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The relationship between cancer incidence
The relationship between cancer incidence

... be inferred from Figure 1, as the relative risk of distant-stage thyroid cancer is close to 1, with wide confidence intervals indicating rarity, while local-stage thyroid cancer is centered below 0.7, with narrow confidence intervals indicating it is more common. Figure 2, however, shows the relati ...
RISK FACTORS FOR CANCER
RISK FACTORS FOR CANCER

Chemohormonal Therapy in Metastatic Hormone
Chemohormonal Therapy in Metastatic Hormone

... with an elevated prostate-specific antigen (PSA) level; radiologic evidence of metastatic disease; and an ECOG performance-status score of 0, 1, or 2 (on a scale from 0 to 5, with higher scores indicating greater disability; patients with a score of 2 were eligible if the decrement in functioning wa ...
The unfolded protein response during prostate cancer development
The unfolded protein response during prostate cancer development

... followed by invasive adenocarcinoma with metastatic potential (cancer). Using these animals, Gao et al. [11] had elaborately profiled the gene expression patterns of prostate epithelial cells harvested from distinct prostate cancer stages: normal prostate, dysplasia, LGPIN, HGPIN, cancer, androgen-i ...
NIH Public Access
NIH Public Access

... and cell lysates were prepared for Western blot analysis. Our results suggested that the treatment of BME led to a significant downregulation of cyclin D1 and cyclin E in prostate cancer cell lines (Fig. 2A). We have also observed a significant increase of p21 protein in both the prostate cancer cel ...
PDF - Theranostics
PDF - Theranostics

... Exclusion criteria were neoadjuvant androgen deprivation therapy and previously performed transurethral resection of the prostate. MpMRI was not mandated in the original trial protocol, but was also performed in 7 patients. Mean patient age was 64 years (range 52-74) and mean serum PSA at imaging wa ...
chapter 110 - Treatment of Castration
chapter 110 - Treatment of Castration

How much do you know about colorectal cancer?
How much do you know about colorectal cancer?

... • How common is colorectal cancer in Alberta? (i.e. 1 in X men and 1 in X women)? • How many cases of colorectal cancer can be treated successfully if found early (i.e. X out of 10)? • Does a diet rich in fruits and vegetables help reduce risk of colorectal cancer? • What is a FIT home stool test ch ...
Operator Dependent Choice of Prostate Cancer
Operator Dependent Choice of Prostate Cancer

Stage 4 colon cancer symptoms before death
Stage 4 colon cancer symptoms before death

... Overview. What Is It? Colon cancer is cancer of the large intestine or the rectum, and is often called colorectal cancer. Colorectal cancer is one of the most common. Symptoms of final stage colon cancer can vary, and they typically depend on the areas of the body affected by the cancer. Abdominal p ...
Overexpression of enhancer of zeste homolog 2
Overexpression of enhancer of zeste homolog 2

... cancer. EZH2 expression was analyzed by immunohistochemistry on a tissue microarray containing more than 12 400 prostate cancer specimens. Results were compared to tumor phenotype, biochemical recurrence and molecular subtypes defined by ERG status as well as genomic deletions of 3p, 5q, 6q and PTEN ...
sp i ll l
sp i ll l

Management of the prostate and urethra in patients undergoing
Management of the prostate and urethra in patients undergoing

... topics in urologic oncology. Those in favor of it emphasize substantial improvements in functional outcomes and the effect that it could have on patients’ quality of life. Those opposed to it are sceptical of the perceived increased oncologic risk and violation the oncologic principle of en bloc exc ...
Andie MacDowell On Beating Cancer Golden Globe Nominee
Andie MacDowell On Beating Cancer Golden Globe Nominee

Discovery Newsletter Volume2 Autumn2005
Discovery Newsletter Volume2 Autumn2005

PREDICTING PROSTATE CANCER
PREDICTING PROSTATE CANCER

... whereby men who would otherwise be unaffected by a relatively benign untreated prostate cancer run the risk of having unwanted side effects from invasive diagnostic procedures and treatments. In order to improve this situation, better tools for detection of prostate cancer are urgently needed. A num ...
Prostate Cancer and Socioeconomic Status in the Finnish
Prostate Cancer and Socioeconomic Status in the Finnish

... However, PC mortality does not show a similar gradient, and PC survival is poorer among men with lower SES (17–19). Men with low SES may have lower health literacy and awareness, and they may perceive cancer screening tests as more threatening, more difficult to accomplish, and less beneficial (20). I ...
Prostate Cancer and Socioeconomic Status in the Finnish
Prostate Cancer and Socioeconomic Status in the Finnish

... However, PC mortality does not show a similar gradient, and PC survival is poorer among men with lower SES (17–19). Men with low SES may have lower health literacy and awareness, and they may perceive cancer screening tests as more threatening, more difficult to accomplish, and less beneficial (20). I ...
Results from the Prostrate Cancer Prevention Trial
Results from the Prostrate Cancer Prevention Trial

... risk factors differ for low-grade compared with high-grade prostate cancer, which would not be evident in a combined analysis; Second, given the low number of high-grade cancers, the findings for total differ little from those of lowgrade cancer alone. Associations of fatty acids with cancer risk di ...
HDR Brachytherapy
HDR Brachytherapy

Prostate cancer A guide for newly diagnosed men
Prostate cancer A guide for newly diagnosed men

C-Change Complete Listing of Cancer Core Competency Standards
C-Change Complete Listing of Cancer Core Competency Standards

... a) Explain how cancer pain differs from other types of pain. b) Describe the methods used to diagnosis cancer pain throughout the progression of the disease. c) Differentiate between acute and chronic pain symptoms. d) Describe the characteristics used to assess cancer pain: frequency, intensity, an ...
What is cancer? 1 - National Aboriginal Health Organization
What is cancer? 1 - National Aboriginal Health Organization

... • Mesothelioma - a cancer caused by asbestos • Skin cancer - caused by UV rays from the sun ...
Modeling prostate cancer detection probability using
Modeling prostate cancer detection probability using

... cores against saturation biopsy techniques, or indeed biopsies from radical prostatectomy ...
MEDIA BACKGROUNDER: COLON CANCER Colon cancer Colon
MEDIA BACKGROUNDER: COLON CANCER Colon cancer Colon

... developing the disease. These individuals should be checked with a colonoscopy (instead of an FOBT) beginning at age 50, or 10 years earlier than the age their relative was diagnosed, whichever comes first. Some people who have had polyps removed from their colon, as well as people with inflammatory ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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