier base is administered to the patient. Because of the propylene glycol base, diazepam is not compatible when physically mixed with any other drugs or solutions. Traditional dosing of diazepam in dogs and cats is between 0.1 to 0.6 mg/kg IV ...
... adsorbed to the plastic and only the propylene glycol carrier base is administered to the patient. Because of the propylene glycol base, diazepam is not compatible when physically mixed with any other drugs or solutions. Traditional dosing of diazepam in dogs and cats is between 0.1 to 0.6 mg/kg IV ...
nabilone - Valeant
... 1) Due to similar qualitative and quantitative cannabis-like effects with delta-9-tetrahydrocannabinol (THC) (marijuana), nabilone has potential for abuse. No patients experienced withdrawal symptoms after stopping nabilone during clinical trials of up to 5 days' duration. The frequency of psycholog ...
... 1) Due to similar qualitative and quantitative cannabis-like effects with delta-9-tetrahydrocannabinol (THC) (marijuana), nabilone has potential for abuse. No patients experienced withdrawal symptoms after stopping nabilone during clinical trials of up to 5 days' duration. The frequency of psycholog ...
Announcing the 50 mg capsule
... Patients receiving GENGRAF require frequent monitoring of serum creatinine. Elderly significant drug interactions. patients should be monitored with particular care, since decreases in renal function Pregnancy: GENGRAF is Pregnancy Category C and should not be used during pregnancy occur with age. u ...
... Patients receiving GENGRAF require frequent monitoring of serum creatinine. Elderly significant drug interactions. patients should be monitored with particular care, since decreases in renal function Pregnancy: GENGRAF is Pregnancy Category C and should not be used during pregnancy occur with age. u ...
Review of Psychotropic Drugs 2009
... tachycardia; hypertension (elevated blood pressure); and increased respiratory rate. (Springhouse Nurse’s Drug Guide, 2004) Encourage good dental hygiene since persistent dry mouth may increase the risk of dental caries. 5. Extrapyramidal Side Effects--This is a collection of abnormal movements affe ...
... tachycardia; hypertension (elevated blood pressure); and increased respiratory rate. (Springhouse Nurse’s Drug Guide, 2004) Encourage good dental hygiene since persistent dry mouth may increase the risk of dental caries. 5. Extrapyramidal Side Effects--This is a collection of abnormal movements affe ...
The strategies of treatment of atrial fibrillation in the elderly
... patients. Sinus rhythm can be achieved with class Ic or class III antiarrhythmic drugs and/or electrical cardioversion. If structural heart disease is found class Ic agents should be avoided (21, 22). Current evidence indicates that in people without significant symptoms of AF, clinical outcomes of ...
... patients. Sinus rhythm can be achieved with class Ic or class III antiarrhythmic drugs and/or electrical cardioversion. If structural heart disease is found class Ic agents should be avoided (21, 22). Current evidence indicates that in people without significant symptoms of AF, clinical outcomes of ...
Introduction
... the ion exchange at the endplate of the synapse which leads to further weakness of neuromuscular transmission and reduces the ability of cholinesterase inhibitors to reverse the action. Pancuronium is a long acting aminosterodial nondepolarzing NMBA with a peak effect occurring within 2-3 minutes an ...
... the ion exchange at the endplate of the synapse which leads to further weakness of neuromuscular transmission and reduces the ability of cholinesterase inhibitors to reverse the action. Pancuronium is a long acting aminosterodial nondepolarzing NMBA with a peak effect occurring within 2-3 minutes an ...
Get the Facts about Zohydro™ ER
... Extended-Release Capsules, CII, fills an unmet need for a subset of severe chronic pain patients who cannot take acetaminophen. ...
... Extended-Release Capsules, CII, fills an unmet need for a subset of severe chronic pain patients who cannot take acetaminophen. ...
Drugs and the kidney
... This article on drug nephrotoxicity is detailed, as it is important to be fully aware of renal side-effects of drugs with regard to prevention and early diagnosis in order to manage the condition correctly. Many therapeutic agents are nephrotoxic, particularly when the serum half-life is prolonged a ...
... This article on drug nephrotoxicity is detailed, as it is important to be fully aware of renal side-effects of drugs with regard to prevention and early diagnosis in order to manage the condition correctly. Many therapeutic agents are nephrotoxic, particularly when the serum half-life is prolonged a ...
renal impairment studies in early development services
... and negatively impact timelines, as well as the successful conduct of the study. By following the appropriate criteria, PRA’s PPS group usually targets an accelerated recruitment rate of four to six patients per investigational site, per month. Patients enrolled into these special population trials ...
... and negatively impact timelines, as well as the successful conduct of the study. By following the appropriate criteria, PRA’s PPS group usually targets an accelerated recruitment rate of four to six patients per investigational site, per month. Patients enrolled into these special population trials ...
Size: 841 kB 25th Aug 2014 Pharmacology Basics
... • Factors such as genetic disposition, environment, nutrition and age can influence drug metabolism ...
... • Factors such as genetic disposition, environment, nutrition and age can influence drug metabolism ...
Datasheet Methylprednisolone Sodium Succinate
... recommended rate of administration. However, if used for longer than 48 to 72 hours continuously, severe endocrinological and cardiovascular side effects can occur. Secondary adrenocortical insufficiency leading to adrenal atrophy and generalised protein depletion have been reported. High dose intra ...
... recommended rate of administration. However, if used for longer than 48 to 72 hours continuously, severe endocrinological and cardiovascular side effects can occur. Secondary adrenocortical insufficiency leading to adrenal atrophy and generalised protein depletion have been reported. High dose intra ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.