Systems biology in vaccine design
... is a biological preparation that improves immunity to a particular disease upon administration to an animal/ human. A vaccine typically contains one or several antigens that resemble a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its derived antige ...
... is a biological preparation that improves immunity to a particular disease upon administration to an animal/ human. A vaccine typically contains one or several antigens that resemble a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its derived antige ...
IMMUNE RESPONSES AGAINST MYCOBACTERIUM
... Background: Tuberculosis is a worldwide problem particularly in developing countries. Different clinical outcomes, such as the asymptomatic phase during infection or the symptomatic stage during active disease leads to activation and expansion of cellular immune responses in order to control the inf ...
... Background: Tuberculosis is a worldwide problem particularly in developing countries. Different clinical outcomes, such as the asymptomatic phase during infection or the symptomatic stage during active disease leads to activation and expansion of cellular immune responses in order to control the inf ...
Immunity
... tolerance to them. – Clonal Deletion: B and T cells that react against self antigens appear to be destroyed during fetal development. Process is poorly understood. Dr. Mohamed Farouk Elshal ...
... tolerance to them. – Clonal Deletion: B and T cells that react against self antigens appear to be destroyed during fetal development. Process is poorly understood. Dr. Mohamed Farouk Elshal ...
MUKOSA-SISTEM-IMMUN-BAKTERI-VIRUS-CACING
... Entry of nonpathogenic antigens e.g. food proteins Musketeers Course October 2008 ...
... Entry of nonpathogenic antigens e.g. food proteins Musketeers Course October 2008 ...
Viral Vaccines - Molecular Immunology
... have several advantages • Attenuated (weakened) form of the "wild" virus or bacterium • Can replicate themselves so the immune response is more similar to natural infection • Usually effective with one dose ...
... have several advantages • Attenuated (weakened) form of the "wild" virus or bacterium • Can replicate themselves so the immune response is more similar to natural infection • Usually effective with one dose ...
Chapter 1 – Introduction to the Immune Response
... interstitial fluid, tissues and blood, and to destroy infected host cells so that neighboring host cells do not share their fate. Because pathogens are constantly evolving mechanisms to evade or block immune defenses, the immune system must constantly adapt to maintain its effectiveness. It is a con ...
... interstitial fluid, tissues and blood, and to destroy infected host cells so that neighboring host cells do not share their fate. Because pathogens are constantly evolving mechanisms to evade or block immune defenses, the immune system must constantly adapt to maintain its effectiveness. It is a con ...
Correlations among measles virus
... cellular immunity in populations several years after vaccination and understand the correlations among these measures of immunity. We examined measles-specific antibodies, lymphoproliferation and the Th1/Th2 signature cytokines, interferon (IFN)-γγ and interleukin (IL)-4, in a population-based cohor ...
... cellular immunity in populations several years after vaccination and understand the correlations among these measures of immunity. We examined measles-specific antibodies, lymphoproliferation and the Th1/Th2 signature cytokines, interferon (IFN)-γγ and interleukin (IL)-4, in a population-based cohor ...
Theory and Practice of Immunocontraception in Wild Mammals
... Immunocontraceptionhas been proposed as a technique for managingwildlife populations in urbanand suburbansettingswhere traditional,lethal control methods may not be publicly acceptable. Immunocontraceptionuses an animal's own immune response to disruptreproductivefunction. Proteinsof eggs, sperm, fe ...
... Immunocontraceptionhas been proposed as a technique for managingwildlife populations in urbanand suburbansettingswhere traditional,lethal control methods may not be publicly acceptable. Immunocontraceptionuses an animal's own immune response to disruptreproductivefunction. Proteinsof eggs, sperm, fe ...
Genetic influence on disease spread following arrival of infected
... Matthews & Woolhouse 2005; Cook et al. 2007). This theory has been developed to reflect a variety of parasite life-cycles, including vertical transmission or horizontal transmission either by direct contact or autonomous infectious forms (e.g. Anderson & May 1992; Lipsitch et al. 1995; Matthews & Wo ...
... Matthews & Woolhouse 2005; Cook et al. 2007). This theory has been developed to reflect a variety of parasite life-cycles, including vertical transmission or horizontal transmission either by direct contact or autonomous infectious forms (e.g. Anderson & May 1992; Lipsitch et al. 1995; Matthews & Wo ...
Review articles Mucosal vaccination – an old but still vital strategy1
... vaccination represents many advantages (such as high efficacy, low cost, no hazard) as compared to parenteral routes, only a small number of oral vaccines are routinely available today [20]. ...
... vaccination represents many advantages (such as high efficacy, low cost, no hazard) as compared to parenteral routes, only a small number of oral vaccines are routinely available today [20]. ...
Proceedings Template - WORD
... population to revert to the activated state. Second, the bistability allows the GDP mechanism to operate effectively against pathogen populations that exhibit logistic growth up to a carrying capacity. In this case, even though the antigen population ceases to increase once the pathogen has reached ...
... population to revert to the activated state. Second, the bistability allows the GDP mechanism to operate effectively against pathogen populations that exhibit logistic growth up to a carrying capacity. In this case, even though the antigen population ceases to increase once the pathogen has reached ...
Immune-Genetic Algorithm for Traveling Salesman Problem
... “local” search (Potvin, 1996) (Jin et al., 1996) (Wei & Lee, 2004) (Lu et al., 1996). Although TSP itself seems very simple, as the number of visited cities increases, the computation of the problem can be extremely time-consuming (in the order of exponential growth) or even results in no optimal so ...
... “local” search (Potvin, 1996) (Jin et al., 1996) (Wei & Lee, 2004) (Lu et al., 1996). Although TSP itself seems very simple, as the number of visited cities increases, the computation of the problem can be extremely time-consuming (in the order of exponential growth) or even results in no optimal so ...
A review on transfer factor an immune modulator
... HIV-infected patients. Russ J HIV/AIDS Relat Probl. 2002;6:79e80. Pilotti V, Mastrorilli M, Pizza G, et al. Transfer factor as an adjuvant to non-small cell lung cancer therapy. Biotherapy. 1996;9:117e121. Milich DR, Chen MK, Hughes JL, Jones JE. The secreted hepatitis precove antigen can modulate t ...
... HIV-infected patients. Russ J HIV/AIDS Relat Probl. 2002;6:79e80. Pilotti V, Mastrorilli M, Pizza G, et al. Transfer factor as an adjuvant to non-small cell lung cancer therapy. Biotherapy. 1996;9:117e121. Milich DR, Chen MK, Hughes JL, Jones JE. The secreted hepatitis precove antigen can modulate t ...
EpiCor® and its Immune Effects on Gut Health SCIENCE REPORT
... in particular butyrate. Apart from butyrate’s association with energy, it is thought to interact directly with parts of the immune and digestive systems. Research has shown butyrate’s beneficial effects on the structure of the gut wall and on its ability to alter cytokine profiles in such a way tha ...
... in particular butyrate. Apart from butyrate’s association with energy, it is thought to interact directly with parts of the immune and digestive systems. Research has shown butyrate’s beneficial effects on the structure of the gut wall and on its ability to alter cytokine profiles in such a way tha ...
immune system
... During the clonal expansion the average antibody affinity for the antigen that triggered the clonal expansion is increasing. ( affinity maturation) Affinity maturation is a result of the hypermutation mechanism proportional to the affinity binding. The higher the affinity, the less mutation it suffe ...
... During the clonal expansion the average antibody affinity for the antigen that triggered the clonal expansion is increasing. ( affinity maturation) Affinity maturation is a result of the hypermutation mechanism proportional to the affinity binding. The higher the affinity, the less mutation it suffe ...
pdf
... syndrome. Here, as part of our broader investigation into behavioural syndromes at multiple levels, we also asked whether an individual’s position on a behavioural syndrome is related to the role an individual takes within the colony (i.e. its caste). To answer these questions we first classified pers ...
... syndrome. Here, as part of our broader investigation into behavioural syndromes at multiple levels, we also asked whether an individual’s position on a behavioural syndrome is related to the role an individual takes within the colony (i.e. its caste). To answer these questions we first classified pers ...
The Very Young Patient - Advances in Inflammatory Bowel Diseases
... • Administrative database: Ontario 1994-2009 • Incidence increased 7.4%/year in age <6 ...
... • Administrative database: Ontario 1994-2009 • Incidence increased 7.4%/year in age <6 ...
Infections and the role of plasma proteins and platelets
... system are discussed in regard to the protective role of platelets and the reduction of the fungal load. In addition, possible negative effects of platelets are outlined which could be due to endocytosis of spores by platelets, followed by their transport through the body and protection of the patho ...
... system are discussed in regard to the protective role of platelets and the reduction of the fungal load. In addition, possible negative effects of platelets are outlined which could be due to endocytosis of spores by platelets, followed by their transport through the body and protection of the patho ...
Understanding the interaction between psychosocial stress
... Another latent virus, HIV-1, has been a focus for a number of studies in PNI. HIV-1 infection is an important model for understanding the potential impact of stressors on disease because immune and virologic processes that play a significant role in disease pathogenesis are known and easily accessibl ...
... Another latent virus, HIV-1, has been a focus for a number of studies in PNI. HIV-1 infection is an important model for understanding the potential impact of stressors on disease because immune and virologic processes that play a significant role in disease pathogenesis are known and easily accessibl ...
Community-wide body size differences between nocturnal and
... large insects are easier to see than smaller ones, birds may be more likely to target them during the day (Curio 1977, Berger et al. 2006). This pressure would be relaxed during the night, allowing increased activity of larger insects. Nightly drops in temperature, particularly at higher elevations, ...
... large insects are easier to see than smaller ones, birds may be more likely to target them during the day (Curio 1977, Berger et al. 2006). This pressure would be relaxed during the night, allowing increased activity of larger insects. Nightly drops in temperature, particularly at higher elevations, ...
Lung Host Defenses: A Status
... system must recognize and eliminate the many unwanted elements in inspired air such as particulates, noxious gases, microbes and other contaminants. This nonrespiratory activity of purifying inspired air and keeping lung tissues free of infection has been collectively termed "lung host-defense mecha ...
... system must recognize and eliminate the many unwanted elements in inspired air such as particulates, noxious gases, microbes and other contaminants. This nonrespiratory activity of purifying inspired air and keeping lung tissues free of infection has been collectively termed "lung host-defense mecha ...
Systemic features of immune recognition in the gut
... that allow subjugation of host cell machinery, other genes enable pathogenic agents to adhere to the epithelial cell wall. Enterohemorrhagic E. coli has been found to express an adherence factor called the E. coli common pilus (ECP). Pili are traditionally considered as virulence factors [46]; howev ...
... that allow subjugation of host cell machinery, other genes enable pathogenic agents to adhere to the epithelial cell wall. Enterohemorrhagic E. coli has been found to express an adherence factor called the E. coli common pilus (ECP). Pili are traditionally considered as virulence factors [46]; howev ...
Immune selection in neoplasia: towards a microevolutionary model
... occur, in which subclones with a survival or growth advantage come to predominate the tumour. This requires selective pressure. Competition for space, ability to recruit neovasculature and the ability to detach from neighbouring cells may all represent early selective pressures. Microevolutionary tu ...
... occur, in which subclones with a survival or growth advantage come to predominate the tumour. This requires selective pressure. Competition for space, ability to recruit neovasculature and the ability to detach from neighbouring cells may all represent early selective pressures. Microevolutionary tu ...
Implications of the behavioural immune system for social behaviour
... cues providing information about the potential benefits and potential costs of behavioural avoidance, and the psychological mechanisms underlying the avoidance strategy are activated or inhibited accordingly. The potential benefits of behavioural avoidance are most likely to accrue (and to outweigh ...
... cues providing information about the potential benefits and potential costs of behavioural avoidance, and the psychological mechanisms underlying the avoidance strategy are activated or inhibited accordingly. The potential benefits of behavioural avoidance are most likely to accrue (and to outweigh ...
Sp ec ia l R epo rt
... in reproductive decisions is adaptive. Ultimately, in-host and between-host processes also need to ...
... in reproductive decisions is adaptive. Ultimately, in-host and between-host processes also need to ...