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tablet (ODT) - Rajiv Gandhi University of Health Sciences
tablet (ODT) - Rajiv Gandhi University of Health Sciences

... forms include the mentally ill, the developmentally disabled, and patients who are uncooperative, on reduced liquid-intake plans, or are nauseated. In some cases such as motion sickness, sudden episodes of allergic attack or coughing, and an unavailability of water, swallowing conventional tablets ...
stu narcotic analg..
stu narcotic analg..

... • It can also occur as a consequence of brain or nerve injury (e.g. following a stroke or herpes infection). Painful conditions of the latter kind, not directly linked to tissue injury, are very common and a major cause of disability and distress, and in general they respond less well to convention ...
Lecture 32 POWERPOINT here
Lecture 32 POWERPOINT here

... from mother and one from father. If a genetic trait is dominant, a person only needs to inherit one copy of the gene for the trait to be expressed. • Recessive - refers to an allele that causes a phenotype (visible or detectable characteristic) that is only seen in a homozygous genotype (an organism ...
| Classification of antituberculosis drugs: evidence
| Classification of antituberculosis drugs: evidence

... delamanid for ≥6 months achieved more favourable outcomes (74.5%) than those who received it for ≤2 months (55%). Additionally, the group that received a longer drug course reported less mortality (1%), compared with the short-term or no-delamanid groups (8.3%). With regards to adverse events, the Q ...
USA Product Label
USA Product Label

... Panacur® Granules 22.2% did not cause toxicity when administered to weaned pups at doses equal to 5 times the recommended daily dose and for 2 times the duration of treatment. ADVERSE REACTIONS Another benzimidazole has been reported to cause hepatoxicity clinically in canines. However, this effect ...
Original article Pill burden in HIV infection: 20 years of experience
Original article Pill burden in HIV infection: 20 years of experience

... differences in daily pill burden based on gender or other factors. ARV-experienced patients who are older than 45 years of age have higher mean daily pill burdens than patients ≤45 years of age. From 1990 to 1996 the difference was minimal but has since widened as shown in Table 3. On average, older ...
Document
Document

... of chromosomes that contain information for protein synthesis. A zygote receives twenty-three pairs of chromosomes, one of each pair from the male parent and the other of each pair from the female parent. Twenty-two of these pairs are autosomes. Autosomes are chromosomes that contain genes for the s ...
Natural selection
Natural selection

... Often went ashore to collect rocks and specimens, make observations In the Galápagos Islands he observed that species were similar to, but not the same as, species on the mainland of South America. He also realized that species varied from island to island. • This variation due to isolation from mai ...
Sex-Linked Traits
Sex-Linked Traits

... look for General format: • Example: ...
05 Lecture Evolution 09
05 Lecture Evolution 09

... Meiosis and fertilization recombine genes to yield more genetic variation. Sexual reproduction does not change genotype frequency in a population. Forces that cause change in genotype frequency (= evolution) 1) Natural Selection differentiates subpopulations ...
1 - Humble ISD
1 - Humble ISD

... between true-breeding bronze, hairy birds and true-breeding red, normal-feathered birds, what proportion of the F2 progeny will be a. Rrhh ...
High doses of lercanidipine are better tolerated than other
High doses of lercanidipine are better tolerated than other

... symptoms according to the checklist. The most frequent adverse event was ankle oedema in both groups. Almost all side effects were more prevalent in amlodipine ⁄ nifedipine GITS group. The Figure 1 shows the risk reduction for the most frequent vasodilatation-related adverse events. The classificati ...
Nanocochleate - a new approach in lipid drug delivery
Nanocochleate - a new approach in lipid drug delivery

... most  non‐hospitalized,  non‐acute  care  patients.  Drug  delivery  systems  that  allow  oral  delivery  improve  patient  compliance  and  facilitate  treatment  outside  the  hospital,  which  has  a  significant  impact  on  healthcare  economics.  Recently,  many  drug  delivery  platforms hav ...
Heredity - Net Start Class
Heredity - Net Start Class

... of chromosomes to an offspring. This is why children look similar to their parents. Furthermore, which set of chromosomes gets inherited from each parent is random. This is why siblings born from separate pregnancies look similar but not identical, and why identical twins are just that, because they ...
Sinarest LP Tab/Susp
Sinarest LP Tab/Susp

... Do not exceed the recommended dose of 2.5 mg/day in children 6 to 12 years of age. The systemic exposure with the 5 mg dose is approximately twice that of adults. The safety and effectiveness of Sinarest-LP Suspension in pediatric patients under 2 years of age have not been established. WARNINGS Sin ...
Evaluation of Potential HIV Candidate Vaccines
Evaluation of Potential HIV Candidate Vaccines

... • The ABI PRISM® 7900HT: real-time PCR system that detects & quantitates nucleic acid sequences. Automation & 384-well plate capability allow for very high-throughput. • Interchangeable formats (96 & 384 well) provide flexibility • Hand-held and integrated bar code readers simplify sample tracking • ...
Genetic variation, genetic drift (summary of
Genetic variation, genetic drift (summary of

... The Cry9C protein is effective against caterpillars because it binds to different sites of the insect gut and destroys the stomach cells. Starlink corn was approved for animals but not for humans. This protein has been found now in roughly 10% of corn tested by USDA inspectors. Several lawsuits have ...
SOC 12 - hrsbstaff.ednet.ns.ca
SOC 12 - hrsbstaff.ednet.ns.ca

... Social issues are matters that can be explained only by factors outside an individual’s control and immediate social environment. They usually concern more than a single individual and affect many individuals in a society. Social issues are contrasted with personal troubles of a given individual, ca ...
Prevention of Post-Operative Nausea and Vomiting (PONV
Prevention of Post-Operative Nausea and Vomiting (PONV

... were selected based on the strength of evidence for their clinical effectiveness. This list of selected drugs may not be current. Physicians and other health care professionals should refer to the FDA’s web site page entitled “Drug Safety Communications” for up-to-date drug recall and alert informat ...
Herb-drug interactions - Weatherford High School
Herb-drug interactions - Weatherford High School

...  “Green drinks” – clinical interactions with oncology patients. Case reports with cranberry juice also.  Multivitamins (low vitamin K dose)  CoQ10: similar structure to vitamin K, but RCT found no effect on INR. Case reports suggest monitoring. Rhode, Curr Opin Clin Nutr Metab 2007; 10:1-5 Engels ...
2 How Genes Vary in Fish Populations
2 How Genes Vary in Fish Populations

... s is 1; the phenotype is genetically lethal. There are myriad other possible selection regimes, however, which is one of the reasons that selection can be challenging to deal with. ...
Case 1 - Connect Innovate UK
Case 1 - Connect Innovate UK

...  Majority of reported abnormalities have an impact on family planning and management of subsequent pregnancies ...
Class notes
Class notes

... Punnett Squares: Used for predicting the crossing of two organisms, showing the probability of certain phenotypes/genotypes (not actual results!) Monohybrid: Looks at 1 trait at a time Dihybrid: Looks at 2 traits at a time Trihybrid: Looks at 3 traits at a time (extra credit!) Tetrahybrid: Looks at ...
Cholestasis - Yorkshire and the Humber Deanery
Cholestasis - Yorkshire and the Humber Deanery

... When do you need to worry? Decompensated cirrhosis – encephalopathy, coagulopathy  Varices – risk of bleeding, effect on first pass metabolism  Ascites – Na content, fluid retention  Cholestasis – if drug biliary cleared  Low albumin – if highly protein bound ...
We`re on the brink of a DNA revolution – where your genetic code
We`re on the brink of a DNA revolution – where your genetic code

... It’s not just about knowing how likely you are to get cancer Your health As well as indicating whether you’ll suffer from certain conditions, your genetic make-up might also influence how effective medicines will be. Your genetic code could mean not having a certain receptor on your cells, so a medi ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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