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engaging aboriginal and torres strait islander communities in
engaging aboriginal and torres strait islander communities in

... Northern Territory. This was a standardised rate of 27 new cases per 100,000 men (11). The age-standardised incidence of prostate cancer in Australian men has increased over time, from 79 new cases per 100,000 men in 1982 to 194 per 100,000 in 2009. This increase is expected to continue, reaching 25 ...
pectin induces apoptosis in human prostate
pectin induces apoptosis in human prostate

... Figure 3.5: Use of OGA-PAGE to probe the effects of chemical and enzymatic treatment of FPP on its apoptosis-inducing activity..................................................................................61 ...
Molecular genetics of prostate cancer: new prospects for old challenges
Molecular genetics of prostate cancer: new prospects for old challenges

Real Hope
Real Hope

Cancer Then Now Report Final online
Cancer Then Now Report Final online

RADICALS Radiotherapy and Androgen Deprivation In Combination
RADICALS Radiotherapy and Androgen Deprivation In Combination

... University College London (UCL), and provides information about procedures for entering patients into it. The protocol should not be used as an aide-memoire or guide for the treatment of other patients. Every care has been taken in drafting this protocol, but corrections or amendments may be necessa ...
HOW YOUR LIFESTYLE CAN CAUSE OR PREVENT CANCER
HOW YOUR LIFESTYLE CAN CAUSE OR PREVENT CANCER

... moderate intensity or 75 minutes of vigorous intensity activity each week, spread throughout the week Children and adolescents: Get 60 minutes/day of moderate to vigorous physical activity each day, with vigorous activity at least 3 days/week ...
Ovarian cancer screening—Current status, future directions
Ovarian cancer screening—Current status, future directions

... second best performing marker with a sensitivity of 73% [24]. HE4 has so far not been approved for use in screening, although a commercial test, Risk of Ovarian Malignancy Algorithm, ROMA, that combines HE4, CA125II and menopausal status is in use for pre-operative triaging of women [25]. The perfor ...
Global incidence of non-Hodgkin lymphoma
Global incidence of non-Hodgkin lymphoma

... develop breast cancer in their lifetime. This is double the risk of developing lung cancer, the second most common cancer in women.12, 13 Figure 6 Lifetime risk of common female cancers On average one in eight women will develop breast cancer at some time in their lives ...
Summary of the NICE 2015 Suspected Cancer
Summary of the NICE 2015 Suspected Cancer

... • They are based on research undertaken on patients in primary rather than secondary care. • The guidelines are presented in two ways: first by cancer (lung, breast) (page 2 onwards) and then by symptom (abdominal pain, weight loss) (page 17 onwards). • In these new guidelines the threshold for ...
the silent battle within
the silent battle within

... For example, a recently published study involving 76,693 men reported that after 7 to 10 years of follow up, the death rate from Prostate Cancer was very low and that there was no significant difference between the group who had undergone screening with annual PSA testing and DRE (Digital Rectal Exa ...
The Prevalence of Cancer in Quebec in 1999
The Prevalence of Cancer in Quebec in 1999

Cancer Strategy 2014
Cancer Strategy 2014

635 prostate cancer survivors and their
635 prostate cancer survivors and their

... are symptomatic with a late stage disease. The problem with the PSA test is around the timing and extent of treatment when there is a positive PSA test or biopsy. Those problems from over‐treatment come from doctors providing inadequate consultations which can frighten men into treatments that m ...
Acquisition of Chemoresistant Phenotype by
Acquisition of Chemoresistant Phenotype by

... TRPM-2,3 also known as clusterin, sulfated glycoprotein-2, or apolipoprotein J, was first isolated from ram rete testes fluid (3) and has been proposed to have various biological functions, including tissue remodeling, reproduction, lipid transport, and apoptotic cell death (4). TRPM-2 was initially ...
Interventional study for improvement of lung cancer screening rate
Interventional study for improvement of lung cancer screening rate

... about 36,000 men and about 40,000 women for lung cancer screening in Anan City by the following criteria. The extraction was conducted in consideration of age-group. The group was divided into 4 agegroups by 5 years ; age-group 40-44 years, 45-49 years, 50-54 years and 55-59 years. Two-hundred and f ...
Understanding advanced (metastatic) prostate cancer
Understanding advanced (metastatic) prostate cancer

... A specific gene linked to prostate cancer has not yet been identified. However, research has shown that faulty genes that are linked to a higher risk of breast cancer (called BRCA 1 and BRCA 2) may also increase the risk of getting prostate cancer. So, if there’s a strong family history of breast ca ...
Bowel cancer screening: The Facts
Bowel cancer screening: The Facts

... offers screening every two years to all men and women aged 60 to 69. This age range is currently being extended to 60 to 74. People in the invitation age range are automatically sent an invitation, then their screening kit, so they can do the test at home. Your GP will provide your contact details, ...
RESEARCH ARTICLE Colorectal Cancer Risk Factors among the
RESEARCH ARTICLE Colorectal Cancer Risk Factors among the

... Colorectal cancer remains one of the most widespread malignancies in the world. However, there is a lack of comprehensive studies considering colorectal cancer risk factors among Russian populations, particularly in Siberia. The aim of this investigation was to determine the impact of various life ...
Bowel cancer screening: The facts
Bowel cancer screening: The facts

... offers screening every two years to all men and women aged 60 to 69. People in this age group will automatically be sent an invitation, then their screening kit, so they can do the test at home. Your GP will provide your contact details, so it is important that he or she has your correct name and ad ...
Disparities at Presentation, Diagnosis,Treatment, and Survival in African American Men,
Disparities at Presentation, Diagnosis,Treatment, and Survival in African American Men,

Cancer Plan Ghana Ministry of Health
Cancer Plan Ghana Ministry of Health

... These are disturbing indications especially as the country does not seem to be placing itself in readiness to contain these conditions. It is generally noted that early detection and treatment of cancers can drastically reduce the mortality related to these diseases. The cancer plan presents details ...
MAC11686, Understanding advanced (metastatic) prostate cancer
MAC11686, Understanding advanced (metastatic) prostate cancer

... and locally advanced prostate cancer. To order one of these booklets, or if you’re unsure which booklet is suitable for you, call our cancer support specialists on ...
Tumor Markers in Testicular, Prostate, Colorectal, Breast
Tumor Markers in Testicular, Prostate, Colorectal, Breast

... germ cell origin, most of the rest being lymphomas, Leydig or Sertoli cell tumors and mesotheliomas. Germ cell tumors of adolescents and adults are classified into two main types, seminomas and nonseminomatous germ cell cancers of the testis (NSGCT). Testicular cancers represent about 1% of all mali ...
ARLTS1 to Prostate Cancer Susceptibility SANNA SILTANEN
ARLTS1 to Prostate Cancer Susceptibility SANNA SILTANEN

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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