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The Bone Scan Index - Clinical Cancer Research
The Bone Scan Index - Clinical Cancer Research

... present at baseline and to monitor the tumor’s response to therapy. In contrast to the important of bone ...
Imaging of Prostate Carcinoma
Imaging of Prostate Carcinoma

... clinical practice. It is hoped that these novel imaging methods will be superior to the current standard means in assessing mortality, tumor size, and therapeutic response to targeted therapies. This review focuses on the main imaging methods and their use for these purposes. The National Comprehens ...
Arai et al (2009) found a linear, positive - DSpace
Arai et al (2009) found a linear, positive - DSpace

course syllabus
course syllabus

... 6. progress in the diagnosis and treatment of common human cancers You will develop your own opinion about: 1. whether environmental safeguards are sufficient to protect us from cancer 2. whether the health care industry serves the needs of cancer patients 3. whether promising new drugs should be ma ...
on Colorectal Cancer
on Colorectal Cancer

(MDT) Guidance for Managing Prostate Cancer
(MDT) Guidance for Managing Prostate Cancer

... • PSA is a kallikrein-like serine protease produced almost exclusively by the epithelial cells of the prostate. ...
PPS format (self-contained PowerPoint show)
PPS format (self-contained PowerPoint show)

... Two methods: ...
miR-409-3p - Clinical Cancer Research
miR-409-3p - Clinical Cancer Research

... Sajni Josson1, Murali Gururajan1, Peizhen Hu1, Chen Shao1, Gina Chia-Yi Chu1, Haiyen E. Zhau1, Chunyan Liu1, ...
Summer 2005 Joseph Leach, M.D., medical director, St. Francis Cancer Center, with
Summer 2005 Joseph Leach, M.D., medical director, St. Francis Cancer Center, with

Letter to Nature Medicine Version 1
Letter to Nature Medicine Version 1

... Prostate cancer (CaP) is diagnosed in close to 900,000 men annually worldwide, with 250,000 CaP deaths each year.1 The majority of cases are localized cancers (T1-T4N0M0), which are stratified into low-, intermediate- and high-risk groups based on their relative prostate-cancer specific mortality (P ...
The World Cancer Declaration
The World Cancer Declaration

... • Promote the development and use of cancer treatment guidelines that are relevant to local needs and resources. Ensure that sufficient treatment, rehabilitation and palliative care facilities and well-trained staff are available to meet the physical, social and emotional needs of patients with can ...
Advanced prostate cancer
Advanced prostate cancer

... What is advanced prostate cancer? Advanced prostate cancer is cancer that has spread from the prostate to other parts of the body. It develops when prostate cancer cells move through the blood stream or lymphatic system. The lymphatic system is part of the body’s immune system. You might hear cancer ...
661 kB - Cancer Council NSW
661 kB - Cancer Council NSW

... There is no national screening program for the early detection of prostate cancer. Doctors have different opinions about whether all men without symptoms of prostate cancer should be tested. There is concern that testing healthy men will cause unnecessary harm and lead to treatments that may not off ...
PPT Version - OMICS International
PPT Version - OMICS International

... Study of transcription factors NF-kappaB and STAT3 signaling pathway, death receptor pathway, extrinsic and intrinsic pathway of apoptosis, anticancer properties of natural compounds in both in vitro and nude mouse models, study of cell cycle by flow cytometry, study of oxidative stress in animal mo ...
last - News | National Cancer Registry Ireland
last - News | National Cancer Registry Ireland

... The latest report from the National Cancer Registry released today shows some interesting trends in cancer incidence in Ireland. The number of newly diagnosed cancers is increasing by 6-7% annually and this is likely to double in the next 20...Read more ...
Insights into Chemoresistance of Prostate Cancer
Insights into Chemoresistance of Prostate Cancer

... Prostate cancer (PCa) remains the most prevalent malignancy among males in the western world. Though hormonal therapies through chemical or surgical castration have been proposed many years ago, heretofore, such mainstay for the treatment on advanced PCa has not fundamentally changed. These therapeu ...
SG2006coloncancer - Jacobi Medical Center
SG2006coloncancer - Jacobi Medical Center

... Adenoma (any) ...
The worldwide burden of cancer
The worldwide burden of cancer

CancerVive_Media_Release_2013_(3)-228
CancerVive_Media_Release_2013_(3)-228

of Androgen Receptor Activity
of Androgen Receptor Activity

... are required for AR activity. Two examples are SRC1–3 and CREB-binding protein (CBP), which interact with the AR NTD, and their levels of expression are increased in CRPC. EPI-001 inhibits interaction between CBP and AR in response to both androgen and in the absence of androgen, by IL-6 (22). CBP i ...
Clin Cancer Res-2014-Bolton-35-43 - TARA
Clin Cancer Res-2014-Bolton-35-43 - TARA

... Responsible for approximately 30,000 deaths annually in the United States and 258,000 deaths worldwide, prostate cancer is the most common noncutaneous malignancy and third leading cause of cancer-related deaths in men in the Western world (4). This review provides a snapshot of the variety of roles ...
Prostate Depiction at Endorectal MR Spectroscopic Imaging
Prostate Depiction at Endorectal MR Spectroscopic Imaging

... Approximately 8% of American men will receive a diagnosis of prostate cancer during their lifetime, and 20% of these men will die of the disease (1). Despite this sizeable mortality rate, many cases of prostate cancer are subclinical, and microscopic foci of incidental prostate cancer can be detecte ...
Nutrition and Disease
Nutrition and Disease

... athymic nude mice. This model allows investigation of organspecific chemopreventive effects through monitoring of in situ tumor growth by transrectal ultrasonography and simultaneous recording of plasma PSA levels (35–37). Because the uptake of lycopene and a-tocopherol in the prostate is likely ins ...
What is Colorectal Cancer?
What is Colorectal Cancer?

... • If found early through regular screening, the success rate for treatment is greater than 90% • If found at a later stage when there are symptoms, only about 10% of people survive (to 5 years) • Screening can also prevent colorectal cancer by removing pre-cancerous polyps ...
Chemotherapy for Castration Resistant Metastatic Prostate Cancer
Chemotherapy for Castration Resistant Metastatic Prostate Cancer

... a long and often slow process and varies widely individually. It has been postulated based on tissue samples obtained from autopsies that prostate cancer cells are present in a very high proportion of males over the age of 70. (Sakr et al. 1996, Powell et al. 2010, Stamatiou et al. 2006) While the d ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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