December 2008 - Maryland Poison Center
... caused a delay in antidotal treatment that could have been detrimental for the patient. This is not the first time that this error has occurred. Similar cases have been reported to other poison centers. The most likely reason for this medication error is that fomepizole sounds like omeprazole, anoth ...
... caused a delay in antidotal treatment that could have been detrimental for the patient. This is not the first time that this error has occurred. Similar cases have been reported to other poison centers. The most likely reason for this medication error is that fomepizole sounds like omeprazole, anoth ...
file (Poison Prevention Outreach Mt. Lebanon High School)
... Less life threatening, typically requiring a massive overdose to be fatal ...
... Less life threatening, typically requiring a massive overdose to be fatal ...
Heroin withdrawal precipitated by naltrexone
... Patients withdrawing become agitated and distressed, and may become delirious and confused. This is usually short-lived. Patients can usually be re-oriented. If they require sedation, rapidly acting benzodiazepines (e.g. diazepam 5 mg qid or midazolam 5-10 mg IM) are the drugs of choice. Significant ...
... Patients withdrawing become agitated and distressed, and may become delirious and confused. This is usually short-lived. Patients can usually be re-oriented. If they require sedation, rapidly acting benzodiazepines (e.g. diazepam 5 mg qid or midazolam 5-10 mg IM) are the drugs of choice. Significant ...
Lecture 1-approach to Toxicology
... Evaluate history and a thorough physical exam Look at vitals, pupils, neuro, skin, bowel sounds. . . Gives you hints regarding the general class of toxins Guides your supportive care ...
... Evaluate history and a thorough physical exam Look at vitals, pupils, neuro, skin, bowel sounds. . . Gives you hints regarding the general class of toxins Guides your supportive care ...
ACUTE POISONING
... • NAPQI toxic causes hepatocellular necrosis – irreversible binding • NAPQI detoxified by conjugation with glutathione ...
... • NAPQI toxic causes hepatocellular necrosis – irreversible binding • NAPQI detoxified by conjugation with glutathione ...
Medication Alternatives for the Elderly
... 1. Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly: an update. Arch Intern Med. 1997; 157: 1531-6 2. HEDIS® 2007 The Guide was prepared by Highmark Inc. and Quality Insights of Pennsylvania, the Medicare Quality Improvement Organization for Pennsyl ...
... 1. Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly: an update. Arch Intern Med. 1997; 157: 1531-6 2. HEDIS® 2007 The Guide was prepared by Highmark Inc. and Quality Insights of Pennsylvania, the Medicare Quality Improvement Organization for Pennsyl ...
Opioids The term opium comes from the Greek opos meaning juice
... to the juice of the opium poppy (Papaver somniferum). Opiate is the active substance that is obtained from the opium poppy (e.g. morphine). This natural product can be chemically changed creating semisynthetic derivatives. There are also fully synthetic substances and peptides gained from other anim ...
... to the juice of the opium poppy (Papaver somniferum). Opiate is the active substance that is obtained from the opium poppy (e.g. morphine). This natural product can be chemically changed creating semisynthetic derivatives. There are also fully synthetic substances and peptides gained from other anim ...
COGNITIVE MODEL OF EMOTIONAL DISTRESS
... factors for suicide at initiation of treatment, during any dose adjustment, and until improvement occurs Concomitant medicines that may increase the risk of toxicity associated with dosulepin should be avoided There is no immediate need to change treatment for established patients Patients should be ...
... factors for suicide at initiation of treatment, during any dose adjustment, and until improvement occurs Concomitant medicines that may increase the risk of toxicity associated with dosulepin should be avoided There is no immediate need to change treatment for established patients Patients should be ...
OPIOIDS
... • Stoppage (or reduction] in opioid use that has been heavy and prolonged (several weeks +) • OR administration of opioid antagonist after period of use • Symptoms include: (need at least 3 for DSM criteria) ...
... • Stoppage (or reduction] in opioid use that has been heavy and prolonged (several weeks +) • OR administration of opioid antagonist after period of use • Symptoms include: (need at least 3 for DSM criteria) ...
General Anaesthetics
... The effects of these drugs depend on previous exposure to opioids: In individuals who have not received opioids (naive patients), mixed agonist– antagonists show agonist activity and are used to relieve pain. In the patient with opioid dependence, the agonist–antagonist drugs may show primaril ...
... The effects of these drugs depend on previous exposure to opioids: In individuals who have not received opioids (naive patients), mixed agonist– antagonists show agonist activity and are used to relieve pain. In the patient with opioid dependence, the agonist–antagonist drugs may show primaril ...
HYDROcodone/acetaminophen HYDROcodone/ibuprofen
... use or high doses of acetaminophen. Renal damage may occur with prolonged use of acetaminophen or ibuprofen. Doses of nonopioid agents should not exceed the maximum recommended daily dose. Do not stop taking without discussing with health care professional; my cause withdrawal symptoms if discontinu ...
... use or high doses of acetaminophen. Renal damage may occur with prolonged use of acetaminophen or ibuprofen. Doses of nonopioid agents should not exceed the maximum recommended daily dose. Do not stop taking without discussing with health care professional; my cause withdrawal symptoms if discontinu ...
Narcan Overview - Telco House Bed & Breakfast
... push; repeat as indicated (per protocol) SC; repeat as indicated (per protocol) ...
... push; repeat as indicated (per protocol) SC; repeat as indicated (per protocol) ...
Pharmacology - Shelbye's CSON Notes Blog
... – Lower surface tension of stool and softens by facilitating penetration of water into the feces – Act on intestinal wall to inhibit fluid absorption and stimulate secretion of water and electrolytes into the intestinal lumen. – Brings water into the stool and makes it softer ...
... – Lower surface tension of stool and softens by facilitating penetration of water into the feces – Act on intestinal wall to inhibit fluid absorption and stimulate secretion of water and electrolytes into the intestinal lumen. – Brings water into the stool and makes it softer ...
ALPRAZolam (al-pray-zoe-lam) - DavisPlus
... usually disappear as therapy progresses. Dose should be reduced if these symptoms persist. Geri: Assess CNS effects and risk of falls. Institute falls prevention strategies. Prolonged high-dose therapy may lead to psychological or physical dependence. Risk is greater in patients taking ⬎4 mg/day. Re ...
... usually disappear as therapy progresses. Dose should be reduced if these symptoms persist. Geri: Assess CNS effects and risk of falls. Institute falls prevention strategies. Prolonged high-dose therapy may lead to psychological or physical dependence. Risk is greater in patients taking ⬎4 mg/day. Re ...
Table of Antidotes (Word Document, 20kB)
... formation of methemoglobin, which combines with cyanide to form nontoxic cyanmethemoglobin. ...
... formation of methemoglobin, which combines with cyanide to form nontoxic cyanmethemoglobin. ...
Document
... dosages of the various currently available formulations, which represent the maximum safe dose of a 2 % local anesthetic agent with epinephrine or levonordefrin? 11. Recognize the signs and symptoms associated with adverse reactions to local anesthetics, such as allergic reactions, vasopressor respo ...
... dosages of the various currently available formulations, which represent the maximum safe dose of a 2 % local anesthetic agent with epinephrine or levonordefrin? 11. Recognize the signs and symptoms associated with adverse reactions to local anesthetics, such as allergic reactions, vasopressor respo ...
Opioids in Persistent Pain
... Why Prescribe? Adverse effects Practical Prescribing Opioids and problem drug use ...
... Why Prescribe? Adverse effects Practical Prescribing Opioids and problem drug use ...
HEROIN WITHDRAWAL PRECIPITATED BY NALTREXONE DACAS
... This information should be read in conjunction with the product information literature from the distributor, Orphan Australia (phone (03) 9769 5744). These notes have been modified from a longer document written by Dr Malcolm Young as part of the National Evaluation of Pharmacotherapies for Opioid D ...
... This information should be read in conjunction with the product information literature from the distributor, Orphan Australia (phone (03) 9769 5744). These notes have been modified from a longer document written by Dr Malcolm Young as part of the National Evaluation of Pharmacotherapies for Opioid D ...
codeine (koe-deen) - DavisPlus
... when changing from one opioid to another. Prolonged use may lead to physical and psychological dependence and tolerance. This should not prevent patient from receiving adequate analgesia. Most patients who receive codeine for pain do not develop psychological dependence. If progressively higher dose ...
... when changing from one opioid to another. Prolonged use may lead to physical and psychological dependence and tolerance. This should not prevent patient from receiving adequate analgesia. Most patients who receive codeine for pain do not develop psychological dependence. If progressively higher dose ...
Alcohol and Other Drug Emergencies
... • All AOD presentations will benefit from brief interventions to try and engage with withdrawal management in community ...
... • All AOD presentations will benefit from brief interventions to try and engage with withdrawal management in community ...
The Slippery Slope of Relieving Pain: Be Wary of Opioid Drugs
... This is especially true of methadone. Methadone’s peak respiratory depressant effects typically occur later, and last longer, than its peak painkilling effects. Overdoses often occur when someone takes methadone for the first time or the dose is increased. What is worse, doctors prescribing various ...
... This is especially true of methadone. Methadone’s peak respiratory depressant effects typically occur later, and last longer, than its peak painkilling effects. Overdoses often occur when someone takes methadone for the first time or the dose is increased. What is worse, doctors prescribing various ...
Poisoning and OD PPT
... Splinting of injected body part Cold packs (+) [May worsen local injury by concentrating poison] ...
... Splinting of injected body part Cold packs (+) [May worsen local injury by concentrating poison] ...
Dextropropoxyphene
Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company. It is an optical isomer of levopropoxyphene. It is intended to treat mild pain and also has antitussive (cough suppressant) and local anaesthetic effects. The drug has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias. Its onset of analgesia (pain relief) is said to be 20–30 minutes and peak effects are seen about 1.5–2 hours after oral administration.Dextropropoxyphene is sometimes combined with acetaminophen or aspirin. Trade names include Darvocet-N and Di-Gesic, Darvon with APAP (for dextropropoxyphene and paracetamol) and Darvon with ASA (for dextropropoxyphene and aspirin). The British approved name (i.e. the generic name of the active ingredient) of the paracetamol/dextropropoxyphene preparation is ""co-proxamol"" (sold under a variety of brand names); however, it has been withdrawn since 2007, and is no longer available to new patients, with exceptions. The paracetamol combination(s) are known as Capadex or Di-Gesic in Australia, Lentogesic in South Africa, and Di-Antalvic in France (unlike co-proxamol, which is an approved name, these are all brand names).Dextropropoxyphene is known under several synonyms, including: Alpha-d-4-dimethylamino-3-methyl-1,2-diphenyl-2-butanol propionate [(2S,3S)-4-(Dimethylamino)-3- methyl-1,2-diphenylbutan-2-yl] propanoate (+)-1,2-Diphenyl-2-propionoxy- 3-methyl-4-di-methylaminobutane Desoxypropiophen↑ 1.0 1.1 1.2 1.3 1.4 ↑ ↑ ↑ ↑ ↑ ↑ ↑