• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Supplemental Table 2. 2015 American Geriatrics Society Beers
Supplemental Table 2. 2015 American Geriatrics Society Beers

... Lowers seizure Avoid threshold; may be acceptable in individuals with wellcontrolled seizures in whom alternative agents have not been effective Avoid in older adults Avoid with or at high risk of delirium because of potential of inducing or worsening delirium Avoid antipsychotics for behavioral pro ...
Mendelian Genetics Review - Curwensville Area School District
Mendelian Genetics Review - Curwensville Area School District

... THE ________________________ IS BASED ON THE GENOTYPE. ...
The genomic landscape of chronic lymphocytic leukemia: clinical
The genomic landscape of chronic lymphocytic leukemia: clinical

... The results of this study suggest for the first time that LC-MBL and HC-MBL are biologically distinct entities and suggest that the increasing BcR stereotypy observed in larger clones may underpin their different clinical behaviour. It would however also be possible to contend that LC-MBL may in fa ...
Full Prescribing Information including BOXED WARNING
Full Prescribing Information including BOXED WARNING

... neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid w ...
Adverse effects
Adverse effects

... • Mechanism: Inhibits monoamine oxidase, which normally inhibits the activity of epinephrine, norepinephrine, serotonin and dopamine, and may help depression by increasing amount of norepinephrine and serotonin thus available. • Therapeutic Use: Depression. Due to potential for serious interactions ...
NEW ZEALAND DATA SHEET CLOZARIL® (clozapine) 25mgand
NEW ZEALAND DATA SHEET CLOZARIL® (clozapine) 25mgand

Genetic Testing for Tamoxifen Treatment
Genetic Testing for Tamoxifen Treatment

... Page 1 of 18 ...
Opioids for Chronic Non-Cancer Pain FAQ`s
Opioids for Chronic Non-Cancer Pain FAQ`s

... Your doctor will try to find out what is causing the pain and address it. In some situations (e.g. surgery, trauma) you may be started on an opioid immediately; in some conditions you may be on several other medications before trying opioids. The cause of pain may not be known or entirely fixable. P ...
Development and Validation of Stability-indicating RP
Development and Validation of Stability-indicating RP

... and it was found that it degrade sufficiently in acidic, alkali and oxidative condition but less degradation was found in thermal and photolytic condition. The separation was carried out on Enable G 120 A0 (250×4.6 mm, 5 µ) column having particle size 5 µ using methanol: water (75:25 v/v) with pH 4. ...
Butyrfentanyl Overdose Resulting in Diffuse Alveolar
Butyrfentanyl Overdose Resulting in Diffuse Alveolar

... problem in the United States, rivaling other major sources of morbidity and mortality, such as motor vehicle collisions.1 The burden of disease has become great enough that the US Centers for Disease Control and Prevention has declared opioid overdoses to be at epidemic levels.2 Complicating this pr ...
Genetics introduction
Genetics introduction

... •Genotype of each parent? •What is the genotypic ratio? •What is the phenotypic ratio? •What percentage of the F1 generation will have a heterozygous genotype? •What is the probability that the 5th puppy will have a pink nose? ...
Case 4 - Caangay
Case 4 - Caangay

... Mr. Reyes might have complained about constipation, muscle pain, tenderness or weakness , especially on the back, lack of energy or fever, yellowing of the skin or eyes. ...
SUSTAINED RELEASE AEROSOL FOR PULMONARY DRUG DELIVERY SYSTEM: A REVIEW
SUSTAINED RELEASE AEROSOL FOR PULMONARY DRUG DELIVERY SYSTEM: A REVIEW

... Currently the respiratory diseases are used to treat effectively through PDDS and clinically produce more beneficial effects over other route of drug administration. The inhalation of aerosol deposits the drug in pulmonary region, produces local effect and also produces the targeted drug delivery to ...
Text - Enlighten: Publications
Text - Enlighten: Publications

... related pathogens T. congolense and T. vivax [3]. In any host-pathogen relationship, variation in disease outcome can arise from differences between either hosts, pathogens, or both. In trypanosome biology, variation in parasite virulence has been well documented but the genetic basis for this has b ...
Population genetics 2
Population genetics 2

... become overrepresented in the population. Effects of selection are apparent not only at the selected locus but also in the flanking DNA sequences. If there is a lot of linkage disequilibrium (LD) like in humans, these markers can tell us a lot about the general location of particular genes. ...
MEDICATION ADHERENCE
MEDICATION ADHERENCE

... The cost of drug-related morbidity, including poor adherence, has been estimated to be up to $290 billion annually.1 ...
General Use
General Use

... Nursing Implications: ◦ Assessment  Assess pt’s mental status before / periodically  Monitor BP, pulse, resp before / frequently  Observe pt taking meds to prevent hoarding  Monitor pt for onset of akathisia, parkinsonian and dystonia, tardive dyskinesia ...
F' M a y   IO ,  1 9... ,- ,- Dr.  W illiam
F' M a y IO , 1 9... ,- ,- Dr. W illiam

... chemically related to several well-known molecules that have been used clinically for many years. PPA HCl is currently used in the OTC market in the cough/cold and anorectic areas. Current consumption is an estimated 4 to 5 billion doses annually in the United States. ...
The principles and methods formulated by Gregor
The principles and methods formulated by Gregor

... The way genes behave can easily be simulated using a penny. Tails = the recessive allele that controls pigment production (a) Heads = the dominant allele (A). Suppose a parent is heterozygous (Aa). Tossing a coin and checking for tails up vs. heads up represents the 50-50 chance that an egg or sperm ...
Misconception and Concerns about Bioidentical Hormones Used for
Misconception and Concerns about Bioidentical Hormones Used for

... two orders of magnitude after its topical application. Furthermore, the levels in capillary blood are even much higher. In addition, an antiproliferative effect on the endometrium has been reported at serum progesterone levels that were below 3.5 ng/ml. Therefore, it appears that tissue levels of pr ...
OCA2 polymorphisms associated Distribution of two with pigmentation in East-Asian populations DATA REPORT
OCA2 polymorphisms associated Distribution of two with pigmentation in East-Asian populations DATA REPORT

... information about the temporal distribution of genetic markers associated with pigmentation variation in Europe and have strengthened the case for selection operating in pigmentation-related genes in this region.20–22 Similar studies in East Asia have the potential to clarify the major events that h ...
Creatinine Clearance When Does It Matter?
Creatinine Clearance When Does It Matter?

... U.S. FDA. Center for Drug Evaluation and Research. Guidance for Industry: March 2010 Am J Kidney Dis. 2015; 65(2): 177-205 NKDEP. Chronic Kidney Disease nd Drug Dosing: Information for Providers. Jan. 2010 Kidney International 2011; 80: 1122-1137 ...
Variation and Inheritance – Revision Pack (B1) Inherited
Variation and Inheritance – Revision Pack (B1) Inherited

... Homozygous means having the same alleles (e.g. bb), while heterozygous means having different alleles (e.g. Bb). A genotype is the person’s genetic makeup, for example if they had blue eyes, their genotype would be bb. A phonotype is how this is actually seen as a characteristic, or which alleles ar ...
Genetics Test - adaptedcurriculumresources
Genetics Test - adaptedcurriculumresources

... ____ 11. Which term refers to physical characteristics that are studied in genetics? a. traits b. offspring c. generations ____ 12. The different forms of a gene are called a. alleles. b. factors. c. masks. ____ 13. An organism’s genotype is its a. genetic makeup b. feather color c. physical appeara ...
FORMULATION AND EVALUATION OF PULSATILE DRUG DELIVERY SYSTEM OF
FORMULATION AND EVALUATION OF PULSATILE DRUG DELIVERY SYSTEM OF

... Recently for local treatment of variety of colonic diseases and also for those drugs where a delay in drug absorption is required from a therapeutic point of view as in case of nocturnal asthma, arthritis and cardiac arrhythmias that are affected by circadian biorhythms 17. Apparently the colon has ...
< 1 ... 501 502 503 504 505 506 507 508 509 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report