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Friday - World Cancer Congress
Friday - World Cancer Congress

2013-2014 Cancer Facts & Figures for African Americans
2013-2014 Cancer Facts & Figures for African Americans

Pathways Managing Cancer Workplace
Pathways Managing Cancer Workplace

The Big `C`: Quantifying the social and economic impact
The Big `C`: Quantifying the social and economic impact

... the body, transported by the blood or lymph system. When this happens new tumours can form elsewhere in the body. ...
New Brunswick Cancer Network Cancer System Performance 2012
New Brunswick Cancer Network Cancer System Performance 2012

... Regional Manager ‑ Performance Measurement Vitalité Health Network ...
View - Griffith Research Online
View - Griffith Research Online

... predictive factors that are associated with better breast cancer survival include being aged 40-69 years old at diagnosis, lower tumour grade (well-differentiated), absence of comorbidities (such as cardiovascular disease, diabetes and other cancers), favourable genetic profile, human epidermal grow ...
Cancer - Blackburn with Darwen Council
Cancer - Blackburn with Darwen Council

... In non-smokers, cancer mortality is 40% higher among obese than non-obese31, and 10% of cancer deaths are obesity-related.32 Controversial, but thought to account for 4.7% of new cases each year.30 Incidence and mortality generally higher in deprived groups (breast cancer an exception).33 Could save ...
12.04.504 Genetic Testing for Hereditary Breast / Ovarian Cancer
12.04.504 Genetic Testing for Hereditary Breast / Ovarian Cancer

... assess clinical validity of mutation testing. In high-risk women with positive test results, cumulative risks for developing breast cancer by age 70 were 46% for BRCA1 and 50% for BRCA2 when a single family member is tested, and 70% for BRCA1 and 71% for BRCA2 when multiple family members are teste ...
Prostate Cancer
Prostate Cancer

Cancer Statistics
Cancer Statistics

... Incidence rates for prostate cancer peaked in 1992, but have remained high due to increased detection through the PSA (prostate specific antigen) test. Female breast cancer incidence rates have remained steady since the late 1980’s. Mammography screening has played an important role in the early dia ...
michael_donaldson200..
michael_donaldson200..

Clinical Policy Bulletin: Tumor Markers
Clinical Policy Bulletin: Tumor Markers

Cancer in Ontario: Overview
Cancer in Ontario: Overview

... needs over the course of their lifespan. The real celebration here is that we are seeing improved survival across all age groups. Among the most dramatically improved is prostate cancer, which results at least partly from the bias of identifying slow-growing disease earlier. This leads to genuine co ...
colorectal cancer - NurseCe4Less.com
colorectal cancer - NurseCe4Less.com

... basically, caused by activation of oncogenes and inactivation of tumor suppressor genes. This leads to a progressive alteration and instability of the genetic material of the epithelial cells of the colon.24 This genetic instability and alteration takes two basic forms: chromosomal instability (CIN) ...
The Emotional Impact Of Cancer
The Emotional Impact Of Cancer

... needed to enable people whose cancers are cured, in remission or still being treated to live an acceptable life. Quantity of life for many cancer patients is improving steadily; now we need to do the same for quality of life. The new cancer plans needed for all four nations of the UK must take this ...
Lung cancer screening by low-dose spiral computed tomography
Lung cancer screening by low-dose spiral computed tomography

Cancer survival in Europe 1999–2007 by country and
Cancer survival in Europe 1999–2007 by country and

... colon, and lung cancers. Survival for lung cancer in the UK and Ireland was much lower than for other regions for all periods, although results for lung cancer in some regions (central and eastern Europe) might be affected by overestimation. Survival usually decreased with age, although to different ...
Cancer survival in Europe 1999–2007 by country and
Cancer survival in Europe 1999–2007 by country and

... colon, and lung cancers. Survival for lung cancer in the UK and Ireland was much lower than for other regions for all periods, although results for lung cancer in some regions (central and eastern Europe) might be affected by overestimation. Survival usually decreased with age, although to different ...
REVIEW Physical Activity and its Relation to Cancer Risk: Updating
REVIEW Physical Activity and its Relation to Cancer Risk: Updating

... to the Second Expert Report (WCRF/AICR, 2007) the scientific evidence shows that for adults “engage in at least 30 minutes of moderate to vigorous physical activity, in addition to usual activities, on 5 or more days of the week” by adults may reduce not only the risk of certain cancers, heart disea ...
Overcoming Cancer in the 21st Century
Overcoming Cancer in the 21st Century

... sites and cell types (seen from this perspective, cancer comprises over 200 distinct conditions that fall into half a dozen main categories – see Box 1) but also a wide variety of complex molecular, acquired epigenetic (gene ...
Overcoming Cancer in the 21st Century
Overcoming Cancer in the 21st Century

Pomegranate Reverses Atherosclerosis and Slows
Pomegranate Reverses Atherosclerosis and Slows

Global Patterns of Cancer Incidence and Mortality Rates and Trends
Global Patterns of Cancer Incidence and Mortality Rates and Trends

... decrease in the incidence rates (60, 61). Similar decreasing trends, in part due to reduction in the use of menopausal hormone therapy, have also been noted in many other western countries, including the United Kingdom, France, and Australia (62-64). In contrast to the incidence trends, breast cance ...
Cancer Prevention, Screening, and Early Detection
Cancer Prevention, Screening, and Early Detection

... studies pointed to smoking and its association with cancer (Koh, Kannler, & Geller, 2001; Lombard & Doering, 1928). Research culminated with the 1964 U.S. Surgeon General’s report, which concluded that smoking was the major cause of lung cancer and was associated with oral and laryngeal cancers in m ...
THE ROLE OF THE EPITHELIAL-MESENCHYMAL TRANSITION IN AGGRESSIVE TUMOUR PHENOTYPES
THE ROLE OF THE EPITHELIAL-MESENCHYMAL TRANSITION IN AGGRESSIVE TUMOUR PHENOTYPES

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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