NAME OF LABORATORY: The Research Center for Digestive Tract
... Immune homeostatic responses in the intestinal mucosa. How does the intestinal epithelium respond to commensal flora (bacteria, fungi) and consequently activates the intestinal immune system. Identifying genetic, molecular, microbial, serologic, immune, nutritional and environmental factors associat ...
... Immune homeostatic responses in the intestinal mucosa. How does the intestinal epithelium respond to commensal flora (bacteria, fungi) and consequently activates the intestinal immune system. Identifying genetic, molecular, microbial, serologic, immune, nutritional and environmental factors associat ...
Gum Disease and Diabetes
... A study in the Journal of Periodontology found that poorly controlled type 2 diabetic patients are more likely to develop periodontal disease than well-controlled diabetics are. Research has emerged that suggests that the relationship between periodontal disease and diabetes goes both ways - periodo ...
... A study in the Journal of Periodontology found that poorly controlled type 2 diabetic patients are more likely to develop periodontal disease than well-controlled diabetics are. Research has emerged that suggests that the relationship between periodontal disease and diabetes goes both ways - periodo ...
Medical Shorts
... • FBC often have anaemia of chronic disease • X-ray Decreased joint space Soft tissue swelling Juxta-articular osteopenia (as pannus of inflammation thins it) Maybe: bony erosions, subluxation ...
... • FBC often have anaemia of chronic disease • X-ray Decreased joint space Soft tissue swelling Juxta-articular osteopenia (as pannus of inflammation thins it) Maybe: bony erosions, subluxation ...
Holistic view of root canal treatment
... 10.1016/j.joen.2012.12.028.12.Marton IJ et. al.,Differential in situ distribution of interleukin-8, monocyte chemoattractant protein-1 and Rantes in human chronic periapical granuloma. Oral Microbiol Immunol. 2000 Feb;15(1):63-5.13 Martinho FC et. al., Antigenic activity of bacterial endodontic cont ...
... 10.1016/j.joen.2012.12.028.12.Marton IJ et. al.,Differential in situ distribution of interleukin-8, monocyte chemoattractant protein-1 and Rantes in human chronic periapical granuloma. Oral Microbiol Immunol. 2000 Feb;15(1):63-5.13 Martinho FC et. al., Antigenic activity of bacterial endodontic cont ...
Chalazion A chalazion is a swelling in the eyelid
... Sometimes a chalazion can cause the entire eyelid to swell suddenly, but usually there is a particular tender point. When a chalazion is small and without symptoms, it may disappear on its own. If the chalazion is large, it may cause blurred vision. Chalazions are treated with any or a combination o ...
... Sometimes a chalazion can cause the entire eyelid to swell suddenly, but usually there is a particular tender point. When a chalazion is small and without symptoms, it may disappear on its own. If the chalazion is large, it may cause blurred vision. Chalazions are treated with any or a combination o ...
The Immune System and Infertility
... In the ejaculate, sperm antibodies can cause infertility by affecting sperm mobility or binding to the egg, although it is still unclear what level of antibodies is significant to warrant treatment. It is now known that immunosuppressive therapy (e.g. Prednisolone tablets) does not improve fertility ...
... In the ejaculate, sperm antibodies can cause infertility by affecting sperm mobility or binding to the egg, although it is still unclear what level of antibodies is significant to warrant treatment. It is now known that immunosuppressive therapy (e.g. Prednisolone tablets) does not improve fertility ...
Biology of
... accompanied by increased activation of the subgenual anterior cingulate cortex (sgACC) and decreased connectivity of the sgACC with the amygdala, prefrontal cortex, nucleus accumbens, and superior temporal sulcus in response to emotional stimuli [28]. A similar pattern of heightened sgACC activity h ...
... accompanied by increased activation of the subgenual anterior cingulate cortex (sgACC) and decreased connectivity of the sgACC with the amygdala, prefrontal cortex, nucleus accumbens, and superior temporal sulcus in response to emotional stimuli [28]. A similar pattern of heightened sgACC activity h ...
AUTOIMMUNE DISEASES Systemic VS Organ
... together to defend the body against infection, pollens, and toxins. Autoimmune disorders develop when the immune system cells err in their efforts to defend us from these potentially harmful agents. In autoimmune disease, the immune system is weak and ineffective. It fails to move along on its norma ...
... together to defend the body against infection, pollens, and toxins. Autoimmune disorders develop when the immune system cells err in their efforts to defend us from these potentially harmful agents. In autoimmune disease, the immune system is weak and ineffective. It fails to move along on its norma ...
幻灯片 1
... microbes or its products directly induce B cells to produce autoantibodies 2) MHC II expression abnormity: IFN-g、IL-1、IL-2、 MHCII 3) Assistant stimulator expression abnormity: 4) Th ratio or function unbalance: Th1/Th2 deviation 5) Fas、FasL expression abnormity: ...
... microbes or its products directly induce B cells to produce autoantibodies 2) MHC II expression abnormity: IFN-g、IL-1、IL-2、 MHCII 3) Assistant stimulator expression abnormity: 4) Th ratio or function unbalance: Th1/Th2 deviation 5) Fas、FasL expression abnormity: ...
Types of immune response
... A, Benign thymoma (medullary type). The neoplastic epithelial cells are arranged in a swirling pattern and have bland, oval to elongated nuclei with inconspicuous nucleoli. Only a few small, reactive lymphoid cells are interspersed. B, Malignant thymoma, type I. The neoplastic epithelial cells are p ...
... A, Benign thymoma (medullary type). The neoplastic epithelial cells are arranged in a swirling pattern and have bland, oval to elongated nuclei with inconspicuous nucleoli. Only a few small, reactive lymphoid cells are interspersed. B, Malignant thymoma, type I. The neoplastic epithelial cells are p ...
New Test in Celiac Disease Provides Powerful Tool for Diagnosis
... negative in all of the patients on a gluten-free diet who thought gluten was the cause of their digestive symptoms but did not have celiac disease. “The results from the blood test are highly encouraging and warrant further research and development. Additionally, this is an important step toward a t ...
... negative in all of the patients on a gluten-free diet who thought gluten was the cause of their digestive symptoms but did not have celiac disease. “The results from the blood test are highly encouraging and warrant further research and development. Additionally, this is an important step toward a t ...
Presentation
... consistent with its function (colon; upper airways) • Efforts to keep microbes out of some mucosal epithelial regions (small intestines and small airways) • Mechanisms include: actions of some surfactant proteins in lungs (bind to foreign polysaccharides); secretion of anti-microbial peptides by Pan ...
... consistent with its function (colon; upper airways) • Efforts to keep microbes out of some mucosal epithelial regions (small intestines and small airways) • Mechanisms include: actions of some surfactant proteins in lungs (bind to foreign polysaccharides); secretion of anti-microbial peptides by Pan ...
Issues in Biotechnology
... may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture’s disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medica ...
... may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture’s disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medica ...
1. Malar rash
... 3- nonspecific activation of T or B cells. 4- Autoantibodies to DNA, RNA:Circulating immune complexes (Ag &Ab complexes are frequently observed and these may deposit in the kidney, skin, brain, lung, and other tissues. It causes inflammation and tissue damage by a number of mechanisms, notably fixat ...
... 3- nonspecific activation of T or B cells. 4- Autoantibodies to DNA, RNA:Circulating immune complexes (Ag &Ab complexes are frequently observed and these may deposit in the kidney, skin, brain, lung, and other tissues. It causes inflammation and tissue damage by a number of mechanisms, notably fixat ...
Lectures 1 and 2
... with heparan sulphate proteoglycans. Non-phosphorylated tau isoforms with three microtubule-binding repeats form paired helical-like filaments under physiological conditions in vitro, when incubated with heparan sulphate. Heparin also prevents tau from binding to microtubules and promotes microtub ...
... with heparan sulphate proteoglycans. Non-phosphorylated tau isoforms with three microtubule-binding repeats form paired helical-like filaments under physiological conditions in vitro, when incubated with heparan sulphate. Heparin also prevents tau from binding to microtubules and promotes microtub ...
Lycera and Celgene Announce an Exclusive
... including Lycera's first-in-class RORgamma agonists for cancer immunotherapy, and clinicalstage candidate, LYC-30937, being studied for inflammatory bowel disease (IBD) NEW YORK and ANN ARBOR, Mich., June 9, 2015 /PRNewswire/ -- Lycera Corp., a privately held biopharmaceutical company developing bre ...
... including Lycera's first-in-class RORgamma agonists for cancer immunotherapy, and clinicalstage candidate, LYC-30937, being studied for inflammatory bowel disease (IBD) NEW YORK and ANN ARBOR, Mich., June 9, 2015 /PRNewswire/ -- Lycera Corp., a privately held biopharmaceutical company developing bre ...
GRANULOMATOUS DISEASES
... and connective tissue. Frequently, but not invariably, multinucleated giant cells 40 to 50 m in diameter are found in granulomas. They consists of a large mass of cytoplasm and many nuclei, and they derive from the fusion of 20 or more macrophages. In granulomas associated with certain infectious o ...
... and connective tissue. Frequently, but not invariably, multinucleated giant cells 40 to 50 m in diameter are found in granulomas. They consists of a large mass of cytoplasm and many nuclei, and they derive from the fusion of 20 or more macrophages. In granulomas associated with certain infectious o ...
Supplement to Supplement to Rheumatology News
... Activated T cells proliferate and secrete other cytokines that induce further proliferation. When cytokines, such as TNF, are locally produced in excess levels, enzymatic cleavage from the cell membrane releases them to enter the circulation, where they can cause remote effects, including stimulator ...
... Activated T cells proliferate and secrete other cytokines that induce further proliferation. When cytokines, such as TNF, are locally produced in excess levels, enzymatic cleavage from the cell membrane releases them to enter the circulation, where they can cause remote effects, including stimulator ...
SpectraCell Introduces Immunidex™
... 34 antioxidants, vitamins and minerals . It does not need to be ordered by a doctor unless the patient plans to submit it to insurance. It is a simple blood test and takes about two weeks to receive results. Over 3000 doctors currently use SpectraCell’s micronutrient test in their practice. More inf ...
... 34 antioxidants, vitamins and minerals . It does not need to be ordered by a doctor unless the patient plans to submit it to insurance. It is a simple blood test and takes about two weeks to receive results. Over 3000 doctors currently use SpectraCell’s micronutrient test in their practice. More inf ...
Meningococcal group C (Men C)
... Meningococcal disease is a life-threatening infection. It is a term used to describe two major illnesses – meningitis (inflammation of the membranes that surround the brain) and septicaemia (blood poisoning). These can occur on their own or more commonly both together. Most people will make a good r ...
... Meningococcal disease is a life-threatening infection. It is a term used to describe two major illnesses – meningitis (inflammation of the membranes that surround the brain) and septicaemia (blood poisoning). These can occur on their own or more commonly both together. Most people will make a good r ...
appendix_A002 - Differential Diagnosis for Physical Therapists
... • Postmenopausal vaginal bleeding (bleeding that occurs a year or more after the last period [significance depends on whether the woman is on hormone replacement therapy and which regimen is used]) • Bilateral symptoms (see Chapter 1) Numbness/tingling Burning Edema Clubbing or other nail bed change ...
... • Postmenopausal vaginal bleeding (bleeding that occurs a year or more after the last period [significance depends on whether the woman is on hormone replacement therapy and which regimen is used]) • Bilateral symptoms (see Chapter 1) Numbness/tingling Burning Edema Clubbing or other nail bed change ...
Document
... Indication: When sulphasalazine poorly tolerated No sulphonamide component As good as sulphasalazine & better tolerated MOA: Exact mechanism unknown Thought to work by inhibiting both COX & 5-lipo-oxygenase pathways of arachidonic acid metabolism → ↓inflammatory PG production Caution ...
... Indication: When sulphasalazine poorly tolerated No sulphonamide component As good as sulphasalazine & better tolerated MOA: Exact mechanism unknown Thought to work by inhibiting both COX & 5-lipo-oxygenase pathways of arachidonic acid metabolism → ↓inflammatory PG production Caution ...
Endocarditis: Some Basics - UCSF | Department of Medicine
... 1. Predisposing condition: intravenous drug use or predisposing cardiac condition 2. Fever ≥ 38.0° C 3. Vascular phenomena: arterial embolism, septic pulmonary emboli, mycotic aneurysm, intracranial hemorrhage, conjunctival hemorrhages, Janeway lesions 4. Immunologic phenomena: glomerulonephritis, O ...
... 1. Predisposing condition: intravenous drug use or predisposing cardiac condition 2. Fever ≥ 38.0° C 3. Vascular phenomena: arterial embolism, septic pulmonary emboli, mycotic aneurysm, intracranial hemorrhage, conjunctival hemorrhages, Janeway lesions 4. Immunologic phenomena: glomerulonephritis, O ...
Autoimmune Diseases
... -clinical presentation like AIDP (both motor & sensory involvement) -nerve conduction studies show axonal drop-out w/o significant slowing of conduction -low frequency in Europe and N. America -also assoc. w/ c. jejuni diarrheal disease -nerve conduction study shows focal slowing & conduction block ...
... -clinical presentation like AIDP (both motor & sensory involvement) -nerve conduction studies show axonal drop-out w/o significant slowing of conduction -low frequency in Europe and N. America -also assoc. w/ c. jejuni diarrheal disease -nerve conduction study shows focal slowing & conduction block ...
Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long lasting autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly the wrist and hands are involved with typically the same joints involved on both sides of the body. The disease may also affect other parts of the body. This may result in low red blood cells, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often symptoms come on gradually over weeks to months.While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is made mostly on the basis of a person's signs and symptoms. X-rays and laboratory testing may support a diagnosis or exclude other diseases with similar symptoms. Other diseases that may present similarly include systemic lupus erythematosus, psoriatic arthritis, and fibromyalgia among others.The goal of treatment is to improve pain, decrease inflammation, and improve a person's overall functioning. This may be helped by balancing rest and exercise, the use of splints and braces, or the use of assistive devices. Pain medications, steroids, and NSAIDs are frequently used to help with symptoms. A group of medications called disease-modifying antirheumatic drugs (DMARDs) may be used to try to slow the progression of disease. They include the medications hydroxychloroquine and methotrexate. Biological DMARDs may be used when disease does not respond to other treatments. However, they may have a greater rate of adverse effects. Surgery to repair, replace, or fusion joints may help in certain situations. Most alternative medicine treatments are not supported by evidence.RA affects between 0.5 and 1% of adults in the developed world with between 5 and 50 per 100,000 people newly developing the condition each year. Onset is most frequent during middle age and women are affected 2.5 times as frequently as men. In 2013 it resulted in 38,000 deaths up from 28,000 deaths in 1990. The first recognized description of RA was made in 1800 by Dr. Augustin Jacob Landré-Beauvais (1772–1840) of Paris. The term rheumatoid arthritis is based on the Greek for watery and inflamed joints.