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NBN gene - MyriadPro
NBN gene - MyriadPro

Localized Prostate Cancer 10 year outcomes
Localized Prostate Cancer 10 year outcomes

... alone, an estimated 180,890 cases will be diagnosed in 2016, and 26,120 men will die from the disease.1 The widespread use of PSA testing has resulted in a dramatic increase in the diagnosis and treatment of prostate cancer, but many men do not benefit from intervention because the disease is either ...
Tumor Markers
Tumor Markers

... Determining prognosis for certain cancers Seeing if certain treatments are likely to work Seeing how well treatment is working Looking for recurrent cancer ...
EPIDEMIOLOGY AND GENETICS OF FAMILIAL CANCER Kari
EPIDEMIOLOGY AND GENETICS OF FAMILIAL CANCER Kari

... somewhat more than 10% of all cancers are familial, i.e., at least 2 first-degree relatives are diagnosed with the same cancer. However, because of low penetrance, sex-specific cancers and small families, this figure is scientifically an underestimate of the scope of familial risk, and psychological ...
Battling a “Silent Killer”
Battling a “Silent Killer”

SCIENTIFIC PROGRAM
SCIENTIFIC PROGRAM

to the PDF file.
to the PDF file.

... Unlike adult cancer the childhood cancer response better with chemo so can be cured if screened on time. ...
A Church Based Program On Prostate Cancer Screening For African
A Church Based Program On Prostate Cancer Screening For African

Advanced prostate cancer optimising and integrating care
Advanced prostate cancer optimising and integrating care

... remains uncertain, but there is an increasing number of therapy options for use on a sequential basis. The order and combination of therapies may depend upon the patient’s age, performance status, relevant comorbid conditions, prostatespecific antigen (PSA) kinetics or site of progression and whethe ...
Contemporary Use of Initial Active Surveillance Among Men in
Contemporary Use of Initial Active Surveillance Among Men in

... prostate-specific antigen (PSA)-based screening for early detection of prostate cancer [5], as well as efforts to unlink screening and treatment in the care of men with early-stage tumors [6,7]. Supporters of the latter approach have called for greater use of initial active surveillance (AS) with se ...
A simple method to estimate survival trajectories across time in
A simple method to estimate survival trajectories across time in

... • May be diagnosed with incurable disease (e.g. Lung) • May initially be treated curatively, and then relapse (e.g Breast) • Once diagnosed with “incurable” disease, may still be treated and live for many years CRUK Cancer Stats (2015) ...
Prostate Cancer - Yale Cancer Center
Prostate Cancer - Yale Cancer Center

... see if we can actually diagnose either a malignancy or some other abnormality in that population, and you really have to differentiate between early detection in a population. This is particularly relevant in prostate cancer because it is such a heterogenous disease, and recently there has been a lo ...
J. Coll.of Med. June 2010 15 (1) - International Journal of Research
J. Coll.of Med. June 2010 15 (1) - International Journal of Research

... hepatocellular carcinoma (HCC) screening continues to be debated. Retrospective studies11,12 in Asia showed improved survival with AFP screening but the findings have not been confirmed in other studies. In spite of this, most hepatologists use periodic AFP and ultrasound screening in high risk pati ...
1 The Göteborg-2 trial A prospective, randomized
1 The Göteborg-2 trial A prospective, randomized

... elderly men. Therefore, the major dilemma with current screening is the high risk of overdiagnosis (30-50%) i.e. detection of small very slow-growing, insignificant tumors, that would never have given rise to clinical symptoms during a man’s life-time.(Draisma 2003). Moreover, the PSA test is a sens ...
review request for
review request for

... Serum testosterone level less than 50 ng/dl (17 nmol/l) Progressive disease based on (check all that apply): Serum prostate-specific antigen (PSA) level of greater than or equal to 5 ng/ml Evidence of progressively increasing PSA values Osseous metastases on imaging with objective evidence of progr ...
Testosterone replacement in prostate cancer survivors
Testosterone replacement in prostate cancer survivors

... of men with high-risk high-grade disease, and even patients with metastatic disease at presentation. In most cases, stopping TRT resulted in rapid and dramatic declines in PSA level, such that most men did not need to receive immediate anti-neoplastic therapy. Further studies to identify the clinica ...
Minutes PPG Mtg 14th June 2016
Minutes PPG Mtg 14th June 2016

... This is used in hormone related disease such as breast and prostate cancer and works on Oestrogen/Progesterone balance. The most well-known of these is Tamoxifen. It may potentially be used for bowel cancer. Radioactive Isotopes Used mainly in liquid form these days for thyroid cancers and also lung ...
THE ROLE OF TAMOXIFEN IN REDUCING BICALUTAMIDE‐INDUCED
THE ROLE OF TAMOXIFEN IN REDUCING BICALUTAMIDE‐INDUCED

Managing Uncertainty and Coping with a Cancer
Managing Uncertainty and Coping with a Cancer

... • Emotions are a signal, they are intended to provide useful information. • Emotions are just one of our methods of perception. • Emotions can come out of nowhere, they can be completely contrary to whatever event one is currently experiencing. ...
cardiology patient page
cardiology patient page

... are diagnosed at an early stage. Over the past several decades, the 5-year median survival of patients with prostate cancer has increased to more than 99%, largely owing to both the improvements in early diagnosis and innovations in treatment. As a result, there are nearly 3 million prostate cancer ...
The Act Smart Campaign - Survivors Celebration Breakfast
The Act Smart Campaign - Survivors Celebration Breakfast

Treatment of metastatic prostate cancer
Treatment of metastatic prostate cancer

... shown to improve overall survival when given following docetaxel and in chemotherapy-naïve patients, where it has been shown to reduce the risk of death by 30% (HR 0.70; CI 0.59-0.83, p<0.0001).11,12 Additional benefits include a significant delay in the time to first skeletal-related events includi ...
Colon cancer screening and minority health
Colon cancer screening and minority health

... 3: For men ages 55 to 69 years the Panel recognizes that the decision to undergo PSA screening involves weighing the benefits of preventing prostate cancer mortality in 1 man for every 1,000 men screened over a decade against the known potential harms associated with screening and treatment. For thi ...
NPCR Education and Training Series (NETS) Module10: Male Genitourinary Malignancies
NPCR Education and Training Series (NETS) Module10: Male Genitourinary Malignancies

Outreach Strategies: Reaching African American Men in
Outreach Strategies: Reaching African American Men in

... cancer death in African American men behind lung cancer. African American men have a 20% higher incidence rate and a 40% higher death rate from all cancers combine than white men! In Maryland, the Prostate cancer death rate was 71.7% for 19972001 which is higher than the national average of 70.4%. T ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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