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PSI+
PSI+

... skipping (21, 25, 26) as well as a scaffold for We found infectious prions capable of transmitting CWD in saliva (by the oral route) and in blood nuclear bodies through interactions with sur(by transfusion). The results help to explain the facile transmission of CWD among cervids and vival motor neu ...
The Centers for Disease Control and Prevention
The Centers for Disease Control and Prevention

... encephalopathy (BSE, or “mad cow disease”). Four cases in the United States, and two in Canada, have been identified.  None are believed to have been exposed to the infectious agent in North America based on epidemiological evidence including the decedents’ countries of origin, travel histories, an ...
Bovine Rhinotracheitis- Virus Diarrhea- Parainfluenza3
Bovine Rhinotracheitis- Virus Diarrhea- Parainfluenza3

... Laboratory diagnosis of BRSV has proven difficult, and only recently has it gained recognition as an important component of the bovine respiratory disease complex. As a causative agent, the virus is a pathogen of the lower respiratory tract with characteristic clinical signs of serous nasal discharg ...
Creutzfeldt-Jakob Disease
Creutzfeldt-Jakob Disease

... prion diseases are a unique group of neurological disorders that includes CJD, Gerstmann-SträusslerScheinker syndrome, and fatal familial insomnia. Human prion diseases present with progressive neurological symptoms and result in death, usually after a period of several months. There is no cure, alt ...
Synopsis - Web Adventures
Synopsis - Web Adventures

... to see a face now and then. My helminth cousins, the tapeworm, roundworm, and hookworm would so enjoy your company. You should give them a call. I promise you’ll never forget a visit from a helminth. Name: Prion Protein PrPsc: AKA “ The crazy cow” Acquired from: Brain of a cow with mad cow disease. ...
3-5 Protists
3-5 Protists

... water born infection in the United States. All regions of the United States have reported water contaminated with this protist. Since the protist can easily live for long periods of time outside a host’s body it is particularly difficult to control. Primary symptoms are watery diarrhea and stomach c ...
/tJ 8LOp YOU CAN' STOP BRUCELLOSIS
/tJ 8LOp YOU CAN' STOP BRUCELLOSIS

... It is one of the common INFECTIOUS DISEASES of humans in the United States. Two per cent of the SEVERE CASES CAUSE DEATH. Disability for long periods with frequent relapses after apparent recovery is common. ...
Infectious Disease - cancer
Infectious Disease - cancer

... = ----------------------------------------------------# people in group – index case(s) – Risk of H. Influenza infection in family members within 30 days of disease in an index case (compared to general ...
Agent-specific training form
Agent-specific training form

... AGENT-SPECIFIC TRAINING FORM Use this completed form to conduct and document agent-specific training for all research personnel who will work with the agent or animals infected with the agent, including husbandry personnel. Date Name of PI Name of agent, including strain, serotype, pathotype Has it ...
An acute bacterial disease, characterized by sudden onset of fever
An acute bacterial disease, characterized by sudden onset of fever

... intense headache, nausea and often vomiting, stiff neck and photophobia.  A petechial rash with pink macules or occasionally vesicles may be observed .  Case fatality rates formerly exceeded 50%.  Sequelae including mental retardation, hearing loss and paraplegia.  The gold standard for diagnosi ...
Respiratory Disease of Adult Cattle Respiratory Disease of
Respiratory Disease of Adult Cattle Respiratory Disease of

... of normal breath sounds from wheezes; no crackles were detected over lung pathology identified ultrasonographically in several studies. Ultrasonographic examination has been shown to accurately define the distribution and nature of lung pathology in those cows with advanced disease that have not res ...
The Royal College of Ophthalmologists In conjunction with the
The Royal College of Ophthalmologists In conjunction with the

... A key aspect of the guidance was to assess the relative tissue infectivity risk status for anterior and posterior segment tissues. Previous guidance from ACDP had stratified tissue infectivity risk in to high (posterior eye), medium (cornea and anterior eye) and low (other ocular tissues). There is ...
Lumpy skin disease Importance Lumpy skin disease is a poxviral
Lumpy skin disease Importance Lumpy skin disease is a poxviral

... reported in Asian water buffalo (Bubalus bubalis). Clinical cases or antibodies have been reported in other species such as oryx, but could have been caused by closely related poxviruses. Wild animals are not thought to play an important role in the spread or maintenance of LSDV. Geographic Distribu ...
now
now

... of normal breath sounds from wheezes; no crackles were detected over lung pathology identified ultrasonographically in several studies. Ultrasonographic examination has been shown to accurately define the distribution and nature of lung pathology in those cows with advanced disease that have not res ...
Inclusion Body Disease in Boas and Pythons
Inclusion Body Disease in Boas and Pythons

... animal, by particles in the air reaching healthy snakes kept in close proximity to sick ones, or by poor sanition practices leading to spread by the snakes’ keeper(s). In some cases, the snake mite Ophionyssus natricis has been found in populations where individuals were affected with IBD, but the m ...
infectious disease
infectious disease

...  List 3 common modes of disease transmission  Recognize situations in which disease transmission is likely to occur ...
blueprint to rid the world of neglected tropical diseases
blueprint to rid the world of neglected tropical diseases

... Neglected Tropical Diseases (NTDs) are a diverse group of communicable diseases that occur in tropical and subtropical conditions in 149 countries and affect more than 1 billion people. These diseases mainly affect populations living in poverty, without adequate sanitation and in close contact with ...
A1985TY22400001
A1985TY22400001

... Mareks disease herpesvirus, which causes lym- antigen over a period of several weeks. We phomas in chickens, is highly cell-associated. purposely included tissues from which virus Keratinized cells surrounding the feather shafts in could gain access to the environment, since the skin were found to b ...
Overview
Overview

... coronary band inflammation; and secondary bacterial infections such as pneumonia, mastitis, and metritis. Serum from young calves should not be submitted for antigen (virus) testing unless the sample was collected prior to feeding colostrum or the calf is >3 months of age. This is due to maternal an ...
Gene therapy - mvhs
Gene therapy - mvhs

... January 6, 2004 Available at http://www.sciencedaily.com/releases/2004/01/040106081302.htm Research by North Carolina State University scientists, in conjunction with scientists from the Netherlands and BioResource International, an NC State spin-off biotechnology company, has shown that, under prop ...
Hemorrhagic Disease in Tennessee Common Wildlife Diseases in
Hemorrhagic Disease in Tennessee Common Wildlife Diseases in

... (2007) throughout Tennessee (and other areas of the whitetails range). There have many calls asking about the significance and impact of the outbreak. Hopefully, the information below can help address some of the questions you may be receiving. Hemorrhagic disease is caused by either epizootic hemor ...
Infectious Bovine Rhinotracheitis
Infectious Bovine Rhinotracheitis

... darker as the infection progresses, and stands with its head and neck extended. Depression, higher body temperature (104 to 108 degrees F) and decreased appetite accompany the respiratory signs. As the infection progresses, the animal’s nostrils become encrusted, it loses weight rapidly and may have ...
Bovine Respiratory Disease
Bovine Respiratory Disease

... single dose caused more problems than if none were used. Great improvements have been made in recent years and several products are available, with more to come. Some of the killed products require two doses to stimulate protective immunity, but others are available for which one dose is sufficient. ...
do not write on this handout!!!
do not write on this handout!!!

... to limit contact between humans and mosquitos such as installing screens and bed nets and using insect repellant ...
Biosecurity in Dairy and Beef Cattle
Biosecurity in Dairy and Beef Cattle

... Infectious Bovine Rhinotracheitis (IBR) are just some examples of infectious diseases that can be introduced onto your cattle farm and severely affect its financial viability. Preventing them entering your farm and, once they've entered, minimising their spread can save significant amounts of money. ...
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Bovine spongiform encephalopathy



Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is a fatal neurodegenerative disease (encephalopathy) in cattle that causes a spongy degeneration in the brain and spinal cord. BSE has a long incubation period, about 2.5 to 8 years, usually affecting adult cattle at a peak age onset of four to five years, all breeds being equally susceptible. BSE is caused by a misfolded protein--a prion. In the United Kingdom, the country worst affected, more than 180,000 cattle have been infected and 4.4 million slaughtered during the eradication program.The disease may be most easily transmitted to human beings by eating food contaminated with the brain, spinal cord or digestive tract of infected carcasses. However, the infectious agent, although most highly concentrated in nervous tissue, can be found in virtually all tissues throughout the body, including blood. In humans, it is known as new variant Creutzfeldt–Jakob disease (vCJD or nvCJD), and by June 2014 it had killed 177 people in the United Kingdom, and 52 elsewhere. Between 460,000 and 482,000 BSE-infected animals had entered the human food chain before controls on high-risk offal were introduced in 1989.A British and Irish inquiry into BSE concluded the epizootic was caused by cattle, which are normally herbivores, being fed the remains of other cattle in the form of meat and bone meal (MBM), which caused the infectious agent to spread. The cause of BSE may be from the contamination of MBM from sheep with scrapie that were processed in the same slaughterhouse. The epidemic was probably accelerated by the recycling of infected bovine tissues prior to the recognition of BSE. The origin of the disease itself remains unknown. The infectious agent is distinctive for the high temperatures at which it remains viable, over 600 °C (about 1100 °F). This contributed to the spread of the disease in the United Kingdom, which had reduced the temperatures used during its rendering process. Another contributory factor was the feeding of infected protein supplements to very young calves.
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