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Pandemic Influenza Viruses — Hoping for the Road Not Taken
Pandemic Influenza Viruses — Hoping for the Road Not Taken

... that they either had a direct avian origin or an evolutionarily brief preliminary period in another host. The relative protection in 1918 of people older than 65, however, suggests that a related virus was circulating after the 1830 pandemic.5 That possibility is important because if the 1918 virus ...
Zoonoses and You
Zoonoses and You

...  The fungal spores become airborne when the soil is disturbed  People breathe in the spores and become infected ...
you cannot “kill” a virus
you cannot “kill” a virus

... Tend to be species-specific Reside in a reservoir host in which they cause limited pathology or are chronic Disease usually occurs when the virus “jumps” species Deer mice permanently host Sin Nombre hantavirus without pathology (disease) Humans infected with SNV often develop hantavirus cardiopulmo ...
Swine Flu - RBS Medical
Swine Flu - RBS Medical

... • Swine influenza is a respiratory disease of pigs caused by type A influenza virus that regularly causes influenza outbreaks. ...
Instructions for the classification of influenza viruses
Instructions for the classification of influenza viruses

... Under exceptional circumstances and when limited virological and epidemiological information is available, Low Pathogenic Avian Influenza (LPAI) viruses causing severe disease in humans should be classified as Category A when transported in live form with potential to cause harm to otherwise healthy ...
Control and prevention of infectious bursal disease: a review
Control and prevention of infectious bursal disease: a review

... by the combined use of live virus and inactivated oil emulsion vaccines. But these vaccines are not always safe as they may not contain the required immunogens present in the variant strains prevailing in that area. Thus new technologies and second-generation vaccines including rationally designed r ...
Introduction to Viruses 1
Introduction to Viruses 1

...  5000 influenza viruses can fit on the head of a pin ...
Statement on Use of Antibiotic Feed Additives by the Poultry Industry
Statement on Use of Antibiotic Feed Additives by the Poultry Industry

... Statement on Use of Antibiotic Feed Additives by the Poultry Industry Submitted by AAAP Drugs & Therapeutics Committee (Jan 2016) Approved by AAAP Board of Directors (Feb 2016) The American Association of Avian Pathologists (AAAP) is a professional organization of poultry veterinarians and scientist ...
COMPUTATIONAL ANTIVIRAL DRUG DESIGN
COMPUTATIONAL ANTIVIRAL DRUG DESIGN

... Influenza is a substantial problem in today’s society. Each year 36,000 people die in the United States due to influenza, or influenza related causes. Influenza is caused by two types of the virus, Type-A and Type-B. There are currently four FDA approved drugs to treat influenza—two are proton chann ...
Specific Aims. The long term goal of this research project is to
Specific Aims. The long term goal of this research project is to

... inhibitors have been used for the prevention and/or treatment of influenza. However, they often fail because treatment with these drugs leads to the emergence of resistant viruses in the treated population. Adamantanes have historically been used in the treatment and prevention of influenza A virus ...
disease emergence and re-emergence
disease emergence and re-emergence

... genome, which has eight genes, facilitates reassortment; up to 256 gene combinations are possible during coinfection with human and non-human viruses. Antigenic shift can arise when genes encoding at least the haemagglutinin surface glycoprotein are introduced into people, by direct transmission of ...
Mycoplasma gallisepticum
Mycoplasma gallisepticum

... common means of introduction, as the disease has been eradicated from most primary and multiplier breeding flocks. M. gallisepticum – negative breeding stock can be identified and maintained by serologic testing. Heat treatment or Tiamulin can eliminate egg transmission from valuable breeding animal ...
Emerging Diseases Escherichia coli
Emerging Diseases Escherichia coli

... appear as the result of antigenic shift, which causes new combinations of proteins on the surface of the virus. If the new virus spreads easily from person to person a pandemic can result. ...
igotmadhopz4anazn The Deadly Spanish Influenza The 1918
igotmadhopz4anazn The Deadly Spanish Influenza The 1918

... structure. Due to its constant mutations(changes in genetic structure) and changes that viruses go through each year, the human immune system cannot always defend the human body against these influenzas. One of the mutations was the hemagluttin protein, a protein that causes blood to clot, which was ...
- AAP Red Book - American Academy of Pediatrics
- AAP Red Book - American Academy of Pediatrics

... ...
Capua - Institute on Science for Global Policy
Capua - Institute on Science for Global Policy

... H5N1, the future occurrence of a severe influenza pandemic cannot be ruled out. Avian viruses (e.g., H5N1) and others with zoonotic potential (e.g., H9N2) are still endemic in large portions of the eastern hemisphere. Swine influenza viruses and other mammalian viruses are also circulating at a glob ...
        
        

... 3ft, and 6ft of the patient’s head during routine care. Influenza was detected by rapid test, and PCR.   Results: Sixty‐one (65%) of 94 subjects tested influenza positive.  Twenty‐six (43%) released influenza  into room air, with five patients (19%) emitting up to 32times more virus than others. Emi ...
GE Healthcare and Novavax to Develop and Market Pandemic
GE Healthcare and Novavax to Develop and Market Pandemic

... disease, so that patients can live their lives to the fullest. ...
Lecture 12 - Viral Diseases 2 slides per page
Lecture 12 - Viral Diseases 2 slides per page

... attenuated vaccine recently introduced treatment (influenza specific medications) amantadine, rimantadine ‐ interfere with uncoating process neuraminidase inhibitors (Tamiflu, Relenza) ...
Influenza Final 1-04
Influenza Final 1-04

... that will likely prevail in the coming flu season. Vaccination is recommended in the fall for elders, children, persons with chronic illnesses and impaired immunity, and health care workers. The vaccine is usually very effective. However, the virus can often change (or mutate) to another strain late ...
DIAGNOSIS OF SWINE FLU
DIAGNOSIS OF SWINE FLU

... influenza virus as influenza A (H1N1) or "Influenza A (H1N1) virus, human" ...
Bats, Rats, Monkeys... Oh My! - Global Health Mini
Bats, Rats, Monkeys... Oh My! - Global Health Mini

... • Often use “vertical” programs focused on specific infectious diseases that commonly affect humans • Weak linkages with wildlife and domestic animal health • Emerging infectious diseases in animal populations often not detected until there is an unusual cluster of human cases • Limited ability to a ...
Pandemic Influenza
Pandemic Influenza

... Avian influenza, or “bird flu,” is a contagious disease of animals caused by viruses that normally infect only birds, and less commonly, pigs. Most strains pose no threat to human health. However, one particular strain (H5N1) is extremely infectious and fatal to chickens and ducks, and in some insta ...
Diseases from the Past
Diseases from the Past

... and lymphocyte can be found near the site of an infection, and the two act in concert to help eliminate it. ...
The Great Influenza - George Mason University
The Great Influenza - George Mason University

... vaccinated and several hundred may -- or may not -- have developed a nerve disorder as a result. In 1997, to prevent the spread of a Hong Kong flu virus that killed six people, every chicken in the city was destroyed, 1.2 million birds. Last year, after a new strain emerged on European poultry farms ...
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Avian influenza

Avian influenza — known informally as avian flu or bird flu — refers to ""influenza caused by viruses adapted to birds."" The type with the greatest risk is highly pathogenic avian influenza (HPAI).""Bird flu"" is a phrase similar to ""swine flu,"" ""dog flu,"" ""horse flu,"" or ""human flu"" in that it refers to an illness caused by any of many different strains of influenza viruses that have adapted to a specific host. All known viruses that cause influenza in birds belong to the species influenza A virus. All subtypes (but not all strains of all subtypes) of influenza A virus are adapted to birds, which is why for many purposes avian flu virus is the influenza A virus. (Note, however, that the ""A"" does not stand for ""avian"").Adaptation is not exclusive. Being adapted toward a particular species does not preclude adaptations, or partial adaptations, toward infecting different species. In this way, strains of influenza viruses are adapted to multiple species, though may be preferential toward a particular host. For example, viruses responsible for influenza pandemics are adapted to both humans and birds. Recent influenza research into the genes of the Spanish flu virus shows it to have genes adapted to both birds and humans, with more of its genes from birds than less deadly later pandemic strains.While its most highly pathogenic strain (H5N1) had been spreading throughout Asia since 2003, avian influenza reached Europe in 2005, and the Middle East, as well as Africa, the following year. On January 22, 2012, China reported its second human death due to bird flu in a month following other fatalities in Vietnam and Cambodia. Companion birds in captivity and parrots are highly unlikely to contract the virus, and there has been no report of a companion bird with avian influenza since 2003. Pigeons do not contract or spread the virus. 84% of affected bird populations are composed of chicken and farm birds, while the 15% is made up of wild birds according to capture-and-release operations in the 2000s, during the SARs pandemic. The first deadly Canadian case was confirmed on January 3, 2014. On December 2, 2014, two turkey farms in British Columbia, Canada, had been placed under quarantine after the Canadian Food Inspection Agency confirmed an avian flu outbreak.
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