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Silence 1(1):6
Silence 1(1):6

Advanced prostate cancer Managing symptoms and getting support
Advanced prostate cancer Managing symptoms and getting support

... treated, the easier it will be to control. Different types of pain are treated in different ways. To find the right way to deal with it, you might have a pain assessment and be referred to a palliative care specialist. Treatments to control pain include: • treatment for the cancer itself, such as h ...
Development of the human cancer microRNA network Open Access
Development of the human cancer microRNA network Open Access

A Checklist for Ascertaining Study Cohorts in Oncology
A Checklist for Ascertaining Study Cohorts in Oncology

... Step 1 of the checklist emphasizes the importance of understanding the biology, natural history, and etiology of the specific cancer of interest prior to establishing the inclusion/exclusion criteria of the study protocol. Knowledge of the natural history of the disease will facilitate an understand ...
14-3-3 Proteins Modulate the ETS Transcription Factor ETV1 in
14-3-3 Proteins Modulate the ETS Transcription Factor ETV1 in

... Identification of novel ETV1 interaction partners To identify novel ETV1 cofactors, we fused ETV1 to two affinity tags, expressed it in 293T cells and isolated native protein complexes containing ETV1 by two consecutive affinity purifications. Subsequent mass spectrometry identified 6 different 14-3-3 pr ...
Workshop on imaging science development for cancer prevention
Workshop on imaging science development for cancer prevention

... biomarker assessment methodologies as each developer negotiates the hurdles and challenges along various engineering, clinical, and regulatory routes to the marketplace. A workshop convened by the National Cancer Institute (NCI) Cancer Imaging Program in Gaithersburg, MD, provided an overview of the ...
elevated Plasma Vitamin B12 levels as a Marker
elevated Plasma Vitamin B12 levels as a Marker

... The LABKA database (20) contains all test results from routine tests performed in hospital laboratories in Northern Denmark, which has a total population of 2.2 million inhabitants. Results of more than 1700 different types of analyses are included in the database. For each analysis, the database st ...
Profiling of High-risk Prostate Cancer Families in Finland SANNA PAKKANEN
Profiling of High-risk Prostate Cancer Families in Finland SANNA PAKKANEN

Cancer screening in the United States, 2014: A review of current
Cancer screening in the United States, 2014: A review of current

... screening examination. When CBE is performed in women of any age, it is an opportunity to discuss the value of early breast cancer detection and answer any questions a woman may have about her own risk, other issues related to breast disease, and questions related to conventional or new imaging tech ...
3.2 West Africa
3.2 West Africa

... liver (4.2%). Because of the different age distributions, the agestandardized incidence for cervix cancer (26.8 per 100 000) is rather higher than that for breast cancer (21.4 per 100 000); liver cancer has the third highest incidence (5.6 per 100 OOO), followed by stomach cancer (4.5 per 100 000). ...
MINI-REVIEW Update knowledge on cervical cancer incidence and
MINI-REVIEW Update knowledge on cervical cancer incidence and

... cultures in Muslim societies. This reduction is attributed to male circumcision; studies show that male circumcision in Muslim societies reduces risk of HPV infection (Kjaer et al., 1991). More than 80% of cervical cancers are found in India and China (Rai et al., 2014; Li et al., 2013). An estimate ...
David John Waters - Purdue University
David John Waters - Purdue University

... Meiers I, Waters DJ, Bostwick DG. Preoperative prediction of multifocal prostate cancer and application of focal therapy. Urology 2007; 70(6 Suppl): 3-8. Waters DJ, Shen S, Xu H, Kengeri SS, Cooley DM, Chiang EC, Chen Y, Schlittler D, Oteham C, Combs GF Jr, Glickman LT, Morris JS, Bostwick DG. Nonin ...
ERG protein expression reflects hormonal treatment response and is
ERG protein expression reflects hormonal treatment response and is

... Background: ERG (ETS regulated gene) protein expression has been shown to reflect ERG genomic rearrangements in prostate cancer (PCA). However, ERG protein expression prognostic value has not been yet investigated. Design: ERG protein expression was investigated in a cohort of 312 men with PCA diagno ...
Genetic Epidemiology of Hereditary Prostate Cancer in Finland
Genetic Epidemiology of Hereditary Prostate Cancer in Finland

... Family history is one of the strongest risk factors for prostate cancer. Five to ten percent of prostate cancers may be strongly influenced by inherited genetic defects. The aim of this study was to search for genetic risk factors and susceptibility genes for human prostate cancer in Finland using e ...
Pancreatic Cancer - The Indonesian Journal of Gastroenterology
Pancreatic Cancer - The Indonesian Journal of Gastroenterology

The Cancer Burden in New Jersey
The Cancer Burden in New Jersey

... Cancer takes a devastating toll on New Jersey. Nationally, one in two men and one in three women will get a cancer diagnosis in their lifetimes. More than half of all these diagnoses will occur after the age of 65.2 Yet while specific issues have been addressed and the New Jersey Department of Healt ...
ACR Appropriateness Criteria® External Beam Radiation Therapy
ACR Appropriateness Criteria® External Beam Radiation Therapy

... years old at treatment died of prostate cancer nearly 3 times more frequently than of other causes when they were radiated to 70 Gy, whereas those treated to 78 Gy died of other causes more frequently. Patients age 70 or older treated to 70 Gy died of prostate cancer as often as other causes, and th ...
Cancer Statistics, 2010
Cancer Statistics, 2010

... Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data regarding cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, the Centers f ...
Characteristics and predictors of fatigue among men
Characteristics and predictors of fatigue among men

... with ADT have been reported to experience clinically significant fatigue [8]. Although these studies provide useful information, they are characterized by a number of methodologic limitations that include small sample sizes, limited follow-up periods, lack of a non-cancer comparison group, and/or la ...
Print this article - Society for Science and Education
Print this article - Society for Science and Education

PREVENTATIVE CARE SCREENNG GUIDELINES
PREVENTATIVE CARE SCREENNG GUIDELINES

... a father or brother who had prostate cancer before age 65, should have this talk with a doctor starting at age 45. Testing includes the PSA blood test with or without a rectal exam. How often they are tested will depend on their PSA level.  AUA – may start screening as young as age 40 with PSA and ...


Cancer Statistics, 2009
Cancer Statistics, 2009

... Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, Centers for Disease ...
Opportunistic Gastric Cancer Screening in Korea (2005
Opportunistic Gastric Cancer Screening in Korea (2005

... Methods: Data from 8,160 men and women ages >40 years from the 2005 to 2009 Korean National Cancer Screening Survey were used to analyze the relationship between socioeconomic position and receiving upper gastrointestinal series or upper endoscopy within the past 2 years. We used absolute and relati ...
Prostate Cancer Program Program Code: 3 Section 8.1.5
Prostate Cancer Program Program Code: 3 Section 8.1.5

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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