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The genomic complexity of primary human prostate cancer Please share
The genomic complexity of primary human prostate cancer Please share

... we present the complete sequence of seven primary prostate cancers and their paired normal counterparts. Several tumors contained complex chains of balanced rearrangements that occurred within or adjacent to known cancer genes. Rearrangement breakpoints were enriched near open chromatin, androgen re ...
Prostate Cancer News In this issue Queensland Guest Editorial,
Prostate Cancer News In this issue Queensland Guest Editorial,

Mammography screening does not work and
Mammography screening does not work and

Inside the world`s largest hereditary cancer biobank
Inside the world`s largest hereditary cancer biobank

... public healthcare worldwide. Many forms of cancer have genetically inherited origins. Scientists have discovered a number of genetic mutations that can contribute to an individual’s risk of developing certain cancers, such as breast, ovarian, colorectal, and prostate cancers, as well as some other, ...
Therapeutic value of lymph node dissection at radical prostatectomy
Therapeutic value of lymph node dissection at radical prostatectomy

... What’s known on the subject? and What does the study add? Pelvic lymph node dissection (PLND) at radical prostatectomy is typically used to determine the loco-regional extent of cancer, and to help determine the risk of recurrence and need for adjuvant therapy. Recent improvements in imaging and ris ...
Luteinizing hormone-releasing hormone analogues and hormone
Luteinizing hormone-releasing hormone analogues and hormone

... administered once per month or even once every 3–6 months, makes the treatment of prostate cancer more convenient, practical and effective [1,5,9,10]. These regimens also ensure better patient compliance than is obtained with daily injections. Side-effects of chronic administration of LHRH agonists ...
PROSTATE CANCER CARE IMPROVING
PROSTATE CANCER CARE IMPROVING

Overexpression, Amplification, and Androgen Regulation of TPD52
Overexpression, Amplification, and Androgen Regulation of TPD52

... (i.e., no hormonal or radiation therapy) for clinically localized prostate cancer between January 1995 and December 2001. Tumors were staged using the tumor-node-metastasis (TNM) system (23) and graded according to the system originally described by Gleason (24, 25). The snap-frozen samples used for ...
Breast Cancer Facts
Breast Cancer Facts

...  The most common risk factors for breast cancer are being female and getting older.  With respect to age, race, religion and socioeconomic status, breast cancer knows no boundaries.  Breast cancer affects everyone, not just the person diagnosed. Co-survivors, including family, friends and co-work ...
Hormone therapy drug: degarelix
Hormone therapy drug: degarelix

... a short course of anti-androgen tablets to help stop this surge. Degarelix doesn’t cause a temporary surge in testosterone, so you won’t need to take anti-androgen tablets. Instead, your testosterone levels will start to drop straight away. This means that if you have any symptoms of advanced prosta ...
Oral Cancer Awareness Month PR 24.03.15
Oral Cancer Awareness Month PR 24.03.15

... in the UK to be aware of the early signs of mouth cancer and to visit their dentist regularly. Mouth cancer can strike anyone at anytime. Worldwide the disease affects 650,000 people a year and it is the 6th most common type of cancer. In the UK there are more than 8000 people diagnosed with mouth c ...
PC Detect - Panacea Global, Inc
PC Detect - Panacea Global, Inc

New Cancers After BCG
New Cancers After BCG

... • Grade 1: 16,884 (18.5%) • Grade 2: 32,049 (35.1%) • Grade 3: 24,065 (26.4%) • Grade 4: 6,612 (7.2%) • Unknown: 11,635 (12.8%) • Of known grades: 61.5% low grade (1-2), 38.5% high grade (3-4) Onc. 19:94-100, 2001) ...
Improved blood tests for cancer screening: general or specific? Open Access
Improved blood tests for cancer screening: general or specific? Open Access

London Cancer: Prostate Cancer Stratified Follow–Up
London Cancer: Prostate Cancer Stratified Follow–Up

... assessment, information provision and care planning. The rationale for this shift is that there is no evidence that traditional follow-up, consisting of regular appointments in secondary care, provides the most effective care or best means to detect disease recurrence. In addition, longer life expec ...
Recommendations for screening and surveillance for specific cancers
Recommendations for screening and surveillance for specific cancers

Cancer in Latin America and the Caribbean
Cancer in Latin America and the Caribbean

... other compounds are well-documented causes of cancer. In the Americas, lung cancer caused by workplace exposure is estimated to be 5% - 8%. Deaths from malignant mesothelioma, in the region caused by workplace exposure is estimated to be 700- 2,200. In Brazil, up to 5% of the labor force in the form ...
this PDF file - Co-Action Publishing JOURNALS
this PDF file - Co-Action Publishing JOURNALS

... reviewed and only 8 men had a screening PSA test prior to symptoms leading to a prostate cancer diagnosis (personal communication, K. Koller). It is conceivable that the low rate of prostate cancer is due to lack of detection. However, as shown in Figure 3, the proportion of patients diagnosed with ...
Metabolic Imaging in Prostate Cancer: Where We Are
Metabolic Imaging in Prostate Cancer: Where We Are

... can overlap, determining the low specificity of these tracers for primary PCa detection (20). In a systematic review and metaanalysis of 11C-acetate PET/CT in PCa, pooled sensitivity and pooled specificity for evaluation of primary tumor were 75.1% (95% CI: 69.8–79.8%) and 75.8% (95% CI: 72.4–78.9%) ...
Standard PDF - Wiley Online Library
Standard PDF - Wiley Online Library

... shown in Table 1 [12,15,17]. The National Cancer Institute (NCI) has published annual cost data for prostate cancer using the most recent cancer incidence, survival and cost ...
Cancer screening has never been shown to “save lives”
Cancer screening has never been shown to “save lives”

... with false positive results, overdiagnosis of non-harmful cancers, and detection of incidental findings. For example, prostate specific antigen (PSA) testing yields numerous false positive results, which contribute to over one million prostate biopsies a year.12 Prostate biopsies are associated with ...
pelvic mri course
pelvic mri course

... credit commensurate with the extent of their participation in the activity. The AMA has determined that physicians not licensed in the United States but who participate in this CME activity are eligible for 19.75 AMA PRA Category 1 Credits™. EVALUATION ...
World cancer day 2013
World cancer day 2013

... UICC, Geneva, American Cancer Society, Atlanta, Ministry of Health and Family Welfare, New Delhi and Deccan Hearld, New Delhi Bureau for their materials used to prepare this presentation in public interest. Dr. Rakesh Gupta ...
American Cancer Society
American Cancer Society

... to study a protein that is involved in promoting the spread of cancer cells through the human body, particularly breast, colorectal, and lung cancers. Dr. Copie’s research focuses on how to stop these cancers from metastasizing. b. Messengers for Health on the Apsaalooke Reservation – Dr. Suzanne Ch ...
A New Era in Cancer Care - Augusta University Health
A New Era in Cancer Care - Augusta University Health

... and Gynecology and Chief of the Section of Gynecologic Oncology. His clinical and research interests include ovarian cancer, cervix cancer and chemotherapy trials. Dr. Anand P. Jillella, Hematology/Oncology. Dr. Jillella is Professor of Medicine, and Chief of the Division of Hematology/Oncology and ...
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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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