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College of Medicine Microbiology
College of Medicine Microbiology

... such as rhinovirus which has more than 100 serotypes , this is the reason why the common cold by this virus is common.  Antigenic variation may occur in certain viruses have multiple antigenic types such influenza virus undergo changes in surface antigens.  Certain viruses are able to thwart immun ...
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... Continuous culture methods enable constant cell numbers to be maintained in a constant chemical environment at specified growth rates for prolonged periods of time Fed-batch Fed-batch culture is, in the broadest sense, defined as an operational technique in biotechnological processes where one or mo ...
pinter`s - Rutgers New Jersey Medical School
pinter`s - Rutgers New Jersey Medical School

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Bio244 Lecture Exam 3 Study Guide (Ch. 5, 9, 10) pg.1 Ch. 5 (An

... Know  the  following  concepts:   1. Know  that  viruses  have  the  capability  to  infect  every  cellular  organism   2. Know  what  is  meant  by  “filterable  viruses”   3. Understand  the  role  viruses  have  played  in  the  evoluti ...
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Influenza A virus



Influenza A virus causes influenza in birds and some mammals, and is the only species of influenza virus A. Influenza virus A is a genus of the Orthomyxoviridae family of viruses. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics.Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses.The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N1 to N11). H17 was isolated from fruit bats in 2012. H18N11 was discovered in a Peruvian bat in 2013.Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.A filtered and purified influenza A vaccine for humans has been developed, and many countries have stockpiled it to allow a quick administration to the population in the event of an avian influenza pandemic. Avian influenza is sometimes called avian flu, and colloquially, bird flu. In 2011, researchers reported the discovery of an antibody effective against all types of the influenza A virus.
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