product information - cardizem® cd
... doses has resulted in embryo and foetal lethality. These doses, in some studies, have been reported to cause skeletal abnormalities. In the prenatal/postnatal studies there was some reduction in early individual pup weights and survival rates. There was an increased incidence of stillbirths at high ...
... doses has resulted in embryo and foetal lethality. These doses, in some studies, have been reported to cause skeletal abnormalities. In the prenatal/postnatal studies there was some reduction in early individual pup weights and survival rates. There was an increased incidence of stillbirths at high ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... The present study showed that there was no significant difference in the mode of delivery between two groups with a ‘P’ value of 0.365. But spontaneous vaginal delivery was more in the Labetalol group i.e. 28% . When compared to the Nifedipine group i.e. 14%. These results were more or less similar ...
... The present study showed that there was no significant difference in the mode of delivery between two groups with a ‘P’ value of 0.365. But spontaneous vaginal delivery was more in the Labetalol group i.e. 28% . When compared to the Nifedipine group i.e. 14%. These results were more or less similar ...
antihistamines in allergic disease
... *Two earlier developed agents, astemizole and terfenadine, were withdrawn in 1986 because of cardiac toxicity adverse effects. ...
... *Two earlier developed agents, astemizole and terfenadine, were withdrawn in 1986 because of cardiac toxicity adverse effects. ...
Treatment of Pulmonary Arterial Hypertension
... These agents are most useful in cor pulmonale, when left ventricular failure is also present.35 However, since neurohormonal sympathetic activation has been demonstrated in pulmonary hypertension, digoxin may be of value because of its sympatholytic properties.35,36 Digoxin may be most beneficial in ...
... These agents are most useful in cor pulmonale, when left ventricular failure is also present.35 However, since neurohormonal sympathetic activation has been demonstrated in pulmonary hypertension, digoxin may be of value because of its sympatholytic properties.35,36 Digoxin may be most beneficial in ...
A Descriptive Study of Adverse Events from
... FAACT, Director, Central Ohio Poison Center, Nationwide Children’s Hospital, 700 Children’s Drive, Columbus, OH 43205, USA. E-mail: [email protected] ...
... FAACT, Director, Central Ohio Poison Center, Nationwide Children’s Hospital, 700 Children’s Drive, Columbus, OH 43205, USA. E-mail: [email protected] ...
SERIES ‘‘PULMONARY HYPERTENSION: BASIC CONCEPTS FOR PRACTICAL MANAGEMENT’’
... A secondary end-point is also called a surrogate end-point [8]. These may be haemodynamic variables, blood biomarkers, imaging results, quality of life or others. Both the Food and Drug Administration (FDA) and the European Agency for the Evaluation of Medicinal Products (EMEA) permit the use of sur ...
... A secondary end-point is also called a surrogate end-point [8]. These may be haemodynamic variables, blood biomarkers, imaging results, quality of life or others. Both the Food and Drug Administration (FDA) and the European Agency for the Evaluation of Medicinal Products (EMEA) permit the use of sur ...
Acetylcholine-Activated Potassium Channel as a Novel Target for AF
... aged <60 years, but approximately 5% of those older than 65 years and about 8% of those older than 80 years are affected by AF (Furberg et al., 1994; Kannel et al., 1998). AF is not lethal arrhythmia but associated with an increased long-term risk of stroke, heart failure, and all-cause mortality (S ...
... aged <60 years, but approximately 5% of those older than 65 years and about 8% of those older than 80 years are affected by AF (Furberg et al., 1994; Kannel et al., 1998). AF is not lethal arrhythmia but associated with an increased long-term risk of stroke, heart failure, and all-cause mortality (S ...
this issue
... have been shown to maximize CV and renal protection in randomized controlled trials, currently believed to be between 140 and 130 mm Hg systolic and 90 to 80 mm Hg diastolic.2 How should CV and renal protection be established is a debated question, however. Several investigators, as well as virtuall ...
... have been shown to maximize CV and renal protection in randomized controlled trials, currently believed to be between 140 and 130 mm Hg systolic and 90 to 80 mm Hg diastolic.2 How should CV and renal protection be established is a debated question, however. Several investigators, as well as virtuall ...
Asif, M., 2015. Pharmacological activities and
... pattern type in which all mediators would come and go at the appropriate moment to play their roles in increasing vascular permeability, attracting leukocytes, producing pain, local oedema and necrosis, in which the predominance of any one would be fortuitous or depending on its specific capabilitie ...
... pattern type in which all mediators would come and go at the appropriate moment to play their roles in increasing vascular permeability, attracting leukocytes, producing pain, local oedema and necrosis, in which the predominance of any one would be fortuitous or depending on its specific capabilitie ...
Drug - University of Washington
... Absorption: absorbed from GI and rapidly hydrolyzed in intestinal mucosa and blood, take with food Distribution: widely distributed to most tissues and fluids including CSF (not used for meningitis, though) Metabolism: metabolized to free cefuroxime plus acetaldehyde and acetic acid Excretion: prima ...
... Absorption: absorbed from GI and rapidly hydrolyzed in intestinal mucosa and blood, take with food Distribution: widely distributed to most tissues and fluids including CSF (not used for meningitis, though) Metabolism: metabolized to free cefuroxime plus acetaldehyde and acetic acid Excretion: prima ...
Emerging options for the management of scorpion stings
... anti-inflammatory action, such as salicylates, mindful that use of salicylates could trigger Lyell’s syndrome or Reye’s syndrome, the latter occurring mostly in children during viral infections treated by salicylates.37 The incidence of Reye’s syndrome, the symptoms of which can be confused with wor ...
... anti-inflammatory action, such as salicylates, mindful that use of salicylates could trigger Lyell’s syndrome or Reye’s syndrome, the latter occurring mostly in children during viral infections treated by salicylates.37 The incidence of Reye’s syndrome, the symptoms of which can be confused with wor ...
glucocorticoid-induced hypertension and cardiac injury
... Corticosterone was reconstituted from a vial containing 500 mg of lyophilized powder with 1 mL of ethanol followed by 24 mL of polyethylene glycol 400 (Sigma) to yield a suspension of 20 mg/mL.16) Blood pressure measurement and echocardiographic analysis Systolic blood pressure (SBP) and heart rate ...
... Corticosterone was reconstituted from a vial containing 500 mg of lyophilized powder with 1 mL of ethanol followed by 24 mL of polyethylene glycol 400 (Sigma) to yield a suspension of 20 mg/mL.16) Blood pressure measurement and echocardiographic analysis Systolic blood pressure (SBP) and heart rate ...
View Prescribing Details
... Hydrochloride) binds selectively and competitively to postsynaptic Alpha1-adrenoreceptors, in particular to subtypes alpha1A and alpha1D. It brings about relaxation of Prostatic and urethral smooth muscle. Tamsulosin increases the maximum urinary flow rate. It relieves obstruction by relaxing smooth ...
... Hydrochloride) binds selectively and competitively to postsynaptic Alpha1-adrenoreceptors, in particular to subtypes alpha1A and alpha1D. It brings about relaxation of Prostatic and urethral smooth muscle. Tamsulosin increases the maximum urinary flow rate. It relieves obstruction by relaxing smooth ...
Chemical, pharmacokinetic and pharmacodynamic properties of
... triglyceride-rich lipoproteins [5,6]. In addition, statins may exert beneficial cardiovascular effects independent of their lipid-modifying properties [7]. These pleiotropic properties may be explained by inhibition of synthesis of nonsteroidal isoprenoid compounds, which are also produced from meva ...
... triglyceride-rich lipoproteins [5,6]. In addition, statins may exert beneficial cardiovascular effects independent of their lipid-modifying properties [7]. These pleiotropic properties may be explained by inhibition of synthesis of nonsteroidal isoprenoid compounds, which are also produced from meva ...
Effects of Antipsychotic Drugs on Extracellular Dopamine Levels in
... et al., 1997) which may be related to frontal lobe function. Thus, the greater ability of 5-HT2A/D2 receptor antagonists to increase extracellular DA levels in the cortical regions compared with subcortical regions may contribute to their ability to improve negative symptoms (Deutch et al., 1991). T ...
... et al., 1997) which may be related to frontal lobe function. Thus, the greater ability of 5-HT2A/D2 receptor antagonists to increase extracellular DA levels in the cortical regions compared with subcortical regions may contribute to their ability to improve negative symptoms (Deutch et al., 1991). T ...
beta-blockers
... catecholamines irritate the heart, causing an imbalance in supply and demand ratio and even leading to life-threatening dysrhythmias Beta Adrenergic Blockers block the harmful ...
... catecholamines irritate the heart, causing an imbalance in supply and demand ratio and even leading to life-threatening dysrhythmias Beta Adrenergic Blockers block the harmful ...
Knowledge Objectives
... fundamental toxicological principles are hybridized to underlie this aspect of toxicology. Nonetheless accidental poisoning with drugs is a health problem of major significance. More than 1/4 of the fatalities and about 1/2 of all poisonings occur in children under 5 years of age. All common househo ...
... fundamental toxicological principles are hybridized to underlie this aspect of toxicology. Nonetheless accidental poisoning with drugs is a health problem of major significance. More than 1/4 of the fatalities and about 1/2 of all poisonings occur in children under 5 years of age. All common househo ...
clinical pharmacology of a urotensin-II receptor antagonist in Type 2
... resistance is strongly associated with obesity and physical inactivity, and several mechanisms mediating this interaction have been identified. A number of circulating hormones, cytokines, and metabolic fuels, such as non-esterified (free) fatty acids (NEFA), originate in the adipocyte and modulate ...
... resistance is strongly associated with obesity and physical inactivity, and several mechanisms mediating this interaction have been identified. A number of circulating hormones, cytokines, and metabolic fuels, such as non-esterified (free) fatty acids (NEFA), originate in the adipocyte and modulate ...
100 Essential Drugs - University of Toledo
... I: used for Tx of CHF, A-V nodal depression (to control the ventricular response to paroxysmal supraventricular tachycardia) and atrial fibrillation or flutter UT: life-threatening cardiac arrhythmias ...
... I: used for Tx of CHF, A-V nodal depression (to control the ventricular response to paroxysmal supraventricular tachycardia) and atrial fibrillation or flutter UT: life-threatening cardiac arrhythmias ...
Chapter 19 - The Red Zone
... Nonselective beta-blockers may interfere with normal responses to hypoglycemia (tremor, tachycardia, nervousness) ...
... Nonselective beta-blockers may interfere with normal responses to hypoglycemia (tremor, tachycardia, nervousness) ...
Aldosterone and end-organ damage
... receptor; BP, blood pressure; BH4, 5,6,7,8-tetrahydrobiopterin; CHF, congestive heart failure; ECM, extracellular matrix; EGFR, epidermal growth factor receptor; ENaC, epithelial sodium channel; EPHESUS, Eplerenone Neurohormonal Efficacy and Survival; ET, endothelin; ETA , ET type A receptor; G6PD, ...
... receptor; BP, blood pressure; BH4, 5,6,7,8-tetrahydrobiopterin; CHF, congestive heart failure; ECM, extracellular matrix; EGFR, epidermal growth factor receptor; ENaC, epithelial sodium channel; EPHESUS, Eplerenone Neurohormonal Efficacy and Survival; ET, endothelin; ETA , ET type A receptor; G6PD, ...
Volume 50 Number 1
... Presidential Early Career Award for Scientists and Engineers (PECASE), the highest honor bestowed by the United States government on outstanding scientists and engineers beginning their independent careers. In addition to the clinical importance of her work for understanding multiple sclerosis and d ...
... Presidential Early Career Award for Scientists and Engineers (PECASE), the highest honor bestowed by the United States government on outstanding scientists and engineers beginning their independent careers. In addition to the clinical importance of her work for understanding multiple sclerosis and d ...
Volume 48 Number 4
... ASPET continues its leading advocacy to increase training for integrative organ systems pharmacology. ASPET is also committed to making significant contributions through its new affiliation with The FDA Alliance to increase funding for the agency, and as always, we are continuing to work in partners ...
... ASPET continues its leading advocacy to increase training for integrative organ systems pharmacology. ASPET is also committed to making significant contributions through its new affiliation with The FDA Alliance to increase funding for the agency, and as always, we are continuing to work in partners ...
Management of Hypertension - Kementerian Kesihatan Malaysia
... CCBs, diuretics and beta blockers. Beta blockers is now recommended based on evidence from newer meta analyses since the last edition. ...
... CCBs, diuretics and beta blockers. Beta blockers is now recommended based on evidence from newer meta analyses since the last edition. ...