Visions 4.2 - Medications
... abnormal brain function. The journey Since the early 1950s, management of psychiatric disorders has included medication. For over 60 years, mental health and addictions researchers have been searching for ‘ideal’ medications. Medications identified during the first 30 years were far from ideal. They ...
... abnormal brain function. The journey Since the early 1950s, management of psychiatric disorders has included medication. For over 60 years, mental health and addictions researchers have been searching for ‘ideal’ medications. Medications identified during the first 30 years were far from ideal. They ...
Inhalants Information Fact Sheet
... use are due to using butane gas and aerosols. The chemicals can cause heart failure when the user does heavy exercise or experiences a lot of stress around the time of inhalant use. These are called “sudden sniffing deaths.” ...
... use are due to using butane gas and aerosols. The chemicals can cause heart failure when the user does heavy exercise or experiences a lot of stress around the time of inhalant use. These are called “sudden sniffing deaths.” ...
CONCERTATM methylphenidate HCl QUALITATIVE AND
... Gender: In healthy adults, the mean dose-adjusted AUC (0-inf) values for CONCERTA were 36.7 ng.h/mL in men and 37.1 ng.h/mL in women, with no differences noted between the two groups. Race: In adults receiving CONCERTA, dose-adjusted AUC (0-inf) was consistent across ethnic groups; however, the samp ...
... Gender: In healthy adults, the mean dose-adjusted AUC (0-inf) values for CONCERTA were 36.7 ng.h/mL in men and 37.1 ng.h/mL in women, with no differences noted between the two groups. Race: In adults receiving CONCERTA, dose-adjusted AUC (0-inf) was consistent across ethnic groups; however, the samp ...
SALIX PHARMACEUTICALS LTD (Form: 8-K
... three once-daily oral methylnaltrexone dosing regimens (150, 300 and 450mg), demonstrated highly statistically significant results for the primary endpoint in two of the three treatment arms when compared to the placebo treatment arm. Both the 300 and 450 mg treatment arms demonstrated highly statis ...
... three once-daily oral methylnaltrexone dosing regimens (150, 300 and 450mg), demonstrated highly statistically significant results for the primary endpoint in two of the three treatment arms when compared to the placebo treatment arm. Both the 300 and 450 mg treatment arms demonstrated highly statis ...
Thesis - CiteSeerX
... made to reduce the prescribing of antipsychotic drugs to older adults with dementia. We found a higher use of antipsychotic drugs among persons with lower levels of education, both among persons with and without dementia. Lower socioeconomic position seems to be positively associated with a higher u ...
... made to reduce the prescribing of antipsychotic drugs to older adults with dementia. We found a higher use of antipsychotic drugs among persons with lower levels of education, both among persons with and without dementia. Lower socioeconomic position seems to be positively associated with a higher u ...
The Health Effect of Psychostimulants: A Literature Review
... methamphetamine in the professional context has been observed. A certain plant, khat, is used in specific societies in east-Africa for its psychostimulant properties. Psychostimulants (e.g. sibutramine) can be prescribed to lower appetite in obesity. This can be considered the pharmacologic part of ...
... methamphetamine in the professional context has been observed. A certain plant, khat, is used in specific societies in east-Africa for its psychostimulant properties. Psychostimulants (e.g. sibutramine) can be prescribed to lower appetite in obesity. This can be considered the pharmacologic part of ...
Stevens Johnson Syndrome
... Case-control study. The international case-control study was designed to (according to the reporter and coded by a standard system), the type of reactions (up to 4 per case), the drugs and biologics to which the patient was estimate the risks of SIS and TEN in association with all drugs. The study a ...
... Case-control study. The international case-control study was designed to (according to the reporter and coded by a standard system), the type of reactions (up to 4 per case), the drugs and biologics to which the patient was estimate the risks of SIS and TEN in association with all drugs. The study a ...
weight loss
... people regain weight over time. Alarmingly, this traditional approach does not decrease the incidence of cardiovascular events in obese adults with T2D,and may not be adequate for maintaining improved insulin sensitivity or b-cell function. ...
... people regain weight over time. Alarmingly, this traditional approach does not decrease the incidence of cardiovascular events in obese adults with T2D,and may not be adequate for maintaining improved insulin sensitivity or b-cell function. ...
... biological knowledge. In crop genetics and evolution, various forms of genetic markers viz. morphological, biochemical, cytogenetic and molecular markers are used to unveil genetic diversity in crop plants [7]. Diversity studies using genetic markers reveal polymorphisms and provide insights about c ...
March 2016
... The PBAC did not recommend the PBS listing of denosumab for hypercalcaemia of malignancy on the basis of that the submission’s clinical data did not support the claim of superior efficacy, relative to bisphosphonates, and the lack of a clear clinical place for denosumab. The PBAC noted the submissio ...
... The PBAC did not recommend the PBS listing of denosumab for hypercalcaemia of malignancy on the basis of that the submission’s clinical data did not support the claim of superior efficacy, relative to bisphosphonates, and the lack of a clear clinical place for denosumab. The PBAC noted the submissio ...
FTR 2012-3:Layout 1
... therapy modalities are used either alone or in combination with other rehabilitation techniques, and drug therapies to reduce pain and to improve function. It has been demonstrated that glucosamine and chondroitin sulfate are low-toxicity agents that reduce pain and stiffness associated with OA (6,7 ...
... therapy modalities are used either alone or in combination with other rehabilitation techniques, and drug therapies to reduce pain and to improve function. It has been demonstrated that glucosamine and chondroitin sulfate are low-toxicity agents that reduce pain and stiffness associated with OA (6,7 ...
NIDA InfoFacts: Steroids (Anabolic-Androgenic)
... The immediate effects of AAS in the brain are mediated by their binding to androgen (male sex hormone) and estrogen (female sex hormone) receptors on the surface of a cell. This AAS–receptor complex can then shuttle into the cell nucleus to influence patterns of gene expression. Because of this, the ...
... The immediate effects of AAS in the brain are mediated by their binding to androgen (male sex hormone) and estrogen (female sex hormone) receptors on the surface of a cell. This AAS–receptor complex can then shuttle into the cell nucleus to influence patterns of gene expression. Because of this, the ...
TCI: TOOL OR TOY
... equilibrium or the rate at which the drug enters the brain.(4) This makes it possible to incorporate pharmacodynamics (PD) in models. ...
... equilibrium or the rate at which the drug enters the brain.(4) This makes it possible to incorporate pharmacodynamics (PD) in models. ...
Read "FDA Violation of the Rule of Law"
... solvent. That is anti-freeze. Although Massengill was convicted of gross negligence, the Roosevelt administration, feeling its oats after the "switch in time that saved nine," called for adoption of the Food, Drug and C osmetic Act of 1938. That law required companies to submit New Drug Applications ...
... solvent. That is anti-freeze. Although Massengill was convicted of gross negligence, the Roosevelt administration, feeling its oats after the "switch in time that saved nine," called for adoption of the Food, Drug and C osmetic Act of 1938. That law required companies to submit New Drug Applications ...
Does Combined Antipsychotic Treatment Provide Better Control on
... of atypical antipsychotics to the physicians. The clinicians’ choice for the combination therapy rather than initiating a single drug at a high dose may be explained by the fact that the high-dose antipsychotic administration may result in severe and acute adverse effects, such as cardiac problems a ...
... of atypical antipsychotics to the physicians. The clinicians’ choice for the combination therapy rather than initiating a single drug at a high dose may be explained by the fact that the high-dose antipsychotic administration may result in severe and acute adverse effects, such as cardiac problems a ...
A role for genetic accommodation in evolution?
... instead of a single pair. In short, Gibson and Hogness found that the differential phenotypic expression of the etherinduced bithorax phenotype is caused by genetic polymorphisms in the Ubx (Ultrabithorax) gene, with the loss of expression of the UBX protein in the third thoracic imaginal discs corr ...
... instead of a single pair. In short, Gibson and Hogness found that the differential phenotypic expression of the etherinduced bithorax phenotype is caused by genetic polymorphisms in the Ubx (Ultrabithorax) gene, with the loss of expression of the UBX protein in the third thoracic imaginal discs corr ...
Epidural Anesthesia and Analgesia
... If in the epidural space, there should be little to no resistance when injecting. Initially a small amount of air or saline can be injected as a test. There should be no resistance. The plunger should always advance and not retract so as to refill the syringe. An alternative method is called the han ...
... If in the epidural space, there should be little to no resistance when injecting. Initially a small amount of air or saline can be injected as a test. There should be no resistance. The plunger should always advance and not retract so as to refill the syringe. An alternative method is called the han ...
Optimal Use of Bendamustine in Chronic Lymphocytic Leukemia
... Bendamustine is a novel bifunctional alkylating agent with promising activity in lymphoid malignancies and several solid tumors. Unfortunately, the early development of this agent did not provide sufficient information on which to determine an optimal systematic dose and schedule. As a result, admini ...
... Bendamustine is a novel bifunctional alkylating agent with promising activity in lymphoid malignancies and several solid tumors. Unfortunately, the early development of this agent did not provide sufficient information on which to determine an optimal systematic dose and schedule. As a result, admini ...
product monograph
... In clinical trials comparing NEULASTA to filgrastim, medullary bone pain was reported in 26% of NEULASTA-treated patients, which was comparable to the incidence in filgrastim-treated patients. In the study comparing NEULASTA to placebo, the incidence of bone pain was 23% vs. 16%, respectively. This ...
... In clinical trials comparing NEULASTA to filgrastim, medullary bone pain was reported in 26% of NEULASTA-treated patients, which was comparable to the incidence in filgrastim-treated patients. In the study comparing NEULASTA to placebo, the incidence of bone pain was 23% vs. 16%, respectively. This ...
Cats with Runny Eyes. Treatment of Feline Herpes Virus Infections
... to the virus, and more than 80% are carriers (1, 2). Cats are infected after direct or indirect contact with sick or carrier animals; the infection occurs through the oronasal and conjunctival routes. Clinical signs of active disease include conjunctivitis and keratitis with ulceration (early, super ...
... to the virus, and more than 80% are carriers (1, 2). Cats are infected after direct or indirect contact with sick or carrier animals; the infection occurs through the oronasal and conjunctival routes. Clinical signs of active disease include conjunctivitis and keratitis with ulceration (early, super ...
Use of Rifabutin in the Treatment of Pulmonary Tuberculosis
... The criteria used to assess efficacy were the same for all five studies. Sputum samples were collected prior to initiation of drug therapy, fortnightly for the first 2 months of therapy, and then at weeks 12, 16, and 24 (and 36 in the Spanish study). Therapeutic efficacy was evaluated by assessment ...
... The criteria used to assess efficacy were the same for all five studies. Sputum samples were collected prior to initiation of drug therapy, fortnightly for the first 2 months of therapy, and then at weeks 12, 16, and 24 (and 36 in the Spanish study). Therapeutic efficacy was evaluated by assessment ...
University of Groningen Species and strain differences in drug
... predict the metabolic behaviour of new compounds in human. It is however important to realize that humans differ from animals with regard to isoform composition, expression and catalytic activities of drug metabolizing enzymes. In this review we aim to describe similarities and differences in this r ...
... predict the metabolic behaviour of new compounds in human. It is however important to realize that humans differ from animals with regard to isoform composition, expression and catalytic activities of drug metabolizing enzymes. In this review we aim to describe similarities and differences in this r ...
Deep-HepRenSyn-Terlipressin - Pediatric Continuous Renal
... • Co-interventions included albumin, fresh frozen plasma, and cimetidine • Terlipressin reduced mortality rates by 34% • The control group mortality rate was 65% • Terlipressin improved renal function assessed by creatinine clearance, serum creatinine and urine output. ...
... • Co-interventions included albumin, fresh frozen plasma, and cimetidine • Terlipressin reduced mortality rates by 34% • The control group mortality rate was 65% • Terlipressin improved renal function assessed by creatinine clearance, serum creatinine and urine output. ...
Alien Alleles Objective: Predict the phenotype of offspring based on
... Objective: Predict the phenotype of offspring based on the genotype of inherited alleles. Background: An allele is a location on a gene that codes for a particular trait. Each person (or alien) receives one allele from the mother and one allele from the father. Dominant alleles are always expressed, ...
... Objective: Predict the phenotype of offspring based on the genotype of inherited alleles. Background: An allele is a location on a gene that codes for a particular trait. Each person (or alien) receives one allele from the mother and one allele from the father. Dominant alleles are always expressed, ...