Diseases of the Vagina Azza AlYamani Prof. Obstet
... * the risk for developing a clear cell adenocarcinoma following DES exposure in utero is only 1/1000 . * the mean age is 19 years, rare before 14y. few cases reported in women in their 40s & 50s. ...
... * the risk for developing a clear cell adenocarcinoma following DES exposure in utero is only 1/1000 . * the mean age is 19 years, rare before 14y. few cases reported in women in their 40s & 50s. ...
Bronchial Pleomorphic Adenoma Coexisting with Lung Cancer
... Pleomorphic adenoma, which is the most common tumor of the major salivary glands,2) occurs in the lung and typically arises from the tracheal and bronchial seromucous glands.3) These tumors are extremely rare, and their incidence, etiology and prognosis are unknown.4) Only 35 cases of tracheobronchi ...
... Pleomorphic adenoma, which is the most common tumor of the major salivary glands,2) occurs in the lung and typically arises from the tracheal and bronchial seromucous glands.3) These tumors are extremely rare, and their incidence, etiology and prognosis are unknown.4) Only 35 cases of tracheobronchi ...
`phase 2` cancer survival benchmark
... ICBP analyses, using a novel method (Walters et al, 2013a) of comparing international survival with routinely collected stage at diagnosis, reveal a complex picture across partners for ovarian, colorectal, lung and breast cancers (Maringe et al, 2012; Maringe et al, 2013; Walters et al, 2013b; Walt ...
... ICBP analyses, using a novel method (Walters et al, 2013a) of comparing international survival with routinely collected stage at diagnosis, reveal a complex picture across partners for ovarian, colorectal, lung and breast cancers (Maringe et al, 2012; Maringe et al, 2013; Walters et al, 2013b; Walt ...
Comprehensive molecular characterization of gastric adenocarcinoma
... We analysed the patterns of base changes within gastric cancer tumours and noted elevated rates of C to T transitions at CpG dinucleotides. We observed an elevated rate of A to C transversions at the 39 adenine of AA dinucleotides, especially at AAG trinucleotides, as reported in oesophageal adenoca ...
... We analysed the patterns of base changes within gastric cancer tumours and noted elevated rates of C to T transitions at CpG dinucleotides. We observed an elevated rate of A to C transversions at the 39 adenine of AA dinucleotides, especially at AAG trinucleotides, as reported in oesophageal adenoca ...
Integrating next-generation sequencing into clinical oncology
... drugs from 1998 to 2013, the use of a personalised strategy was independently associated with higher response rates and improved progression-free and overall survival.33 However, the findings of the SHIVA trial underline the need for a better characterisation of molecular drivers before assigning pat ...
... drugs from 1998 to 2013, the use of a personalised strategy was independently associated with higher response rates and improved progression-free and overall survival.33 However, the findings of the SHIVA trial underline the need for a better characterisation of molecular drivers before assigning pat ...
+ ___ Other (specify) - College of American Pathologists
... © 2016 College of American Pathologists (CAP). All rights reserved. The College does not permit reproduction of any substantial portion of these protocols without its written authorization. The College hereby authorizes use of these protocols by physicians and other health care providers in reportin ...
... © 2016 College of American Pathologists (CAP). All rights reserved. The College does not permit reproduction of any substantial portion of these protocols without its written authorization. The College hereby authorizes use of these protocols by physicians and other health care providers in reportin ...
Appendix C - CCO Staging Guidelines 2005-10-14
... The required data elements will be collected for all adult patients6 with cancer, at the time of diagnosis7, and reported to Cancer Care Ontario in keeping with the Collaborative Staging Manual and the CCO Data Book. In accordance with CCO policies on data use and disclosure, staging information wil ...
... The required data elements will be collected for all adult patients6 with cancer, at the time of diagnosis7, and reported to Cancer Care Ontario in keeping with the Collaborative Staging Manual and the CCO Data Book. In accordance with CCO policies on data use and disclosure, staging information wil ...
RESEARCH ARTICLE Tumor Diameter for Prediction of Recurrence
... survival and overall survival. Results: In ROC analyses tumor diameter was a significant predictor of recurrence (AUC:0.771, P<0.001). The optimal cut off value was 3.75 with 82% sensitivity and 63% specificity. In correlation analyses tumor grade (r=0.267, p=0.001), tumor diameter (r=0.297, p<0.001 ...
... survival and overall survival. Results: In ROC analyses tumor diameter was a significant predictor of recurrence (AUC:0.771, P<0.001). The optimal cut off value was 3.75 with 82% sensitivity and 63% specificity. In correlation analyses tumor grade (r=0.267, p=0.001), tumor diameter (r=0.297, p<0.001 ...
Operator Dependent Choice of Prostate Cancer
... The Gleason Score (GS) grading system is the dominant histopathological grading method for prostatic carcinoma around the world, both in research and in clinical routine. Gleason score is the sum of the Gleason grades of the most common and the second most common tumor patterns. GS is one of the mos ...
... The Gleason Score (GS) grading system is the dominant histopathological grading method for prostatic carcinoma around the world, both in research and in clinical routine. Gleason score is the sum of the Gleason grades of the most common and the second most common tumor patterns. GS is one of the mos ...
Diagnosis of uncertain primary tumors with the Pathwork® tissue
... classifying tumors based on their TOO and exploring the computing algorithms that were best suited for this purpose. Su and coworkers used supervised machine-learning algorithms to generate a tissue classifier based on a 110 mRNA transcript profile that showed 85% accuracy in classifying samples from ...
... classifying tumors based on their TOO and exploring the computing algorithms that were best suited for this purpose. Su and coworkers used supervised machine-learning algorithms to generate a tissue classifier based on a 110 mRNA transcript profile that showed 85% accuracy in classifying samples from ...
What Is the Appropriate Clinical Target Volume for Esophageal
... (PTV) margins in this study appeared adequate. Interestingly, only 3 patients relapsed in regions adjacent to the RT fields. To improve local control, it seems that larger field margins would unlikely have been clinically effective in these cases. The results of Gao et al. [25], who studied the CTVp ...
... (PTV) margins in this study appeared adequate. Interestingly, only 3 patients relapsed in regions adjacent to the RT fields. To improve local control, it seems that larger field margins would unlikely have been clinically effective in these cases. The results of Gao et al. [25], who studied the CTVp ...
Report on EU-USA Workshop: How Systems Biology Can Advance
... approaches, and should be strongly encouraged. The systems view of disease combined with these new technologies and novel computational tools will over the next 5–20 years lead to medicine that is predictive, personalized, preventive and participatory (P4 medicine). Major initiatives are in progress ...
... approaches, and should be strongly encouraged. The systems view of disease combined with these new technologies and novel computational tools will over the next 5–20 years lead to medicine that is predictive, personalized, preventive and participatory (P4 medicine). Major initiatives are in progress ...
Boot Camp 2014 Quiz Answers
... Lytic lesion within the left mandibular ramus measuring 8 mm by 5 mm and may have slightly increased in size since prior exam 6/10/13. There is another 5 mm lytic lesion within the symphysial region of the mandible which is new. There is soft tissue air seen in the left sublingual region. 7/13/13 Di ...
... Lytic lesion within the left mandibular ramus measuring 8 mm by 5 mm and may have slightly increased in size since prior exam 6/10/13. There is another 5 mm lytic lesion within the symphysial region of the mandible which is new. There is soft tissue air seen in the left sublingual region. 7/13/13 Di ...
A Case Report of Solitary Adrenal Metastasis from Early Stage
... which are often preceded by premalignant disease and express the oestrogen receptor and progesterone receptor.2 Furthermore, they are predominantly low grade and rarely metastasise. The prognosis of type I cancers are favourable if diagnosed at an early stage, with a 5 year survival of >97% in stage ...
... which are often preceded by premalignant disease and express the oestrogen receptor and progesterone receptor.2 Furthermore, they are predominantly low grade and rarely metastasise. The prognosis of type I cancers are favourable if diagnosed at an early stage, with a 5 year survival of >97% in stage ...
Protocol for the Examination of Specimens From Patients With
... The College does not permit reproduction of any substantial portion of these protocols without its written authorization. The College hereby authorizes use of these protocols by physicians and other health care providers in reporting on surgical specimens, in teaching, and in carrying out medical re ...
... The College does not permit reproduction of any substantial portion of these protocols without its written authorization. The College hereby authorizes use of these protocols by physicians and other health care providers in reporting on surgical specimens, in teaching, and in carrying out medical re ...
Protocol S1.
... reference set of normal samples. In the case of the 10K array, this reference set contained 31 samples taken from the bone marrow transplant study described above. In the case of the 11K array, this reference set contained 31 samples. Twenty-three of these were normal control data previously publish ...
... reference set of normal samples. In the case of the 10K array, this reference set contained 31 samples taken from the bone marrow transplant study described above. In the case of the 11K array, this reference set contained 31 samples. Twenty-three of these were normal control data previously publish ...
Solid Tumour Section Penile tumors: an overview Atlas of Genetics and Cytogenetics
... oncogenic protein in cells. There is also evidence that overexpression of MDM2 is important in aberrant P53 down-regulation in penile cancer (Ouban et al., 2003). There is no evidence of correlation with grade or stage of disease. In multivariate analysis P53 was assessed as an independent prognosti ...
... oncogenic protein in cells. There is also evidence that overexpression of MDM2 is important in aberrant P53 down-regulation in penile cancer (Ouban et al., 2003). There is no evidence of correlation with grade or stage of disease. In multivariate analysis P53 was assessed as an independent prognosti ...
nci comprehensive cancer centers - MSK Library
... ▪ Most are affiliated with university medical centers, while others are freestanding centers focused only on cancer research ▪ Mission for all centers typically include: ▪ Cancer research that spans laboratory science, clinical research, and population-based research ▪ Clinical programs that offer t ...
... ▪ Most are affiliated with university medical centers, while others are freestanding centers focused only on cancer research ▪ Mission for all centers typically include: ▪ Cancer research that spans laboratory science, clinical research, and population-based research ▪ Clinical programs that offer t ...
Cancer Diagnosis
... Generally liver and renal disease as well as inflammation and infection may cause elevated tumor marker concentrations. Benign diseases of tumor marker producing tissues also frequently cause elevated concentrations. ...
... Generally liver and renal disease as well as inflammation and infection may cause elevated tumor marker concentrations. Benign diseases of tumor marker producing tissues also frequently cause elevated concentrations. ...
Gastrointestinal Adenocarcinomas of the
... neoplastic process, and (ii) identifying the specific genes that mediate tumor progression. Both challenges must be confronted in analysis of somatic copy-number alterations (SCNA) as tumors often harbor many such alterations, each of which often encompasses up to thousands of genes. The study of SCN ...
... neoplastic process, and (ii) identifying the specific genes that mediate tumor progression. Both challenges must be confronted in analysis of somatic copy-number alterations (SCNA) as tumors often harbor many such alterations, each of which often encompasses up to thousands of genes. The study of SCN ...
PowerPoint slides - Research To Practice
... in patients with BRCA mutation-negative HGSOC. The activity observed with this agent in BRCA germline mutation carriers and ovarian cancer confirms previous studies. Olaparib was well tolerated in both ovarian and breast cancer patient populations with a side-effect profile similar to those in previ ...
... in patients with BRCA mutation-negative HGSOC. The activity observed with this agent in BRCA germline mutation carriers and ovarian cancer confirms previous studies. Olaparib was well tolerated in both ovarian and breast cancer patient populations with a side-effect profile similar to those in previ ...
The Prognostic Value of Circulating Cell-Free
... monitoring and survival prediction of colorectal cancer (CRC). However, its prognostic significance for patients with CRC remains controversial. To derive a precise estimation of the prognostic significance of cfDNA, a meta-analysis was performed. Methods: We made a systematic search in data base of ...
... monitoring and survival prediction of colorectal cancer (CRC). However, its prognostic significance for patients with CRC remains controversial. To derive a precise estimation of the prognostic significance of cfDNA, a meta-analysis was performed. Methods: We made a systematic search in data base of ...
NCCN - Management of Thyroid Carcinoma -2001
... Thyroid Neoplasms David R. Byrd, MD Department of Surgery University of Washington ...
... Thyroid Neoplasms David R. Byrd, MD Department of Surgery University of Washington ...
title page title: “metastasis of ovarian cancer to breast: the
... cancer and showed that WT-1 positivity is positively correlated with high grade, advanced stage and higher Ki-67 index, higher bcl-2 expression and poorer outcome in a study. Although WT-1 positivity can be seen in many solid tumours, it has been identified as a possible marker mostly for ovarian ca ...
... cancer and showed that WT-1 positivity is positively correlated with high grade, advanced stage and higher Ki-67 index, higher bcl-2 expression and poorer outcome in a study. Although WT-1 positivity can be seen in many solid tumours, it has been identified as a possible marker mostly for ovarian ca ...
Solid Tumour Section Vulva and Vagina tumors: an overview
... Vulva. As with many other types of cancer prognosis depends on several factors, including the histological type of the lesion. In general, patients with increasing tumor stage have a lower rate of survival. The overall 5-year survival rate ranges from 90% to 33%, depending upon whether and how many ...
... Vulva. As with many other types of cancer prognosis depends on several factors, including the histological type of the lesion. In general, patients with increasing tumor stage have a lower rate of survival. The overall 5-year survival rate ranges from 90% to 33%, depending upon whether and how many ...