Research Report Series from the director:
... result from chronic drug exposure or that happen when an addicted person is exposed to drugassociated “cues” that can trigger craving and lead to relapse. By mapping the genetic factors and brain regions responsible for the multiple effects of cocaine, these new technologies can help us identify ne ...
... result from chronic drug exposure or that happen when an addicted person is exposed to drugassociated “cues” that can trigger craving and lead to relapse. By mapping the genetic factors and brain regions responsible for the multiple effects of cocaine, these new technologies can help us identify ne ...
Annex Ib : Final CSP (clean version)
... clinical importance, and are generally not a consideration for the discontinuation of epirubicin treatment. Late (i.e., Delayed) Events. Delayed cardiotoxicity usually develops late in the course of therapy with epirubicin or within 2 to 3 months after treatment termination, but later events (severa ...
... clinical importance, and are generally not a consideration for the discontinuation of epirubicin treatment. Late (i.e., Delayed) Events. Delayed cardiotoxicity usually develops late in the course of therapy with epirubicin or within 2 to 3 months after treatment termination, but later events (severa ...
The Effect of Chronic Morphine or Methadone Exposure and
... from the SCN (Baler et al. 1997, Simonneaux et al. 2006). It has been shown that the increase in Aanat mRNA expression is followed by an increase in AA-NAT enzymatic activity, and this in turn is tightly correlated with the changes in melatonin synthesis (Zatz et al. 2000, Klein et al. 1997). Opioid ...
... from the SCN (Baler et al. 1997, Simonneaux et al. 2006). It has been shown that the increase in Aanat mRNA expression is followed by an increase in AA-NAT enzymatic activity, and this in turn is tightly correlated with the changes in melatonin synthesis (Zatz et al. 2000, Klein et al. 1997). Opioid ...
Medical Cannabis for Aging - Americans for Safe Access
... We are committed to ensuring safe, legal availability of marijuana for medical uses. This brochure is intended to help doctors, patients and policymakers better understand how marijuana—or "cannabis" as it is more properly called—may be used as a treatment for people with serious medical conditions. ...
... We are committed to ensuring safe, legal availability of marijuana for medical uses. This brochure is intended to help doctors, patients and policymakers better understand how marijuana—or "cannabis" as it is more properly called—may be used as a treatment for people with serious medical conditions. ...
Product Monograph - AstraZeneca Canada
... Platelet transfusion did not reverse the antiplatelet effect of BRILINTA in healthy volunteers and is unlikely to be of clinical benefit in patients with bleeding. Since co-administration of BRILINTA with desmopressin did not decrease template bleeding time, desmopressin is unlikely to be effective ...
... Platelet transfusion did not reverse the antiplatelet effect of BRILINTA in healthy volunteers and is unlikely to be of clinical benefit in patients with bleeding. Since co-administration of BRILINTA with desmopressin did not decrease template bleeding time, desmopressin is unlikely to be effective ...
Product Monograph Template - Standard
... breast-feed if they are receiving CELSENTRI because of both the potential for HIV transmission and any possible undesirable effects in nursing infants. Pediatrics (<18 years of age): The pharmacokinetics, safety and efficacy of maraviroc in pediatric patients have not been established. Therefore, ma ...
... breast-feed if they are receiving CELSENTRI because of both the potential for HIV transmission and any possible undesirable effects in nursing infants. Pediatrics (<18 years of age): The pharmacokinetics, safety and efficacy of maraviroc in pediatric patients have not been established. Therefore, ma ...
Recommendations of the Italian Society for Rheumatology for the
... points improved significantly in the infliximab group compared with the baseline value, with no improvement in the placebo group. There was one drugrelated case of disseminated tuberculosis. In 54-week, open-label study, 10 patients treated with infliximab (5 mg/kg at weeks 0, 2, 6 and at individual ...
... points improved significantly in the infliximab group compared with the baseline value, with no improvement in the placebo group. There was one drugrelated case of disseminated tuberculosis. In 54-week, open-label study, 10 patients treated with infliximab (5 mg/kg at weeks 0, 2, 6 and at individual ...
Pain Part 1
... “sick” people who take narcotics for their psychodelic effects become addicted. Those taking it for pain do not. morphine self-administration studies the people vs. Larry Flynt ...
... “sick” people who take narcotics for their psychodelic effects become addicted. Those taking it for pain do not. morphine self-administration studies the people vs. Larry Flynt ...
This reprint contains information which is not found in the FDA
... failure to thrive, respiratory problems (wheezing, asthma, or recurrent pneumonia), abdominal pain, irritability, and sleeping problems (4–6). These symptoms, if not treated in time, may lead to complications and can severely affect the quality of life of these children and their families (7). There ...
... failure to thrive, respiratory problems (wheezing, asthma, or recurrent pneumonia), abdominal pain, irritability, and sleeping problems (4–6). These symptoms, if not treated in time, may lead to complications and can severely affect the quality of life of these children and their families (7). There ...
Local Anesthesia in Dentistry
... The metabolism of the two drugs is also different. As for the metabolism of articaine, a small amount (10%) is handled by the liver, but about 90% is hydrolyzed in the serum by non-specific blood esterases.14 In contrast, lidocaine is predominantly metabolized in the liver (70%) in a relatively slow ...
... The metabolism of the two drugs is also different. As for the metabolism of articaine, a small amount (10%) is handled by the liver, but about 90% is hydrolyzed in the serum by non-specific blood esterases.14 In contrast, lidocaine is predominantly metabolized in the liver (70%) in a relatively slow ...
Resistance to First-Line Anti-TB Drugs is Associated with Reduced Nitric Oxide
... The main finding of this study is that reduced susceptibility to NO in clinical strains of M. tuberculosis was associated with resistance to first-line drugs against TB. As previously reported, certain strains of M. tuberculosis can to some extent resist RNS generated in vitro as acidified nitrite ( ...
... The main finding of this study is that reduced susceptibility to NO in clinical strains of M. tuberculosis was associated with resistance to first-line drugs against TB. As previously reported, certain strains of M. tuberculosis can to some extent resist RNS generated in vitro as acidified nitrite ( ...
PREPARATION AND EVALUATION OF NOVEL TOPICAL GEL PREPARATIONS FOR WOUND
... neuropathy which may lead to foot ulceration6. Diabetic foot ulcers frequently become infected and are a major cause of hospital admissions. They also account for more than half of nontraumatic lower limb amputations in this patient population7,8 . For these reasons, it is important to manage diabet ...
... neuropathy which may lead to foot ulceration6. Diabetic foot ulcers frequently become infected and are a major cause of hospital admissions. They also account for more than half of nontraumatic lower limb amputations in this patient population7,8 . For these reasons, it is important to manage diabet ...
product monograph - Eli Lilly Canada
... Somatropin can increase the extrathyroidal conversion of thyroxine (T4) to triiodothyronine (T3) and may unmask incipient hypothyroidism. Because inadequate treatment of hypothyroidism may prevent optimal response to somatropin, thyroid function should be evaluated before starting somatropin therapy ...
... Somatropin can increase the extrathyroidal conversion of thyroxine (T4) to triiodothyronine (T3) and may unmask incipient hypothyroidism. Because inadequate treatment of hypothyroidism may prevent optimal response to somatropin, thyroid function should be evaluated before starting somatropin therapy ...
Pan London Cytotoxic Policy
... to. As some pregnancies are unplanned, or staff unwilling to discuss plans for conception, the emphasis must be on the reduction of exposure for all staff at all times. There have been some studies suggesting adverse effects on the foetus as a result of the mother working with cytotoxic drugs. Many ...
... to. As some pregnancies are unplanned, or staff unwilling to discuss plans for conception, the emphasis must be on the reduction of exposure for all staff at all times. There have been some studies suggesting adverse effects on the foetus as a result of the mother working with cytotoxic drugs. Many ...
MPH 510-Phenylketonuria
... public health professional’s perspective. Genetic screening is a sensitive topic. Some people feel genetic screening may lead to discrimination of individuals who possess “inferior” genes. It is known that employers and some insurance companies want to asses people based off of their genetic composi ...
... public health professional’s perspective. Genetic screening is a sensitive topic. Some people feel genetic screening may lead to discrimination of individuals who possess “inferior” genes. It is known that employers and some insurance companies want to asses people based off of their genetic composi ...
Adverse Event Terminology
... Important medical events that may not result in death, be life-threatening, or require hospitalization may be considered serious when, based upon appropriate medical judgment, they may jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the outcomes l ...
... Important medical events that may not result in death, be life-threatening, or require hospitalization may be considered serious when, based upon appropriate medical judgment, they may jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the outcomes l ...
network models for genetic testing
... Genomics is a relatively new scientific field that studies how genes are related to human health and disease [5]. The core technology that transformed genetic research, helped understanding genetic factors and led to prevention of birth defects and disabilities is DNA sequencing. However, the contin ...
... Genomics is a relatively new scientific field that studies how genes are related to human health and disease [5]. The core technology that transformed genetic research, helped understanding genetic factors and led to prevention of birth defects and disabilities is DNA sequencing. However, the contin ...
Multiple Avirulence Loci and Allele-Specific Effector
... by molecular cloning (Yahiaoui et al., 2004, 2006; Srichumpa et al., 2005). In comparison, the Mla alleles share 84.6% sequence identity and show a similar divergence as the Arabidopsis RPP13 and the flax L alleles (Rose et al., 2004; Seeholzer et al., 2010; Ravensdale et al., 2012). Interestingly, s ...
... by molecular cloning (Yahiaoui et al., 2004, 2006; Srichumpa et al., 2005). In comparison, the Mla alleles share 84.6% sequence identity and show a similar divergence as the Arabidopsis RPP13 and the flax L alleles (Rose et al., 2004; Seeholzer et al., 2010; Ravensdale et al., 2012). Interestingly, s ...
Click here B. Pharmacy Syllabus
... (INTRODUCTION TO DOSAGE FORMS) THEORY Max. Marks: 80 Total Hours: 50 (2hrs/week) Note: Examiner to set eight questions and the candidates are required to attempt any five. 1. Introduction: Importance and classification of Pharmaceutical dosage forms, Sources of information required for Pharmacists. ...
... (INTRODUCTION TO DOSAGE FORMS) THEORY Max. Marks: 80 Total Hours: 50 (2hrs/week) Note: Examiner to set eight questions and the candidates are required to attempt any five. 1. Introduction: Importance and classification of Pharmaceutical dosage forms, Sources of information required for Pharmacists. ...
Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB
... Nevertheless, clinical experience on linezolid has been mainly restricted to case reports and small case series including both non-tuberculous mycobacterial diseases and TB [22–29]. Due to the lack of available antibiotics to treat such difficult cases, linezolid is already used off-label to treat M ...
... Nevertheless, clinical experience on linezolid has been mainly restricted to case reports and small case series including both non-tuberculous mycobacterial diseases and TB [22–29]. Due to the lack of available antibiotics to treat such difficult cases, linezolid is already used off-label to treat M ...
Chronic Urticaria and Angioedema - The Division of Allergy and
... recommended doses of these agents. A study of 439 patients revealed that fexofenadine, at a dose of 60, 120, or 240 mg per day, was significantly more efficacious than placebo, as assessed by the mean pruritus score, the mean number of wheals per day, the mean daily symptom score (the sum of the whe ...
... recommended doses of these agents. A study of 439 patients revealed that fexofenadine, at a dose of 60, 120, or 240 mg per day, was significantly more efficacious than placebo, as assessed by the mean pruritus score, the mean number of wheals per day, the mean daily symptom score (the sum of the whe ...
Propranolol - Plymouth | Veterinary Surgeons
... Tell your vet if you are giving your pet any other medications, even if you think they already know. This includes herbal or offthe-shelf remedies from a pet shop or pharmacy. Do not give propranolol to your pet if they are already taking any of a group of drugs called sympathomimetics (these includ ...
... Tell your vet if you are giving your pet any other medications, even if you think they already know. This includes herbal or offthe-shelf remedies from a pet shop or pharmacy. Do not give propranolol to your pet if they are already taking any of a group of drugs called sympathomimetics (these includ ...
Procedure
... certain forces act on the population. Dominant alleles will not replace recessive alleles, and the ratio of heterozygous and homozygous individuals does not change over the course of several generations. This theory has come to be known as the Hardy-Weinberg principal; it is the basis of the study o ...
... certain forces act on the population. Dominant alleles will not replace recessive alleles, and the ratio of heterozygous and homozygous individuals does not change over the course of several generations. This theory has come to be known as the Hardy-Weinberg principal; it is the basis of the study o ...