• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Arterial Blood Gas Interpretation: The Basics
Arterial Blood Gas Interpretation: The Basics

... SO2 stands for oxygen saturation or percentage of hemoglobin combined with oxygen. In ABG results, SO2 is derived from PO2 using the oxygen-hemoglobin dissociation curve. It can also be measured using a pulse oximeter. SO2 may be as low as 90% in healthy patients of advanced age. ...
Solid state NMR of isotope labelled murine fur: A powerful tool to
Solid state NMR of isotope labelled murine fur: A powerful tool to

... are embedded in a matrix containing proteins with high levels of glycine and tyrosine, and cysteine, termed keratin associated proteins (KAPs). In hard tissues, the head and tail domains of the keratin proteins crosslink with the matrix. Solid state NMR (ssNMR) has been applied to characterize, comp ...
Slides
Slides

... each P in U:   If current organism is outside taxonomic range of P AND at least one reaction in P lacks an enzyme, delete P from U   If all reactions of P designated as key reactions have no enzyme, delete P from U ...
Załącznik nr 3 do Zarządzenia Rektora PUM…………………….. z
Załącznik nr 3 do Zarządzenia Rektora PUM…………………….. z

... of DNA and RNA (primary and secondary) and chromatin structure knows functions of genome, transcriptome and proteome as well as basic methods applied to investigate these; describes processes of DNA replication, repair and recombination, processes of transcription and translation also the processes ...
Flux-balance Analysis - Systems Biology Research Group
Flux-balance Analysis - Systems Biology Research Group

... Characteristics of defined phases: The regions of the phase plane can be defined based on the contribution of the two substrates to the overall objective function: In regions where the α value is negative, there is dual limitation of the substrates. Based on the absolute value of α , the substrate w ...
Document
Document

... Subsequent catabolism of the tiglylCoA formed from L-isoleucine. ...
Medical Endocrine Course
Medical Endocrine Course

... Outline the components of appropriate therapeutic lifestyle changes. Describe the role of lipoprotein analysis in the initial evaluation and long-term management of patients with lipid disorders, and list the major modifiable and nonmodifiable risk factors for coronary heart disease (CHD). Describe ...
The genomes of four tapeworm species reveal adaptations to
The genomes of four tapeworm species reveal adaptations to

... 3.1, 3.2 and 3.3), consistent with previous observations of karyotype plasticity in flatworms11. Aided by deep transcriptome sequencing from multiple life-cycle stages, we identified 10,231 to 12,490 putative genes per genome (Supplementary Table 5.5). Similar to the genome of S. mansoni12, distinct ...
Industrial biotechnology: Tools and applications
Industrial biotechnology: Tools and applications

... “Omics” and in silico approaches Increased genome sequencing efforts have ushered in a new era of systems biology, in which entire cellular networks are analyzed and optimized for application in the development of strains and bioprocesses. The properties of these complex cellular networks cannot be ...
Systembiologische Ansätze zur Erforschung des Metabolismus
Systembiologische Ansätze zur Erforschung des Metabolismus

... (cooperation with Maria Mittag, Jena) • Circadian rhythm was taken into account by three distinct phases (i.e., sets of conditions) • In day-phase, ATP and NADH are sufficiently available, thus set to external status • In first phase of night, ATP and NADH need to be balanced (are internal), while t ...
1 22,25 October 2004 Physiology of Locomotion R. B. Huey I. Some
1 22,25 October 2004 Physiology of Locomotion R. B. Huey I. Some

... physiologically “clean” and efficient, can sustain modest work loads for very long periods. But at higher work loads, ATP demands exceed the capacity of aerobic pathways (“anaerobic threshold”) and anaerobic metabolism kicks in. Although anaerobic pathways can produce lots of ATP quickly, they are n ...
PURINE Lacture
PURINE Lacture

... * when the base is purine, then the nucleoside ends in OSINE (AdenOSINE, GuanOSINE, InOSINE) ...
Central carbon metabolism of Saccharomyces
Central carbon metabolism of Saccharomyces

... has been described previously [1,5]. Briefly, f (1) represents the fraction of molecules in which the observed carbon atom and its neighbouring carbons originate from different source molecules of glucose, and f (2) the fraction of molecules in which the observed carbon atom and at least one neighbo ...
The Proteomics Big Challenge for Biomarkers and New Drug
The Proteomics Big Challenge for Biomarkers and New Drug

... from functional, chemical and clinical proteomics to drug discovery development are underlined. In the complex drug discovery scenario, the various MS-based proteomic approaches extend beyond the common objective of drug target discovery, enabling the study of drug-target interaction (selectivity an ...
AODA Resource Guide - Green Bay Police Department
AODA Resource Guide - Green Bay Police Department

...  When you are waiting for the help to arrive, make sure that the ambulance personnel have free access to the scene.  Make sure the ambulance personnel know where to come.  If possible, leave the door open or ask someone to wait on the street and give directions.  When the ambulance personnel ar ...
Adenosine Triphosphate (ATP) and Metabolic Systems (cont`d)
Adenosine Triphosphate (ATP) and Metabolic Systems (cont`d)

... • Low calorie diets have the opposite effect. Decreasing calories can decrease RMR and lead to weight can. ...
Movsumov I.S., Garayev E.A. STUDYING OF CHEMICAL
Movsumov I.S., Garayev E.A. STUDYING OF CHEMICAL

... The chemical state analysis of carboxyl groups in structural links of polyuronide compounds for four kinds of a linen fibre of domestic (Kaluga, Vologda, Biysk) and import (Dutch) manufactures by infrared spectroscopy method of pectin films having been carried out. The reception of consecutive trans ...
Results - BioMed Central
Results - BioMed Central

... little thick after 15 days, at this point, the inoculated tissue surface was covered with ...
heling patients with personal hygiene
heling patients with personal hygiene

... and functions. The oral cavity contains the tongue, the lips, the teeth, and the openings to the salivary glands. The mouth connects in its posterior to the pharynx, which is the first section of the digestive tract. The mouth also connects with the trachea, which is the first section of the respira ...
the use of bayesian statistics in mass spectrometry data
the use of bayesian statistics in mass spectrometry data

... considered to be the birth of mass spectrometry, and important features discussed by Thomson still remain relevant [5]. Through mass spectrometry, scientists are able to measure atomic and molecular weights of species in complex samples, analyze compounds at low level samples, as well as analyze com ...
Industrial Biotechnology
Industrial Biotechnology

... • This is the simplest of the three, and the driving force is the difference in concentration of the solute across the border. • The carrier in the membrane merely helps increase the rate of passage through the membrane, and not the final concentration in the cell. • (ii) Active transport: • This oc ...
Metabolic Impairment in Heart Failure
Metabolic Impairment in Heart Failure

... issues for skeletal muscle metabolism in HF need to be addressed: 1) impaired energy metabolism affecting contractile function; and 2) structural metabolism to balance the body’s protein pool. Indeed, a generalized metabolic myopathy, characterized by decreased oxidative capacity, impaired substrate ...
Living on the edge: substrate competition explains loss of
Living on the edge: substrate competition explains loss of

... therefore compete for common enzymes. Since each enzyme molecule can only bind one substrate molecule at a time, the alternative substrates for the same enzyme act as competitive inhibitors. MCAD, for instance, catalyzes the dehydrogenation of acyl-CoA esters of 4 to 12 carbon atoms (Fig. 1a). The d ...
Learning Objectives
Learning Objectives

... Fatty acid synthase All enzyme activities on one enzyme Addition of malonyl CoA each time Uses NADPH Understand regulation of lipid metabolism by Committed steps Hormones Cholesterol synthesis Important enzyme = HMG CoA reductase (how regulated?) High cholesterol and heart disease Use of lovastatin ...
Exam Procedures: this isBMB 514 Exam #2 10/8/12 this is form A
Exam Procedures: this isBMB 514 Exam #2 10/8/12 this is form A

... (b) pKa values of functional groups; and (c) table of logarithms.  Read each question very carefully. Choose the single, best answer and mark this answer on your answer sheet. No points will be added for correct answers which appear on the exam page but not on the answer sheet.  A simple calculato ...
< 1 ... 26 27 28 29 30 31 32 33 34 ... 78 >

Pharmacometabolomics

Pharmacometabolomics, also known as pharmacometabonomics, is a field which stems from metabolomics, the quantification and analysis of metabolites produced by the body. It refers to the direct measurement of metabolites in an individual’s bodily fluids, in order to predict or evaluate the metabolism of pharmaceutical compounds, and to better understand the pharmacokinetic profile of a drug. Alternatively, pharmacometabolomics can be applied to measure metabolite levels following the administration of a pharmaceutical compound, in order to monitor the effects of the compound on certain metabolic pathways(pharmacodynamics). This provides detailed mapping of drug effects on metabolism and the pathways that are implicated in mechanism of variation of response to treatment. In addition, the metabolic profile of an individual at baseline (metabotype) provides information about how individuals respond to treatment and highlights heterogeneity within a disease state. All three approaches require the quantification of metabolites found in bodily fluids and tissue, such as blood or urine, and can be used in the assessment of pharmaceutical treatment options for numerous disease states.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report