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Treatment of acute agitation in psychotic disorders
Treatment of acute agitation in psychotic disorders

... antipsychotic efficacy, sedative effects in higher doses and several decades of experience with their administration. Their limitations are well-known adverse events including acute dystonia, extrapyramidal symptoms (EPS), akathisia, hypotension and painful injection with lower potency agents such a ...
Reviewing the reality: why we need to change * Peter J. Lin Introduction
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... drug has a narrow separation of antithrombotic and haemorrhagic effects, as is the case with warfarin. This was demonstrated by a case of a 90-year-old patient treated with 5 mg of warfarin per day, who was hospitalized for gastro-intestinal bleeding with an INR of 66.31 Warfarin could still be dete ...
Pre-natal Orofacial Development - Causes of Cleft Lip and Cleft Palate
Pre-natal Orofacial Development - Causes of Cleft Lip and Cleft Palate

... descent, and Native American descent. Although when left untreated, the syndrome is usually not fatal. However, understandably, such orofacial clefts usually results in self-esteem issues later in life. Studies of genetic and/or teratogenic causes of CL/P during the pre-natal period can benefit the ...
Antineoplastic Agents - MEDICINE DEPARTMENT of MMC
Antineoplastic Agents - MEDICINE DEPARTMENT of MMC

... Cannulation Procedure: ...
Receptor-Mediated Drug Delivery to Macrophages in Chemotherapy
Receptor-Mediated Drug Delivery to Macrophages in Chemotherapy

... Mtx-MBSA killed 70% of the amastigotes for eliciting the antileishmanial activity, beof L. mexicana amazonensis (CII strain) in cause lysosomal inhibitors, chloroquine and cultured peritoneal macrophages at an Mtx monensin, effectively suppressed the leishequivalent concentration of 0.9 ,ug/ml, mani ...
Vocabulary
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... short) on the other. 3. Toss both the coins together 20 times. Record the letter combinations that you obtain from each cross. 4. Report fraction AND percentage of crosses that would results in a tall plant. ...
Ewrrsmt=~mment%
Ewrrsmt=~mment%

... action of catecholamines. one must exercise great caution with MAO inhibitors. MAO is found not only in the brain, but in other parts of the body as well. An MAO inhibitor will work on MAO in sites other than the brain. Patients who take MAO inhibitors can develop severe, even lethal, high blood pre ...
a review on dosage regimen - Indian Journal of Pharmaceutical
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Drug Use Indicators - Medicines Utilisation Research in Africa
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Fera Pharmaceuticals Launches OTC Puralube® Ophthalmic Ointment
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... Puralube, a preservative free ophthalmic ointment, is one that has been relied upon by patients and healthcare professionals for years to relieve the symptoms of dry eye. When the original manufacturer of Puralube discontinued the product, Fera was inundated with requests to bring the product back. ...
Chapter 7 - UW
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... results based on the hypothesis being tested. It must be pointed out that simply showing a set of data, how well it may be presented and how conclusive it may look, does neither support nor invalidate a hypothesis. Only the application of a statistical test, such as χ2, can tell, if a hypothesis can ...
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... Inspite of the transdermal system being highly successful in niche market, in other therapeutic application areas, the growth of this segment has not been highly commendable. There is a huge potential which is attracting the various companies in the pharmaceutical and biotechnology space. There are ...


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Inappropriate Drug Use in the Elderly
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Cannabis—A Valuable Drug That Deserves Better Treatment
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... varying concentrations of active pharmacological compounds, and certainly no other prescribed drug is administered by smoking. However, from a medical point of view, marijuana is a valuable drug. It lowers certain types of pain; has antianxiety, antiinflammatory, and antispastic effects; and enhance ...
Epilepsy genetics update 080916
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... Drug transporters have been widely studied in cancer cells, mostly due to their importance in drug resistance. Given their clinical relevance, the role of drug transporters in chemotherapy-induced peripheral neurotoxicity (CIPN) is of particular interest, but knowledge is largely incomplete in dorsa ...
analgesics
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...  indicated in case of pain of medium intensity in such conditions like other narcotic analgesics.  it can cause increasing of blood pressure and tachycardia that’s why it’s not advised to use in case of acute myocardium infarction  if it is administered for people with narcotic addiction manifest ...
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... 3. (30 points total) Self-rupturing microcapsules. Shown below is a schematic view and actual data for a recently described* self-rupturing microcapsule system for pulsatile drug delivery. The microcapsule is constructed by synthesizing a hydrogel microsphere containing an entrapped drug. The gel ...
Baclofen - UNC School of Medicine
Baclofen - UNC School of Medicine

... and drug abuse, and also covering issues on certification, reimbursement and other news of importance to public, private nonprofit and for-profit treatment agencies. Published every week except for the first Monday in July, the first Monday in September, and the first and last Mondays in December. T ...
Treating Epilepsy with newer anti-epileptic drugs
Treating Epilepsy with newer anti-epileptic drugs

Flunitrazepam
Flunitrazepam

... include sedation, muscle relaxation, reduction in anxiety, and prevention of convulsions . • However, flunitrazepam's effects are approximately 7 to 10 times more potent than diazepam. ...
2-Mohybrid Crosses
2-Mohybrid Crosses

... • The trait for blood type is an example of multiple alleles. A , B, and O are the alleles that affect blood type. • No matter how many alleles affect a characteristic one individual can only have 2 alleles at one time, – for example, ABO are all alleles for blood types but an individual can only ha ...
Awakenings (1990): The epidemic of children who fell asleep
Awakenings (1990): The epidemic of children who fell asleep

... –due to chronic motor sequellae- in the form of postencephalitis Parkinson’s disease and psychiatric disturbances. Despite the temporal association of EL and the ‘flu outbreak in 1918, analysis of the brains of affected people did not show any RNA fragment that coincided with this aetiology1. Von Ec ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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