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Top ten cancer facts everyone should know
Top ten cancer facts everyone should know

... 9. Processed meats (bacon, sausages, preserved meats) are now also classed as a carcinogen by the World Health Organisation, and moderation is advised. Red meat is only a “probable” ...
Gene Section SEPP1 (selenoprotein P, plasma, 1) Atlas of Genetics and Cytogenetics
Gene Section SEPP1 (selenoprotein P, plasma, 1) Atlas of Genetics and Cytogenetics

Novel T-cell Targets for Cancer Immunotherapies
Novel T-cell Targets for Cancer Immunotherapies

DELIVER IMAGING BIOMARKERS INTO THE CLINIC at
DELIVER IMAGING BIOMARKERS INTO THE CLINIC at

... DW-MRI ...
Full Text - Journal of American Science
Full Text - Journal of American Science

... (MTX) in patients with metastatic CRPC that progresses after docetaxel. A PSA decrease ≥50% was recorded in 15 of 58 evaluable patients (25.86%), and objective partial response in 3 (18%) and stable disease in 4 (24%) of 17 patients with measurable disease. Disease progressed in 10 patients (59%). P ...
Updates in TNM Staging of Prostate Cancer
Updates in TNM Staging of Prostate Cancer

... Andreoiu M, Cheng L. Multifocal prostate cancer: biologic, prognostic, and therapeutic implications. Hum Pathol. 2010;41(6):781-793. Ayala AG, Ro JY, Babaian R, et al. The prostatic capsule: does it exist? Its importance in the staging and treatment of prostatic carcinoma. Am J Surg Pathol. 1989;13( ...
May 2015 - PCCN Markham
May 2015 - PCCN Markham

The Royal Australian and New Zealand College of
The Royal Australian and New Zealand College of

... 5. Don’t routinely use extensive locoregional therapy in most cancer situations where there is metastatic disease and minimal symptoms attributable to the primary tumour. In the past, extensive local regional therapies (e.g., surgery) were often provided in patients with metastatic disease, regardle ...
Hormone therapy in the management of prostate cancer: treating the
Hormone therapy in the management of prostate cancer: treating the

... and only 13.8% had received radical treatment. It is disturbing to know that in localized disease early HT is not only inefficient but can lead to a paradoxical increase in mortality. This was clearly demonstrated by the EPC trial that included 8,113 men with non-metastatic PCa (all M0) to assess th ...
Chemotherapy in Prostate Cancer: A Guide for Patients
Chemotherapy in Prostate Cancer: A Guide for Patients

... treatment or pain medication tends to cause constipation. Other benefits of high fibre foods include control of cholesterol and blood sugar. Fruits and vegetables contain fibre but it is important to include high fibre cereals (such as oatmeal or bran flakes), whole wheat breads, and other grain pro ...
Final Protocol - Medical Services Advisory Committee
Final Protocol - Medical Services Advisory Committee

... swellings, hardenings or lumps may be signs of prostate cancer. The Applicant advises that the DRE has a low sensitivity, although its positive predictive value is high – hard lumps detected by DRE are very likely to be prostate cancer, and while chronic inflammatory conditions can cause hard lumps, ...
Early Prostate Cancer Translational Research Initiative Planning
Early Prostate Cancer Translational Research Initiative Planning

... and one-third of patients are under-treated. The goal is to sub-stage this group for improved surveillance and to identify those patients who require more intensive therapy; To date, 305 prostate whole genomes have been sequenced; In some patients, they have found two genetically distinct prostate c ...
Thursday, January 21st, 2010 7 - 9 P.M. Dr. Anne Katz, Clinical
Thursday, January 21st, 2010 7 - 9 P.M. Dr. Anne Katz, Clinical

... for regular PSA (prostate specific antigen) testing and watching the PSA doubling time, as well as periodically having the patient undergo biopsies. Doctors then treat only those patients whose cancer is reclassified over time as higher risk. In this study, 30 per cent of the patients were reclassif ...
OVAC Cancer Prevention Fact Sheet
OVAC Cancer Prevention Fact Sheet

... CRC, educate health care providers about CRC screening guidelines and assist state programs with CRC screening programs. The CDC supports critical state and local comprehensive cancer control programs in all 50 states and DC. CDC programs fund a range of services including tobacco, prostate, and ski ...
Hormone Deprivation Therapy
Hormone Deprivation Therapy

... You will need to order your vacuum device through your GP - order code XX-50 PIP code 289-0713 – discuss with your consultant or nurse specialist at your next appointment. If you have tried PDE5 inhibitors with no effect you may wish to try penile injections or urethral pellets/gel under the guidanc ...
Defining and predicting indolent and low risk prostate cancer - e-ESO
Defining and predicting indolent and low risk prostate cancer - e-ESO

... 3. Current nomograms predicting indolent cancer are integrated in risk assessment strategies The development of nomograms to predict the outcome of disease treatments has been stimulated by the growth of clinical databases overtime. Nomograms are of interest to inform patients, and support them maki ...
Module 5 PowerPoint Slides - The Cancer 101 Curriculum
Module 5 PowerPoint Slides - The Cancer 101 Curriculum

... person who does not have any symptoms is called screening. ...
Statistics on Cancer Incidence 2015
Statistics on Cancer Incidence 2015

... Statistics on Cancer Incidence 2015 In 2015, approximately 65,000 malignant tumors, for around 61,000 individuals, were reported to the Swedish Cancer Registry. The distribution between men and women is relatively even. The most common form of cancer among women is breast cancer, while prostate canc ...
Active Surveillance for Low-risk Prostate Cancer
Active Surveillance for Low-risk Prostate Cancer

... cancer compared with non-AAM, signifying a potential need for closer follow-up and more stringent enrollment criteria in AAM. UROLOGY 83: 364e368, 2014.  2014 Elsevier Inc. ...
It May Not Save Your Life Why there`s more reason than ever to be
It May Not Save Your Life Why there`s more reason than ever to be

CWR22: The First Human Prostate Cancer Xenograft with Strongly
CWR22: The First Human Prostate Cancer Xenograft with Strongly

... castration of animals that bear CWR22, serum PSA has fallen 153080-fold; in all but one animal, >50-fold. Physically measurable recurrence is preceded by an elevation of serum PSA. The general availability of this model will offer a unique opportunity to compare a human prostate cancer that regresse ...
Understanding cancer PowerPoint (short version)
Understanding cancer PowerPoint (short version)

... Why screening tests and self-exams ...
Prostate Cancer and Management and Referral Guidance
Prostate Cancer and Management and Referral Guidance

... prostatitis, urethritis, cystitis, and proctitis. • The later risks of radiation therapy include erectile dysfunction, rectal bleeding and lower urinary tract symptoms. ...
VEGFR-1 Overexpression Identifies a Small Subgroup of Aggressive
VEGFR-1 Overexpression Identifies a Small Subgroup of Aggressive

... VEGFR-1 expression was found in 32.6% of 2669 interpretable prostate cancers, indicating that VEGFR-1 can be activated in a fraction of secretory cells as a consequence of malignant transformation. The frequency of detectable VEGFR-1 staining is substantially lower in our study than in four earlier ...
Multi-parametric MRI scans prior to biopsy for improving diagnosis of
Multi-parametric MRI scans prior to biopsy for improving diagnosis of

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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