• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Document
Document

... describes two alleles that are different at a specific locus. ...
Drugs - BIDD - National University of Singapore
Drugs - BIDD - National University of Singapore

... • Competitive antagonists – which compete for the agonist binding site, and require higher agonist concentration to elicit a given response. • Non-competitive agonists – these bind at a site other than the agonist binding site, or even to a completely different molecular target. The result is the lo ...
award
award

... Mental Health in order to study the neuropsychology of adult AD/HD using behavioral, structural neuroimaging, and genetic approaches. Her dissertation used a family-based genetic design to examine the relationships among AD/HD, associated neuropsychological impairments, and specific genetic influenc ...
Cardiovascular Drug Agents
Cardiovascular Drug Agents

... problems of congestive heart failure (CHF). In patients with congestive heart failure occurs when the ejection fraction compared with the total amount of blood in the ventricle is decreased. ...
File
File

... Tightly bound – released very slowly. these drugs have very long duration of action (not freed to be broken down or excreted) , slowly released into the reactive tissue. ...
Focus-on-Pharmacolog..
Focus-on-Pharmacolog..

... 11. A 77-year-old man is brought to the clinic by his daughter for a routine follow-up appointment. The daughter tells the nurse that her father is only taking half the prescribed dosage of several of his medications. What effect would the nurse explain could result from this behavior? A) Increased ...
Medication Errors - Neonatal and Paediatric Pharmacists Group
Medication Errors - Neonatal and Paediatric Pharmacists Group

... Workload/staffing levels / Rotas ...
LOMN - GeneDx
LOMN - GeneDx

... uninformative. Panel testing utilizes next generation sequencing technology, which allows for analysis of multiple genes simultaneously. This is far more cost effective and timely than stepwise genetic testing (for example, ordering testing of one or two genes followed by additional genetic tests, i ...
Psychopharm Dr Tim Lau 2010_compressed
Psychopharm Dr Tim Lau 2010_compressed

... reuptake inhibitor (still 2:1 in vivo) Higher potent affinity for 5HT and NE transporters than Effexor ...
Leukaemia Section t(15;21)(q22;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(15;21)(q22;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... DNA/RNA Transcription is from telomere to centromere Protein Contains a Runt domain and, in the C-term, a transactivation domain; forms heterodimers; widely expressed; nuclear localisation; transcription factor (activator) for various hematopoietic-specific genes. ...
Effects of Drugs on the Developing Brain
Effects of Drugs on the Developing Brain

... By Drug: Nicotine, Alcohol, Cocaine, PCP, Barbiturates, ...
drugs - Issaquah Connect
drugs - Issaquah Connect

... while urinating. While some people attempt to defeat a urine test by drinking copious amounts of water, a sufficiently diluted sample may be rejected. – Some herbal extracts are marketed for "detox" of controlled substances from one's urine, but their efficacy is controversial. FORENSIC SCIENCE: An ...
document - Herts Valleys CCG
document - Herts Valleys CCG

... 1. Patients who have not previously been treated with an Anti-VEGF injection (Anti-VEGF naïve patients) – aflibercept (preferred choice as requires fewer follow ups) and ranibizumab. 2. Patients on ranibizumab who have benefitted but require frequent injections - by local agreement, the use of aflib ...
Microarray Lessons Packet - McCarter Biology
Microarray Lessons Packet - McCarter Biology

... among them), heart medications, and pain relievers such as codeine are among this enzyme’s substrates. For codeine to exert its pain-relieving effect, it must be converted to morphine by the body. If an individual possesses genes that overproduce the enzyme, or does not produce sufficient amounts, a ...
svhs lab biology unit #6 - Sonoma Valley High School
svhs lab biology unit #6 - Sonoma Valley High School

... A) Contrast genotype and phenotype. B) Explain what is meant by the phrase “ The organisms phenotype is the expression of its genotype”. C) Contrast homozygous and heterozygous. Give examples of each. D) Define the term probability. E) Describe the formula for probability. 5) From chapter 9 pages 18 ...
Cancer Genomes for Cancer Care - The Royal Society of Edinburgh
Cancer Genomes for Cancer Care - The Royal Society of Edinburgh

STOPP START Toolkit Supporting Medication Review
STOPP START Toolkit Supporting Medication Review

... Immediate release oxybutinin should be offered to women with OAB or mixed UI if bladder training has been ineffective. There is no evidence of clinically significant differences between the ...
Document
Document

... Few of these replicated (small sample size, different methodologies) ...
Recreational Drugs - St. Joseph`s Hospital Health Center
Recreational Drugs - St. Joseph`s Hospital Health Center

... Other drugs used to combat negative effects of MJ ...
BHS 254.2 – Course 1 Date: 2/11/16 Hour 1 Nichole Conley Page
BHS 254.2 – Course 1 Date: 2/11/16 Hour 1 Nichole Conley Page

... arrhythmic drugs. They treat the arrhythmias by stabilizing the membrane and decreasing the ability of the membrane to be excited. - The cornea can also become stabilized or have a local anesthetic effect in some patients. - We can also frequently see superficial punctate keratitis with the use of B ...
Rebamipide - PIO Nas - Badan Pengawas Obat dan Makanan
Rebamipide - PIO Nas - Badan Pengawas Obat dan Makanan

... Patients should be instructed not ingest any portion of the press-through package (PTP). (There have been reports that the sharp edges of the sheet can cut or penetrate the esophageal mucosa if accidentally ingested, resulting in mediastinitis or other serious complications.) ADVERSE REACTIONS Of th ...
Introduction To Genetics
Introduction To Genetics

... C. Beyond Dominance and Recessive alleles 1. Some alleles are neither dominant nor recessive, and many traits are controlled by multiple alleles or multiple genes. 2. Cases in which one allele is not completely dominant over another are called incomplete dominance. ...
Non-Mendelian Genetics
Non-Mendelian Genetics

... • Developed by Gregor Mendel (1822-1884): studied heredity in pea plants (mainly texture and color of seeds); based solely on observations (no knowledge of DNA or meiosis) – see cartoon – Law of Segregation: there are two sets of genes for a particular trait (one from each parent), but only one gets ...
Vol 11, Issue 3: Toxicology Screening
Vol 11, Issue 3: Toxicology Screening

... screens verified by GC-MS were explained by legal use of prescription amphetamines and over-the-counter cold medications. There are immunoassays specific for methamphetamine that will not cross-react with OTC stimulant amines. ...
Audio-Digest® FAMILY PRACTICE - Audio
Audio-Digest® FAMILY PRACTICE - Audio

... surgery; reports of allergy to nonsteroidal anti-inflammatory drugs (NSAIDs); positive family history of SUD Hydromorphone (Dilaudid, Dilaudid-HP, Palladone): study saw that heroin addicts could not tell difference between dose of hydromorphone and equal dose of heroin; most reinforcing legal opioid ...
< 1 ... 981 982 983 984 985 986 987 988 989 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report