294_2005_38_MOESM43_ESM - Springer Static Content Server
... have homologues of Rtn1, they tend to be larger but the variation in size is greater (35650 vs. 2939). There is evidence that Rtn2 interacts with Sho1 (Ito et al. 2001). Rtn2 is only found in the Saccharomyces sensu strictu group, which explains their extremely low coefficient of variation (0.2%). ...
... have homologues of Rtn1, they tend to be larger but the variation in size is greater (35650 vs. 2939). There is evidence that Rtn2 interacts with Sho1 (Ito et al. 2001). Rtn2 is only found in the Saccharomyces sensu strictu group, which explains their extremely low coefficient of variation (0.2%). ...
Structure-Function Relationship and Regulation of Two Bacillus
... family of proteins. DNA-Binding by HBsu DNA binding by HBsu is independent of cofactors or additional proteins. It has been shown to bind DNA unspecifically but with a preference for curved fragments (Köhler and Marahiel, 1998). Furthermore, HBsu enables b-recombinase-mediated recombination by stab ...
... family of proteins. DNA-Binding by HBsu DNA binding by HBsu is independent of cofactors or additional proteins. It has been shown to bind DNA unspecifically but with a preference for curved fragments (Köhler and Marahiel, 1998). Furthermore, HBsu enables b-recombinase-mediated recombination by stab ...
Whole body protein synthesis is an average of the synthesis rates
... muscle fibers are recruited increases in tension above 65% cause no further stimulation in muscle protein synthesis. Even though I am not aware if the specific fractions were measured in the Bowtell study it would stand to reason that in light of the previous both fractions would be up regulated. In ...
... muscle fibers are recruited increases in tension above 65% cause no further stimulation in muscle protein synthesis. Even though I am not aware if the specific fractions were measured in the Bowtell study it would stand to reason that in light of the previous both fractions would be up regulated. In ...
the RbDe web service - Oxford Academic
... the lack of better structural information, the term snake-like diagram has been coined, inspired by the layout of the sequence that spans the membrane several times. The automation of the rendering of snake-like diagrams, for proteins whose topology was similar to that of G proteincoupled receptors ...
... the lack of better structural information, the term snake-like diagram has been coined, inspired by the layout of the sequence that spans the membrane several times. The automation of the rendering of snake-like diagrams, for proteins whose topology was similar to that of G proteincoupled receptors ...
Abstract: Epitope-Enhanced Assay Sensitivity For Imaging
... proximity of a metallic nanoplasmonic surface. In order to specifically detect the absorbed molecules different assay formats can be used. In a direct assay an antibody is immobilized on the surface and the binding of the antigen can be measured. However, the success of this format is dependent on t ...
... proximity of a metallic nanoplasmonic surface. In order to specifically detect the absorbed molecules different assay formats can be used. In a direct assay an antibody is immobilized on the surface and the binding of the antigen can be measured. However, the success of this format is dependent on t ...
Xanthomonas campestris
... Plant proteins were also identified in the in vivo samples (Supporting Information Table 3). It was interesting to observe a lower diversity of the bacterial proteins identified in REU as well as a higher amount of plant proteins in this sample. Similar results were obtained by Villeth et al. [13] w ...
... Plant proteins were also identified in the in vivo samples (Supporting Information Table 3). It was interesting to observe a lower diversity of the bacterial proteins identified in REU as well as a higher amount of plant proteins in this sample. Similar results were obtained by Villeth et al. [13] w ...
Lipids affect the function of membrane proteins
... “These lipids are critical for mediating interactions in the membrane,” Robinson says. In collaboration with David Drew
of Stockholm University, Robinson’s team used mass spectrometry to study the role of lipids
in three analogous proteins called anti ...
... “These lipids are critical for mediating interactions in the membrane,” Robinson says. In collaboration with David Drew
PDF version
... genome and remains silent (lysogeny), as it awaits the right moment to trigger off growth. In so doing, the host becomes immune to infection by the same virus. But when is it the right moment to stop infection? And how is such a decision taken? Communication among bacteria is typically based on secr ...
... genome and remains silent (lysogeny), as it awaits the right moment to trigger off growth. In so doing, the host becomes immune to infection by the same virus. But when is it the right moment to stop infection? And how is such a decision taken? Communication among bacteria is typically based on secr ...
Document
... The challenge is to turn this raw data into biological knowledge A valuable tool for this challenge is an automated diagnostic pipe through which newly determined sequences can be streamlined ...
... The challenge is to turn this raw data into biological knowledge A valuable tool for this challenge is an automated diagnostic pipe through which newly determined sequences can be streamlined ...
Understanding the regulation of surfactant gene expression EDITORIAL W. Jacot, J. Bousquet
... without the N-terminal domain completely abolished the transcriptional activity whereas the mutant with the C-terminus deleted only partially reduced activity. Structurally, it has been suggested that the N-terminal domain has functional properties similar to the typical transactivation acidic domai ...
... without the N-terminal domain completely abolished the transcriptional activity whereas the mutant with the C-terminus deleted only partially reduced activity. Structurally, it has been suggested that the N-terminal domain has functional properties similar to the typical transactivation acidic domai ...
part 1
... • RMSD depends on protein size • Tricky to identify “equivalent residues” in the beginning • Usually means that a sequence alignment is done first • Aligned residues are considered “equivalent” • Means the method is only useful for sequences that can be aligned by sequence comparison • Several solut ...
... • RMSD depends on protein size • Tricky to identify “equivalent residues” in the beginning • Usually means that a sequence alignment is done first • Aligned residues are considered “equivalent” • Means the method is only useful for sequences that can be aligned by sequence comparison • Several solut ...
Self Menu Template (Men) - Lyn
... and chicken (animal protein) or bread (grain) and eggs (animal protein). Coconut Milk and animal proteins are a test. In winter we always have either a cooked vegetable or a soup with lunch to aid digestion. Dinner always has cooked vegetables and a raw veg salad as raw vegetables contain enzymes. C ...
... and chicken (animal protein) or bread (grain) and eggs (animal protein). Coconut Milk and animal proteins are a test. In winter we always have either a cooked vegetable or a soup with lunch to aid digestion. Dinner always has cooked vegetables and a raw veg salad as raw vegetables contain enzymes. C ...
2/17/12 Gene regulation
... • Most DNA-binding proteins interact with DNA in a sequence-specific manner • Specificity provided by interactions between amino acid side chains and chemical groups on the bases and sugar–phosphate backbone of DNA • Major groove of DNA is the main site of protein binding • Inverted repeats frequent ...
... • Most DNA-binding proteins interact with DNA in a sequence-specific manner • Specificity provided by interactions between amino acid side chains and chemical groups on the bases and sugar–phosphate backbone of DNA • Major groove of DNA is the main site of protein binding • Inverted repeats frequent ...
Intrinsically Disordered Proteins as Drug Targets
... The widespread implication of IDPs in disease, make them perfect candidates to drug design, but unluckily, it is not happening and there are only few drugs targeting IDPs. This fact is a great contradiction as there are bioinformatics studies showing that Post translational modifications (PTMs) pref ...
... The widespread implication of IDPs in disease, make them perfect candidates to drug design, but unluckily, it is not happening and there are only few drugs targeting IDPs. This fact is a great contradiction as there are bioinformatics studies showing that Post translational modifications (PTMs) pref ...
Preparation and characterization of antimicrobial proteins/ peptides
... human society. This impending crisis has spurred the search for new therapeutic agents with new modes of actions (Makovitzki et al., 2006) without developing resistance. The antimicrobial peptides (AMPs) show promise for becoming the next major group of natural antibiotics (Fleury et al., 1996) to c ...
... human society. This impending crisis has spurred the search for new therapeutic agents with new modes of actions (Makovitzki et al., 2006) without developing resistance. The antimicrobial peptides (AMPs) show promise for becoming the next major group of natural antibiotics (Fleury et al., 1996) to c ...
Sourirajan, Jayanthi: Protein Structure Prediction
... some fraction (helices and strands which can be assigned based on hydrogen bonding pattern) of the contacts is known and its 3D structure can be determined by distance geometry. But the contacts predicted by secondary structure are short range contacts. For application of distance geometry, contacts ...
... some fraction (helices and strands which can be assigned based on hydrogen bonding pattern) of the contacts is known and its 3D structure can be determined by distance geometry. But the contacts predicted by secondary structure are short range contacts. For application of distance geometry, contacts ...
In this section of the tutorial you will
... • Obtain a PRO ID for the protein objects of interest. For example, if you are modeling pathways you would like to be able to represent and refer to all the different forms of a given protein in order to describe the various reactions in the pathway. Each of these forms is a protein object in PRO an ...
... • Obtain a PRO ID for the protein objects of interest. For example, if you are modeling pathways you would like to be able to represent and refer to all the different forms of a given protein in order to describe the various reactions in the pathway. Each of these forms is a protein object in PRO an ...
Drosophila melanogaster
... structurally very different and are taxonomically unrelated, but their similar effects and potential common myosin binding site in the different muscles in which they are expressed might signal their functional homology. Previous work in the Vigoreaux lab developed a series of transgenic D. melanoga ...
... structurally very different and are taxonomically unrelated, but their similar effects and potential common myosin binding site in the different muscles in which they are expressed might signal their functional homology. Previous work in the Vigoreaux lab developed a series of transgenic D. melanoga ...
Explaining Gluten
... It’s not surprising that people have a difficult time understanding gluten, because it doesn’t exist in nature. Gluten is a water-insoluble protein that is formed when water is mixed with wheat flour. Proteins are very large molecules composed of amino acids. Two of the naturally occurring proteins ...
... It’s not surprising that people have a difficult time understanding gluten, because it doesn’t exist in nature. Gluten is a water-insoluble protein that is formed when water is mixed with wheat flour. Proteins are very large molecules composed of amino acids. Two of the naturally occurring proteins ...
Technologies for Proteomics
... Specifically, HILIC has been shown to enrich for glycosylation, N-acetylation, and phosphorylation. Peptides with N-acetyl modifications will elute as an early subfraction during a HILIC separation at relatively low water/organic mobile phase conditions. Phosphopeptides will elute within the middle ...
... Specifically, HILIC has been shown to enrich for glycosylation, N-acetylation, and phosphorylation. Peptides with N-acetyl modifications will elute as an early subfraction during a HILIC separation at relatively low water/organic mobile phase conditions. Phosphopeptides will elute within the middle ...
Cell Signaling
... Synthesis of the signaling molecule by the signaling cell Release of the signaling molecule by the signaling cell Transport of the signal to the target cell Binding of the signal by a specific receptor protein Æ conformational change Initiation of intracellular signal-transduction pathways by the ac ...
... Synthesis of the signaling molecule by the signaling cell Release of the signaling molecule by the signaling cell Transport of the signal to the target cell Binding of the signal by a specific receptor protein Æ conformational change Initiation of intracellular signal-transduction pathways by the ac ...
Spirulina - Sun Gates Center
... A species of edible micro-algae, Spirulina is a complete protein known for its essential and non-essential amino acids…62% easily digested plant protein! Spirulina is blue - green algae high in chlorophyll, iron, carotenoids, anti-oxidants and other micronutrients. As is the case with all whole food ...
... A species of edible micro-algae, Spirulina is a complete protein known for its essential and non-essential amino acids…62% easily digested plant protein! Spirulina is blue - green algae high in chlorophyll, iron, carotenoids, anti-oxidants and other micronutrients. As is the case with all whole food ...
EXPLORE ALL BINDING SITE SIMILARITIES INCLUDING
... sites into a relational database, (3) providing advanced data MEDP-SiteClassifier is a powerful biostructural data repository mining interface to analyze clusters and interfamily links in term of for molecular biologists and medicinal chemists to mine any local conserved SCF (Structural Chemical Fea ...
... sites into a relational database, (3) providing advanced data MEDP-SiteClassifier is a powerful biostructural data repository mining interface to analyze clusters and interfamily links in term of for molecular biologists and medicinal chemists to mine any local conserved SCF (Structural Chemical Fea ...
Peptide inhibitors of the essential cell division protein FtsA
... (van den Ent et al., 2001) presumably constitutes a key bacterial component because of its essential protein–protein interaction with FtsZ and its ATPase enzymatic activity (Errington et al., 2003) that can be exploited to screen and analyse inhibitory molecules. The FtsZ protein is at the top of hi ...
... (van den Ent et al., 2001) presumably constitutes a key bacterial component because of its essential protein–protein interaction with FtsZ and its ATPase enzymatic activity (Errington et al., 2003) that can be exploited to screen and analyse inhibitory molecules. The FtsZ protein is at the top of hi ...
Protein mass spectrometry
Protein mass spectrometry refers to the application of mass spectrometry to the study of proteins. Mass spectrometry is an important emerging method for the characterization of proteins. The two primary methods for ionization of whole proteins are electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI). In keeping with the performance and mass range of available mass spectrometers, two approaches are used for characterizing proteins. In the first, intact proteins are ionized by either of the two techniques described above, and then introduced to a mass analyzer. This approach is referred to as ""top-down"" strategy of protein analysis. In the second, proteins are enzymatically digested into smaller peptides using a protease such as trypsin. Subsequently these peptides are introduced into the mass spectrometer and identified by peptide mass fingerprinting or tandem mass spectrometry. Hence, this latter approach (also called ""bottom-up"" proteomics) uses identification at the peptide level to infer the existence of proteins.Whole protein mass analysis is primarily conducted using either time-of-flight (TOF) MS, or Fourier transform ion cyclotron resonance (FT-ICR). These two types of instrument are preferable here because of their wide mass range, and in the case of FT-ICR, its high mass accuracy. Mass analysis of proteolytic peptides is a much more popular method of protein characterization, as cheaper instrument designs can be used for characterization. Additionally, sample preparation is easier once whole proteins have been digested into smaller peptide fragments. The most widely used instrument for peptide mass analysis are the MALDI time-of-flight instruments as they permit the acquisition of peptide mass fingerprints (PMFs) at high pace (1 PMF can be analyzed in approx. 10 sec). Multiple stage quadrupole-time-of-flight and the quadrupole ion trap also find use in this application.