Rennie Dual Action Tablets
... Prolonged use of high doses may result in undesirable side-effects such as hypercalcaemia, magnesaemia and the milk alkali syndrome, particularly in patients suffering from renal insufficiency. The product should not be taken with large amounts of milk or dairy products. Prolonged use increases the ...
... Prolonged use of high doses may result in undesirable side-effects such as hypercalcaemia, magnesaemia and the milk alkali syndrome, particularly in patients suffering from renal insufficiency. The product should not be taken with large amounts of milk or dairy products. Prolonged use increases the ...
Terbutaline Sulfate Tablets
... after administration of terbutaline sulfate to pregnant women. In the mother, these adverse reactions include increased heart rate, transient hyperglycemia, hypokalemia, cardiac arrhythmias, pulmonary edema and myocardial ischemia. Increased fetal heart rate and neonatal hypoglycemia may occur as a ...
... after administration of terbutaline sulfate to pregnant women. In the mother, these adverse reactions include increased heart rate, transient hyperglycemia, hypokalemia, cardiac arrhythmias, pulmonary edema and myocardial ischemia. Increased fetal heart rate and neonatal hypoglycemia may occur as a ...
Effect of compression force, humidity and disintegrant concentration
... with the surface of the die. The open bottom of the die was sealed with a stainless steel pellet. The die was then firmly pushed down in a stainless steel “saucer”, which fitted tightly around the die. Tablet Storage The International Conference on Harmonization (ICH) is developing stability standar ...
... with the surface of the die. The open bottom of the die was sealed with a stainless steel pellet. The die was then firmly pushed down in a stainless steel “saucer”, which fitted tightly around the die. Tablet Storage The International Conference on Harmonization (ICH) is developing stability standar ...
Cyclobenzaprine extended release for acute low back and neck pain
... more effective than placebo in the treatment of muscle spasm, and is as effective as 10 mg t.i.d. with fewer AEs [28] . Of the 14 studies on the use of cyclobenzaprine IR in low back and neck pain that were included in a meta-analysis [17] , ten looked for and reported a global improvement in symp ...
... more effective than placebo in the treatment of muscle spasm, and is as effective as 10 mg t.i.d. with fewer AEs [28] . Of the 14 studies on the use of cyclobenzaprine IR in low back and neck pain that were included in a meta-analysis [17] , ten looked for and reported a global improvement in symp ...
Randomized, Placebo-Controlled Trial of Exposure and Ritual
... the most efficacious medication for OCD (16, 17). Although exposure and ritual prevention and SRIs are each efficacious treatments, some patients do not benefit from these interventions and most remain at least somewhat symptomatic. An important question concerns the relative and combined efficacy o ...
... the most efficacious medication for OCD (16, 17). Although exposure and ritual prevention and SRIs are each efficacious treatments, some patients do not benefit from these interventions and most remain at least somewhat symptomatic. An important question concerns the relative and combined efficacy o ...
Product Monograph
... coupled with self-harm and harm to others. The agitation-type events include: akathisia, agitation, emotional lability, hostility, aggression, depersonalization. In some cases, the events occurred within several weeks of starting treatment. Rigorous clinical monitoring for suicidal ideation or other ...
... coupled with self-harm and harm to others. The agitation-type events include: akathisia, agitation, emotional lability, hostility, aggression, depersonalization. In some cases, the events occurred within several weeks of starting treatment. Rigorous clinical monitoring for suicidal ideation or other ...
Slide Set
... EMEND®: Overall Adverse Experiences • Most adverse experiences were mild to moderate in intensity • Drug-related adverse experiences: Cycle 1 – Approximately 17% of patients treated with EMEND with control regimens* reported clinical adverse experiences compared with approximately 13% of patients t ...
... EMEND®: Overall Adverse Experiences • Most adverse experiences were mild to moderate in intensity • Drug-related adverse experiences: Cycle 1 – Approximately 17% of patients treated with EMEND with control regimens* reported clinical adverse experiences compared with approximately 13% of patients t ...
Lamictal - GSK Source
... (1) Taking Estrogen-Containing Oral Contraceptives: In women not taking carbamazepine, phenytoin, phenobarbital, primidone, or other drugs such as rifampin and the protease inhibitors lopinavir/ritonavir and atazanavir/ritonavir that induce lamotrigine glucuronidation [see Drug Interactions (7), Cli ...
... (1) Taking Estrogen-Containing Oral Contraceptives: In women not taking carbamazepine, phenytoin, phenobarbital, primidone, or other drugs such as rifampin and the protease inhibitors lopinavir/ritonavir and atazanavir/ritonavir that induce lamotrigine glucuronidation [see Drug Interactions (7), Cli ...
Methamphetamine Action Plan
... and enhanced mood. The effects of methamphetamine are dose dependent, however, the following effects will occur at greater or lesser levels; euphoria, increased activity and energy levels, dis-inhibition, sense of well-being, increased confidence (often termed ‘bullet-proof’), decreased appetite and ...
... and enhanced mood. The effects of methamphetamine are dose dependent, however, the following effects will occur at greater or lesser levels; euphoria, increased activity and energy levels, dis-inhibition, sense of well-being, increased confidence (often termed ‘bullet-proof’), decreased appetite and ...
Chapter 15. Diuretic Agents
... Metabolic alkalosis is generally treated by correction of abnormalities in total body K+, intravascular volume, or mineralocorticoid levels. However, when the alkalosis is due to excessive use of diuretics in patients with severe heart failure, saline administration may be contraindicated. In these ...
... Metabolic alkalosis is generally treated by correction of abnormalities in total body K+, intravascular volume, or mineralocorticoid levels. However, when the alkalosis is due to excessive use of diuretics in patients with severe heart failure, saline administration may be contraindicated. In these ...
Adverse events associated with dietary supplements - Direct-MS
... (P E McKinney, MD); Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD (W Klein-Schwartz PharmD); National ...
... (P E McKinney, MD); Maryland Poison Center, University of Maryland School of Pharmacy, Baltimore, MD (W Klein-Schwartz PharmD); National ...
JIPBS Simple UV spectrophotometric assay of Furosemide Original Article
... is used that is in decompensate heart failure, when we require rapid diuretic action and intestinal absorption may be delayed because of gastrointestinal oedema Thus, time to peak, lag time and peak of serum concentration may differ in compensated when compared with decompensate patients after the o ...
... is used that is in decompensate heart failure, when we require rapid diuretic action and intestinal absorption may be delayed because of gastrointestinal oedema Thus, time to peak, lag time and peak of serum concentration may differ in compensated when compared with decompensate patients after the o ...
20110503_Manuscript - international journal of advances in
... Atrial fibrillation (AF) causes about 75,000 cases of ischemic stroke per year in the United States. There are several risk factors for stroke including age greater than 75 years, hypertension, diabetes and smoking[37]. AF causes stroke by thrombus formation in the left atrium with embolism to the b ...
... Atrial fibrillation (AF) causes about 75,000 cases of ischemic stroke per year in the United States. There are several risk factors for stroke including age greater than 75 years, hypertension, diabetes and smoking[37]. AF causes stroke by thrombus formation in the left atrium with embolism to the b ...
ACTELION`S NEW DUAL OREXIN RECEPTOR ANTAGONIST
... Study 1: ~300 adult insomnia patients – treatment duration 4 weeks Study 2: ~50 elderly insomnia patients Adult study will also include an active-reference arm with zolpidem Actelion’s New DORA is an investigational drug in development and not approved or marketed in any country ...
... Study 1: ~300 adult insomnia patients – treatment duration 4 weeks Study 2: ~50 elderly insomnia patients Adult study will also include an active-reference arm with zolpidem Actelion’s New DORA is an investigational drug in development and not approved or marketed in any country ...
Presentation
... simultaneously to reverse residual non-depolarising (competitive) neuromuscular block. Numerous clinical studies, which demonstrate this to be a safe and effective combination, have been published. Over 90% of the Glycopyrronium Bromide disappears from serum within 5 minutes following intravenous ad ...
... simultaneously to reverse residual non-depolarising (competitive) neuromuscular block. Numerous clinical studies, which demonstrate this to be a safe and effective combination, have been published. Over 90% of the Glycopyrronium Bromide disappears from serum within 5 minutes following intravenous ad ...
Current status and future potential.
... As it relates to the potential for future medicinal applications, we suggest that there exists no compelling data to begin to suggest that plant marijuana for medicinal applications provides an advantage over individual cannabinoids or other existing medicine. For the most part, positive or negative ...
... As it relates to the potential for future medicinal applications, we suggest that there exists no compelling data to begin to suggest that plant marijuana for medicinal applications provides an advantage over individual cannabinoids or other existing medicine. For the most part, positive or negative ...
SALT SOLID DISPERSIONS
... It is difficult to express in words the deep sense of gratitude that I have for my respected advisor, Dr. Tamara Minko. Her scientific curiosity, assertiveness at every critical step, generous encouragement and patience has made this thesis possible. She has become a role model for me not only as sh ...
... It is difficult to express in words the deep sense of gratitude that I have for my respected advisor, Dr. Tamara Minko. Her scientific curiosity, assertiveness at every critical step, generous encouragement and patience has made this thesis possible. She has become a role model for me not only as sh ...
PerspectiVe
... as surface plasmon resonance (SPR), protein-ligand NMR, or even X-ray crystallography is much more achievable compared with assembling and screening a large library in a bioassay. In fact, some of the pioneering work using X-ray crystallography for fragment screening was done at the University of Gr ...
... as surface plasmon resonance (SPR), protein-ligand NMR, or even X-ray crystallography is much more achievable compared with assembling and screening a large library in a bioassay. In fact, some of the pioneering work using X-ray crystallography for fragment screening was done at the University of Gr ...
Intranasal (IN) Medication Administration MBED Clinical Practice
... to reduce anxiety, pain, fear, and trauma, so we should not be causing these things when we administer them! 3) IN medications can cause a mild burning sensation for up to 30 seconds (usually with midazolam and it lasts 3045 seconds) so forewarn the parents that the child will initially cry (but not ...
... to reduce anxiety, pain, fear, and trauma, so we should not be causing these things when we administer them! 3) IN medications can cause a mild burning sensation for up to 30 seconds (usually with midazolam and it lasts 3045 seconds) so forewarn the parents that the child will initially cry (but not ...
Filling two-piece hard gelatin capsules with liquids
... have attracted substantial interest in the pharmaceutical industry over the last decade. Today’s challenges in product development due to the poor aqueous solubility and high potency of the new molecular entities are being addressed by several development groups that are focused on liquid or semi-so ...
... have attracted substantial interest in the pharmaceutical industry over the last decade. Today’s challenges in product development due to the poor aqueous solubility and high potency of the new molecular entities are being addressed by several development groups that are focused on liquid or semi-so ...
STALEVO (carbidopa, levodopa and entacapone)
... gamble, increased sexual urges, intense urges to spend money uncontrollably, and other intense urges. Patients may be unable to control these urges while taking one or more of the medications generally used for the treatment of Parkinson’s disease and which increase central dopaminergic tone, includ ...
... gamble, increased sexual urges, intense urges to spend money uncontrollably, and other intense urges. Patients may be unable to control these urges while taking one or more of the medications generally used for the treatment of Parkinson’s disease and which increase central dopaminergic tone, includ ...
Form 10-Q
... implied by these forward-looking statements. Factors that may cause actual results to differ materially from current expectations include, among other things, those listed under Part II, Item 1A. Risk Factors and elsewhere in this Quarterly Report on Form 10-Q. Given these uncertainties, you should ...
... implied by these forward-looking statements. Factors that may cause actual results to differ materially from current expectations include, among other things, those listed under Part II, Item 1A. Risk Factors and elsewhere in this Quarterly Report on Form 10-Q. Given these uncertainties, you should ...
Bad Pharma
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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.