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SHEET L.13 SLIDE 5 (IV drug preparation guidelines)
SHEET L.13 SLIDE 5 (IV drug preparation guidelines)

... In HF: the first line therapy is: ACEI's, ARB's, BB's and CCB's in atrial fibrillation: the first line therapy is: amiodarone and CCB's (we have rate control and rhythm control, if we want the rate control we use CCB or BB and if we want the rhythm control we use amiodarone). Nifedipine: immediate r ...
Behavior Products and Medications
Behavior Products and Medications

... which dampens anxiety responses by stopping neural transmission and the excessive firing associated with anxiety. It can also increase serotonin and dopamine levels as well making it well suited to help in a variety of different situational and global anxiety disorders. Solliquin (Nutramax Labs)- So ...
Total knee replacement
Total knee replacement

... have had the experience of patients who have fought hard for the surgery, only to be left with complications and more pain! Knees just seem more fiddly than hips. So how do we help patients decide what is best? Joint replacements were hailed as game changing in modern medicine when they were introdu ...
What chance is there that I am a carrier? Will my children have CF if I
What chance is there that I am a carrier? Will my children have CF if I

... the baby is affected with CF. These tests can be discussed with you in more detail by a Genetic Counsellor. There are also leaflets available which tell you more about these tests. ...
2007 Guidelines for the Management of Arterial Hypertension
2007 Guidelines for the Management of Arterial Hypertension

... There is a controversial evidence as to whether blockage of the RAS has a specific beneficial role in preventing or retarding nephrosclerosis in non-diabetic non-proteinuric hypertensives (except perhaps in Afro-American individuals). However, inclusion of one of these agents in the combination ther ...
09_Development
09_Development

... and are some of the most variable (# alleles) genes known. Basis for odor-based phenotype matching in fish, mice and humans. ...
Document
Document

... agouti pattern, bands of black (or brown) and yellow pigment. Agouti hairs are produced by a dominant allele, A (agouti signal protein). Mice with genotype a/a do not produce yellow bands and have solidcolored hairs.  Ii. The B allele (encoding tyrosinaserelated protein 1) produces black pigment, w ...
Experience of an Ibogaine treatment provider
Experience of an Ibogaine treatment provider

... to lie down. The second phase (1-7 hours) is often called “the waking dream state”. The patients lie down and usually are overwhelmed by the effects of the experience: hallucinations, emotions, changes in perception of their own body, time and space. Patients feel heavy physically and experience dif ...
a 14-year-old boy with onychomycosis
a 14-year-old boy with onychomycosis

... who are concerned about treatment costs that onychomycosis is a health issue, in addition to a cosmetic issue. If the patient is symptomatic, I try to submit coverage requests to their insurance company. There was a time when the HMOs (Health Maintenance Organizations) were attempting to deny covera ...
intra-oral effects of drugs - Mid
intra-oral effects of drugs - Mid

... IV: zoledronate (Reclast) – once a year 5mg infusion for treatment of osteoporosis SQ: denosumab (Prolia) is a 60mg every six months RANKL inhibitor. Effects on bone are reversible on d/c. MOA-Bisphosphonates inhibit osteoclast precursors from attaching to the mineralized matrix which blocks transfo ...
Peer Education Training Manual
Peer Education Training Manual

... thinking that they can fly). Hallucinations: a sensory experience that does not come from external stimuli (seeing something that does not exist). ...
Shared Care Protocol for the use of Dexamfetamine
Shared Care Protocol for the use of Dexamfetamine

... Diagnosis of ADHD and decision to initiate treatment. Ensure baseline monitoring of height, weight, BP have been performed plus any additional relevant investigations such as ECG in case of family history of arrythmia or sudden death. Initiation and stabilisation of drug treatment. The GP is not exp ...
A aa - Albinizms
A aa - Albinizms

...  OCA-1, OCA-2, and OCA-3 • OCA-1: occurs on chromosome 11 •OCA-2: occurs on chromosome 15 ...
Enough of Clinical…Let’s talk Pre-Clinical!
Enough of Clinical…Let’s talk Pre-Clinical!

... activity, circulatory system, or other considerations make certain models more appropriate based on the dosage form, site of activity, or noxious metabolites. For example, canines may not be good models for solid oral dosage forms because the characteristic carnivore intestine is underdeveloped comp ...
Population Genetics and Speciation Notes
Population Genetics and Speciation Notes

SKILL SHARPENING TOOLS
SKILL SHARPENING TOOLS

... 14) What is ‘mainlining’? 15) Which is the most commonly abused drug in India? 16) What is the percentage of alcohol usually present in beer? 17) What is the name of the chemical present in alcoholic beverages? 18) Which drug can cause sudden death due to sniffing? 19) Of which drug is constipation ...
Consortium for Educational Communication Summary
Consortium for Educational Communication Summary

... cases where the law of independent assortment does not hold true. When the alleles are present on the same linkage group or chromosome, they are physically attached to each other and cannot show independent assortment. The farther apart the alleles are, however, the more likely that there will be a ...
green tea (greentee)
green tea (greentee)

... Contraindicated in: Allergy/hypersensitivity; Pregnancy and lactation (doses ⬎200 m g/day due to caffeine content). ...
Quiz 7A
Quiz 7A

... gene controls the color of the petals, but there may be several different versions (or alleles) of the gene. One version might result in red petals, while another might result in white petals. The resulting color of an individual flower will depend on which two alleles it possesses for the gene and ...
File
File

... Identical twins are genetically ______________ , so any differences between them must be due to the environment. Non-identical twins are genetically ______________ but they grew up in the same surroundings. Similarities between nonidentical twins are probably due to the ______________ . Explain why ...
Genetics Review Game
Genetics Review Game

IMPROVING THE PREDICTION OF PHARMACOGENES USING
IMPROVING THE PREDICTION OF PHARMACOGENES USING

... InWeb is a protein-protein interaction network created with data from experiments. In this work, we explored the use of drug-gene relationships mined from the literature, as an alternative knowledge source to the algorithm, in place of using the combination of relationships provided by the PharmGKB ...
slides for SMART-FHIR_rr_ga
slides for SMART-FHIR_rr_ga

... ● file : attachment // 0..* File generated from the lab for analysis ...
Learn More Series - Minot State University
Learn More Series - Minot State University

... “Strawberry quick” marks the newest form of methamphetamine to emerge within the United States. The name resembles that of a harmless powdered drink mix used to flavor milk, but the drug is just as devastating as its pure form counterpart. As with regular meth, the flavored versions can be eaten, sn ...
A “Compare and Contrast” of International Guidelines - IPAC-RS
A “Compare and Contrast” of International Guidelines - IPAC-RS

... 'Representative OINDP Specific Medical Guidelines,' indicated by an asterisk. The clinical requirements of these guidelines have been reviewed and compared and contrasted below. The IICG hope to stimulate discussion between industry, academia, and the regulators on areas of interest requiring furthe ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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