• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Genetics[1] - Turner
Genetics[1] - Turner

... • There are multiple alleles in a population causing 4 or more phenotypes of a trait to exist • KEEP IN MIND ▫ There may be multiple alleles within the population, but individuals have only two of those alleles  Why? …because individuals have only two biological parents. We inherit half of our gene ...
Pharmacogenomics Module Presentation
Pharmacogenomics Module Presentation

... at normal doses and during normal use – Examples? • There are multiple causes for ADRs – environmental basis – genetic basis • Poor metabolizers can experience ADRs at normally therapeutic drug doses ...
Spring Newsletter April 2016
Spring Newsletter April 2016

... Quantity limits – There are quantity limits on certain medications. Most quantity limits are for narcotic medications. An amount larger that the quantity limit may be provided when there is good documentation for the need for a larger amount of the medication. The Plan usually will not allow more th ...
Rip Van Winkle Wakes Up: Development of Tuberculosis Treatment
Rip Van Winkle Wakes Up: Development of Tuberculosis Treatment

... aspects of tuberculosis treatment: treatment of latent infection, active drug-susceptible disease, and particularly, drug-resistant disease. Fortunately, at this time of great need, the field of tuberculosis drug development has reemerged after 130 years of inactivity. I review the specific needs fo ...
Mendelian genetics
Mendelian genetics

... produced smooth peas to 1 plant that produced wrinkled peas . ...
GENETIC DISORDER RESEARCH PACKET
GENETIC DISORDER RESEARCH PACKET

... proteins, you are being assigned a genetic disorder to research. Genetic disorders are caused by changes to DNA. These changes are either really small and involve only one tiny piece of DNA or really large and result in an entire missing chromosome. Either way, the affect on how someone lives their ...
Quiz 4 Thursday 4
Quiz 4 Thursday 4

... Because heart disease has an environmental component. Although dizygotic twins share the same number of genes as full siblings, twins have a more similar environment than other siblings, both in the womb and throughout their childhoods. ...
antidepressant drug overdoses
antidepressant drug overdoses

... are associated with depression, migraine, bipolar disorder, and anxiety. An antidepressant’s effectiveness and potential side effects are determined by its specificity for each neurotransmitter. The major antidepressant groups encountered in cases of accidental ingestion are tricyclic antidepressant ...
Telephone Request Service EAP Criteria
Telephone Request Service EAP Criteria

... Disclaimer: The information in this document is updated on a regular basis. Although we strive to ensure that all information is accurate at the time of posting, please be aware that some items may be subject to change from time-to-time. The information provided in this document and website is inte ...
vital statistics - Protagonist Therapeutics
vital statistics - Protagonist Therapeutics

... new drug) candidate nomination expected in 2014 • Q4 2013: advanced integrin oral peptide antagonist project from inception to preclinical development stage with IND candidate nomination expected in 2014 • 2013: raised $18M in Series B financing to fund development of an oral peptide through initiat ...
February-March 2015 - Medical Arts Pharmacy
February-March 2015 - Medical Arts Pharmacy

Genetics
Genetics

... 1. Inheritance is determined by factors (_______) that are passed from one generation to the next.  These factors (_________) have different forms, or ________________. 2. The principle of dominance: some alleles are ___________________ and others are ___________________. 3. The law of segregation: ...
International and Canadian standards
International and Canadian standards

... USA FDA • IND is drug specific. Once an IND is in place, any new trials are ‘filed’ to the IND. The FDA have 30 days to comment, but no formal approval is given (no news is good news): BUT they may issue a ‘Clinical Hold’ ...
the full-sized PDF - ERA
the full-sized PDF - ERA

... The purpose of this study is to evaluate drug use and risk behaviors among students of the University of Guayaquil in Ecuador. To evaluate this issue, we used the questionnaire “Youth Risk Behavior Survey” (YRBS). The study sample consisted of 751 undergraduate students: 328 (44%) male and 423 (56%) ...
May 2011 Issue
May 2011 Issue

... thrombin is key in the later steps of large-scale activation and aggregation. Inhibition of the PAR-1 receptor may then allow for keys steps to occur in vascular hemostasis but interrupt the process of pathologic thrombus formation. ...
Postdoctoral Associate, Department of Organic Chemistry
Postdoctoral Associate, Department of Organic Chemistry

... I was responsible for leading the company Small Molecule Drug Discovery Program which was specifically targeted at the identification and early stage evaluation (preclinical and Phase I) of novel anti-infectives.  Reporting to the VP(R&D), this senior level position was responsible for planning, ma ...
valium - Roche Canada
valium - Roche Canada

... Nursing Women: Diazepam passes into breast milk. Breast-feeding is therefore not recommended in patients receiving VALIUM. Pediatrics: Not recommended for use in children under six months. See CONTRAINDICATIONS. Geriatrics: Elderly and debilitated patients or those with organic brain disorders have ...
Guidelines for the pharmacological treatment of anxiety
Guidelines for the pharmacological treatment of anxiety

... The main side effects include dizziness and somnolence. The onset of efficacy occurs in the first days of treatment, which is an advantage over treatment with antidepressants. TCAs. The efficacy of TCAs in panic disorder and generalized anxiety disorder is well proven, mainly for imipramine and clom ...
This page
This page

... Oral contraceptives interact with many drugs, some of which make the contraceptives potentially ineffective and pregnancy can occur! Oral contraceptives may increase the risk of a woman getting cervical cancer, probably do not increase the risk of breast cancer (if given before menopause), and decre ...
Pain Management and Sedation
Pain Management and Sedation

Pediatric Warfarin Order Form INR 2-3
Pediatric Warfarin Order Form INR 2-3

...  Beta HCG for females greater than or equal to 12 years of age or post-menarche.  INR every morning.  CBC every 3 days.  Patient is on maintenance therapy:  INR if the patient is on warfarin when admitted and an INR has not been drawn in the last week.  INR weekly if patient is stabilized at g ...
product bulletin - Merck Animal Health
product bulletin - Merck Animal Health

... Sensitivity to drug-associated adverse events varies with the individual patient. Patients at greatest risk for adverse events are those that are dehydrated, on concomitant diuretic therapy, or those with existing renal, cardiovascular, and/or hepatic dysfunction. Concurrent administration of potent ...
LESCOL XL tablets
LESCOL XL tablets

... have been completely elucidated. There are multiple, alternative cytochrome P450 (CYP450) pathways for fluvastatin biotransformation and thus fluvastatin metabolism is relatively insensitive to CYP450 inhibition, a major cause of adverse drug-drug interactions. In an in vitro study with human liver ...
current use of analgesics for colic
current use of analgesics for colic

... be less with this drug though at low doses this is not considered a problem with flunixin. Anecdotal reports suggest ketoprofen is less effective as an analgesic for colic than flunixin meglumine. Eltenac has been tested in horses and has some adverse effects at 2-3 times the normal dose. Its effec ...
Pan Mersey Area Prescribing Committee
Pan Mersey Area Prescribing Committee

... of any RED drugs prescribed by the specialist clinician are recorded in individual patient records on computer systems. Please speak to your medicines management pharmacist or technician for advice on the best approach to do this.  Grey - These medicines are still being evaluated according to local ...
< 1 ... 606 607 608 609 610 611 612 613 614 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report