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Antiarrhythmic Drugs
Antiarrhythmic Drugs

... ectopic activity. Drugs have antiarrhythmic properties by virtue of their β -receptor–blocking action and direct membrane effects Some of these drugs have selectivity for cardiac β 1 receptors e.g. metoprolol, Some have intrinsic sympathomimetic activity e.g. pindolol. Some have marked direct membra ...
ANTI-PSYCHOTIC DRUGS
ANTI-PSYCHOTIC DRUGS

... MAO inhibitors (-) major degradation pathway resulting A. ...
Concentration-Effect Relationship of l
Concentration-Effect Relationship of l

... and Perrier, 1982). The pharmacokinetic parameters used to calculate the rate of infusion required for a given steady-state concentration were derived from Terao and Shen (1983) and Vermeulen et al. (1993). A 30 min (T) loading infusion was followed by a maintenance infusion over 2 hr and 20 min, fo ...
幻灯片 1
幻灯片 1

... JH, a 63-year-old architect, complains of urinary symptoms to his family physician. He has hypertension and the last 8 years, he has been adequately managed with a thiazide diuretic and an angiotensin-converting enzyme inhibitor. During the same period, JH developed the signs of benign prostatic hyp ...
Neurophar2016
Neurophar2016

... In the brain the main excitatory (depolarizing) transmitter is glutamate. Glutamate binds to several metabotropic and several ionotropic receptors. The main ionotropic receptor is the AMPA receptor. AMPA is an abbreviation of (±)-"-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid, obviously this ...
MUSCARINIC RECEPTOR ANTAGONISTS:
MUSCARINIC RECEPTOR ANTAGONISTS:

... Stupor and hallucinations (Criminally abused to render victims compliant) ...
N receptors
N receptors

... JH, a 63-year-old architect, complains of urinary symptoms to his family physician. He has hypertension and the last 8 years, he has been adequately managed with a thiazide diuretic and an angiotensin-converting enzyme inhibitor. During the same period, JH developed the signs of benign prostatic hyp ...
Lec 8
Lec 8

... • Drugs which are too polar or strongly ionized do not easily cross the cell membranes of the gut wall. Therefore, they are given by injection, but the disadvantage that they are quickly excreted. • Non-polar drugs, on the other hand, are poorly soluble in aqueous solution and are poorly absorbed. I ...
Congestive Heart Failure and Medical Therapy
Congestive Heart Failure and Medical Therapy

... (LASIX®, SALIX®). Other diuretics that are commonly used include spironolactone (ALDACTONE®), and hydrochlorothiazide (THIURETIC®, ESEDRIX®, HYDRODIURIL®). Diuretics are the most important medications an animal with acute congestive heart failure receives, and can save the life of a pet in a crisis. ...
Cardiovascular Diseases - Leslie Dan Faculty of Pharmacy
Cardiovascular Diseases - Leslie Dan Faculty of Pharmacy

... You should expect to spend a minimum of 3-5 hours outside of class per week preparing for lectures and workshops (more the week of workshops). Out of class preparation will include completing pre-readings disease states and completing additional readings related to specific group assigned learning o ...
Safety of the EP4 Receptor Antagonist, GRAPIPRANT
Safety of the EP4 Receptor Antagonist, GRAPIPRANT

... study, there were no treatment effects on liver or kidney function, or gross or histopathological findings of the liver, kidney, or stomach, or on coagulation parameters. The only histopathology of note was a mild mucosal regeneration of the ileum seen in one dog at 50 mg/kg. The relative lack of to ...
Adrenergic_antagonis..
Adrenergic_antagonis..

... It produces arterial & venous dilation. So it decreases BP, so it is used for the treatment of hypertension It causes less tachycardia than non–selective vasodilators (because it doesn’t act on α2 receptors) It precipitates less angina & cardiac arrhythmia It may increase HDL / cholesterol ratio. HD ...
Acute poisonings with substance of abuse
Acute poisonings with substance of abuse

... Management •In no way endoscopic removal of the package should be attempted. The patient in whom only one packet fails to pass the pylorus may be the exception •Conservative management during spontaneous evacuation of the containers is the first choice approach to the bodypacking •Surgery is indicat ...
Sedative-Hypnotic Drugs
Sedative-Hypnotic Drugs

... 1. Benzodiazepines: not to lead general anesthesia, raraly death. 2. Barbiturates: the older sedative-hypnotics, general depression of central nervous system. With such drugs, an increase in dose above that needed for hypnosis may lead to a state of general anesthesia. At still higher doses, it may ...
Pharmacy Technician*s Course. LaGuardia Community College
Pharmacy Technician*s Course. LaGuardia Community College

... Interaction 1: warfarin vs. many drugs. Warfarin or coumadin ® has many drug interactions. Critical ones involve NSAIDS like ibuprofen and diclofenac and aspirin. Other interaction involve herbals like gingko and garlic. These interaction increase the risk of fatal bleeding Interaction 2: ACE inhibi ...
FOM 2313 PHARMACOLOGY AND THERAPEUTICS
FOM 2313 PHARMACOLOGY AND THERAPEUTICS

... On completion of this course, students will be able to: 1. Apply conceptual knowledge about the drugs used in different systems of the body and their effects, to ensure safe administration and effective patient education. 2. Utilize knowledge of the expected and adverse reactions of medications base ...
Hypertension 2007` - Update on How to Choose and Prescribe the
Hypertension 2007` - Update on How to Choose and Prescribe the

... B. Beta-blockers C. Calcium channel blockers D. Diuretics For patients younger than 55, because of their stronger Renin- Angiotensin System (RAS), we can start with A (ARB or ACEI). C (calcium channel blockers) or D (diuretics) and will have a better result for patients older than 55 years old. A + ...
Thiazide and Thiazide
Thiazide and Thiazide

... thiazide-like diuretics were used in most of the early studies which established the benefit of treating hypertension albeit often at doses far in excess of those currently recommended. More recently, lowdose thiazides have often been included as add-on therapy in studies demonstrating outcome benef ...
Alpha-blockers in Renal Disease - Journal of the Association of
Alpha-blockers in Renal Disease - Journal of the Association of

... antihypertensives, α-blockers have demonstrated a good safety and efficacy profile as third line drugs. 9-11 The good lipid and glycaemic profile of α-blockers also favour their utility in patients with these comorbidities, which are commonly observed with CKD. In the ASCOT trial, addition of doxazo ...
What is schizophrenia
What is schizophrenia

... patient display sucking of the lips and other involuntary facial movement. (The dyskinesia may persist for after discontinuation of the therapy). ...
INSUFICIÊNCIA CARDÍACA
INSUFICIÊNCIA CARDÍACA

... MERIT-HF Study Group. Effect of Metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL randomized intervention trial in congestive heart failure (MERIT-HF). LANCET. 1999;353:2001-07. ...
A1980KP91000001
A1980KP91000001

... compounds became the standard of reference for all work done in the Roche Laboratories and in other pharmaceutical companies on this class of compounds, (3) neuroscientists became interested in the mechanism of action of compounds having such a broad range of pharmacological and clinical activity, ( ...
CCF_SL 2009 handouts
CCF_SL 2009 handouts

... • tachycardia • SLE (hydralazine) ...
Pharmacology of the autonomic nervous system for dental students
Pharmacology of the autonomic nervous system for dental students

... Precursor for the synthesis of acetylcholine is an amino acid, choline. Choline is taken up into the axon terminal by an active transport. Axonal mitochondria synthetize acetyl-CoA and with choline form acetylcholine. This reaction is catalysed by cholineacetylase enzyme. Acetylcholine is stored in ...
A1992HC31200002
A1992HC31200002

... actions of PCP upon multiple systems had been described, none of those systems could account forthe rankorders of potency of PCP derivatives in eliciting specific PCP-like animal behaviors. The first study employed the scientfffc approach which SRZ had learned as a medical student at Johns Hopkins U ...
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Discovery and development of beta-blockers

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