product monograph isoptin sr
... Because of the drug’s negative inotropic effect, ISOPTIN® SR should not be used in patients with poorly compensated congestive heart failure. Heart failure patients with ejection fraction higher than 40% should be treated with adequate doses of digoxin and/or diuretics before starting ISOPTIN® SR tr ...
... Because of the drug’s negative inotropic effect, ISOPTIN® SR should not be used in patients with poorly compensated congestive heart failure. Heart failure patients with ejection fraction higher than 40% should be treated with adequate doses of digoxin and/or diuretics before starting ISOPTIN® SR tr ...
Stability considerations in liquid dosage forms extemporaneously
... milligrams per kilogram of body weight and most children under six years of age cannot swallow tablets (15, 16). A survey (14) into the informational needs of hospital compounding pharmacists providing pharmaceutical care to paediatric patients at 57 sites in the USA and Canada listed 76 extemporane ...
... milligrams per kilogram of body weight and most children under six years of age cannot swallow tablets (15, 16). A survey (14) into the informational needs of hospital compounding pharmacists providing pharmaceutical care to paediatric patients at 57 sites in the USA and Canada listed 76 extemporane ...
Combinations of antifungal agents in therapy–what value are they?
... or synergy in vitro between amphotericin B and miconazole, fluconazole or itraconazole against clinical isolates of Pseudallescheria boydii. Antagonism was not observed.50 Azole agents plus flucytosine. Effects in vitro of an azole agent and flucytosine combinations have been less frequently investi ...
... or synergy in vitro between amphotericin B and miconazole, fluconazole or itraconazole against clinical isolates of Pseudallescheria boydii. Antagonism was not observed.50 Azole agents plus flucytosine. Effects in vitro of an azole agent and flucytosine combinations have been less frequently investi ...
ASPIRIN
... and this should be inserted no more than 2.5cm in children and 4-5cm in adults. (All tubes have an insertion marker on nozzle). ...
... and this should be inserted no more than 2.5cm in children and 4-5cm in adults. (All tubes have an insertion marker on nozzle). ...
P R E S C R I B I N G I N F O R M A T I O N
... conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The prescriber should be aware that the adverse reaction incidence figures in the following tab ...
... conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The prescriber should be aware that the adverse reaction incidence figures in the following tab ...
Update on the Management of Onychomycosis: Highlights of the
... with nail dermatophytosis in the United Kingdom suggested a prevalence of 2.7% in the general population [2]. In the previous century, onychomycosis was rare and generally occurred in the fingernails of persons with tinea capitis and in their care givers. Both onychomycosis and tinea pedis are now c ...
... with nail dermatophytosis in the United Kingdom suggested a prevalence of 2.7% in the general population [2]. In the previous century, onychomycosis was rare and generally occurred in the fingernails of persons with tinea capitis and in their care givers. Both onychomycosis and tinea pedis are now c ...
London 2012 Paralympic Games Pharmacy Guide
... Exchange, LOCOG’s secure extranet for NPCs, at https://theexchange.london2012.com. In most situations, UK medicines legislation does not impose restrictions on the import of medicines for personal use. However, for the purposes of team preparations leading up to and during the Olympic and Paralympic ...
... Exchange, LOCOG’s secure extranet for NPCs, at https://theexchange.london2012.com. In most situations, UK medicines legislation does not impose restrictions on the import of medicines for personal use. However, for the purposes of team preparations leading up to and during the Olympic and Paralympic ...
Meta-analysis of the Effect of CYP3A4*18B Gene Polymorphism on
... dose ratio. There were two studies of 7 days or less post transplantation, two studies of 14 days post transplant, three studies of 1 month post transplant, one study of two months post transplant, 3 studies of three months post transplant and one study of six months post transplant. Because the num ...
... dose ratio. There were two studies of 7 days or less post transplantation, two studies of 14 days post transplant, three studies of 1 month post transplant, one study of two months post transplant, 3 studies of three months post transplant and one study of six months post transplant. Because the num ...
... postoperative opioid use, opioid-related side effects (e.g., nausea and vomiting) and pain are uncertain, as randomized controlled trials on this topic have reported disparate results. The objective of this systematic review is to determine if perioperative magnesium reduces opioid use, opioid-relat ...
ELECTRICALLY ASSISTED TRANSDERMAL DELIVERY OF ESCIN
... Preparation of the electric circuit used in the in vitro permeation studies An electric circuit was custom designed 26 using 220 volts input source to deliver direct current. A rheostat was used to adjust the current intensity at the desired predetermined values. A potentiometer and transistor were ...
... Preparation of the electric circuit used in the in vitro permeation studies An electric circuit was custom designed 26 using 220 volts input source to deliver direct current. A rheostat was used to adjust the current intensity at the desired predetermined values. A potentiometer and transistor were ...
Position Paper: Gastric Lavage
... ibuprofen 400 mg, and citalopram 20 mg simultaneously, and then 30 minutes later received water 200 ml (control group), charcoal 25 gm in 200 ml water, or lavage followed by charcoal. The combination of gastric lavage and activated charcoal reduced the AUC (0,10) of diazepam by 27% (p < 0.05), of ib ...
... ibuprofen 400 mg, and citalopram 20 mg simultaneously, and then 30 minutes later received water 200 ml (control group), charcoal 25 gm in 200 ml water, or lavage followed by charcoal. The combination of gastric lavage and activated charcoal reduced the AUC (0,10) of diazepam by 27% (p < 0.05), of ib ...
Drug-induced oral lichenoid reactions. A literature review
... The terms oral lichenoid reactions or oral lichenoid lesions refer to lesions histologically and clinically similar to oral lichen planus, though with the particularity that in these cases the underlying cause is identifiable. In addition, these lesions are described according to the causal factor i ...
... The terms oral lichenoid reactions or oral lichenoid lesions refer to lesions histologically and clinically similar to oral lichen planus, though with the particularity that in these cases the underlying cause is identifiable. In addition, these lesions are described according to the causal factor i ...
Allopurinol Orion 300 mg tablet ENG SmPC
... reported. If such reactions do occur, it may be at any time during treatment, Allopurinol Orion should be withdrawn immediately and permanently. Rechallenge should not be undertaken in patients with hypersensitivity syndrome and SJS/TEN. Corticosteroids may be beneficial in overcoming hypersensitivi ...
... reported. If such reactions do occur, it may be at any time during treatment, Allopurinol Orion should be withdrawn immediately and permanently. Rechallenge should not be undertaken in patients with hypersensitivity syndrome and SJS/TEN. Corticosteroids may be beneficial in overcoming hypersensitivi ...
poly(lactic-co-glycolic acid) based drug delivery devices
... several advantages over the conventional devices. One of the advantage is the extended release rates of drugs up to days, weeks or months. Other reasons for the widespread use of PLGA are its biodegradability, its biocompatibility, and the fact that PLGA has been approved by FDA (Food and Drug Admin ...
... several advantages over the conventional devices. One of the advantage is the extended release rates of drugs up to days, weeks or months. Other reasons for the widespread use of PLGA are its biodegradability, its biocompatibility, and the fact that PLGA has been approved by FDA (Food and Drug Admin ...
MtM essentials for asthma management: part 2
... be challenging because of differences in patients’ and providers’ perceptions of control. A 2006 telephonic survey was designed to assess both asthma control among adult patients and knowledge and practices among providers actively involved in asthma management.4 For the purposes of this study, cont ...
... be challenging because of differences in patients’ and providers’ perceptions of control. A 2006 telephonic survey was designed to assess both asthma control among adult patients and knowledge and practices among providers actively involved in asthma management.4 For the purposes of this study, cont ...
Gastrointestinal Disorders: Nausea in Adults
... their effectiveness, with the exception of serotonin (5HT3) antagonists for CINV (see Cancer Chemotherapy Toxicity: Chemotherapyinduced Nausea and Vomiting) and PONV. When selecting a drug, consider if the nausea is acute or chronic, review concurrent medications and attempt to identify the underl ...
... their effectiveness, with the exception of serotonin (5HT3) antagonists for CINV (see Cancer Chemotherapy Toxicity: Chemotherapyinduced Nausea and Vomiting) and PONV. When selecting a drug, consider if the nausea is acute or chronic, review concurrent medications and attempt to identify the underl ...
Relanio inhalation 50_250 microgram 50_500 microgram per dose
... therefore, that the patient is reviewed regularly and the dose of inhaled corticosteroid is reduced to the lowest dose at which effective control of asthma is maintained. Prolonged treatment of patients with high doses of inhaled corticosteroids may result in adrenal suppression and acute adrenal cr ...
... therefore, that the patient is reviewed regularly and the dose of inhaled corticosteroid is reduced to the lowest dose at which effective control of asthma is maintained. Prolonged treatment of patients with high doses of inhaled corticosteroids may result in adrenal suppression and acute adrenal cr ...
Identification of the date-rape drug GHB and its precursor GBL by
... identify GHB and GBL in solution using Raman spectroscopy. Figure 4 shows the Raman spectra of GHB in water at a range of the concentrations recorded on the Delta Nu Inspector Raman instrument. The spectra of GHB in water shows two bands, one at 946 cm−1 assigned to C-C stretching and the other at 1 ...
... identify GHB and GBL in solution using Raman spectroscopy. Figure 4 shows the Raman spectra of GHB in water at a range of the concentrations recorded on the Delta Nu Inspector Raman instrument. The spectra of GHB in water shows two bands, one at 946 cm−1 assigned to C-C stretching and the other at 1 ...
Clinical Pharmacokinetics Of
... of therapy yield relatively little information about the eventual steady-state concentrations. For this reason, routine plasma Phenobarbital concentrations should be monitored two to three weeks after the initiation or a change in the Phenobarbital regimen. Plasma samples obtained before this time s ...
... of therapy yield relatively little information about the eventual steady-state concentrations. For this reason, routine plasma Phenobarbital concentrations should be monitored two to three weeks after the initiation or a change in the Phenobarbital regimen. Plasma samples obtained before this time s ...
Fonat - Medicines.org.au
... discontinuation of alendronate despite the long retention of alendronate in the skeleton. Long-term treatment of osteoporosis with alendronate 10 mg/day (for up to five years) reduced urinary excretion of markers of bone resorption, deoxypyridinoline and cross-linked N-telopeptides of type I collage ...
... discontinuation of alendronate despite the long retention of alendronate in the skeleton. Long-term treatment of osteoporosis with alendronate 10 mg/day (for up to five years) reduced urinary excretion of markers of bone resorption, deoxypyridinoline and cross-linked N-telopeptides of type I collage ...
Amphetamine-Type Stimulants: A Global Review, 1996
... known about their consumption indeed suggests that they are used, or abused, precisely because they combine these effects. Further compounding the analytical problem is the fact that they do not have any officially recognized therapeutic value. Yet the extent of their illicit consumption appears to ...
... known about their consumption indeed suggests that they are used, or abused, precisely because they combine these effects. Further compounding the analytical problem is the fact that they do not have any officially recognized therapeutic value. Yet the extent of their illicit consumption appears to ...
LIPIDIL MICRO PM
... up to >3 times the upper limit of normal occurred in 2.9% (14/477) of patients taking fenofibrate versus 0.5% (2/386) of those treated with placebo. In the DAIS study (3 years duration), increases up to 3 times the upper limit of normal occurred in 1.9% (4/207) of patients taking fenofibrate versus ...
... up to >3 times the upper limit of normal occurred in 2.9% (14/477) of patients taking fenofibrate versus 0.5% (2/386) of those treated with placebo. In the DAIS study (3 years duration), increases up to 3 times the upper limit of normal occurred in 1.9% (4/207) of patients taking fenofibrate versus ...
article
... products. All questions in section 2 had the following answers: always, often, sometimes, rarely and never. Section number 3 included 5 questions about attitude of community pharmacists toward herbal products: do you agree that herbal products have beneficial effects; do you agree that herbal produc ...
... products. All questions in section 2 had the following answers: always, often, sometimes, rarely and never. Section number 3 included 5 questions about attitude of community pharmacists toward herbal products: do you agree that herbal products have beneficial effects; do you agree that herbal produc ...
Onychomycosis: Current Trends in Diagnosis and Treatment
... Pulse dosing: 200 mg orally two times per day for one week per month, for two months (fingernails) or three months (toenails) ...
... Pulse dosing: 200 mg orally two times per day for one week per month, for two months (fingernails) or three months (toenails) ...
Bad Pharma
.JPG?width=300)
Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.