Life`s unity and flexibility: the ecological link
... electron acceptors can oxidize a greater variety of substances, e.g., aerobic lithotrophs; thus, certain nitrate reducers (anaerobic respiration) can oxidize sulfide, ferrous iron, methane, nitrite, and ammonia. At life’s origin, certain biosynthetic processes probably occurred spontaneously, either ...
... electron acceptors can oxidize a greater variety of substances, e.g., aerobic lithotrophs; thus, certain nitrate reducers (anaerobic respiration) can oxidize sulfide, ferrous iron, methane, nitrite, and ammonia. At life’s origin, certain biosynthetic processes probably occurred spontaneously, either ...
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for anti-viral therapy.
... Viruses rely on the metabolic network of their cellular hosts to provide energy and building blocks for viral replication. We developed a flux measurement approach based on liquid chromatography–tandem mass spectrometry to quantify changes in metabolic activity induced by human cytomegalovirus (HCMV ...
... Viruses rely on the metabolic network of their cellular hosts to provide energy and building blocks for viral replication. We developed a flux measurement approach based on liquid chromatography–tandem mass spectrometry to quantify changes in metabolic activity induced by human cytomegalovirus (HCMV ...
Metabolism of cardiac muscles
... The glucose-fatty acid (Randle) cycle • The Randle cycle describes the reciprocal relationship between fatty acid and glucose metabolism. • The increased generation of acetyl CoA derived from fatty acid-oxidation decreases glucose (pyruvate) oxidation. • The increased generation of acetyl CoA deriv ...
... The glucose-fatty acid (Randle) cycle • The Randle cycle describes the reciprocal relationship between fatty acid and glucose metabolism. • The increased generation of acetyl CoA derived from fatty acid-oxidation decreases glucose (pyruvate) oxidation. • The increased generation of acetyl CoA deriv ...
Tenofovir - NHS Grampian
... increases in serum ALT. After initiating antiviral therapy, serum ALT may increase in some patients as serum HBV DNA levels decline. In patients with compensated liver disease, these increases in serum ALT are generally not accompanied by an increase in serum bilirubin concentrations or hepatic deco ...
... increases in serum ALT. After initiating antiviral therapy, serum ALT may increase in some patients as serum HBV DNA levels decline. In patients with compensated liver disease, these increases in serum ALT are generally not accompanied by an increase in serum bilirubin concentrations or hepatic deco ...
Pathways - PharmaStreet
... • The pathways for generally modifying and synthesizing carbohydrates, proteins, fats, and nucleic acids are found to be essentially the same in all organisms, apart from minor variations. • These processes are collectively described as primary metabolism, with the compounds involved in the pathway ...
... • The pathways for generally modifying and synthesizing carbohydrates, proteins, fats, and nucleic acids are found to be essentially the same in all organisms, apart from minor variations. • These processes are collectively described as primary metabolism, with the compounds involved in the pathway ...
Muscle
... Regulated in Cells? • AMP-activated protein kinase (AMPK) is the cellular energy sensor • Metabolic inputs to this sensor determine whether its output (protein kinase activity) takes place • The competition between ATP (inactivate) and AMP (activate) for binding to the AMPK allosteric sites determin ...
... Regulated in Cells? • AMP-activated protein kinase (AMPK) is the cellular energy sensor • Metabolic inputs to this sensor determine whether its output (protein kinase activity) takes place • The competition between ATP (inactivate) and AMP (activate) for binding to the AMPK allosteric sites determin ...
Genome-wide identification of mononuclear cell DNA methylation
... plasma OCM metabolites, s-adenosylmethionine (SAM), s-adenosylhomocysteine (SAH) and Hcy, and diet. Associations between OCM metabolites and MetS features were also investigated. In an 8-week human cross-over intervention study we investigated whether a diet rich in whole grain compared to a diet ri ...
... plasma OCM metabolites, s-adenosylmethionine (SAM), s-adenosylhomocysteine (SAH) and Hcy, and diet. Associations between OCM metabolites and MetS features were also investigated. In an 8-week human cross-over intervention study we investigated whether a diet rich in whole grain compared to a diet ri ...
Acid – base balance
... All the known low molecular weight and water soluble biosynthetic intermediates possess groups that are almost completely ionised at neutral pH’ ...
... All the known low molecular weight and water soluble biosynthetic intermediates possess groups that are almost completely ionised at neutral pH’ ...
An Advanced Technique in Biomedical Sciences - e
... MS (LC-MS) with a triple quadrupole system [5]. Tandem MS is also preferred by many workers because for ensuring added specificity in drugs. The pharmacokinetics i.e. bioavailability or level of drug samples at different time points and the clearance rate from the body can easily be monitored using ...
... MS (LC-MS) with a triple quadrupole system [5]. Tandem MS is also preferred by many workers because for ensuring added specificity in drugs. The pharmacokinetics i.e. bioavailability or level of drug samples at different time points and the clearance rate from the body can easily be monitored using ...
Medicine "Lactobacterin" is a microbial mass of antagonistically
... Lactic acid bacteria (Lactobacilli) are the microorganisms which are the main part of the normal human intestinal micro flora. They have saccharolytic type of metabolism [1,2]. They have good antagonistic activity against pathogenic microorganisms [3]. Lactobacilli are used not only in medicine, as ...
... Lactic acid bacteria (Lactobacilli) are the microorganisms which are the main part of the normal human intestinal micro flora. They have saccharolytic type of metabolism [1,2]. They have good antagonistic activity against pathogenic microorganisms [3]. Lactobacilli are used not only in medicine, as ...
Organix - Interpretive Guide
... support program. For many of the organic acids that are measured, abnormally high levels in urine may indicate low levels of a vitamin needed to break down that compound. This booklet translates abnormalities of organic acids into information about areas where you may need extra nutrients, or a chan ...
... support program. For many of the organic acids that are measured, abnormally high levels in urine may indicate low levels of a vitamin needed to break down that compound. This booklet translates abnormalities of organic acids into information about areas where you may need extra nutrients, or a chan ...
Guidelines for the Investigation of Hyperammonaemia
... Specialised investigations to investigate hyperammonaemia The suspicion that hyperammonaemia is due either to urea cycle defects or secondary to other metabolic disorders should prompt early contact with the regional metabolic centre to coordinate more specialised investigations and clinical managem ...
... Specialised investigations to investigate hyperammonaemia The suspicion that hyperammonaemia is due either to urea cycle defects or secondary to other metabolic disorders should prompt early contact with the regional metabolic centre to coordinate more specialised investigations and clinical managem ...
Carnitine-acylcarnitine translocase deficiency: metabolic
... All enzymes were measured according to published procedures as reviewed by Wanders et al. [20]. The activity of very-long-chain acyl-CoA dehydrogenase (VLCAD) was measured spectrophotometrically using ferricenium [21]. EnoylCoA hydratase activity was measured spectrophotometrically at 340 nm using c ...
... All enzymes were measured according to published procedures as reviewed by Wanders et al. [20]. The activity of very-long-chain acyl-CoA dehydrogenase (VLCAD) was measured spectrophotometrically using ferricenium [21]. EnoylCoA hydratase activity was measured spectrophotometrically at 340 nm using c ...
Detoxification mechanisms (Apis mellifera) resulting in tolerance of dietary nicotine
... genes encoding for these enzyme families relative to other insect genomes11. A comprehensive review of available pesticide toxicity data12 found that while honey bees can be sensitive to individual insecticides, in general they are no more vulnerable than other insect species. However, it has been s ...
... genes encoding for these enzyme families relative to other insect genomes11. A comprehensive review of available pesticide toxicity data12 found that while honey bees can be sensitive to individual insecticides, in general they are no more vulnerable than other insect species. However, it has been s ...
Rest to Exercise Transition
... – Oxygen debt that needs to be repaid (anaerobic metabolism) – Lactic acid is a “dead-end metabolite” that is formed but not removed during exercise – Elevated blood La represents oxygen insufficiency in ...
... – Oxygen debt that needs to be repaid (anaerobic metabolism) – Lactic acid is a “dead-end metabolite” that is formed but not removed during exercise – Elevated blood La represents oxygen insufficiency in ...
Elemental Analysis
... The detection of individual elements in a mixture with other accompanying elements is a rather difficult problem, because all of them can interact with the same reagents with a similar outward effect. Using specific reagents and reactions, makes it possible to detect some elements in mixtures with a ...
... The detection of individual elements in a mixture with other accompanying elements is a rather difficult problem, because all of them can interact with the same reagents with a similar outward effect. Using specific reagents and reactions, makes it possible to detect some elements in mixtures with a ...
Chem 324 Expt 6 (Revised): Green Chemistry: Allylation of Benzoin
... Alllylation. According to Tan:2 “Typical procedures for the allylation are as follows: To a mixture of carbonyl compound (10 mmol) and allyl halide (15 mmol) in water (20 ml), copper powder (20 mmol) and SnCl2 (20 mmol) were added in one portion. The mixture was vigorously stirred at room temperatur ...
... Alllylation. According to Tan:2 “Typical procedures for the allylation are as follows: To a mixture of carbonyl compound (10 mmol) and allyl halide (15 mmol) in water (20 ml), copper powder (20 mmol) and SnCl2 (20 mmol) were added in one portion. The mixture was vigorously stirred at room temperatur ...
Drug Absorption, Distribution, Metabolism, Elimination - A
... Biotransform’n Drug Molecules • Drug changed chem’ly metabolite – Prodrugs must be metab’d for act’n ...
... Biotransform’n Drug Molecules • Drug changed chem’ly metabolite – Prodrugs must be metab’d for act’n ...
GeneCensus - Gerstein Lab Publications
... organisms included in the tree server provide for diverse phylogenetic comparisons. They encompass all three kingdoms of life (Eukarya, Bacteria, Archaea), diverse environments (normal to extreme), and a wide range of genome sizes (0.6-97Mbp). The architecture of the tree server is two-dimensional. ...
... organisms included in the tree server provide for diverse phylogenetic comparisons. They encompass all three kingdoms of life (Eukarya, Bacteria, Archaea), diverse environments (normal to extreme), and a wide range of genome sizes (0.6-97Mbp). The architecture of the tree server is two-dimensional. ...
Selective Isotope-Labeling Methods for Protein Structural Studies
... In addition to uniform (13C / 15N / 2H) labeling, amino acid-type or site-selective labeling is often pursued as it helps in spectral simplification and provides specific probes for structural and dynamic studies. Selective amino acid-type labeling also aids in sequence-specific resonance assignment ...
... In addition to uniform (13C / 15N / 2H) labeling, amino acid-type or site-selective labeling is often pursued as it helps in spectral simplification and provides specific probes for structural and dynamic studies. Selective amino acid-type labeling also aids in sequence-specific resonance assignment ...
Understanding Labratory Teating - A Parent`s
... anxiety, depression, or obsessive-compulsive disorder. Anti-psychotic medications are used to treat severe behavioral problems. Seizures can be treated with one or more of the anticonvulsant drugs. Stimulant drugs, such as those used for children with attention deficit disorder (ADD), are sometimes ...
... anxiety, depression, or obsessive-compulsive disorder. Anti-psychotic medications are used to treat severe behavioral problems. Seizures can be treated with one or more of the anticonvulsant drugs. Stimulant drugs, such as those used for children with attention deficit disorder (ADD), are sometimes ...
anatomic and physiologic considerations for reptil
... cavum pulmonale and cavum dorsale. However, during ventricular systole the muscular ridge presses against the dorsal wall of the ventricle and separates the cavum pulmonale from the cavum dorsale, thus although exhibiting anatomical continuity of the subchambers, the heart is capable of acting as a ...
... cavum pulmonale and cavum dorsale. However, during ventricular systole the muscular ridge presses against the dorsal wall of the ventricle and separates the cavum pulmonale from the cavum dorsale, thus although exhibiting anatomical continuity of the subchambers, the heart is capable of acting as a ...
Production of the Novel Lipopeptide Antibiotic Trifluorosurfactin via
... characteristics or improving their biological activity. ...
... characteristics or improving their biological activity. ...
Mixotrophic and photoheterotrophic metabolism in
... The unicellular diazotrophic cyanobacterium Cyanothece sp. ATCC 51142 (Cyanothece 51142) is able to grow aerobically under nitrogen-fixing conditions with alternating light–dark cycles or continuous illumination. This study investigated the effects of carbon and nitrogen sources on Cyanothece 51142 ...
... The unicellular diazotrophic cyanobacterium Cyanothece sp. ATCC 51142 (Cyanothece 51142) is able to grow aerobically under nitrogen-fixing conditions with alternating light–dark cycles or continuous illumination. This study investigated the effects of carbon and nitrogen sources on Cyanothece 51142 ...
Teaching metabolic pathways
... memorization. Even worse, some teachers present the subject in this manner. Modern biochemistry is much more than a catalogue of molecular structures and chemical reactions. The chemistry of life has unifying principles and concepts, eloquently described by LehningerI as the "molecular logic of livi ...
... memorization. Even worse, some teachers present the subject in this manner. Modern biochemistry is much more than a catalogue of molecular structures and chemical reactions. The chemistry of life has unifying principles and concepts, eloquently described by LehningerI as the "molecular logic of livi ...