guide to shipping biological substances and support materials
... An infectious substance, other than a Category A infectious substance (See Section 10.3.2.1), contained in a patient sample being transported for research, diagnosis, investigational activities, or disease treatment and prevention, or a biological product, when such materials are being transported ...
... An infectious substance, other than a Category A infectious substance (See Section 10.3.2.1), contained in a patient sample being transported for research, diagnosis, investigational activities, or disease treatment and prevention, or a biological product, when such materials are being transported ...
Appendix 2: Zika Virus Factsheet
... Reports from several countries, most notably Brazil, where ZIKV outbreaks have occurred, indicate a coincident increase in cases of congenital abnormalities, some of which are severe, and include microcephaly.24, 25, 52, 53 Based on current evidence, the risk of congenital abnormalities appears to r ...
... Reports from several countries, most notably Brazil, where ZIKV outbreaks have occurred, indicate a coincident increase in cases of congenital abnormalities, some of which are severe, and include microcephaly.24, 25, 52, 53 Based on current evidence, the risk of congenital abnormalities appears to r ...
Hendra Virus - SoNG - Department of Health
... been fatal. One of the human deaths occurred 13 months after exposure to the virus, which occurred during the post-mortem examination of an affected horse. Notably, this case was hospitalised with aseptic meningitis shortly after exposure (see Case 3, Appendix 1). All seven cases had a high level of ...
... been fatal. One of the human deaths occurred 13 months after exposure to the virus, which occurred during the post-mortem examination of an affected horse. Notably, this case was hospitalised with aseptic meningitis shortly after exposure (see Case 3, Appendix 1). All seven cases had a high level of ...
Replication of hepatitis C virus in peripheral blood mononuclear
... ve prognostic factor [2]. Surprisingly, in our study patients who had detectable HCV RNA negative strand in PBMCs before treatment had a higher rate of SVR (p=0.062). This potentially beneficial influence of negative strand presence on SVR rate is unclear. Different hypotheses of mechanisms concerni ...
... ve prognostic factor [2]. Surprisingly, in our study patients who had detectable HCV RNA negative strand in PBMCs before treatment had a higher rate of SVR (p=0.062). This potentially beneficial influence of negative strand presence on SVR rate is unclear. Different hypotheses of mechanisms concerni ...
Recombinant adeno-associated virus purification using
... dripping from the bottom and collecting 1 ml fractions for detailed analysis. The bulk of the rAAV virus bands within the 40% density step (Figure 3c, fractions 5–8). A heavy band that migrates at the 40%-to-25% density junction consists mostly of cellular proteins (Figure 3c, fractions 9 and 10) an ...
... dripping from the bottom and collecting 1 ml fractions for detailed analysis. The bulk of the rAAV virus bands within the 40% density step (Figure 3c, fractions 5–8). A heavy band that migrates at the 40%-to-25% density junction consists mostly of cellular proteins (Figure 3c, fractions 9 and 10) an ...
Recommendations for immunization of solid organ transplant
... A and yellow fever also indicate immunity. Based on these results a catch-up schedule can be designed, including required booster doses. In patients with end-stage organ disease, antibody levels should be determined again after immunization to document vaccine-induced immunity. Specific antibody lev ...
... A and yellow fever also indicate immunity. Based on these results a catch-up schedule can be designed, including required booster doses. In patients with end-stage organ disease, antibody levels should be determined again after immunization to document vaccine-induced immunity. Specific antibody lev ...
Shingles - Snohomish Health District
... rash appears as a band or patch of raised bumps on the side of the body or face. It then develops into small, fluid-filled blisters that dry out and crust over within a few days. When the rash is at its peak, symptoms can range from mild itching to severe pain. The rash and pain usually disappear wi ...
... rash appears as a band or patch of raised bumps on the side of the body or face. It then develops into small, fluid-filled blisters that dry out and crust over within a few days. When the rash is at its peak, symptoms can range from mild itching to severe pain. The rash and pain usually disappear wi ...
Development of single serum dilution ELISA for detection of
... reaction (slope) was directly proportionate to the quantity of the reaction curve, the higher the titre of the antibody. BRIGGS et al. (1986) used positive/negative (P/N) ratio method of analysis to quantitate antibody response to IBDV. In this study an indigenous SSD-ELISA kit was developed and the ...
... reaction (slope) was directly proportionate to the quantity of the reaction curve, the higher the titre of the antibody. BRIGGS et al. (1986) used positive/negative (P/N) ratio method of analysis to quantitate antibody response to IBDV. In this study an indigenous SSD-ELISA kit was developed and the ...
West Nile virus infection in reindeer (Rangifer tarandus)
... in North America in the summer of 1999 in the New York City metropolitan area, during an epizootic involving birds, horses, and humans. Each summer and fall since 1999, the geographic range of WNV in North America has continued to expand westward.12 The WNV isolate responsible for the initial epizoo ...
... in North America in the summer of 1999 in the New York City metropolitan area, during an epizootic involving birds, horses, and humans. Each summer and fall since 1999, the geographic range of WNV in North America has continued to expand westward.12 The WNV isolate responsible for the initial epizoo ...
Chapter 12: Viral Diseases - Laboratory Animal Boards Study Group
... True or False: Replication of single-stranded RNA viruses is more error-prone than that of DNA viruses leading to emergence of divergent strains during natural infection. True or False: Several RCV isolates have been reported since the initial isolations by Parker and Bhatt. RCV induces what cytopat ...
... True or False: Replication of single-stranded RNA viruses is more error-prone than that of DNA viruses leading to emergence of divergent strains during natural infection. True or False: Several RCV isolates have been reported since the initial isolations by Parker and Bhatt. RCV induces what cytopat ...
Chapter 27 SMALLPOX
... encoding the nonessential functions important for virus virulence are arrayed near the ends of the genome; as would be expected, the greatest heterogeneity between poxviruses is at these genomic ends. 23,24 There are 187 putative proteins identified from the sequencing of variola virus, of which 150 ...
... encoding the nonessential functions important for virus virulence are arrayed near the ends of the genome; as would be expected, the greatest heterogeneity between poxviruses is at these genomic ends. 23,24 There are 187 putative proteins identified from the sequencing of variola virus, of which 150 ...
Importation of cooked turkey meat from the United States
... parts passed for cooking (FDA 2014), which requires cooking of poultry parts ‘to a temperature not lower than 170 °F (76.6 °C) for a period of not less than 30 minutes. In this draft review the definition of turkey meat is limited to muscle tissue from any domestic turkey (Meleagris gallopava), bloo ...
... parts passed for cooking (FDA 2014), which requires cooking of poultry parts ‘to a temperature not lower than 170 °F (76.6 °C) for a period of not less than 30 minutes. In this draft review the definition of turkey meat is limited to muscle tissue from any domestic turkey (Meleagris gallopava), bloo ...
A virus behind the mask of prions?
... This makes their conclusions about a lack of TSE nucleic acids suspect. In any case, the recovery of 10–20 ng of nucleic acid from these new infectious scrapie preparations [58a] surely contradicts the statement that “no detectable nucleic acids of any kind have been associated with prions” [57]. Ho ...
... This makes their conclusions about a lack of TSE nucleic acids suspect. In any case, the recovery of 10–20 ng of nucleic acid from these new infectious scrapie preparations [58a] surely contradicts the statement that “no detectable nucleic acids of any kind have been associated with prions” [57]. Ho ...
Is swine flu
... or sneeze), but others think the better use for masks would be on those people who have symptoms and sneeze or cough. The use of Tamiflu or Relenza may help prevent the flu if taken before symptoms develop or reduce symptoms if taken within about 48 hours after symptoms develop. Some investigators s ...
... or sneeze), but others think the better use for masks would be on those people who have symptoms and sneeze or cough. The use of Tamiflu or Relenza may help prevent the flu if taken before symptoms develop or reduce symptoms if taken within about 48 hours after symptoms develop. Some investigators s ...
Appendix C. Pathogen Characteristics 1
... Infectious dose for GI anthrax is unknown. In animal models (guinea pigs, rabbits and monkeys) ...
... Infectious dose for GI anthrax is unknown. In animal models (guinea pigs, rabbits and monkeys) ...
Ebola haemorrhagic fever
... to be potential reservoir species. This idea was supported by experimental studies in African plants and animals that resulted in productive infection of African fruit and insectivorous bats with Zaire Ebola virus, but a firm link could not be established.29 The first evidence for the presence of Zair ...
... to be potential reservoir species. This idea was supported by experimental studies in African plants and animals that resulted in productive infection of African fruit and insectivorous bats with Zaire Ebola virus, but a firm link could not be established.29 The first evidence for the presence of Zair ...
Related File - One Health Commission
... Hendra virus (HeV) is an emerging zoonotic paramyxovirus for which natural reservoirs are the 4 species of flying fox (Pteropus bats) found on mainland Australia (1 (#r1) ). HeV was discovered in 1994, and since then, infections have occurred in 7 humans, 4 of whom died. Each case-patient had a stro ...
... Hendra virus (HeV) is an emerging zoonotic paramyxovirus for which natural reservoirs are the 4 species of flying fox (Pteropus bats) found on mainland Australia (1 (#r1) ). HeV was discovered in 1994, and since then, infections have occurred in 7 humans, 4 of whom died. Each case-patient had a stro ...
HVT recombinant vaccines are new to the poultry industry. Follow
... INNOVAX-ILT-SB uses the same rHVT-ILT but is also combined with a conventional serotype 2 SB1 Marek’s Disease vaccine. ...
... INNOVAX-ILT-SB uses the same rHVT-ILT but is also combined with a conventional serotype 2 SB1 Marek’s Disease vaccine. ...
PDF
... NS5B, the viral RNA-dependent RNA polymerase is the key enzyme of the replicase complex [10,11]. Using the (+) strand genome as a template, NS5B first synthesizes a complementary (−) strand, resulting in a double-stranded (ds) RNA intermediate, and then proceeds to transcribing progeny (+) strands. ...
... NS5B, the viral RNA-dependent RNA polymerase is the key enzyme of the replicase complex [10,11]. Using the (+) strand genome as a template, NS5B first synthesizes a complementary (−) strand, resulting in a double-stranded (ds) RNA intermediate, and then proceeds to transcribing progeny (+) strands. ...
Early warning and response in Europe
... avian influenza A/H5N1 virus [1]. This took place in the early spring with infected domestic birds or, occasionally, with human cases. of 2006 when infected wild birds appeared in many European There will be a steady trickle of such people coming forward with Union (EU) countries. There were confirm ...
... avian influenza A/H5N1 virus [1]. This took place in the early spring with infected domestic birds or, occasionally, with human cases. of 2006 when infected wild birds appeared in many European There will be a steady trickle of such people coming forward with Union (EU) countries. There were confirm ...
ID in the Elderly: GI,GU and Respiratory Infections
... pneumonia do not resolve 2 to 4 days after onset of the illness, and the patient is rapidly overcome by the viral illness. Alternatively, influenza may be complicated by a bacterial superinfection that often occurs 7 to 10 days after the onset of symptoms. By this time in the course of the illness, ...
... pneumonia do not resolve 2 to 4 days after onset of the illness, and the patient is rapidly overcome by the viral illness. Alternatively, influenza may be complicated by a bacterial superinfection that often occurs 7 to 10 days after the onset of symptoms. By this time in the course of the illness, ...
Ebola virus outbreaks in Africa: Past and present
... manifestations. The onset of symptoms started on 15 April 2004. The outbreak was contained rapidly with the establishment of infection control measures, thanks to the early recognition and confirmation of the outbreak by the Kenya Medical Research Institute (KEMRI). ...
... manifestations. The onset of symptoms started on 15 April 2004. The outbreak was contained rapidly with the establishment of infection control measures, thanks to the early recognition and confirmation of the outbreak by the Kenya Medical Research Institute (KEMRI). ...
press kit - Sanofi Pasteur
... authorities around the world at release stage. Producing influenza vaccines is made even more complex as influenza viruses evolve seasonally. Not all influenza is the same and a vaccine that is highly effective one year may offer only minimal protection the next year. Type A and Type B are the influ ...
... authorities around the world at release stage. Producing influenza vaccines is made even more complex as influenza viruses evolve seasonally. Not all influenza is the same and a vaccine that is highly effective one year may offer only minimal protection the next year. Type A and Type B are the influ ...
Chikungunya Fever: A New Concern For the Western Hemisphere
... only [14]. Tsetsarkin et al. [13] demonstrated that the presence of the threonine on the E1 protein at position 98 in the Asian group, supressed A. albopictus’ response to the E1-A226V mutation in this viral group. The extrinsic period for the virus in either A. aegypti or A. albopictus ranges from ...
... only [14]. Tsetsarkin et al. [13] demonstrated that the presence of the threonine on the E1 protein at position 98 in the Asian group, supressed A. albopictus’ response to the E1-A226V mutation in this viral group. The extrinsic period for the virus in either A. aegypti or A. albopictus ranges from ...
Viral RNA Patterns and High Viral Load Reliably
... per cell. Because on average the specimens contained approximately 50% tumor cells and at least 1 genome copy per cell is expected in HPV-transformed cells, we defined 0.5 copies per cell as cutoff for a high viral load (HPVhigh) and OPSCC below this cutoff had a low viral load (HPVlow). Primer seque ...
... per cell. Because on average the specimens contained approximately 50% tumor cells and at least 1 genome copy per cell is expected in HPV-transformed cells, we defined 0.5 copies per cell as cutoff for a high viral load (HPVhigh) and OPSCC below this cutoff had a low viral load (HPVlow). Primer seque ...
Influenza A virus
Influenza A virus causes influenza in birds and some mammals, and is the only species of influenza virus A. Influenza virus A is a genus of the Orthomyxoviridae family of viruses. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics.Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses.The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N1 to N11). H17 was isolated from fruit bats in 2012. H18N11 was discovered in a Peruvian bat in 2013.Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.A filtered and purified influenza A vaccine for humans has been developed, and many countries have stockpiled it to allow a quick administration to the population in the event of an avian influenza pandemic. Avian influenza is sometimes called avian flu, and colloquially, bird flu. In 2011, researchers reported the discovery of an antibody effective against all types of the influenza A virus.