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84 yo woman with a cough: epidemiologic implications
84 yo woman with a cough: epidemiologic implications

... was licensed for vaccination in persons between the ages of 10 – 18. • In June, 2005, Adacel (Sanofi-Aventis) was licensed for use in person between 11 – 64 years. • Both vaccines are Tdap vaccines which contains tetanus, diphtheria and acellular pertussis. MMWR 2005; 54 (50) ...
Human Papilloma Virus 2017
Human Papilloma Virus 2017

... *In a 2-dose schedule of HPV vaccine, the minimum interval between the first and second doses is 5 months. ** In a 3-dose schedule of HPV vaccine, the minimum intervals are 4 weeks between the first and second doses, 12 weeks between the second and third doses, and 5 months between the first and thi ...
Measuring Cellular Immunity to Influenza: Methods of Detection
Measuring Cellular Immunity to Influenza: Methods of Detection

... Received: 13 February 2015 / Accepted: 30 March 2015 / Published: 14 April 2015 ...
Incubation temperature affects multiple
Incubation temperature affects multiple

... incubation periods had weaker swelling responses than birds with shorter incubation periods [9]. However, our results are inconsistent with the detected negative relationship between malaria prevalence and incubation period across 36 altricial bird species [10], and thus do not support the hypothesi ...
PDF printable version of 3.3 Groups with special vaccination
PDF printable version of 3.3 Groups with special vaccination

... infectious diseases, even in the absence of specific immune defects, for example, the use of influenza and pneumococcal vaccines in individuals with an increased risk of complications from these diseases. The presence of additional recommendations specific to groups discussed in this section underpi ...
Maggini S et al. Selected vitamins and trace elements support
Maggini S et al. Selected vitamins and trace elements support

... stomach. Adaptive immunity is the second barrier to infection and is acquired later in life, such as after an immunization or successfully fighting off an infection. It retains a memory of all the invaders it has faced and this accelerates antibody production. Although defence mechanisms of innate a ...
Measles - NSW Health
Measles - NSW Health

... of endemic transmission in a defined geographical area for ≥ 12months.(1) Although measles is no longer endemic here, Australia continues to have imported cases in overseas visitors and returning residents, with the potential for limited transmission and small to moderate-sized outbreaks. Geographic ...
Human Disease Ch 2
Human Disease Ch 2

... Chapter 2 Immunity and the Lymphatic System ...
Evolutionary insights into the origin of innate and adaptive immune
Evolutionary insights into the origin of innate and adaptive immune

... example, IgM1gj. Another unique primordial Ig isotype found in cartilaginous fish and in some bony fish is IgW.10,11 The structure of the IgW in shark in particular has large variation. For example, the number of C domain varies from as few as 2 to as high as 6. The IgW isotype appears to be phyloge ...
Meningococcal Disease Information and Investigation Guidelines Table of Contents:
Meningococcal Disease Information and Investigation Guidelines Table of Contents:

... CSF from a lumbar puncture (LP or spinal tap) in conjunction with a blood isolate are the primary specimens used to diagnose meningococcal disease. Unless contraindicated, a lumbar puncture and blood sample should be taken immediately prior, or concurrently to starting antibiotic therapy. CSF and bl ...
Shingles vaccine (Zostavax®) PGD template
Shingles vaccine (Zostavax®) PGD template

... ≤3.0mg/kg/day or 6-mercaptopurine ≤1.5mg/kg/day) are not considered sufficiently immunosuppressive and these individuals can receive the vaccine under this PGD unless they also have impaired renal function (see above). Temporary exclusions are:  acute severe febrile illness – postpone administratio ...
immune system - Bio-Inspired Artificial Intelligence
immune system - Bio-Inspired Artificial Intelligence

... receptors (TCRs). When activated they are in charge of: – Killing cells that display antigens they recognize – Activating the elements that work in the “analog” modality – Become memory T-cells Companion slides for the book Bio-Inspired Artificial Intelligence: Theories, Methods, and Technologies by ...
What We Learn About Smallpox from Movies - Fact
What We Learn About Smallpox from Movies - Fact

... In movies and television programs, a single infectious person may be shown infecting many people. In the movie Smallpox, the terrorist infected approximately 20 other people, who then infected twenty others, and so on, so that the subsequent infection rate was too great to contain. Fact: Smallpox is ...
recurrent herpes zoster in an immunocompetent adult male
recurrent herpes zoster in an immunocompetent adult male

... herpesvirus causes chicken pox and then remains latent for decades in cranial nerve, dorsal root and autonomic nervous system ganglia.1 The virus gets reactivated after a variable period of time usually ranging from 5-40 years2 in 15% patients3 and causes herpes zoster. Herpes zoster is a painful, d ...
Serologic Analysis of the IgG Antibody Response in
Serologic Analysis of the IgG Antibody Response in

... in Germany. Initially, given as a single dose, this recommendation was modified in favor of a 2-dose regimen in Germany by 2009.1–3 In contrast to VZV wild-type infection, which typically confers lifelong immunity, breakthrough infections can occur months to years after VZV immunization and are caus ...
Use of 9-Valent Human Papillomavirus (HPV) Vaccine: Updated
Use of 9-Valent Human Papillomavirus (HPV) Vaccine: Updated

... neoplasia grade 2 or 3 caused by HPV 31, 33, 45, 52, or 58 was 96.7% in the per protocol population* (Table 2) (2,16). Efficacy for prevention of ≥CIN2 caused by HPV 31, 33, 45, 52, or 58 was 96.3% and for 6-month persistent infection was 96.0% (16). Few cases were caused by HPV 6, 11, 16, or 18 in ...
Here - Vanderbilt University
Here - Vanderbilt University

... destruction by the cibarial armature.27 This barrier, composed of sclerotized teeth and spines that protrude into the lumen of the foregut, slices large pathogens during the initial stages of ingestion and before they reach the midgut. The cibarial armature is effective in limiting infection by larg ...
A - Personal.psu.edu
A - Personal.psu.edu

... the scientific community due to its ramifications on human health. The disease caused by B. pertussis, whooping cough, is an acute, severe coughing illness that can progress to become spasmodic. Extreme cases may lead to regurgitation, convulsions, collapse, coma, and death (3). A closely related me ...
HPV Vaccine Introduction - Demo Project in Zim
HPV Vaccine Introduction - Demo Project in Zim

... and to be intensified as from 4th quarter 13  Two demonstration project districts have been identified-Marondera and Beitbridge  Need for TA (HQ,AFRO,IST) support in planning, implementation, monitoring and evaluation ...
WCIT 2010-Invitation Letter1
WCIT 2010-Invitation Letter1

... Dear Friends and Colleagues, We extend a warm welcome to the leading scientists, doctors, industrialists and young researchers to BIT Life Sciences’ 1st Annual World Congress of Immunodiseases and Therapy 2010 (WCIT-2010) with the theme of “Boosting Health and Vitality”, which will take place in Bei ...
Natural Defenses– Strengthening Your Immune System Against
Natural Defenses– Strengthening Your Immune System Against

... when we travel to parts of the world where sanitation standards are lower than ours, we routinely fall victim to pathogens that locals have no problems with. Our vulnerability to ‘Montezuma’s revenge’, ‘Delhi belly’ and many other travellers’ ills is largely due to our under-strength immune systems. ...
Live Attenuated Influenza Vaccine (FluMist®) Questions and
Live Attenuated Influenza Vaccine (FluMist®) Questions and

... LAIV (FluMist®) is made from attenuated viruses that are able to replicate efficiently only at temperatures present in the nasal mucosa. LAIV is manufactured using the 4 influenza virus strains recommended by the World Health Organization (WHO) for the northern hemisphere. Through manufacturing proc ...
Consulta: subjectFacets:"Vaccine" Registros recuperados: 76 Data
Consulta: subjectFacets:"Vaccine" Registros recuperados: 76 Data

... plasmid vectors and transformed into E. coli. Seventeen groups of specific-pathogen free (SPF), birds at four weeks of age were used to inoculate these two proteins (MGC1 and MGC2) mixed into an oil emulsion creating a novel MG vaccine. Six different protein concentrations (50, 100, 200, 400, 800, a ...
Pattern recognition receptors: sentinels in innate - e
Pattern recognition receptors: sentinels in innate - e

... generation of vaccine adjuvants is also discussed. Keywords : host defense • inflammasome • innate immunity • nucleotide-binding oligomerization domain-like receptor • pattern recognition receptor • retinoic acid-inducible gene-I-like receptor • Toll-like receptor • vaccine adjuvant ...
phoPlphoQ-Deleted Salmonella typhi (Ty800) Is a Safe and
phoPlphoQ-Deleted Salmonella typhi (Ty800) Is a Safe and

... SM10 A pir. The resultant suicide vector was mobilized via conjugal transfer to the chromosome of Ty2, using plasmid-encoded ampicillin resistance and the leucine, threonine, and thiamine auxotrophies of E. coli SM lOA pir for selection. Subsequently, selection against the vector-encoded sacB gene o ...
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Herd immunity



Herd immunity (also called herd effect, community immunity, population immunity, or social immunity) is a form of indirect protection from infectious disease that occurs when a large percentage of a population has become immune to an infection, thereby providing a measure of protection for individuals who are not immune. In a population in which a large number of individuals are immune, chains of infection are likely to be disrupted, which stops or slows the spread of disease. The greater the proportion of individuals in a community who are immune, the smaller the probability that those who are not immune will come into contact with an infectious individual.Individual immunity can be gained through recovering from a natural infection or through artificial means such as vaccination. Some individuals cannot become immune due to medical reasons and in this group herd immunity is an important method of protection. Once a certain threshold has been reached, herd immunity will gradually eliminate a disease from a population. This elimination, if achieved worldwide, may result in the permanent reduction in the number of infections to zero, called eradication. This method was used for the eradication of smallpox in 1977 and for the regional elimination of other diseases. Herd immunity does not apply to all diseases, just those that are contagious, meaning that they can be transmitted from one individual to another. Tetanus, for example, is infectious but not contagious, so herd immunity does not apply.The term herd immunity was first used in 1923. It was recognized as a naturally occurring phenomenon in the 1930s when it was observed that after a significant number of children had become immune to measles, the number of new infections temporarily decreased, including among susceptible children. Mass vaccination to induce herd immunity has since become common and proved successful in preventing the spread of many infectious diseases. Opposition to vaccination has posed a challenge to herd immunity, allowing preventable diseases to persist in or return to communities that have inadequate vaccination rates.
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