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BL414 Genetics Spring 2006 Linkage and Genetic Maps Outline February 22, 2006
BL414 Genetics Spring 2006 Linkage and Genetic Maps Outline February 22, 2006

... In the principle of independent assortment, we saw that the two parental alleles have a 50/50 chance of being transmitted to offspring. For example, the cross of Dd x dd gives offspring with a 50/50 chance of getting the D or d allele from one parent, and a 100% of getting d from the other parent, s ...
The Role of Model Organisms in the History of Mitosis
The Role of Model Organisms in the History of Mitosis

... morphological (cell structural) event, and a number of visible cell structural mitotic markers have been proposed, such as nuclear membrane disassembly, chromosome condensation, spindle formation, kinetochore microtubule formation, etc. (see Fig. 2). The end of mitosis is also ambiguous. In telophas ...
What is Cytogenetics?
What is Cytogenetics?

... material (translocation) between the long arms of chromosomes 9 and 22 e.g. t(9;22) • This translocation brings together the BCR gene on chromosome 22 and the ABL gene on chromosome 9 • The resulting hybrid gene BCR/ABL causes uncontrolled cell growth ...
prenatal development
prenatal development

... Meiosis is Sex Cell (Gamete) Formation  In sexually reproducing organisms, some cells are able to divide by another ...
The Mitotic Arrest in Response to Hypoxia and of Polar Bodies
The Mitotic Arrest in Response to Hypoxia and of Polar Bodies

... through the syncytial cycles or not. During wild-type development, the innermost one of the four haploid nuclei generated by female meiosis develops into the pronucleus, whereas the peripheral, outer three polar body nuclei become reorganized into a characteristic condensed chromosome bouquet [30]. ...
Lecture 15 – PDF
Lecture 15 – PDF

... C. Now consider crossing over – physical exchange between homologous pair of chromosomes 1. In the dihybrid AB/ab a) If there is no crossing over between genes A & B, gametes are AB and ab → parental types b) If there is crossing over between genes A & B, gametes are Ab and aB → recombinant types c) ...
Chapter 15 ppt
Chapter 15 ppt

... • Mendel’s “hereditary factors” were genes, though this wasn’t known at the time • Today we can show that genes are located on chromosomes • The location of a particular gene can be seen by tagging isolated chromosomes with a fluorescent dye that highlights the gene ...
CHAPTER 15
CHAPTER 15

... Sturtevant used the testcross design to map the relative positions of three fruit fly genes: body color (b), wing size (vg), and eye color (cn). o Cinnabar (cn), one of many Drosophila genes affecting eye color, results in a bright red eye. o The recombination frequency between cn and b is 9%. o The ...
AP Review
AP Review

... – Cell division has two phases • Nuclear division (either mitosis or meiosis) and cytokinesis – Mitosis » One cell  two identical diploid daughter cells – Meiosis (reduction division) » One cell  4 non identical haploid cells ...
The Chromosomal Basis of Inheritance
The Chromosomal Basis of Inheritance

... Sturtevant used the testcross design to map the relative positions of three fruit fly genes: body color (b), wing size (vg), and eye color (cn). o Cinnabar (cn), one of many Drosophila genes affecting eye color, results in a bright red eye. o The recombination frequency between cn and b is 9%. o The ...
CHAPTER 15
CHAPTER 15

... Under normal Mendelian genetic rules, we would not expect linked genes to recombine into assortments of alleles not found in the parents.  If the seed color and seed coat genes were linked, we would expect the F1 offspring to produce only two types of gametes, YR and yr, when the tetrads separate. ...
To play movie you must be in Slide Show Mode
To play movie you must be in Slide Show Mode

...  Many flowering plants, and some insects, fishes and other animals are polyploid – having three or more of each type of chromosome characteristic of the species  Chromosome number can change permanently, usually resulting from nondisjunction – the failure of chromosomes to separate normally during ...
Biol 1406 notes Ch 15 8thed
Biol 1406 notes Ch 15 8thed

... conform to either independent assortment or complete linkage. o Under independent assortment, the testcross should produce a 1:1:1:1 phenotypic ratio. o Under complete linkage, we should expect to see a 1:1:0:0 ratio, with only parental phenotypes among the offspring.  Most of the offspring had par ...
Multiregional origin of B chromosomes in the grasshopper
Multiregional origin of B chromosomes in the grasshopper

... actually exists that the B arose from the X and later acquired the 18S-5.8S-28S rDNA. As Hewitt (1973) suggested, X and small autosomes are the most likely sources of B chromosomes because they are best tolerated as polysomic elements. Although the multiregional origin of B chromosomes in E. plorans ...
Review A model for chromosome structure during the mitotic
Review A model for chromosome structure during the mitotic

... During G2, chromatin is diffuse, consisting of 10and 30-nm-diameter chromatin ¢bers. Sister DNA (chromatin) loops extend in opposite directions from duplicated but closely associated sister matrix strands (Figure 7). A G2 chromosome occupies a cylinder of space in the nucleus. DNA loops of each sist ...
Tissue-specific spatial organization of genomes
Tissue-specific spatial organization of genomes

... nonrandom nature of genome organization is also reflected in the positioning of chromosomes relative to each other [10]. For example, in a lymphoma cell line derived from an ATM-/mouse, two translocated chromosomes are preferentially positioned in close proximity to each other and the three chromoso ...
Life Sciences P2 GR 12 Exemplar 2014 Eng Memo
Life Sciences P2 GR 12 Exemplar 2014 Eng Memo

... internal moderator who in turn will consult with the national internal moderator (and the Umalusi moderators where necessary). ...
7th Grade Science Formative Assessment #6 Multiple Choice
7th Grade Science Formative Assessment #6 Multiple Choice

... A. All four offspring received all of their genetic information only from Parent 1 and are therefore identical to that parent. B. All four offspring received all of their genetic information only from Parent 2 and are therefore identical to that parent. C. Each of the offspring is genetically unique ...
BIOLOGY/SEMESTER 1
BIOLOGY/SEMESTER 1

... Metaphase- condensed chromosomes line up on the equator of the cell, spindle fibers link the chromatids to opposite poles. Anaphase- spindle fibers shorten, chromatids are pulled to opposite to opposite ends of the cell. Telophase- nuclear envelope forms at each pole, spindle dissolves, chromosomes ...
Warm-up - Cloudfront.net
Warm-up - Cloudfront.net

... Homologous chromosomes are chromosomes that carry the same genes; one of the chromosomes will come from the mother, and one will have come from the father. During meiosis, the homologous chromosomes will go separately into each gamete. This is the process of Independent Assortment. Since each set of ...
Parallel Machine Scheduling with Sequence
Parallel Machine Scheduling with Sequence

... Population(t) Selection picks Crossover some creates Mutation changes a chromosomes new as chromosomes by small number of genes potential parents taking genes in infrom ...
Chapter. 15(Chromosomal Basis of Inheritance)
Chapter. 15(Chromosomal Basis of Inheritance)

... • Such genes are physically linked, but genetically unlinked, and behave as if found on different chromosomes. • Sturtevant used recombination frequencies to make linkage maps of fruit fly genes. • Using methods like chromosomal banding, geneticists can develop cytogenetic maps of chromosomes. • Cyt ...
Nerve activates contraction
Nerve activates contraction

... Organisms with more than two complete sets of chromosomes, have undergone polypoidy. One gamete has Nondisjunction of all its chromosomes.  The resulting zygote would be triploid (3n). 2n gametes + self –fertilization = a tetraploid (4n) embryo ...
TEXT The cell cycle, or cell-division cycle, is the series of events that
TEXT The cell cycle, or cell-division cycle, is the series of events that

... case for neurons). This is very common for cells that are fully differentiated. Cellular senescence is a state that occurs in response to DNA damage or degradation that would make a cell's progeny nonviable; it is often a biochemical alternative to the self-destruction of such a damaged cell by apop ...
The Diversity of Life
The Diversity of Life

... 2. How do cells in your body get energy? 3. How do you think the change in chlorophyll levels is a response to changes in the length of day from summer to fall? Lesson 6 ...
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Meiosis



Meiosis /maɪˈoʊsɨs/ is a specialized type of cell division which reduces the chromosome number by half. This process occurs in all sexually reproducing single-celled and multi-celled eukaryotes, including animals, plants, and fungi. Errors in meiosis resulting in aneuploidy are the leading known cause of miscarriage and the most frequent genetic cause of developmental disabilities. In meiosis, DNA replication is followed by two rounds of cell division to produce four daughter cells each with half the number of chromosomes as the original parent cell. The two meiotic divisions are known as meiosis I and meiosis II. Before meiosis begins, during S phase of the cell cycle, the DNA of each chromosome is replicated so that it consists of two identical sister chromatids. In meiosis I, homologous chromosomes pair with each other and can exchange genetic material in a process called chromosomal crossover. The homologous chromosomes are then segregated into two new daughter cells, each containing half the number of chromosomes as the parent cell. At the end of meiosis I, sister chromatids remain attached and may differ from one another if crossing-over occurred. In meiosis II, the two cells produced during meiosis I divide again. Sister chromatids segregate from one another to produce four total daughter cells. These cells can mature into various types of gametes such as ova, sperm, spores, or pollen.Because the number of chromosomes is halved during meiosis, gametes can fuse (i.e. fertilization) to form a zygote with a complete chromosome count containing a combination of paternal and maternal chromosomes. Thus, meiosis and fertilization facilitate sexual reproduction with successive generations maintaining the same number of chromosomes. For example, a typical diploid human cell contains 23 pairs of chromosomes (46 total, half of maternal origin and half of paternal origin). Meiosis produces haploid gametes with one set of 23 chromosomes. When two gametes (an egg and a sperm) fuse, the resulting zygote is once again diploid, with the mother and father each contributing 23 chromosomes. This same pattern, but not the same number of chromosomes, occurs in all organisms that utilize meiosis. Thus, if a species has 30 chromosomes in its somatic cells, it will produce gametes with 15 chromosomes.
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