What is a drug - William Ellis School
... Used to increase the amount of urine produced causing rapid weight loss in sports where performers are required to compete within strict weight boundaries, e.g. boxers or jockeys. Diuretics may also be taken in an attempt to reduce the concentration of any other banned substance that may be present ...
... Used to increase the amount of urine produced causing rapid weight loss in sports where performers are required to compete within strict weight boundaries, e.g. boxers or jockeys. Diuretics may also be taken in an attempt to reduce the concentration of any other banned substance that may be present ...
adrenergic drugs
... as few interruptions as possible. Avoid caffeine. Use sleep aids ( warm milk, back rub). For nasal decongestion – these drugs are contraindicated in those with high blood pressure and that overuse can increase in nasal congestion. ...
... as few interruptions as possible. Avoid caffeine. Use sleep aids ( warm milk, back rub). For nasal decongestion – these drugs are contraindicated in those with high blood pressure and that overuse can increase in nasal congestion. ...
Pharmacodynamics
... – Mostly damage to the function of liver, kidney, bone marrow and endocrine secretion ...
... – Mostly damage to the function of liver, kidney, bone marrow and endocrine secretion ...
Adrenergic and anti-adrenergic drugs
... ALPHA 1 ADRENERGIC BLOCKING AGENTS May activate reflexes that oppose fall in BP such as fluid retention and increased heart rate ´ Can prevent alpha medicated contraction of smooth muscle in nonvascular tissues ´ Thus, useful in treating BPH as inhibit contraction of muscles in prostate and bladder ...
... ALPHA 1 ADRENERGIC BLOCKING AGENTS May activate reflexes that oppose fall in BP such as fluid retention and increased heart rate ´ Can prevent alpha medicated contraction of smooth muscle in nonvascular tissues ´ Thus, useful in treating BPH as inhibit contraction of muscles in prostate and bladder ...
Sympathomimetic Drugs
... • Pancreatic b cells – inhibit insulin release (a 2 ) – stimulate insuline release (b 2) ...
... • Pancreatic b cells – inhibit insulin release (a 2 ) – stimulate insuline release (b 2) ...
2nd Lecture 1433
... bind To avoid constant activation of the receptor by promiscuous binding of many different ligands It must change its function upon binding in such a way that the function of the biologic system (cell, tissue, etc) is altered This is necessary for the ligand to cause a pharmacologic effect ...
... bind To avoid constant activation of the receptor by promiscuous binding of many different ligands It must change its function upon binding in such a way that the function of the biologic system (cell, tissue, etc) is altered This is necessary for the ligand to cause a pharmacologic effect ...
The receptors have a long extracellular domain
... In 1890 he was prescribed nitroglycerine (called trinitrin) to relieve the pain of angina attacks. It is still used today. Over 100 years later, the work of Robert Furchgott, Louis Ignarro and Ferid Murad showed that nitric oxide (NO) was an important signalling molecule in the cardiovascular system ...
... In 1890 he was prescribed nitroglycerine (called trinitrin) to relieve the pain of angina attacks. It is still used today. Over 100 years later, the work of Robert Furchgott, Louis Ignarro and Ferid Murad showed that nitric oxide (NO) was an important signalling molecule in the cardiovascular system ...
JNC_8-13120583 - Indian Association of Clinical Cardiologists
... Abundant evidence from randomized controlled trials(RCTs) has shown benefit of antihypertensive drug treatment in reducing important health outcomes in persons with hypertension Clinical guidelines are at intersection between research evidence & clinical actions that can improved patient outcomes Th ...
... Abundant evidence from randomized controlled trials(RCTs) has shown benefit of antihypertensive drug treatment in reducing important health outcomes in persons with hypertension Clinical guidelines are at intersection between research evidence & clinical actions that can improved patient outcomes Th ...
Chronotropic Effects of Select Cardiovascular Drugs on the
... drugs on the developing 4-chambered vertebrate heart using the embryonic chicken as the model system. Ninety percent of pregnant women take some type of drug: whether that is prescription, over-the-counter, or social in nature. The FDA has developed a grading rubric to rate a drug that may be used d ...
... drugs on the developing 4-chambered vertebrate heart using the embryonic chicken as the model system. Ninety percent of pregnant women take some type of drug: whether that is prescription, over-the-counter, or social in nature. The FDA has developed a grading rubric to rate a drug that may be used d ...
G-Protein Coupled Receptors Past, Present, Future Outline and
... Sir Henry Dale (Nobel Prize, 1936) At the Nobel lecture, speaking about acetylcholine which was isolated by his colleage Dr. Ewins in 1914. “I was thus able to describe it as having two apparently distinct types of action. Through what I termed its "muscarine" action, it reproduced at the periphery ...
... Sir Henry Dale (Nobel Prize, 1936) At the Nobel lecture, speaking about acetylcholine which was isolated by his colleage Dr. Ewins in 1914. “I was thus able to describe it as having two apparently distinct types of action. Through what I termed its "muscarine" action, it reproduced at the periphery ...
HTN - Ronna
... • You are rounding outside the room of Ned Flanders, a 75 yo man transferred out of the unit yesterday after a LGI bleed secondary to diverticulitis. He also has a hx of HTN, HLP, and renal cell CA in the distant past. The med student presents a BP of 162/88, and tells you ...
... • You are rounding outside the room of Ned Flanders, a 75 yo man transferred out of the unit yesterday after a LGI bleed secondary to diverticulitis. He also has a hx of HTN, HLP, and renal cell CA in the distant past. The med student presents a BP of 162/88, and tells you ...
Chronic Stable Angina
... ACCF/AHA/ACP/AATS/PCN/SCAT/STS guidelines βblockers and calcium channel blockers (CCBs), each alone or in combination, constitute medical therapy for relief of symptoms for chronic stable angina. However, combining nondihydropyridines (diltiazem and verapamil) with β-blockers should be avoided due ...
... ACCF/AHA/ACP/AATS/PCN/SCAT/STS guidelines βblockers and calcium channel blockers (CCBs), each alone or in combination, constitute medical therapy for relief of symptoms for chronic stable angina. However, combining nondihydropyridines (diltiazem and verapamil) with β-blockers should be avoided due ...
Dr Richard Stevenson
... Synthetic cannabinoids Isolated compounds Recreational problem identified in 2008/2009 Varying legal status ...
... Synthetic cannabinoids Isolated compounds Recreational problem identified in 2008/2009 Varying legal status ...
Drugs used to treat hypertension
... Note: Partial agonist activity (intrinsic sympathomimetic activity – ISA) - may be an advantage in treating patients with asthma because these drugs will cause bronchodilation; they have moderate (lower) effect on lipid metabolism, cause lesser vasospasms and negative inotropic effect. ...
... Note: Partial agonist activity (intrinsic sympathomimetic activity – ISA) - may be an advantage in treating patients with asthma because these drugs will cause bronchodilation; they have moderate (lower) effect on lipid metabolism, cause lesser vasospasms and negative inotropic effect. ...
The Use of Single Pill Combination Treatments in Patients
... including more than one dose of at least one (and often both) components. Hence the terms single-pill combination or flexible-dose combinations are preferred to the traditional meaning of FDCs. The use of FDC’s for the management of hypertension is limited in the UK, and much less commonly used than ...
... including more than one dose of at least one (and often both) components. Hence the terms single-pill combination or flexible-dose combinations are preferred to the traditional meaning of FDCs. The use of FDC’s for the management of hypertension is limited in the UK, and much less commonly used than ...
曹永孝
... Beta-receptor antagonists such as propranolol inhibit lipolysis. The effects on carbohydrate metabolism are less clear, but they should be used with caution in insulin-dependent diabetic patients. The chronic use of β-adrenoceptor antagonists has been associated with increased plasma VLDL and decrea ...
... Beta-receptor antagonists such as propranolol inhibit lipolysis. The effects on carbohydrate metabolism are less clear, but they should be used with caution in insulin-dependent diabetic patients. The chronic use of β-adrenoceptor antagonists has been associated with increased plasma VLDL and decrea ...
Document
... Dopamine Receptors • Dopamine receptors only activated by dopamine and not by any other adrenergic receptor agonist – D1: Muscle relaxation in vascular smooth muscles – D2: modulate neurotransmitter release ...
... Dopamine Receptors • Dopamine receptors only activated by dopamine and not by any other adrenergic receptor agonist – D1: Muscle relaxation in vascular smooth muscles – D2: modulate neurotransmitter release ...
Hypertension - Webstercare
... Angiotensin receptor blockers Angiotensin receptor blockers are also called sartans or angiotensin II antagonists. They also reduce vasoconstriction and sodium retention, but by a different mechanism to ACE inhibitors. ...
... Angiotensin receptor blockers Angiotensin receptor blockers are also called sartans or angiotensin II antagonists. They also reduce vasoconstriction and sodium retention, but by a different mechanism to ACE inhibitors. ...
Grade 2008-2010 final exam-A
... E. It can cause anaphylactic reaction 16. All of the following statements about cimetidine are true except A. An H2-receptor blocker B. used in peptic ulcer C. reduced the secretion of gastric acid D. little adverse reactions E. recurrence is rare after treatment is stopped 17. The patients with br ...
... E. It can cause anaphylactic reaction 16. All of the following statements about cimetidine are true except A. An H2-receptor blocker B. used in peptic ulcer C. reduced the secretion of gastric acid D. little adverse reactions E. recurrence is rare after treatment is stopped 17. The patients with br ...
Lecture 7 - Antidepressants new 11-12
... Serotonin Antagonists & Reuptake Inhibitors (SARIs) Trazodone Psychtropic drug Weak block of SERT > NET Block 5-HT2 α- blocking effect ( hypotension) Potent H1- blocker( sedation ) ...
... Serotonin Antagonists & Reuptake Inhibitors (SARIs) Trazodone Psychtropic drug Weak block of SERT > NET Block 5-HT2 α- blocking effect ( hypotension) Potent H1- blocker( sedation ) ...
Slide ()
... shifted to the right. Maximal responsiveness is preserved, however, because the remaining available receptors are still in excess of the number required. In curve C, produced after treatment with a larger concentration of antagonist, the available receptors are no longer “spare”; instead, they are j ...
... shifted to the right. Maximal responsiveness is preserved, however, because the remaining available receptors are still in excess of the number required. In curve C, produced after treatment with a larger concentration of antagonist, the available receptors are no longer “spare”; instead, they are j ...
Drug Discovery 3
... group of pharmaceutical chemists working at Pfizer's Sandwich, Kent research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a form of ischaemic cardiovascular disease). Phase I clinical trials under the direction of Ian Osterloh sugge ...
... group of pharmaceutical chemists working at Pfizer's Sandwich, Kent research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a form of ischaemic cardiovascular disease). Phase I clinical trials under the direction of Ian Osterloh sugge ...
Cardiovascular Therapeutics Watch Column
... Ongoing and future clinical research in this therapeutic area therefore continues to influence the choice of target BPs for various patient populations and treatment algorithms. Since non-adherence to behavioural interventions is equally as problematic as non-adherence to biopharmaceutical intervent ...
... Ongoing and future clinical research in this therapeutic area therefore continues to influence the choice of target BPs for various patient populations and treatment algorithms. Since non-adherence to behavioural interventions is equally as problematic as non-adherence to biopharmaceutical intervent ...
Centrally Acting Agents
... Methyldopa is incompletely absorbed after oral administration and undergoes extensive hepatic and pre-hepatic metabolism to form metabolites, some of which are active. The elimination halflife of the parent drug is about two hours. Moxonidine has pharmacokinetics very similar to those of clonidine b ...
... Methyldopa is incompletely absorbed after oral administration and undergoes extensive hepatic and pre-hepatic metabolism to form metabolites, some of which are active. The elimination halflife of the parent drug is about two hours. Moxonidine has pharmacokinetics very similar to those of clonidine b ...
Side Effects of Vasodilator Therapy
... conduction abnormalities such as sick sinus syndrome and heart block (W.A. Pettinger and H.C. Mitchell, unpublished observations). Because of the long duration of minoxidil's action, we have used this side effect to advantage in several patients. This potentially beneficial side effect should be sys ...
... conduction abnormalities such as sick sinus syndrome and heart block (W.A. Pettinger and H.C. Mitchell, unpublished observations). Because of the long duration of minoxidil's action, we have used this side effect to advantage in several patients. This potentially beneficial side effect should be sys ...