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UMHS Information for Clinicians on the Michigan Medical Marijuana Program
UMHS Information for Clinicians on the Michigan Medical Marijuana Program

... marijuana in relieving symptoms of MS were supported by the results of early open or single-blind observations involving small numbers of patients. The most consistent finding was a subjective improvement in spasticity, but benefits for mobility, tremor, nystagmus, mood, and bladder control were als ...
ORIDA Medicaid Coverage of Medications for the Treatment of
ORIDA Medicaid Coverage of Medications for the Treatment of

... Vivitrol is covered for use in OTPs, NTPs and physician’s offices. Florida Medicaid will complete the implementation of the Statewide Medicaid Managed Care Managed Medical Assistance program by October 2014. After the implementation, managed care plans will be responsible for following the Agency’s ...
Genotypes and phenotypes
Genotypes and phenotypes

... result showed that she had cystic fibrosis (CF). CF is an inherited disorder and the gene responsible is the CFTR gene on the number-7 chromosome. The CFTR gene encodes a trans-membrane memprotein that controls the transport of chloride ions across the plasma mem transbrane. (Refer to chapter 1, pp. ...
Injectable Soft-Tissue Fillers: Clinical Overview
Injectable Soft-Tissue Fillers: Clinical Overview

... to: 1. Know the composition and biology of injectable fillers. 2. Understand the advantages and disadvantages of each injectable filler. 3. Understand the U.S. Food and Drug Administration regulatory status of each type of injectable filler, including their indications. Background: The use of inject ...
Genetic Testing for Inherited Heart Disease
Genetic Testing for Inherited Heart Disease

... cause heart disease. As with a negative result, there is still the possibility of an inherited heart condition in the family, and the recommended screening of at-risk family members should be followed. Over time, new information may become available about whether a particular gene change can cause h ...
1: gastro-intestinal system
1: gastro-intestinal system

... salivation occurs at lower doses than required for other antimuscarinic effects.4 This reduces the likelihood of undesirable effects when antimuscarinics are given to reduce salivation. In some patients, a reduction in excess saliva results in improved speech.5 To reduce the risk of undesirable effe ...
functional_enrichment_new - Baliga Lab at Institute for Systems
functional_enrichment_new - Baliga Lab at Institute for Systems

... # print table with probe ID and gene symbol >gene.symbol= toTable(hgu133plus2SYMBOL[genes.of.interest]) # print table with probe ID and gene names >gene.name= toTable(hgu133plus2GENENAME[genes.of.interest]) # Combine the information of the genes, output to csvfile: >cbind(gene.symbol,gene.name[,2]) ...
PAIN AND DRUGS USED FOR RELIEF OF PAIN
PAIN AND DRUGS USED FOR RELIEF OF PAIN

... For the Functional Pain Scale, examiners should clearly explain to the patient that functional limitations are relevant to the evaluation only if they are due to the pain being evaluated; treatment aims to relieve pain as much as possible, at least to a tolerable level (0–2). A -Demented and aphasic ...
Synthetic marijuana and acute kidney injury: an
Synthetic marijuana and acute kidney injury: an

... due to prolonged pre-renal azotemia secondary to nausea and vomiting is another possibility. However, in this case, the patient had normal pulse and blood pressure on presentation, had experienced nausea but very limited vomiting, and had not noticed any change in urine volume prior to admission. Gi ...
SYNRIBO Presciption and Services Request Form
SYNRIBO Presciption and Services Request Form

... Chronic Phase CML The median duration of exposure for the 108 patients with chronic phase CML was 7.4 months (range 0 to 43 months). The median total cycles of exposure was 6 (range 1 to 41), and the median total dose delivered during the trials was 131 mg/m2 (range 1.2 to 678). Among the patients w ...
The ABCs of Pain Management
The ABCs of Pain Management

... Review pain assessment tools for all patient populations. Identify medications that are often useful when developing a pain plan of care for hospice and palliative care patients. Identify helpful techniques to encourage positive communication between all the health care team. ...
voltaren - GuildLink
voltaren - GuildLink

... patients. Transaminase elevations were seen more frequently in patients with osteoarthritis than in those with rheumatoid arthritis (Refer to "ADVERSE REACTIONS"). Transaminase elevations were reversible on cessation of therapy, and even among patients with marked elevations, signs and symptoms of l ...
application of next generation sequencing in the diagnosis
application of next generation sequencing in the diagnosis

... also be fragile and curly. The hair is usually dry because of the absence of the oil glands. The eyebrows and eyelashes or the other body hair may absent or sparse. Any of the hair defects could manifest at birth, while others are not until later age. Nails: nail usually poorly developed on the fing ...
In understanding the affects of the psychoactive drugs to be
In understanding the affects of the psychoactive drugs to be

... Recent studies seem to indicate that there are greater physical concerns related to the use of marijuana than previously believed. The effects on the respiratory system of a single joint are equivalent to smoking fifteen cigarettes. Marijuana has at least 50% more tar and carcinogenic materials than ...
primer on genetic epidemiology
primer on genetic epidemiology

... in DZs. The calculation of the heritability is listed in Table 1. These calculations are based on the assumption that MZ pairs and DZ pairs grow up in an identical environment [27]. There is a methodological concern that twins are not representatives of the general population [28]. In practice, the ...
GMO Speaker Training Webinar
GMO Speaker Training Webinar

... anti-nutrients. ...
dexamethasone sodium phosphate - Fresenius Kabi
dexamethasone sodium phosphate - Fresenius Kabi

... doses of corticosteroids may be minimal or absent. Fat embolism has been reported as a possible complication of hypercortisonism. When large doses are given, some authorities advise that antacids be administered between meals to help prevent peptic ulcer. Steroids may increase or decrease motility a ...
Study Guide for Exam I
Study Guide for Exam I

... class we briefly discussed one type of aneuploid, the calico male cat who was XXY. A mating of a black female and an orange male could also result in a second type of aneuploid, XXX. Assume that this aneuploid inherited two X chromosomes from its mother and one X chromosome from its father. Based on ...
QUANTIFICATION OF HEALTH COMMODITIES: ARV COMPANION GUIDE Forecasting ARV Drugs Using the Morbidity
QUANTIFICATION OF HEALTH COMMODITIES: ARV COMPANION GUIDE Forecasting ARV Drugs Using the Morbidity

... Forecasts using the morbidity method rely on translating numbers of patients and services into quantities of drugs used. It is important to understand the characteristics of ARV drugs and the context in which they are prescribed in order to produce an accurate forecast. Typically, ARV drug regimens ...
Heritability and and indirect causation - Philsci
Heritability and and indirect causation - Philsci

... involving IQ. First, if parents with higher IQ give to their children both genes for higher IQ and intellectually more stimulating environment at home, this is passive G-E correlation. It is called “passive” because neither the children’s behavior nor their genotype is a causal factor that could acc ...
Chapter 11. Chemotherapy and Kidney Injury
Chapter 11. Chemotherapy and Kidney Injury

How to begin treatment in chronic heart failure? * Ronnie Willenheimer
How to begin treatment in chronic heart failure? * Ronnie Willenheimer

... absolute difference, 21.6%; 95% CI 27.6 to þ4.4%; HR, 0.94; 95% CI, 0.77–1.16; non-inferiority for bisoprolol-first vs. enalapril-first, P ¼ 0.019. Thus, the intention-to-treat analysis met the pre-specified non-inferiority limits for the upper confidence interval of þ5% for absolute difference (¼re ...
File - Spirit of Healing: Alberta First Nations Conquering
File - Spirit of Healing: Alberta First Nations Conquering

... treatments for opioid dependence as just substitutions of one addictive drug for another. People on medication-assisted treatment are not considered to be addicted – addiction is pathologic use of a substance that may or may ...
article in press - MRC
article in press - MRC

Boniva Injection
Boniva Injection

... of an intravenous dose and lasting 7 days or less. In most cases, no specific treatment was required and the symptoms subsided within 24 to 48 hours. Injection Site Reactions Local reactions at the injection site, such as redness or swelling, were observed at a higher incidence in patients treated w ...
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Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
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