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Artificial Immune Systems: An Emerging Technology
Artificial Immune Systems: An Emerging Technology

... A robust system should detect any foreign activity rather than looking for specific known patterns of intrusion. No prior knowledge of anomaly (non-self) is required The size of the detector set does not necessarily increase with the number of strings being protected The detection probability increa ...
Probiotics for the Immune System
Probiotics for the Immune System

... Exact dosages can’t be found on most products, but foods and supplements will list the species and strain. Some will state that the cultures are live and active, and supplements will list the approximate number of cultures. In 2011, the Agency for Healthcare Research and Quality looked at the safety ...
Poster: MenBioVax generates cross strain immunogenicity
Poster: MenBioVax generates cross strain immunogenicity

... America, no broadly effective vaccine has been approved. This is due in part to the low immunogenicity of the serogroup B capsular polysaccharide. ...
Guidelines for the Control of Hepatitis A
Guidelines for the Control of Hepatitis A

... The global epidemiology of hepatitis A has changed markedly due to improvements in water supply, sanitation and hygiene. In highly industrialised countries prevalence in blood donors is now <10% and ...
Prevention of Hepatitis A with the Hepatitis A Vaccine
Prevention of Hepatitis A with the Hepatitis A Vaccine

... and routine childhood immunization against hepatitis A was recommended in the identified communities. The intent was to reduce the rates of hepatitis A infection and disease among immunized children and — because children had been the primary sources of the spread of hepatitis A virus in these setti ...
Childrens infectious diseases
Childrens infectious diseases

... D. *In the period of pigmentation E. In the period of recovery 32.Indicate the features of measles pigmentation spreading. A. Begins from lower extremities, staging spreads farther B. At the same time appears all over the body C. Begins from a trunk, spreads staging on the face, extremities D. A ras ...
Shingles - Children`s Hospital of Philadelphia
Shingles - Children`s Hospital of Philadelphia

... Q. Is shingles contagious? A. Yes. Although people with shingles cannot give someone else shingles, they can pass the chickenpox virus to others through direct contact with the rash. So if, for example, the grandchildren of someone with shingles have not yet had chickenpox or the chickenpox vaccine, ...
press kit - Sanofi Pasteur
press kit - Sanofi Pasteur

... Sanofi Pasteur’s vaccine candidate safely protects pre-adolescents to adults against dengue in endemic countries. In December 2015, Sanofi Pasteur’s dengue vaccine was approved in Mexico, making it the first vaccine to be licensed in the world for active immunization against dengue disease in preado ...
Varicella (Chickenpox) and Herpes Zoster (Shingles): Healthcare Professionals
Varicella (Chickenpox) and Herpes Zoster (Shingles): Healthcare Professionals

... • Two live attenuated varicella virus vaccines licensed for use in US: Varivax® and Proquad® • Both vaccines may be used for first and second doses of varicella vaccine • Varivax ® (1,400 pfu) is the single-antigen varicella vaccine licensed in 1995 for use among healthy persons aged ≥ 12 months • P ...
II. Infection Control Measures
II. Infection Control Measures

... polysaccharide vaccine (PPV23) and Td vaccination for residents. o Include Vaccine Information Statements (VIS) for pneumococcal, Td and influenza vaccines in the admission packet. VISs in many languages are available online at www.immunize.org/vis and from MDPH. Obtain consent for vaccination from ...
A
A

... Before introduction of the varicella vaccination, almost every child developed chickenpox.14 Since the introduction of the childhood vaccine in the US in 1995, there has been an 88% decrease in hospitalizations due to chickenpox. It is estimated that $84.9 million was spent in the US from 1994 to 1 ...
PDF
PDF

... are exogenous to human choices, we assume some parameters are endogenous functions of the supplemental feeding choice, f. Specifically, natural mortality is assumed to be declining in f. We model this as M ( f ) = m(1 − wf ) , where m is the natural mortality rate and w is a parameter that represent ...
Distinct cytokine profiles define clinical immune response to
Distinct cytokine profiles define clinical immune response to

... humoral and cell-mediated immune responses, and their acquisition of clinical immunity, may be a consequence of their relative exposure to parasite infection. Populations living in malaria-endemic areas develop acquired immunity against severe malaria as a result of repeated infection and accumulati ...
Volume XV No. VI November/December 2012
Volume XV No. VI November/December 2012

... What are the recommended doses for RV and HRIG? Are the pediatric and adult doses the same? Can these products be used in pregnant women? The dosage recommendations for pre-exposure and post-exposure vaccination with RabAvert® and Imovax® Rabies are the same for all age groups; infants and children ...
Rotarix - GlaxoSmithKline
Rotarix - GlaxoSmithKline

... Excretion of the vaccine virus in the stools is known to occur after vaccination and lasts for 10 days on average with peak excretion around the 7th day. Viral antigen particles detected by ELISA were found in 50% (at day 7) of stools after the first dose and 17.4% (at day 3) and 4% (at day 7) of st ...
Helicobacter pylori vaccines and mechanisms of effective
Helicobacter pylori vaccines and mechanisms of effective

... immunity. Even before animal models became available, Czinn and Nedrud found that immunization of mice and ferrets with killed H. pylori and CT produced a significant intestinal and serum antibody response.22 When the H. felis mouse model was developed and protective immunity demonstrated,23 it was ...
Pigs immunized with Chinese highly pathogenic PRRS virus
Pigs immunized with Chinese highly pathogenic PRRS virus

... Modified live virus (MLV) vaccines developed to protect against PRRSV circulating in North America (NA) offer limited protection to highly pathogenic (HP) PRRSV strains that are emerging in Asia. MLV vaccines specific to HP-PRRSV strains commercially available in China provide protection to HP-PRRSV; ...
Invasive Group B Streptococcal Disease: The Emergence of
Invasive Group B Streptococcal Disease: The Emergence of

... period was unchanged from that in 1989-1990. It remains to be determined whether recently published strategies (i.e., intrapartum chemoprophylaxis of high-risk maternal carriers) to prevent infection of the neonate [1, 24, 25] will influence rates of neonatal infection in metropolitan Atlanta. A sur ...
Measles (Rubeola) Disease Report
Measles (Rubeola) Disease Report

... Molecular Analysis can also be completed. Genotyping is used to map the transmission pathways of measles viruses. The genetic data can help to link or unlink cases and can suggest a source for imported cases. “Genotyping is the only way to distinguish between wild-type measles virus infection and ...
Beta-Glucan - Human Nature Natural Health
Beta-Glucan - Human Nature Natural Health

... over a multi-day period, providing a unique mechanism of action for the beta-glucan form found in Beta-Glucan Plus Maitake. Studies also indicate that the entrance of these soluble fragments into the bone marrow may affect whiteblood–cell recovery, further enhancing its health effects.[13] Individua ...
The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent
The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent

... (IFNs). Stimulator of IFN genes (STING) has been identified as a central adaptor protein mediating intracellular signaling events in response to cytosolic DNA, by directing the activation of the transcription factors, nuclear factor kappa B (NF-kB) and interferon regulatory factor 3 (IRF3) through t ...
Inflammation and oxidative stress in vertebrate host–parasite systems
Inflammation and oxidative stress in vertebrate host–parasite systems

... pathogens very shortly after the encounter between inflammatory cells and the intruder, but in a nonspecific way. Owing to this non-specific response, inflammation can generate substantial costs for the host if the inflammatory response, and the associated oxygen-based damage, get out of control. Th ...
TITLE: A Multicenter, Randomized Dose Response Study of
TITLE: A Multicenter, Randomized Dose Response Study of

... vaccine (Dryvax) administered to children in the event there is a smallpox terrorist event. The objective of this study is to evaluate the safety and the rate of clinical and immune responses with stockpiled Dryvax vaccine when administered to children 2 -5 years of age. It will be evaluated undilu ...
2006 Feline Vaccine Guidelines - American Association of Feline
2006 Feline Vaccine Guidelines - American Association of Feline

... Kittens are generally more susceptible to infection and typically develop more severe diseases than adult cats. Thus, kittens represent the principal target population for vaccination. As part of a routine health care program, the vaccination needs of all cats, including adults, should be assessed a ...
Sydney Arthur Monckton Copeman (1862-1947)
Sydney Arthur Monckton Copeman (1862-1947)

... A noteworthy inoculator was Thomas Dimsdale, M.D. (1712-1800), King's College, Aberdeen, and Estra-Licentiate of the College of Physicians, London. After serving as a surgeon in the '45, he went into practice and in 1767 published a book on The Present Method of Inoculating for the Smallpox, which h ...
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Herd immunity



Herd immunity (also called herd effect, community immunity, population immunity, or social immunity) is a form of indirect protection from infectious disease that occurs when a large percentage of a population has become immune to an infection, thereby providing a measure of protection for individuals who are not immune. In a population in which a large number of individuals are immune, chains of infection are likely to be disrupted, which stops or slows the spread of disease. The greater the proportion of individuals in a community who are immune, the smaller the probability that those who are not immune will come into contact with an infectious individual.Individual immunity can be gained through recovering from a natural infection or through artificial means such as vaccination. Some individuals cannot become immune due to medical reasons and in this group herd immunity is an important method of protection. Once a certain threshold has been reached, herd immunity will gradually eliminate a disease from a population. This elimination, if achieved worldwide, may result in the permanent reduction in the number of infections to zero, called eradication. This method was used for the eradication of smallpox in 1977 and for the regional elimination of other diseases. Herd immunity does not apply to all diseases, just those that are contagious, meaning that they can be transmitted from one individual to another. Tetanus, for example, is infectious but not contagious, so herd immunity does not apply.The term herd immunity was first used in 1923. It was recognized as a naturally occurring phenomenon in the 1930s when it was observed that after a significant number of children had become immune to measles, the number of new infections temporarily decreased, including among susceptible children. Mass vaccination to induce herd immunity has since become common and proved successful in preventing the spread of many infectious diseases. Opposition to vaccination has posed a challenge to herd immunity, allowing preventable diseases to persist in or return to communities that have inadequate vaccination rates.
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