• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
a review of the medicinal evidence for its therapeutic properties
a review of the medicinal evidence for its therapeutic properties

... count and to possess strong immuno-modulating properties. Guggul is one of the "broad spectrum" health products with a wide range of benefits. Mode of action makes this product very helpful not only in protecting against the common cold but also in various other conditions. It has been shown to have ...
Masking Bitter Taste of Ciprofloxacin by Microbeads
Masking Bitter Taste of Ciprofloxacin by Microbeads

... 3.2. Scanning Electron Microscopy Studies ...
Mendel Quiz 1. Who was Gregor Mendel? a) He was Charles
Mendel Quiz 1. Who was Gregor Mendel? a) He was Charles

... 4. In guinea pigs, the phenotype for fur are rough hair (dominant) and straight hair (recessive). If two heterozygous guinea pigs are crossed, the largest number of any one genotype of offspring would be a) homozygous straight hair b) homozygous rough hair c) heterozygous rough hair d) intermediate ...
Slide 1
Slide 1

... – Risk of false positive interpretation – But need only genotype “tagging” SNPs – ~ 1 million tagging SNPs will be in LD with ~50% of common variants in the human genome ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... linear. Maximum plasma concentrations are usually attained in about 2 hours, but may vary between 1 and 6 hours in different subjects. Piroxicam is eliminated largely by biotransformation, the metabolites having little or no anti-inflammatory activity. The elimination half-life is extended due to a ...
BuTrans Patch
BuTrans Patch

... result in less dsyphoria, psychological craving & dependence {However, data from Norway suggests addiction concerns}6. May cause less withdrawal when stopped than other opioids; incidence of constipation may be lower. Compared to the fentanyl patch: lower abuse potential, mild withdrawal symptoms, m ...
rowasa - Meda Pharmaceuticals
rowasa - Meda Pharmaceuticals

... kg dose, and after I.V. doses of >214 mg/kg. Mice responded similarly. In a 13-week oral (gavage) dose study in rats, the high dose of 640 mg/kg/day mesalamine caused deaths, probably due to renal failure, and dose-related renal lesions (papillary necrosis and/or multifocal tubular injury) were seen ...
Study Guide
Study Guide

Basics Pharmacology Review - Dr. Roland Halil
Basics Pharmacology Review - Dr. Roland Halil

... Morbidity Surrogate outcomes Symptomatic relief ...
Deferasirox - Therapeutic Goods Administration
Deferasirox - Therapeutic Goods Administration

... Desferrioxamine appeared more effective in the 2 to 5 years age group although the difference was not statistically significant. Success rates in this age group were 71.4% (95% CI: 54.7% - 88.2%) with desferrioxamine and 42.9% (95% CI: 24.5 – 61.2) with EXJADE. Reduced efficacy in this age group may ...
SediationAnalgesiaNursingMgt
SediationAnalgesiaNursingMgt

... Inadequate sedation and/or analgesic effect Interventions and patient response Failure to return to baseline status (within 2 points of PreAldretti score within one hour) ...
Full Prescribing Information
Full Prescribing Information

... Diluted Remodulin is administered intravenously by continuous infusion via a surgically placed indwelling central venous catheter using an infusion pump designed for intravenous drug delivery. If clinically necessary, a temporary peripheral intravenous cannula, preferably placed in a large vein, may ...
Hardy-Weinberg Lab
Hardy-Weinberg Lab

... A decimal number representing the frequency of rollers (p2 + 2pq) should be calculated by dividing the number of rollers in the class by the total number of students in the class. A decimal number representing the frequency of nonrollers (q2) can be obtained by dividing the number of nonrollers by t ...
floating bilayer tablet: a review - international journal of advances in
floating bilayer tablet: a review - international journal of advances in

... form optimized dosage form in controlled release system. By this enhancement the solubility is achieved. ENSOTROL Technology has been shown below in figure 16. 6. RoTab Bilayer RoTab bilayer when using is switched to production mode. By this technique dose and compression force is automatically regu ...
Peri-operative Management of Patients on Strong
Peri-operative Management of Patients on Strong

... opioids by the patients’ usual oral route is not possible, a suitable alternative should be utilised and the dosage adjusted accordingly for an intravenous, transdermal or epidural route. Published dose equivalency tables should be referred to when converting opioid doses. Pain assessment is fundame ...
One Step Multi-Drug, Multi-Line Screen Test Device
One Step Multi-Drug, Multi-Line Screen Test Device

... physical dependence. Withdrawal symptoms experienced during periods of drug abstinence can be severe enough to cause death. Only a small amount (less than 5%) of most Barbiturates are excreted unaltered in the urine. The approximate detection time limits for Barbiturates are: Short acting (e.g. Seco ...
Nature vs. Nurture
Nature vs. Nurture

Efalizumab in the treatment of psoriasis
Efalizumab in the treatment of psoriasis

... According to statistics provided by the manufacturer of efalizumab, at a dose of 1 mg/kg, efalizumab reduced expression of CD11 on circulating Tlymphocytes to approximately 12 to 55% of predose values and reduced free CD11a binding sites to a mean of either greater than or equal to 5% of predose val ...
JMC 5-05 PM Barriers Opioid misuse-abuse[1]
JMC 5-05 PM Barriers Opioid misuse-abuse[1]

... for Chronic Pain • Chronic non-cancer pain: evolving perspective – Consider for all patients with severe chronic pain, but weigh the influences  What is conventional practice?  Are there reasonable alternatives?  What is the risk of adverse events?  Is the patient likely to be a responsible drug ...
Treatment of Hemicrania Continua: Case Series and Literature Review
Treatment of Hemicrania Continua: Case Series and Literature Review

... worsening pain factor and sneeze was specified as an aggravating factor by one patient. There were no records of improvement factors, except for abortive medications (Table III). As the initial diagnosis was not of HC, more than one treatment option was used for each individual. Long-term indomethac ...
Materials and methods
Materials and methods

... PREPARATION AND IN VITRO EVALUATION OF FLURBIPROFEN TOPICAL GEL ...
Egg residue considerations during the treatment of backyard poultry
Egg residue considerations during the treatment of backyard poultry

Protocol: MK-0777 for the Treatment of Cognitive
Protocol: MK-0777 for the Treatment of Cognitive

... physical dependence than benzodiazepines. There are two MK-0777 formulations: i) immediate release (IR); and ii) controlled-release formulation (Gel Extrusion Module, GEM). The MK0777 GEM formulation will be used in the proposed study. MK-0777 was developed as a treatment for Generalized Anxiety Dis ...
Pumpinox Esomeprazole Tablets 20mg and 40mg
Pumpinox Esomeprazole Tablets 20mg and 40mg

... 32% increase in area under the plasma concentration-time curve (AUC) and a 31% prolongation of elimination half-life (t1/2) but no significant increase in peak plasma levels of cisapride. The slightly prolonged QTc interval observed after administration of cisapride alone, was not further prolonged ...
Drug Use During Pregnancy and Lactation
Drug Use During Pregnancy and Lactation

... – Limited data with each do not show increased risk of anomalies – Didanosine has been associated with severe lactic acidosis w/ or w/o ...
< 1 ... 411 412 413 414 415 416 417 418 419 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report