Management of Ocular Pain and Inflammation
... •Block central pain receptors, reduce perception of pain-They feel pain, but don’t care •Allergic to one opiate, allergic to all opiates •Know your schedules •Schedule II, high abuse, V= low abuse •Know your side-effects COMBINATION OPIATE ANALGESICS •Propoxyphene + •Propoxyphene + •Codeine + •Hydro ...
... •Block central pain receptors, reduce perception of pain-They feel pain, but don’t care •Allergic to one opiate, allergic to all opiates •Know your schedules •Schedule II, high abuse, V= low abuse •Know your side-effects COMBINATION OPIATE ANALGESICS •Propoxyphene + •Propoxyphene + •Codeine + •Hydro ...
Pharmacology—Clinical Uses of Sedatives
... 2) Injectable forms available for anesthesia, status epilepticus. More likely to cause respiratory depression 3) Liver metabolism – many converted to active metabolites during phase 1 reactions. Metabolites may have longer half life. Duration of action is related to the metabolites 4) At lower doses ...
... 2) Injectable forms available for anesthesia, status epilepticus. More likely to cause respiratory depression 3) Liver metabolism – many converted to active metabolites during phase 1 reactions. Metabolites may have longer half life. Duration of action is related to the metabolites 4) At lower doses ...
Clincial Pharmacology of Analgesic Medications
... Single dose, onset of 10-20 min., t1/2 of 24 h + (variable) and analgesia duration of 4-8 hours Chronic - Accumulates with repeated dosing; incomplete cross tolerance with opiates, may require dosage reduction or increased dosing intervals. Need a week to see full effect of ...
... Single dose, onset of 10-20 min., t1/2 of 24 h + (variable) and analgesia duration of 4-8 hours Chronic - Accumulates with repeated dosing; incomplete cross tolerance with opiates, may require dosage reduction or increased dosing intervals. Need a week to see full effect of ...
Analgesic Drugs
... • Weak, long-acting μ-receptor agonists, such as methadone, may be used to relieve withdrawal symptoms. • Certain opioid analgesics, such as codeine and pentazocine, are much less likely to cause physical or psychological dependence. ...
... • Weak, long-acting μ-receptor agonists, such as methadone, may be used to relieve withdrawal symptoms. • Certain opioid analgesics, such as codeine and pentazocine, are much less likely to cause physical or psychological dependence. ...
Analgesics
... Due to difficulties in procuring heroin combined with easy/cheap access to OTC products containing codeine in Russia, its use has been on the rise. High is similar to heroin but shorter. While heroin lasts 4-8 hours, effects of krokodil lasts 1-1.5 hours. Tramadol (Ultram-1994 in US) ...
... Due to difficulties in procuring heroin combined with easy/cheap access to OTC products containing codeine in Russia, its use has been on the rise. High is similar to heroin but shorter. While heroin lasts 4-8 hours, effects of krokodil lasts 1-1.5 hours. Tramadol (Ultram-1994 in US) ...
Appropriate Drug Prescribing in Older Adults
... Propoxyphene (Darvocet) – ineffective analgeisic with class adverse effects Potentially problematic due to varied CYP450 metabolism Codeine Tramadol (Ultram) Known Class Adverse Effects Constipation Somnolence, Confusion, Falls Pruritis Nausea Dependence and Tolerance ...
... Propoxyphene (Darvocet) – ineffective analgeisic with class adverse effects Potentially problematic due to varied CYP450 metabolism Codeine Tramadol (Ultram) Known Class Adverse Effects Constipation Somnolence, Confusion, Falls Pruritis Nausea Dependence and Tolerance ...
Withdrawal
... • Stabilization on Methadone: -Initial dose: A:10-20mg→ if withdrawal persist → Repeat the dose( 2 hours later ) [ no more than 40mg during first day]. B: Calculation of equivalent withdrawal suppressing dose of methadone? (Methadone is 3time potent than morphine). C: Add 10mg/2-3day or week( differ ...
... • Stabilization on Methadone: -Initial dose: A:10-20mg→ if withdrawal persist → Repeat the dose( 2 hours later ) [ no more than 40mg during first day]. B: Calculation of equivalent withdrawal suppressing dose of methadone? (Methadone is 3time potent than morphine). C: Add 10mg/2-3day or week( differ ...
Paracetamol toxicity
... Multiple overdoses — In contrast to chronic alcoholics with an isolated ingestion, chronic alcoholics appear to be at increased risk for hepatotoxicity following ingestion of multiple supratherapeutic doses of PARA. Chronic liver disease who do not regularly ingest alcohol do NOT appear to be at ...
... Multiple overdoses — In contrast to chronic alcoholics with an isolated ingestion, chronic alcoholics appear to be at increased risk for hepatotoxicity following ingestion of multiple supratherapeutic doses of PARA. Chronic liver disease who do not regularly ingest alcohol do NOT appear to be at ...
Product Manual
... Newborn infants are particularly sensitive to central nervous system depression caused by benzodiazepines, which can result in respiratory depression, low muscle tone and blood pressure, transient hypothermia, sucking weakness ("flabby child" syndrome). Fenazepam excreted in breast milk, therefore i ...
... Newborn infants are particularly sensitive to central nervous system depression caused by benzodiazepines, which can result in respiratory depression, low muscle tone and blood pressure, transient hypothermia, sucking weakness ("flabby child" syndrome). Fenazepam excreted in breast milk, therefore i ...
Pain (Medications and their Prescription) 311 MDS Dr. Hesham Kh
... Prescribing during pregnancy: Medications can have harmful effects on the foetus at any time during pregnancy. Drugs should be prescribed in pregnancy only if the expected benefit to the mother is recognized as being greater than the risk to the foetus, and all medications should be avoided if possi ...
... Prescribing during pregnancy: Medications can have harmful effects on the foetus at any time during pregnancy. Drugs should be prescribed in pregnancy only if the expected benefit to the mother is recognized as being greater than the risk to the foetus, and all medications should be avoided if possi ...
VETS 238 Surgical Nursing and Anesthesia
... medetomidine(10ug/kg) + butorphanol(0.2mg/kg) mixed and given IM ...
... medetomidine(10ug/kg) + butorphanol(0.2mg/kg) mixed and given IM ...
![Opioid Presentation (updated) [Compatibility Mode]](http://s1.studyres.com/store/data/004292630_1-ae2220d6a1ea3f0b38c40b7874481e9e-300x300.png)
Opioid Presentation (updated) [Compatibility Mode]
... sleep like state, it is no longer a medically useful term because it has been hi jacked into legal circles and is now often used to include many other drugs used illegally such as cannabanoids, amphetamines, etc that have nothing to do with opium. ...
... sleep like state, it is no longer a medically useful term because it has been hi jacked into legal circles and is now often used to include many other drugs used illegally such as cannabanoids, amphetamines, etc that have nothing to do with opium. ...
Pain Management - Stueck Pharmacy Ltd.
... Peak respiratory depressant effects occur later, and persist longer than its peak analgesic effects Risk of QT prolongation Many drug interactions ...
... Peak respiratory depressant effects occur later, and persist longer than its peak analgesic effects Risk of QT prolongation Many drug interactions ...
acetaminophen (paracetamol)
... Soluble in water. Major use Acetaminophen is analgesic and anti-pyretic drug, with some anti-inflammatory activity. Human toxicity Initial adverse effects of poisoning may be non-specific (nausea or vomiting) or absent. Clinical signs include e.g. hepatic necrosis, metabolic acidosis; renal tubular ...
... Soluble in water. Major use Acetaminophen is analgesic and anti-pyretic drug, with some anti-inflammatory activity. Human toxicity Initial adverse effects of poisoning may be non-specific (nausea or vomiting) or absent. Clinical signs include e.g. hepatic necrosis, metabolic acidosis; renal tubular ...
Slide 1
... (agonist), M3G High addictive potential (rush (neurotoxicity), may and stimulant effect) accumulate in renal failure More CNS toxicity (i.e. seizures, delirium due to norpethidine metabolite Should not be used any more ...
... (agonist), M3G High addictive potential (rush (neurotoxicity), may and stimulant effect) accumulate in renal failure More CNS toxicity (i.e. seizures, delirium due to norpethidine metabolite Should not be used any more ...
Low Back Pain Ch Summary HP 1013
... Acetaminophen may ↑ anticoagulant effect of warfarin (ie. > 1.3g/day acetaminophen for > 1 week). Acetaminophen + alcohol, may ↑ risk of hepatotoxicity (>3 drinks/day). NSAIDs may ↑ risk of bleeding with anticoagulants (eg. warfarin) or antiplatelet drugs (eg. clopidogrel), may ↑ risk of GI bleed wh ...
... Acetaminophen may ↑ anticoagulant effect of warfarin (ie. > 1.3g/day acetaminophen for > 1 week). Acetaminophen + alcohol, may ↑ risk of hepatotoxicity (>3 drinks/day). NSAIDs may ↑ risk of bleeding with anticoagulants (eg. warfarin) or antiplatelet drugs (eg. clopidogrel), may ↑ risk of GI bleed wh ...
Prescription Drug Abuse Part I Introduction By James
... physician's close supervision. Typically, they should not be combined with any other medication or substance that causes CNS depression, including prescription pain medicines, some OTC cold and allergy medications, and alcohol. Using CNS depressants with these other substances - particularly alcohol ...
... physician's close supervision. Typically, they should not be combined with any other medication or substance that causes CNS depression, including prescription pain medicines, some OTC cold and allergy medications, and alcohol. Using CNS depressants with these other substances - particularly alcohol ...
Brevital - DavisPlus
... somnolence and respiratory and circulatory depression. If the patient requires a second anesthetic in the same day, reduction in the dose of methohexital may be required. Methohexital may be given in doses sufficient to produce deep surgical anesthesia, but such doses may cause dangerous respiratory ...
... somnolence and respiratory and circulatory depression. If the patient requires a second anesthetic in the same day, reduction in the dose of methohexital may be required. Methohexital may be given in doses sufficient to produce deep surgical anesthesia, but such doses may cause dangerous respiratory ...
Why Opioids Are Addictive : Bio Energy Patch
... though it may be having harmful effects on their life and their health. They have strong urges to take the drug—called cravings—and they no longer feel satisfied by natural rewards (like chocolate, TV, or a walk on the beach). If you've ever seen The Wizard of Oz, then you've seen the poppy plant—th ...
... though it may be having harmful effects on their life and their health. They have strong urges to take the drug—called cravings—and they no longer feel satisfied by natural rewards (like chocolate, TV, or a walk on the beach). If you've ever seen The Wizard of Oz, then you've seen the poppy plant—th ...
Safe Opioid Prescribing
... In anything other than acute emergencies, the healthcare practitioner concerned or their clinical supervisor should: Confirm any recent opioid dose, formulation, frequency of administration and any other analgesic medicines prescribed for the patient This can be done through discussion with the pati ...
... In anything other than acute emergencies, the healthcare practitioner concerned or their clinical supervisor should: Confirm any recent opioid dose, formulation, frequency of administration and any other analgesic medicines prescribed for the patient This can be done through discussion with the pati ...
Drugs of Abuse - California Society of Addiction Medicine
... inflammatory pain in cancer patients) Asthma Glaucoma Appetite stimulant ...
... inflammatory pain in cancer patients) Asthma Glaucoma Appetite stimulant ...
Morphine vs Hydromorphone vs Oxycodone vs the Patch
... Fentanyl: Transdermal (Duragesic) and parenteral formulations are available. · high lipid solubility · 50100 time more potent than morphine · Transdermal patch convenient in patients with stable pain control. Caution advised in uncontrolled pain syndromes (not suitable for rapid titration) · Possi ...
... Fentanyl: Transdermal (Duragesic) and parenteral formulations are available. · high lipid solubility · 50100 time more potent than morphine · Transdermal patch convenient in patients with stable pain control. Caution advised in uncontrolled pain syndromes (not suitable for rapid titration) · Possi ...
meperidine - DavisPlus
... the patient reports satisfactory pain relief. A repeat dose can be safely administered at the time of the peak if previous dose is ineffective and side effects are minimal. An equianalgesic chart (see Appendix B) should be used when changing routes or when changing from one opioid to another. Assess ...
... the patient reports satisfactory pain relief. A repeat dose can be safely administered at the time of the peak if previous dose is ineffective and side effects are minimal. An equianalgesic chart (see Appendix B) should be used when changing routes or when changing from one opioid to another. Assess ...
intravenous paracetamol
... Treatment of IV paracetamol overdose Paracetamol is metabolised in the liver by glucuronidation and sulphation; a small proportion is metabolised by oxidation to toxic metabolites such as N-acetyl-p-benzoquinone-imine. Benzoquinoneimine is combined with glutathione and is excreted safely in the urin ...
... Treatment of IV paracetamol overdose Paracetamol is metabolised in the liver by glucuronidation and sulphation; a small proportion is metabolised by oxidation to toxic metabolites such as N-acetyl-p-benzoquinone-imine. Benzoquinoneimine is combined with glutathione and is excreted safely in the urin ...
Dextropropoxyphene
Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company. It is an optical isomer of levopropoxyphene. It is intended to treat mild pain and also has antitussive (cough suppressant) and local anaesthetic effects. The drug has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias. Its onset of analgesia (pain relief) is said to be 20–30 minutes and peak effects are seen about 1.5–2 hours after oral administration.Dextropropoxyphene is sometimes combined with acetaminophen or aspirin. Trade names include Darvocet-N and Di-Gesic, Darvon with APAP (for dextropropoxyphene and paracetamol) and Darvon with ASA (for dextropropoxyphene and aspirin). The British approved name (i.e. the generic name of the active ingredient) of the paracetamol/dextropropoxyphene preparation is ""co-proxamol"" (sold under a variety of brand names); however, it has been withdrawn since 2007, and is no longer available to new patients, with exceptions. The paracetamol combination(s) are known as Capadex or Di-Gesic in Australia, Lentogesic in South Africa, and Di-Antalvic in France (unlike co-proxamol, which is an approved name, these are all brand names).Dextropropoxyphene is known under several synonyms, including: Alpha-d-4-dimethylamino-3-methyl-1,2-diphenyl-2-butanol propionate [(2S,3S)-4-(Dimethylamino)-3- methyl-1,2-diphenylbutan-2-yl] propanoate (+)-1,2-Diphenyl-2-propionoxy- 3-methyl-4-di-methylaminobutane Desoxypropiophen↑ 1.0 1.1 1.2 1.3 1.4 ↑ ↑ ↑ ↑ ↑ ↑ ↑