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by Katherine Elizabeth Bright D’Antonio B.S. in Biology, Gettysburg College, 2002
by Katherine Elizabeth Bright D’Antonio B.S. in Biology, Gettysburg College, 2002

Cancer statistics, 2012
Cancer statistics, 2012

... with the exception of American Indians/Alaska Natives, among whom rates have remained stable. The most rapid declines in death rates occurred among African American and Hispanic men (2.4% and 2.3% per year, respectively). Death rates continue to decline for all 4 major cancer sites (lung, colorectum ...
ARLTS1 to Prostate Cancer Susceptibility SANNA SILTANEN
ARLTS1 to Prostate Cancer Susceptibility SANNA SILTANEN

What motivates people with cancer to get active
What motivates people with cancer to get active

... that the number of people living with a cancer diagnosis in 2010 was two million. We know that this number reached 2.5 million in 2015, and is set to rise to four million by 2030. Cancer patients are living longer following diagnosis than they did 40 years ago. Today a cancer diagnosis increasingly ...
Early detection for lung cancer
Early detection for lung cancer

... cancer in their lifetime. In order to maximize the effectiveness of screening, one needs to define the population at the greatest risk. Lung cancer is uncommon among those who are younger than 45 years of age. Incidence rises sharply after age 50. The risk of lung cancer is higher among those who st ...
Bounds in Competing Risks Models and the War on Cancer Bo E
Bounds in Competing Risks Models and the War on Cancer Bo E

... Progress Against Cancer recommended “additional research on how cancer statistics are affected by changes in other causes of death.” This paper derives bounds for aspects of the underlying distributions under a number of different assumptions. Most importantly, we do not assume that cancer and cardi ...
PCA evidence to APPG Inquiry PC Research
PCA evidence to APPG Inquiry PC Research

... Of the £503 million spent by the National Cancer Research Institute partners (NCRI) in 2013, only £5 million was spent on pancreatic cancer. In contrast, breast cancer received £40 million, bowel cancer, £25 million, leukaemia £34 million, and Prostate £22 million. The criteria to become a member of ...
Pomegranate - His Wondrous Works
Pomegranate - His Wondrous Works

Does This Patient Have a Family History of Cancer?
Does This Patient Have a Family History of Cancer?

... Several organizations have recommended initiating screening earlier, more frequently, or both in patients at moderately increased risk of developing cancer based on their family history.18-27 Guidelines have also been published regarding the management of individuals who are at high cancer risk.26,2 ...
Advanced prostate cancer Managing symptoms and getting support
Advanced prostate cancer Managing symptoms and getting support

THe RicH PiCtuRE - Macmillan Cancer Support
THe RicH PiCtuRE - Macmillan Cancer Support

... Macmillan or any other organisation referenced in this document claim no responsibility for how third parties use the information contained in this document. We have endeavoured to include all the major data available to us as of July 2014, but a document of this nature (essentially a summary of a l ...
Characterization of the CA 125 Antigen
Characterization of the CA 125 Antigen

... of the composite gels were also those of Laemmli (14). Immunoblotting. After electrophoresis the proteins were electrophoretically transferred to nitrocellulose [Towbin et al., (15)], ¡mimmo blotted with radiolabeled OC 125, and autoradiographed. Each imum noblot contained at least one negative ant ...
CANCER RESOURCE CENTRE LIBRARY BOOK LIST
CANCER RESOURCE CENTRE LIBRARY BOOK LIST

... Stewart B. Fleishman, MD Sheldon G. Sheps, MD Stephen E. Langer MD; James Scheer Robert J. Heller Dennis R. Dinger Robert Rykovich Marilyn Haas; Deborah McBride Cynthia Chauhan Shawn Achor Barbara L Fredrickson, Ph.D. Cynthia Chauhan ...
Rectal Cancer
Rectal Cancer

... factors symptoms signs, colorectal cancer patient version national cancer institute information about colon and rectal cancer treatment prevention genetics causes screening statistics and other topics from the national cancer institute, colorectal cancer american cancer society - the american cancer ...
Cancer Aspirin or Nonsteroidal Anti- inflammatory Drugs for the Primary
Cancer Aspirin or Nonsteroidal Anti- inflammatory Drugs for the Primary

Prostate cancer: diagnosis and treatment
Prostate cancer: diagnosis and treatment

... response to a request from the Department of Health (DH). They approve topics for guideline development and before deciding whether to refer a particular topic to the National Institute for Health and Clinical Excellence (NICE) they consult with the relevant patient bodies, professional organisation ...
Prostate cancer risk regions at 8q24 and 17q24 are differentially
Prostate cancer risk regions at 8q24 and 17q24 are differentially

... issues were considered in supplemental analyses. First, we checked for potential bias that may have occurred in the course of subsampling tumor materials. For this question, risk allele frequencies for all 27 loci were compared between somatically phenotyped cases (n = 552) and the 8,129 non-phenoty ...
mechanisms of therapeutic resistance in castration resistant prostate
mechanisms of therapeutic resistance in castration resistant prostate

... proliferate again in the absence of male steroid hormones and this represents a much more aggressive disease state. Biochemical recurrence can be monitored in patients by sequential evaluation of serum prostate specific antigen (PSA); nearly 70,000 American men develop this biochemical recurrence pe ...
Working with cancer
Working with cancer

... support may be needed over many years after the initial diagnosis as they continue to live with the physical and emotional impacts of cancer. For people living with metastatic cancer, the most advanced stage of cancer, support needs are likely to be ongoing. It’s important for employers to take a ho ...
cancer prevention and interception: a new era for chemopreventive
cancer prevention and interception: a new era for chemopreventive

... model [2], where we weigh the risks of undesired effects associated with a specific chemopreventive molecule versus its potential preventive effect in decreasing the risk of getting cancer (Figure 2). As the individual cancer risk increases (due to genetic, metabolic, carcinogenic behaviors or expos ...
Dietary Lycopene Modulates Prostate Cancer Biomarker Genes in
Dietary Lycopene Modulates Prostate Cancer Biomarker Genes in

... approximately 1,444,920 new cancer cases are expected to be diagnosed as well as 559,650 anticipated cancer-related deaths. The survival rate of cancer has risen to 66% during 1996 to 2002 compared to 51% in 1975 to 1977 due in part to screening, early detection and improved therapies. However, amon ...
Costing statement: Suspected cancer
Costing statement: Suspected cancer

... This guideline is anticipated to increase the number of diagnostics tests and referrals for suspected cancer significantly and this will have cost implications. However at the same time benefits are anticipated from earlier diagnosis of cancer, a reduction in the number of patients with cancer ident ...
1 - Be Seen, Get Screened
1 - Be Seen, Get Screened

Increased cancer burden among pesticide
Increased cancer burden among pesticide

... Pest problems in public health (ie, vectors of disease), agriculture, and commerce are not static because pests develop resistance to widely used pesticides and are periodically introduced to new geographic areas without effective natural controls. Historically, the evolution of new pests has result ...
Colorectal Cancer: An Overview of the Epidemiology - C
Colorectal Cancer: An Overview of the Epidemiology - C

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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